Published in Mol Biol Cell on June 16, 2010
AAA+: A class of chaperone-like ATPases associated with the assembly, operation, and disassembly of protein complexes. Genome Res (1999) 11.30
Jasplakinolide, a cytotoxic natural product, induces actin polymerization and competitively inhibits the binding of phalloidin to F-actin. J Biol Chem (1994) 5.67
A role for the lissencephaly gene LIS1 in mitosis and cytoplasmic dynein function. Nat Cell Biol (2000) 5.29
Genome-wide prediction of C. elegans genetic interactions. Science (2006) 4.15
Cytoplasmic dynein is required for distinct aspects of MTOC positioning, including centrosome separation, in the one cell stage Caenorhabditis elegans embryo. J Cell Biol (1999) 3.97
A LIS1/NUDEL/cytoplasmic dynein heavy chain complex in the developing and adult nervous system. Neuron (2000) 3.93
Ultrastructural analysis of the dynactin complex: an actin-related protein is a component of a filament that resembles F-actin. J Cell Biol (1994) 3.74
Cytoplasmic dynein and dynactin in cell division and intracellular transport. Curr Opin Cell Biol (1999) 3.63
Multiple nucleotide-binding sites in the sequence of dynein beta heavy chain. Nature (1991) 3.36
Dynein: An ancient motor protein involved in multiple modes of transport. J Neurobiol (2004) 3.30
An extended microtubule-binding structure within the dynein motor domain. Nature (1997) 2.93
Role of dynein, dynactin, and CLIP-170 interactions in LIS1 kinetochore function. J Cell Biol (2002) 2.89
Regulation of cytoplasmic dynein behaviour and microtubule organization by mammalian Lis1. Nat Cell Biol (2000) 2.81
LIS1, CLIP-170's key to the dynein/dynactin pathway. Mol Cell Biol (2002) 2.61
Four ATP-binding sites in the midregion of the beta heavy chain of dynein. Nature (1991) 2.59
The dynein microtubule motor. Biochim Biophys Acta (2000) 2.45
Molecular motors: strategies to get along. Curr Biol (2004) 2.41
Dynein from Dictyostelium: primary structure comparisons between a cytoplasmic motor enzyme and flagellar dynein. J Cell Biol (1992) 2.37
Capping protein levels influence actin assembly and cell motility in dictyostelium. Cell (1995) 2.15
Differential localization and sequence analysis of capping protein beta-subunit isoforms of vertebrates. J Cell Biol (1994) 2.00
Capping protein: new insights into mechanism and regulation. Trends Biochem Sci (2004) 1.71
MEX-3 interacting proteins link cell polarity to asymmetric gene expression in Caenorhabditis elegans. Development (2002) 1.57
Functional analysis of cytoplasmic dynein heavy chain in Caenorhabditis elegans with fast-acting temperature-sensitive mutations. Mol Biol Cell (2004) 1.52
Dynein modifiers in C. elegans: light chains suppress conditional heavy chain mutants. PLoS Genet (2007) 1.47
Jasplakinolide's inhibition of the growth of prostate carcinoma cells in vitro with disruption of the actin cytoskeleton. J Natl Cancer Inst (1995) 1.44
Disregulated RhoGTPases and actin cytoskeleton contribute to the migration defect in Lis1-deficient neurons. J Neurosci (2003) 1.38
Regulation of cytoplasmic dynein ATPase by Lis1. J Neurosci (2006) 1.37
lis-1 is required for dynein-dependent cell division processes in C. elegans embryos. J Cell Sci (2004) 1.22
Dictyostelium LIS1 is a centrosomal protein required for microtubule/cell cortex interactions, nucleus/centrosome linkage, and actin dynamics. Mol Biol Cell (2005) 1.20
Cytoplasmic dynein light intermediate chain is required for discrete aspects of mitosis in Caenorhabditis elegans. Mol Biol Cell (2001) 1.18
Lis1, the Drosophila homolog of a human lissencephaly disease gene, is required for germline cell division and oocyte differentiation. Development (1999) 1.18
Jasplakinolide, a novel actin targeting peptide, inhibits cell growth and induces actin filament polymerization in the green alga Micrasterias. Cell Motil Cytoskeleton (1997) 1.17
A balance of capping protein and profilin functions is required to regulate actin polymerization in Drosophila bristle. Mol Biol Cell (2003) 1.03
Point mutations in the stem region and the fourth AAA domain of cytoplasmic dynein heavy chain partially suppress the phenotype of NUDF/LIS1 loss in Aspergillus nidulans. Genetics (2007) 0.95
Progression from mitotic catastrophe to germ cell death in Caenorhabditis elegans lis-1 mutants requires the spindle checkpoint. Dev Biol (2007) 0.83
Systemic RNAi in C. elegans requires the putative transmembrane protein SID-1. Science (2002) 4.72
Composition and dynamics of the Caenorhabditis elegans early embryonic transcriptome. Development (2003) 3.49
Transport of dsRNA into cells by the transmembrane protein SID-1. Science (2003) 3.08
An antiviral role for the RNA interference machinery in Caenorhabditis elegans. Proc Natl Acad Sci U S A (2005) 2.16
Caenorhabditis elegans SID-2 is required for environmental RNA interference. Proc Natl Acad Sci U S A (2007) 1.85
The homeodomain protein PAL-1 specifies a lineage-specific regulatory network in the C. elegans embryo. Development (2005) 1.68
SID-5 is an endosome-associated protein required for efficient systemic RNAi in C. elegans. Curr Biol (2012) 1.62
MEX-3 interacting proteins link cell polarity to asymmetric gene expression in Caenorhabditis elegans. Development (2002) 1.57
Environmental RNA interference. Trends Genet (2008) 1.54
Export of RNA silencing from C. elegans tissues does not require the RNA channel SID-1. Proc Natl Acad Sci U S A (2009) 1.51
Synthetic lethal analysis of Caenorhabditis elegans posterior embryonic patterning genes identifies conserved genetic interactions. Genome Biol (2005) 1.33
SID-1 is a dsRNA-selective dsRNA-gated channel. RNA (2011) 1.33
The STAR/Maxi-KH domain protein GLD-1 mediates a developmental switch in the translational control of C. elegans PAL-1. Development (2004) 1.17
Transport of sequence-specific RNA interference information between cells. Annu Rev Genet (2007) 1.16
Comparison of diverse developmental transcriptomes reveals that coexpression of gene neighbors is not evolutionarily conserved. Genome Res (2009) 1.08
Cyclic tensile strain triggers a sequence of autocrine and paracrine signaling to regulate angiogenic sprouting in human vascular cells. Proc Natl Acad Sci U S A (2009) 1.06
Translational control of maternal RNAs. WormBook (2005) 1.04
Uptake of extracellular double-stranded RNA by SID-2. Mol Cell (2012) 1.02
The SID-1 double-stranded RNA transporter is not selective for dsRNA length. RNA (2009) 1.02
Two classes of silencing RNAs move between Caenorhabditis elegans tissues. Nat Struct Mol Biol (2011) 1.00
Tissue specificity of Caenorhabditis elegans enhanced RNA interference mutants. Genetics (2011) 0.98
Mutations in a beta-tubulin disrupt spindle orientation and microtubule dynamics in the early Caenorhabditis elegans embryo. Mol Biol Cell (2003) 0.97
Pairing of competitive and topologically distinct regulatory modules enhances patterned gene expression. Mol Syst Biol (2008) 0.95
A genome-wide RNAi screen in Caenorhabditis elegans identifies the nicotinic acetylcholine receptor subunit ACR-7 as an antipsychotic drug target. PLoS Genet (2013) 0.91
Composition and regulation of maternal and zygotic transcriptomes reflects species-specific reproductive mode. Genome Biol (2010) 0.90
A genomic bias for genotype-environment interactions in C. elegans. Mol Syst Biol (2012) 0.90
Clozapine interaction with phosphatidyl inositol 3-kinase (PI3K)/insulin-signaling pathway in Caenorhabditis elegans. Neuropsychopharmacology (2009) 0.90
RNA interference in Caenorhabditis elegans: uptake, mechanism, and regulation. Parasitology (2011) 0.89
Conserved tyrosine kinase promotes the import of silencing RNA into Caenorhabditis elegans cells. Proc Natl Acad Sci U S A (2012) 0.86
Semi-supervised analysis of gene expression profiles for lineage-specific development in the Caenorhabditis elegans embryo. Bioinformatics (2006) 0.86
The nuclear argonaute NRDE-3 contributes to transitive RNAi in Caenorhabditis elegans. Genetics (2013) 0.86
Progression from mitotic catastrophe to germ cell death in Caenorhabditis elegans lis-1 mutants requires the spindle checkpoint. Dev Biol (2007) 0.83
MyoD, modularity, and myogenesis: conservation of regulators and redundancy in C. elegans. Genes Dev (2006) 0.83
Behavioral effects of clozapine: involvement of trace amine pathways in C. elegans and M. musculus. Brain Res (2011) 0.82
The relevance of Caenorhabditis elegans genetics for understanding human psychiatric disease. Harv Rev Psychiatry (2011) 0.82
Transient receptor potential melastatin (TRPM) channels mediate clozapine-induced phenotypes in Caenorhabditis elegans. J Neurogenet (2014) 0.81
The Influence of Competition Among C. elegans Small RNA Pathways on Development. Genes (Basel) (2012) 0.79
Assays for direct and indirect effects of C. elegans endo-siRNAs. Methods Mol Biol (2014) 0.77
Regulation of neuronal lineage decisions by the HES-related bHLH protein REF-1. Dev Biol (2005) 0.77
Vampiric isolation of extracellular fluid from Caenorhabditis elegans. J Vis Exp (2012) 0.75