Published in Development on July 01, 2010
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Robo2 acts in trans to inhibit Slit-Robo1 repulsion in pre-crossing commissural axons. Elife (2015) 0.91
The secreted AdamTS-A metalloprotease is required for collective cell migration. Development (2013) 0.88
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Regulation of ECM degradation and axon guidance by growth cone invadosomes. Development (2015) 0.83
Drosophila MMP2 regulates the matrix molecule faulty attraction (Frac) to promote motor axon targeting in Drosophila. J Neurosci (2011) 0.82
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Dscam1 Forms a Complex with Robo1 and the N-Terminal Fragment of Slit to Promote the Growth of Longitudinal Axons. PLoS Biol (2016) 0.77
The Intracellular Domain of the Frazzled/DCC Receptor Is a Transcription Factor Required for Commissural Axon Guidance. Neuron (2015) 0.77
Raised plasma Robo4 and cardiac surgery-associated acute kidney injury. PLoS One (2014) 0.77
Slit Binding via the Ig1 Domain Is Essential for Midline Repulsion by Drosophila Robo1 but Dispensable for Receptor Expression, Localization, and Regulation in Vivo. G3 (Bethesda) (2015) 0.76
Amontillado is required for Drosophila Slit processing and for tendon-mediated muscle patterning. Biol Open (2016) 0.76
Cell adhesion and invasion mechanisms that guide developing axons. Curr Opin Neurobiol (2016) 0.75
Natural and laboratory mutations in kuzbanian are associated with zinc stress phenotypes in Drosophila melanogaster. Sci Rep (2017) 0.75
Commissural axon navigation: Control of midline crossing in the vertebrate spinal cord by the semaphorin 3B signaling. Cell Adh Migr (2016) 0.75
C-terminal Src Kinase Gates Homeostatic Synaptic Plasticity and Regulates Fasciclin II Expression at the Drosophila Neuromuscular Junction. PLoS Genet (2016) 0.75
Genetic specification of left-right asymmetry in the diaphragm muscles and their motor innervation. Elife (2017) 0.75
Regulation of Drosophila Brain Wiring by Neuropil Interactions via a Slit-Robo-RPTP Signaling Complex. Dev Cell (2016) 0.75
In vivo functional analysis of Drosophila Robo1 immunoglobulin-like domains. Neural Dev (2016) 0.75
The Amyloid Precursor Protein Is a Conserved Receptor for Slit to Mediate Axon Guidance. eNeuro (2017) 0.75
Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development (1993) 58.26
Notch signaling: from the outside in. Dev Biol (2000) 6.06
Slit proteins bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance. Cell (1999) 5.42
Slit is the midline repellent for the robo receptor in Drosophila. Cell (1999) 4.29
Roundabout controls axon crossing of the CNS midline and defines a novel subfamily of evolutionarily conserved guidance receptors. Cell (1998) 4.00
Kuzbanian controls proteolytic processing of Notch and mediates lateral inhibition during Drosophila and vertebrate neurogenesis. Cell (1997) 3.48
Adam meets Eph: an ADAM substrate recognition module acts as a molecular switch for ephrin cleavage in trans. Cell (2005) 3.34
Regulated cleavage of a contact-mediated axon repellent. Science (2000) 3.24
Biochemical purification of a mammalian slit protein as a positive regulator of sensory axon elongation and branching. Cell (1999) 2.80
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Regulation of commissural axon pathfinding by slit and its Robo receptors. Annu Rev Cell Dev Biol (2006) 2.76
Processing of the notch ligand delta by the metalloprotease Kuzbanian. Science (1999) 2.71
Mutations affecting growth cone guidance in Drosophila: genes necessary for guidance toward or away from the midline. Neuron (1993) 2.65
Slit stimulation recruits Dock and Pak to the roundabout receptor and increases Rac activity to regulate axon repulsion at the CNS midline. Neuron (2003) 2.39
Substrate specificity of gamma-secretase and other intramembrane proteases. Cell Mol Life Sci (2008) 2.29
slit: an extracellular protein necessary for development of midline glia and commissural axon pathways contains both EGF and LRR domains. Genes Dev (1990) 2.25
Comm function in commissural axon guidance: cell-autonomous sorting of Robo in vivo. Nat Neurosci (2005) 2.09
Switching repulsion to attraction: changing responses to slit during transition in mesoderm migration. Science (2001) 1.98
Comm sorts robo to control axon guidance at the Drosophila midline. Cell (2002) 1.98
Structural aspects of the metzincin clan of metalloendopeptidases. Mol Biotechnol (2003) 1.87
Slit proteins: key regulators of axon guidance, axonal branching, and cell migration. Curr Opin Neurobiol (2000) 1.85
The Notch ligand Delta1 is sequentially cleaved by an ADAM protease and gamma-secretase. Proc Natl Acad Sci U S A (2003) 1.85
Chimeric axon guidance receptors: the cytoplasmic domains of slit and netrin receptors specify attraction versus repulsion. Cell (1999) 1.83
Mechanisms through which Sos-1 coordinates the activation of Ras and Rac. J Cell Biol (2002) 1.60
Diversity and specificity of actions of Slit2 proteolytic fragments in axon guidance. J Neurosci (2001) 1.51
Dosage-sensitive and complementary functions of roundabout and commissureless control axon crossing of the CNS midline. Neuron (1998) 1.50
Control of neuronal pathway selection by the Drosophila LIM homeodomain gene apterous. Development (1995) 1.42
Slit and Robo control cardiac cell polarity and morphogenesis. Curr Biol (2005) 1.41
Axon guidance at the midline: from mutants to mechanisms. Crit Rev Biochem Mol Biol (2005) 1.34
The ADAMs family: coordinators of nervous system development, plasticity and repair. Prog Neurobiol (2006) 1.30
Son of sevenless directly links the Robo receptor to rac activation to control axon repulsion at the midline. Neuron (2006) 1.30
Biochemical properties and functions of membrane-anchored metalloprotease-disintegrin proteins (ADAMs). Curr Top Dev Biol (2003) 1.26
Lateral positioning at the dorsal midline: Slit and Roundabout receptors guide Drosophila heart cell migration. Proc Natl Acad Sci U S A (2006) 1.26
The cell surface metalloprotease/disintegrin Kuzbanian is required for axonal extension in Drosophila. Proc Natl Acad Sci U S A (1996) 1.26
Independent functions of Slit-Robo repulsion and Netrin-Frazzled attraction regulate axon crossing at the midline in Drosophila. J Neurosci (2007) 1.12
Axon repulsion from the midline of the Drosophila CNS requires slit function. Development (1999) 1.07
The function of leak and kuzbanian during growth cone and cell migration. Mech Dev (2001) 0.98
Role of Slit proteins in the vertebrate brain. J Physiol Paris (2001) 0.96
Live dissection and surface labeling of proteins in Drosophila embryos. Cold Spring Harb Protoc (2010) 5.09
Visualizing axons in the Drosophila central nervous system using immunohistochemistry and immunofluorescence. Cold Spring Harb Protoc (2010) 5.08
Slit stimulation recruits Dock and Pak to the roundabout receptor and increases Rac activity to regulate axon repulsion at the CNS midline. Neuron (2003) 2.39
Axon growth and guidance: receptor regulation and signal transduction. Annu Rev Neurosci (2009) 2.20
A frazzled/DCC-dependent transcriptional switch regulates midline axon guidance. Science (2009) 1.79
Discoidin domain receptor 2 regulates fibroblast proliferation and migration through the extracellular matrix in association with transcriptional activation of matrix metalloproteinase-2. J Biol Chem (2001) 1.51
Axon guidance at the midline: from mutants to mechanisms. Crit Rev Biochem Mol Biol (2005) 1.34
Son of sevenless directly links the Robo receptor to rac activation to control axon repulsion at the midline. Neuron (2006) 1.30
Cross GTPase-activating protein (CrossGAP)/Vilse links the Roundabout receptor to Rac to regulate midline repulsion. Proc Natl Acad Sci U S A (2005) 1.28
Axon guidance at the midline: of mice and flies. Curr Opin Neurobiol (2010) 1.16
Ectopic expression in the giant fiber system of Drosophila reveals distinct roles for roundabout (Robo), Robo2, and Robo3 in dendritic guidance and synaptic connectivity. J Neurosci (2002) 1.16
The homeobox transcription factor even-skipped regulates netrin-receptor expression to control dorsal motor-axon projections in Drosophila. Curr Biol (2005) 1.13
Independent functions of Slit-Robo repulsion and Netrin-Frazzled attraction regulate axon crossing at the midline in Drosophila. J Neurosci (2007) 1.12
Functional diversity of Robo receptor immunoglobulin domains promotes distinct axon guidance decisions. Curr Biol (2010) 1.03
Cytoplasmic domain requirements for Frazzled-mediated attractive axon turning at the Drosophila midline. Development (2007) 1.01
beta-Spectrin functions independently of Ankyrin to regulate the establishment and maintenance of axon connections in the Drosophila embryonic CNS. Development (2006) 0.93
Slit/Robo-mediated axon guidance in Tribolium and Drosophila: divergent genetic programs build insect nervous systems. Dev Biol (2012) 0.90
A GATA/homeodomain transcriptional code regulates axon guidance through the Unc-5 receptor. Development (2012) 0.86
Transcriptional regulation of guidance at the midline and in motor circuits. Cell Mol Life Sci (2013) 0.84
Src inhibits midline axon crossing independent of Frazzled/Deleted in Colorectal Carcinoma (DCC) receptor tyrosine phosphorylation. J Neurosci (2013) 0.83
Distinct functional domains of the Abelson tyrosine kinase control axon guidance responses to Netrin and Slit to regulate the assembly of neural circuits. Development (2013) 0.80