Published in Mol Biol Evol on June 23, 2010
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Evolution of the sweet taste receptor gene Tas1r2 in bats. Mol Biol Evol (2010) 1.36
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Loss or major reduction of umami taste sensation in pinnipeds. Naturwissenschaften (2012) 0.87
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Differentiated adaptive evolution, episodic relaxation of selective constraints, and pseudogenization of umami and sweet taste genes TAS1Rs in catarrhine primates. Front Zool (2014) 0.81
The loss of taste genes in cetaceans. BMC Evol Biol (2014) 0.79
Evolutionary genomics of fast evolving tunicates. Genome Biol Evol (2014) 0.79
Identification and expression dynamics of three WUSCHEL related homeobox 13 (WOX13) genes in peanut. Dev Genes Evol (2015) 0.78
Relaxed selective constraints drove functional modifications in peripheral photoreception of the cavefish P. andruzzii and provide insight into the time of cave colonization. Heredity (Edinb) (2016) 0.78
Molecular evolution of the CYP2D subfamily in primates: purifying selection on substrate recognition sites without the frequent or long-tract gene conversion. Genome Biol Evol (2015) 0.78
Dietary specialization drives multiple independent losses and gains in the bitter taste gene repertoire of Laurasiatherian Mammals. Front Zool (2016) 0.77
Similarities and differences between "proactive" and "passive" stress-coping rats in responses to sucrose, NaCl, citric acid, and quinine. Chem Senses (2014) 0.75
Evolution of Digestive Enzymes and RNASE1 Provides Insights into Dietary Switch of Cetaceans. Mol Biol Evol (2016) 0.75
Loss of gene function and evolution of human phenotypes. BMB Rep (2015) 0.75
Identification of protein-damaging mutations in 10 swine taste receptors and 191 appetite-reward genes. BMC Genomics (2016) 0.75
Fatal Toxoplasma gondii infection in the giant panda. Parasite (2015) 0.75
The genome of the largest bony fish, ocean sunfish (Mola mola), provides insights into its fast growth rate. Gigascience (2016) 0.75
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The sequence and de novo assembly of the giant panda genome. Nature (2009) 15.76
Mammalian sweet taste receptors. Cell (2001) 8.04
The receptors for mammalian sweet and umami taste. Cell (2003) 6.79
An amino-acid taste receptor. Nature (2002) 6.71
The receptors and cells for mammalian taste. Nature (2006) 6.32
Mitochondrial genomes reveal an explosive radiation of extinct and extant bears near the Miocene-Pliocene boundary. BMC Evol Biol (2008) 3.21
Slow molecular clocks in Old World monkeys, apes, and humans. Mol Biol Evol (2002) 2.20
Evolutionary deterioration of the vomeronasal pheromone transduction pathway in catarrhine primates. Proc Natl Acad Sci U S A (2003) 2.14
Contrasting modes of evolution between vertebrate sweet/umami receptor genes and bitter receptor genes. Mol Biol Evol (2005) 1.77
Pseudogenization of a sweet-receptor gene accounts for cats' indifference toward sugar. PLoS Genet (2005) 1.49
A molecular solution to the riddle of the giant panda's phylogeny. Nature (1985) 1.43
Pattern and timing of diversification of the mammalian order Carnivora inferred from multiple nuclear gene sequences. Mol Phylogenet Evol (2010) 1.39
Evolution of the sweet taste receptor gene Tas1r2 in bats. Mol Biol Evol (2010) 1.36
Extreme variability among mammalian V1R gene families. Genome Res (2009) 1.31
Positive selection on protein-length in the evolution of a primate sperm ion channel. Proc Natl Acad Sci U S A (2003) 1.26
Characterization of ligands for fish taste receptors. J Neurosci (2007) 1.26
Mitogenomic analyses of caniform relationships. Mol Phylogenet Evol (2007) 1.25
The first skull of the earliest giant panda. Proc Natl Acad Sci U S A (2007) 1.08
Phylogeny of the bears (Ursidae) based on nuclear and mitochondrial genes. Mol Phylogenet Evol (2004) 0.94
Morphological study of the lingual papillae of the giant panda (Ailuropoda melanoleuca) by scanning electron microscopy. J Anat (2008) 0.87
Rapid subfunctionalization accompanied by prolonged and substantial neofunctionalization in duplicate gene evolution. Genetics (2005) 3.98
MicroRNA-101, down-regulated in hepatocellular carcinoma, promotes apoptosis and suppresses tumorigenicity. Cancer Res (2009) 3.83
Evolutionary conservation of expression profiles between human and mouse orthologous genes. Mol Biol Evol (2005) 3.62
Gene sequence-based criteria for identification of new rickettsia isolates and description of Rickettsia heilongjiangensis sp. nov. J Clin Microbiol (2003) 3.59
The pleiotropic structure of the genotype-phenotype map: the evolvability of complex organisms. Nat Rev Genet (2011) 3.57
Why do hubs tend to be essential in protein networks? PLoS Genet (2006) 3.29
Gene losses during human origins. PLoS Biol (2006) 3.17
RNA sequencing shows no dosage compensation of the active X-chromosome. Nat Genet (2010) 2.71
Null mutations in human and mouse orthologs frequently result in different phenotypes. Proc Natl Acad Sci U S A (2008) 2.60
A functional polymorphism in the miR-146a gene is associated with the risk for hepatocellular carcinoma. Carcinogenesis (2008) 2.37
Balanced codon usage optimizes eukaryotic translational efficiency. PLoS Genet (2012) 2.32
Impacts of gene essentiality, expression pattern, and gene compactness on the evolutionary rate of mammalian proteins. Mol Biol Evol (2006) 2.22
Genomic patterns of pleiotropy and the evolution of complexity. Proc Natl Acad Sci U S A (2010) 2.19
Prevalent positive epistasis in Escherichia coli and Saccharomyces cerevisiae metabolic networks. Nat Genet (2010) 2.16
Mouse duplicate genes are as essential as singletons. Trends Genet (2007) 2.12
More genes underwent positive selection in chimpanzee evolution than in human evolution. Proc Natl Acad Sci U S A (2007) 2.00
Low rates of expression profile divergence in highly expressed genes and tissue-specific genes during mammalian evolution. Mol Biol Evol (2006) 1.97
Dramatic variation of the vomeronasal pheromone receptor gene repertoire among five orders of placental and marsupial mammals. Proc Natl Acad Sci U S A (2005) 1.88
Toward a molecular understanding of pleiotropy. Genetics (2006) 1.88
Comparative genomic analysis identifies an evolutionary shift of vomeronasal receptor gene repertoires in the vertebrate transition from water to land. Genome Res (2007) 1.85
Adaptive diversification of bitter taste receptor genes in Mammalian evolution. Mol Biol Evol (2003) 1.82
MicroRNA-26a/b and their host genes cooperate to inhibit the G1/S transition by activating the pRb protein. Nucleic Acids Res (2011) 1.79
Contrasting modes of evolution between vertebrate sweet/umami receptor genes and bitter receptor genes. Mol Biol Evol (2005) 1.77
Expression of hiwi gene in human gastric cancer was associated with proliferation of cancer cells. Int J Cancer (2006) 1.76
The hearing gene Prestin unites echolocating bats and whales. Curr Biol (2010) 1.62
Higher duplicability of less important genes in yeast genomes. Mol Biol Evol (2005) 1.57
Maintenance of duplicate genes and their functional redundancy by reduced expression. Trends Genet (2010) 1.51
Composition and evolution of the V2r vomeronasal receptor gene repertoire in mice and rats. Genomics (2005) 1.47
Impact of gene expression noise on organismal fitness and the efficacy of natural selection. Proc Natl Acad Sci U S A (2011) 1.46
The ribonuclease A superfamily of mammals and birds: identifying new members and tracing evolutionary histories. Genomics (2005) 1.43
Sex-specific splicing of the honeybee doublesex gene reveals 300 million years of evolution at the bottom of the insect sex-determination pathway. Genetics (2007) 1.43
Gene complexity and gene duplicability. Curr Biol (2005) 1.42
Relaxation of selective constraint and loss of function in the evolution of human bitter taste receptor genes. Hum Mol Genet (2004) 1.38
In search of the biological significance of modular structures in protein networks. PLoS Comput Biol (2007) 1.38
The genomic landscape and evolutionary resolution of antagonistic pleiotropy in yeast. Cell Rep (2012) 1.36
Evolution of the sweet taste receptor gene Tas1r2 in bats. Mol Biol Evol (2010) 1.36
Impact of translational error-induced and error-free misfolding on the rate of protein evolution. Mol Syst Biol (2010) 1.35
Origin of the genetic components of the vomeronasal system in the common ancestor of all extant vertebrates. Mol Biol Evol (2008) 1.33
Measuring the evolutionary rate of protein-protein interaction. Proc Natl Acad Sci U S A (2011) 1.32
MicroRNA let-7c inhibits migration and invasion of human non-small cell lung cancer by targeting ITGB3 and MAP4K3. Cancer Lett (2013) 1.31
Positive selection for elevated gene expression noise in yeast. Mol Syst Biol (2009) 1.30
Protein misinteraction avoidance causes highly expressed proteins to evolve slowly. Proc Natl Acad Sci U S A (2012) 1.29
Genomic and genetic evidence for the loss of umami taste in bats. Genome Biol Evol (2011) 1.27
Did brain-specific genes evolve faster in humans than in chimpanzees? Trends Genet (2006) 1.26
Positive selection on protein-length in the evolution of a primate sperm ion channel. Proc Natl Acad Sci U S A (2003) 1.26
Gene dosage and gene duplicability. Genetics (2008) 1.23
Abundant indispensable redundancies in cellular metabolic networks. Genome Biol Evol (2009) 1.23
Expression reduction in mammalian X chromosome evolution refutes Ohno's hypothesis of dosage compensation. Proc Natl Acad Sci U S A (2012) 1.22
Rapid turnover and species-specificity of vomeronasal pheromone receptor genes in mice and rats. Gene (2004) 1.21
p37 from Mycoplasma hyorhinis promotes cancer cell invasiveness and metastasis through activation of MMP-2 and followed by phosphorylation of EGFR. Mol Cancer Ther (2008) 1.21
Genomic evidence for elevated mutation rates in highly expressed genes. EMBO Rep (2012) 1.19
Largest vertebrate vomeronasal type 1 receptor gene repertoire in the semiaquatic platypus. Mol Biol Evol (2007) 1.19
Why are some human disease-associated mutations fixed in mice? Trends Genet (2003) 1.19
Why is the correlation between gene importance and gene evolutionary rate so weak? PLoS Genet (2009) 1.16
On the definition and measurement of pleiotropy. Trends Genet (2013) 1.14
Distinct evolutionary patterns between chemoreceptors of 2 vertebrate olfactory systems and the differential tuning hypothesis. Mol Biol Evol (2008) 1.13
No gene-specific optimization of mutation rate in Escherichia coli. Mol Biol Evol (2013) 1.13
Coexpression of linked genes in Mammalian genomes is generally disadvantageous. Mol Biol Evol (2008) 1.12
Nonneutral evolution of the transcribed pseudogene Makorin1-p1 in mice. Mol Biol Evol (2004) 1.11
Neuronal protein synuclein gamma predicts poor clinical outcome in breast cancer. Int J Cancer (2007) 1.10
Differential requirements for mRNA folding partially explain why highly expressed proteins evolve slowly. Proc Natl Acad Sci U S A (2013) 1.09
The Complete Mitochondrial Genome of Ctenoptilum vasava (Lepidoptera: Hesperiidae: Pyrginae) and Its Phylogenetic Implication. Comp Funct Genomics (2012) 1.09
Diet shapes the evolution of the vertebrate bitter taste receptor gene repertoire. Mol Biol Evol (2013) 1.08
Positive selection for indel substitutions in the rodent sperm protein catsper1. Mol Biol Evol (2005) 1.07
Contrasting genetic paths to morphological and physiological evolution. Proc Natl Acad Sci U S A (2010) 1.05
Evolution of the complementary sex-determination gene of honey bees: balancing selection and trans-species polymorphisms. Genome Res (2006) 1.04
The ortholog conjecture is untestable by the current gene ontology but is supported by RNA sequencing data. PLoS Comput Biol (2012) 1.02
Impact of extracellularity on the evolutionary rate of mammalian proteins. Genome Biol Evol (2010) 1.02
Generation of novel monoclonal antibodies and their application for detecting ARD1 expression in colorectal cancer. Cancer Lett (2008) 1.02
High expression hampers horizontal gene transfer. Genome Biol Evol (2012) 1.01
Evaluation of transovarial transmission and transmissibility of Ehrlichia chaffeensis (Rickettsiales: Anaplasmataceae) in Amblyomma americanum (Acari: Ixodidae). J Med Entomol (2003) 1.01
Suppression of tumor growth and metastasis by a VEGFR-1 antagonizing peptide identified from a phage display library. Int J Cancer (2004) 1.01
Evolutionary dynamics of nematode operons: easy come, slow go. Genome Res (2008) 1.00
Remarkable expansions of an X-linked reproductive homeobox gene cluster in rodent evolution. Genomics (2006) 1.00
Protein subcellular relocalization in the evolution of yeast singleton and duplicate genes. Genome Biol Evol (2009) 0.99
Gain dynamics of a free-space nitrogen laser pumped by circularly polarized femtosecond laser pulses. Opt Express (2014) 0.96
Human coding RNA editing is generally nonadaptive. Proc Natl Acad Sci U S A (2014) 0.96
Zebrafish ribonucleases are bactericidal: implications for the origin of the vertebrate RNase A superfamily. Mol Biol Evol (2007) 0.95
Rapid evolution of mammalian X-linked testis-expressed homeobox genes. Genetics (2004) 0.93
Molecular diversity of Chaerilidae venom peptides reveals the dynamic evolution of scorpion venom components from Buthidae to non-Buthidae. J Proteomics (2013) 0.92
Evidence for escape from adaptive conflict? Nature (2009) 0.91
Low-threshold whispering-gallery-mode microlasers fabricated in a Nd:glass substrate by three-dimensional femtosecond laser micromachining. Opt Lett (2013) 0.90
Diagnosis of gastric cancer using decision tree classification of mass spectral data. Cancer Sci (2007) 0.90
Origin and evolution of the vertebrate vomeronasal system viewed through system-specific genes. Bioessays (2006) 0.90
A big world inside small-world networks. PLoS One (2009) 0.90
Widespread losses of vomeronasal signal transduction in bats. Mol Biol Evol (2010) 0.89
Critical power and clamping intensity inside a filament in a flame. Opt Express (2016) 0.89
Processed pseudogenes: the 'fossilized footprints' of past gene expression. Trends Genet (2009) 0.89
Ancient expansion of the ribonuclease A superfamily revealed by genomic analysis of placental and marsupial mammals. Gene (2006) 0.88
Positive selection drives the evolution of bat bitter taste receptor genes. Biochem Genet (2009) 0.87
Explosive photodissociation of methane induced by ultrafast intense laser. J Chem Phys (2006) 0.87
Attosecond-recollision-controlled selective fragmentation of polyatomic molecules. Phys Rev Lett (2012) 0.86
Impulsive rotational Raman scattering of N2 by a remote "air laser" in femtosecond laser filament. Opt Lett (2014) 0.86
Mismatches between feeding ecology and taste receptor evolution: an inconvenient truth. Proc Natl Acad Sci U S A (2012) 0.85