Loss of estrogen receptor 1 enhances cervical cancer invasion.

PubWeight™: 1.01‹?› | Rank: Top 15%

🔗 View Article (PMC 2913367)

Published in Am J Pathol on June 25, 2010

Authors

Yali Zhai1, Guido T Bommer, Ying Feng, Alexandra B Wiese, Eric R Fearon, Kathleen R Cho

Author Affiliations

1: Department of Pathology, University of Michigan Medical School, Ann Arbor, MI 48109-2200, USA.

Articles citing this

Decorin causes autophagy in endothelial cells via Peg3. Proc Natl Acad Sci U S A (2013) 1.22

Molecular transitions from papillomavirus infection to cervical precancer and cancer: Role of stromal estrogen receptor signaling. Proc Natl Acad Sci U S A (2015) 1.06

Requirement for stromal estrogen receptor alpha in cervical neoplasia. Horm Cancer (2012) 1.00

HRAS mutations are frequent in inverted urothelial neoplasms. Hum Pathol (2014) 0.96

Gallic acid reduces cell viability, proliferation, invasion and angiogenesis in human cervical cancer cells. Oncol Lett (2013) 0.93

Requirement of estrogen receptor alpha DNA-binding domain for HPV oncogene-induced cervical carcinogenesis in mice. Carcinogenesis (2013) 0.81

The inhibitor of Ca(2+)-dependent K+ channels TRAM-34 blocks growth of hepatocellular carcinoma cells via downregulation of estrogen receptor alpha mRNA and nuclear factor-kappaB. Invest New Drugs (2012) 0.80

Methylator phenotype of malignant germ cell tumours in children identifies strong candidates for chemotherapy resistance. Br J Cancer (2011) 0.80

In search of novel drug target sites on estrogen receptors using RNA aptamers. Nucleic Acid Ther (2014) 0.80

Targeting female hormone receptors as cervical cancer therapy. Trends Endocrinol Metab (2015) 0.79

Epithelial estrogen receptor 1 intrinsically mediates squamous differentiation in the mouse vagina. Proc Natl Acad Sci U S A (2015) 0.77

Network Topologies Decoding Cervical Cancer. PLoS One (2015) 0.76

The cervical malignant cells display a down regulation of ER-α but retain the ER-β expression. Int J Clin Exp Pathol (2013) 0.76

ERα Mediates Estrogen-Induced Expression of the Breast Cancer Metastasis Suppressor Gene BRMS1. Int J Mol Sci (2016) 0.75

Investigation of differentially-expressed microRNAs and genes in cervical cancer using an integrated bioinformatics analysis. Oncol Lett (2017) 0.75

Articles cited by this

Global cancer statistics, 2002. CA Cancer J Clin (2005) 119.22

The polycomb group protein EZH2 is involved in progression of prostate cancer. Nature (2002) 18.30

MethPrimer: designing primers for methylation PCRs. Bioinformatics (2002) 14.48

EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells. Proc Natl Acad Sci U S A (2003) 13.68

The SLUG zinc-finger protein represses E-cadherin in breast cancer. Cancer Res (2002) 6.47

Natural history of cervical intraepithelial neoplasia: a critical review. Int J Gynecol Pathol (1993) 4.67

Methylation of the estrogen receptor gene CpG island marks loss of estrogen receptor expression in human breast cancer cells. Cancer Res (1994) 3.18

2006 consensus guidelines for the management of women with cervical intraepithelial neoplasia or adenocarcinoma in situ. Am J Obstet Gynecol (2007) 2.97

Estrogens and their receptors in breast cancer progression: a dual role in cancer proliferation and invasion. Crit Rev Oncol Hematol (2004) 2.34

Downregulation of EZH2 decreases growth of estrogen receptor-negative invasive breast carcinoma and requires BRCA1. Oncogene (2008) 2.31

Spontaneous regression of high-grade cervical dysplasia: effects of human papillomavirus type and HLA phenotype. Clin Cancer Res (2005) 2.21

Integration of estrogen and Wnt signaling circuits by the polycomb group protein EZH2 in breast cancer cells. Mol Cell Biol (2007) 2.14

Utility of methylation markers in cervical cancer early detection: appraisal of the state-of-the-science. Gynecol Oncol (2008) 2.08

The transcription factor snail mediates epithelial to mesenchymal transitions by repression of estrogen receptor-alpha. Mol Endocrinol (2007) 1.95

Mapping of ER gene CpG island methylation-specific polymerase chain reaction. Cancer Res (1998) 1.91

Development of a sensitive and specific assay combining multiplex PCR and DNA microarray primer extension to detect high-risk mucosal human papillomavirus types. J Clin Microbiol (2006) 1.61

Gene expression analysis of preinvasive and invasive cervical squamous cell carcinomas identifies HOXC10 as a key mediator of invasion. Cancer Res (2007) 1.53

Activation of estrogen receptor transfected into a receptor-negative breast cancer cell line decreases the metastatic and invasive potential of the cells. Proc Natl Acad Sci U S A (1992) 1.48

Comparison of five different polymerase chain reaction methods for detection of human papillomavirus in cervical cell specimens. J Virol Methods (2000) 1.44

Aging, methylation and cancer. Histol Histopathol (2000) 1.40

Activation of the enhancer of zeste homologue 2 gene by the human papillomavirus E7 oncoprotein. Cancer Res (2008) 1.38

HPV-18 immortalization of human keratinocytes. Virology (1989) 1.35

Sequential gene promoter methylation during HPV-induced cervical carcinogenesis. Br J Cancer (2007) 1.32

Expression levels of estrogen receptor-alpha, estrogen receptor-beta, coactivators, and corepressors in breast cancer. Clin Cancer Res (2000) 1.30

Assessment of gene promoter hypermethylation for detection of cervical neoplasia. Int J Cancer (2006) 1.23

Requirement for estrogen receptor alpha in a mouse model for human papillomavirus-associated cervical cancer. Cancer Res (2008) 1.21

Enhancer of Zeste 2 as a marker of preneoplastic progression in the breast. Cancer Res (2006) 1.13

Immunohistochemical analysis of estrogen receptors, progesterone receptors, Ki-67 antigen, and human papillomavirus DNA in normal and neoplastic epithelium of the uterine cervix. Cancer (1991) 1.01

Detection of human papillomaviruses in cervical neoplasias using multiple sets of generic polymerase chain reaction primers. Gynecol Oncol (2001) 0.99

Interaction of HPV-18 and nitrosomethylurea in the induction of squamous cell carcinoma. Carcinogenesis (1993) 0.97

Growth and differentiation of human papillomavirus type 31b positive human cervical cell lines. Gynecol Oncol (1993) 0.96

DNA methylation analysis at distal and proximal promoter regions of the oestrogen receptor gene in breast cancers. Br J Cancer (1999) 0.93

Inhibition of skeletal metastasis by ectopic ERalpha expression in ERalpha-negative human breast cancer cell lines. Neoplasia (2007) 0.91

Multiple mechanisms of estrogen receptor gene repression contribute to ER-negative breast cancer. Pharmacogenomics J (2003) 0.88

Expression of estrogen receptors ERalpha and ERbeta in endometrial hyperplasia and adenocarcinoma. Int J Gynecol Cancer (2005) 0.87

Estrogen receptor, progesterone receptor, and bcl-2 are markers with prognostic significance in CIN III. Int J Gynecol Cancer (2004) 0.86

Estrogen receptor localization in normal and neoplastic epithelium of the uterine cervix. Cancer (1990) 0.85

Role of estrogens and their receptors in adhesion and invasiveness of breast cancer cells. Adv Exp Med Biol (2008) 0.85

Stable expression of the human estrogen receptor in HeLa cells by infection: effect of estrogen on cell proliferation and c-myc expression. Mol Cell Endocrinol (1991) 0.85

A DNA methylation pattern similar to normal tissue is associated with better prognosis in human cervical cancer. Cancer Lett (2004) 0.85

Assessment of hypermethylated DNA in two promoter regions of the estrogen receptor alpha gene in human endometrial diseases. Gynecol Oncol (2000) 0.82

Down regulation of estrogen receptor expression is an early event in human papillomavirus infected cervical dysplasia. Eur J Gynaecol Oncol (2005) 0.82

Differential response of cervical intraepithelial and cervical carcinoma cell lines to transforming growth factor-beta 1. Gynecol Oncol (1994) 0.80

Overexpression of estrogen receptor-alpha in the endometrial carcinoma cell line Ishikawa: inhibition of growth and angiogenic factors. Gynecol Oncol (2004) 0.80

DNA methylation of nuclear receptor genes--possible role in malignancy. J Steroid Biochem Mol Biol (2002) 0.79

Articles by these authors

Heterogeneity in cancer: cancer stem cells versus clonal evolution. Cell (2009) 7.09

p53-mediated activation of miRNA34 candidate tumor-suppressor genes. Curr Biol (2007) 6.87

The SLUG zinc-finger protein represses E-cadherin in breast cancer. Cancer Res (2002) 6.47

A Wnt-Axin2-GSK3beta cascade regulates Snail1 activity in breast cancer cells. Nat Cell Biol (2006) 4.55

Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth. Nature (2012) 4.41

MicroRNA miR-34 inhibits human pancreatic cancer tumor-initiating cells. PLoS One (2009) 3.66

Gene expression in ovarian cancer reflects both morphology and biological behavior, distinguishing clear cell from other poor-prognosis ovarian carcinomas. Cancer Res (2002) 3.62

The yeast DHHC cysteine-rich domain protein Akr1p is a palmitoyl transferase. J Cell Biol (2002) 3.48

Activation of AXIN2 expression by beta-catenin-T cell factor. A feedback repressor pathway regulating Wnt signaling. J Biol Chem (2002) 3.34

Wnt-dependent regulation of the E-cadherin repressor snail. J Biol Chem (2005) 3.03

Mouse model of human ovarian endometrioid adenocarcinoma based on somatic defects in the Wnt/beta-catenin and PI3K/Pten signaling pathways. Cancer Cell (2007) 3.02

Expression of miR-33 from an SREBP2 intron inhibits cholesterol export and fatty acid oxidation. J Biol Chem (2010) 2.99

Mouse model of colonic adenoma-carcinoma progression based on somatic Apc inactivation. Cancer Res (2007) 2.97

Transient activation of beta -catenin signaling in cutaneous keratinocytes is sufficient to trigger the active growth phase of the hair cycle in mice. Genes Dev (2003) 2.59

Activation of p38 mitogen-activated protein kinase in spinal microglia is a critical link in inflammation-induced spinal pain processing. J Neurochem (2003) 2.42

Cadherin and catenin alterations in human cancer. Genes Chromosomes Cancer (2002) 2.32

Human ovarian carcinoma–associated mesenchymal stem cells regulate cancer stem cells and tumorigenesis via altered BMP production. J Clin Invest (2011) 2.32

Derepression of ethylene-stabilized transcription factors (EIN3/EIL1) mediates jasmonate and ethylene signaling synergy in Arabidopsis. Proc Natl Acad Sci U S A (2011) 2.25

Survivin and molecular pathogenesis of colorectal cancer. Lancet (2003) 2.25

FGF-20 and DKK1 are transcriptional targets of beta-catenin and FGF-20 is implicated in cancer and development. EMBO J (2004) 2.24

A p53/miRNA-34 axis regulates Snail1-dependent cancer cell epithelial-mesenchymal transition. J Cell Biol (2011) 2.19

Fibroblast growth factor 9 has oncogenic activity and is a downstream target of Wnt signaling in ovarian endometrioid adenocarcinomas. Cancer Res (2006) 2.16

Proteomic markers of DNA repair and PI3K pathway activation predict response to the PARP inhibitor BMN 673 in small cell lung cancer. Clin Cancer Res (2013) 2.09

Oncogenic function of ATDC in pancreatic cancer through Wnt pathway activation and beta-catenin stabilization. Cancer Cell (2009) 2.04

Tight junction proteins claudin-3 and claudin-4 are frequently overexpressed in ovarian cancer but not in ovarian cystadenomas. Clin Cancer Res (2003) 2.01

Mesenchymal cells reactivate Snail1 expression to drive three-dimensional invasion programs. J Cell Biol (2009) 1.99

Comparison of seven methods for producing Affymetrix expression scores based on False Discovery Rates in disease profiling data. BMC Bioinformatics (2005) 1.96

Activation of FAK and Src are receptor-proximal events required for netrin signaling. Nat Neurosci (2004) 1.89

ITF-2, a downstream target of the Wnt/TCF pathway, is activated in human cancers with beta-catenin defects and promotes neoplastic transformation. Cancer Cell (2002) 1.86

Mutant KRAS promotes hyperplasia and alters differentiation in the colon epithelium but does not expand the presumptive stem cell pool. Gastroenterology (2011) 1.86

Remodeling of the extracellular matrix through overexpression of collagen VI contributes to cisplatin resistance in ovarian cancer cells. Cancer Cell (2003) 1.81

Roles for miRNA-378/378* in adipocyte gene expression and lipogenesis. Am J Physiol Endocrinol Metab (2010) 1.78

CTNNB1 mutations and overexpression of Wnt/beta-catenin target genes in WT1-mutant Wilms' tumors. Am J Pathol (2004) 1.72

Dephosphorylated SRp38 acts as a splicing repressor in response to heat shock. Nature (2004) 1.67

CDX2 regulates liver intestine-cadherin expression in normal and malignant colon epithelium and intestinal metaplasia. Gastroenterology (2002) 1.62

Gene expression analysis of preinvasive and invasive cervical squamous cell carcinomas identifies HOXC10 as a key mediator of invasion. Cancer Res (2007) 1.53

Medusa structure of the gene regulatory network: dominance of transcription factors in cancer subtype classification. Exp Biol Med (Maywood) (2011) 1.50

BMN 673, a novel and highly potent PARP1/2 inhibitor for the treatment of human cancers with DNA repair deficiency. Clin Cancer Res (2013) 1.47

Novel candidate targets of beta-catenin/T-cell factor signaling identified by gene expression profiling of ovarian endometrioid adenocarcinomas. Cancer Res (2003) 1.46

Dissecting transcription regulatory pathways through a new bacterial one-hybrid reporter system. Genome Res (2009) 1.41

Uptake, translocation, and remobilization of zinc absorbed at different growth stages by rice genotypes of different Zn densities. J Agric Food Chem (2010) 1.41

Role of the dependence receptor DCC in colorectal cancer pathogenesis. J Clin Oncol (2004) 1.40

In vivo fluorescence-based endoscopic detection of colon dysplasia in the mouse using a novel peptide probe. PLoS One (2011) 1.36

Analysis of differential BRAF(V600E) mutational status in high aggressive papillary thyroid microcarcinoma. Ann Surg Oncol (2008) 1.34

TIP49 regulates beta-catenin-mediated neoplastic transformation and T-cell factor target gene induction via effects on chromatin remodeling. Cancer Res (2003) 1.31

COMMD1 disrupts HIF-1alpha/beta dimerization and inhibits human tumor cell invasion. J Clin Invest (2010) 1.28

Phosphorylation of angiomotin by Lats1/2 kinases inhibits F-actin binding, cell migration, and angiogenesis. J Biol Chem (2013) 1.27

Analysis of promoter methylation in stool: a novel method for the detection of colorectal cancer. Clin Gastroenterol Hepatol (2005) 1.27

Cervical cancer. J Natl Compr Canc Netw (2013) 1.24

Expression of membrane type 1 matrix metalloproteinase is associated with cervical carcinoma progression and invasion. Cancer Res (2005) 1.23

Towards a holistic, yet gene-centered analysis of gene expression profiles: a case study of human lung cancers. J Biomed Biotechnol (2006) 1.22

Improving human micronutrient nutrition through biofortification in the soil-plant system: China as a case study. Environ Geochem Health (2007) 1.22

Colitis and cancer: a tale of inflammatory cells and their cytokines. J Clin Invest (2008) 1.21

Accurate molecular classification of human cancers based on gene expression using a simple classifier with a pathological tree-based framework. Am J Pathol (2003) 1.20

The core protein of glypican Dally-like determines its biphasic activity in wingless morphogen signaling. Dev Cell (2009) 1.17

Gene expression patterns in mismatch repair-deficient colorectal cancers highlight the potential therapeutic role of inhibitors of the phosphatidylinositol 3-kinase-AKT-mammalian target of rapamycin pathway. Clin Cancer Res (2009) 1.15

Comprehensive proteome analysis of ovarian cancers using liquid phase separation, mass mapping and tandem mass spectrometry: a strategy for identification of candidate cancer biomarkers. Proteomics (2004) 1.15

Role of beta-catenin/T-cell factor-regulated genes in ovarian endometrioid adenocarcinomas. Am J Pathol (2002) 1.14

Alleviation of gut inflammation by Cdx2/Pxr pathway in a mouse model of chemical colitis. PLoS One (2012) 1.14

Generating somatic mosaicism with a Cre recombinase-microsatellite sequence transgene. Nat Methods (2008) 1.14

Silencing of CDX2 expression in colon cancer via a dominant repression pathway. J Biol Chem (2003) 1.13

Molecular mechanisms of heavy metal hyperaccumulation and phytoremediation. J Trace Elem Med Biol (2005) 1.11

Lysine residues Lys-19 and Lys-49 of beta-catenin regulate its levels and function in T cell factor transcriptional activation and neoplastic transformation. J Biol Chem (2006) 1.11

Neurofibromin 1 (NF1) defects are common in human ovarian serous carcinomas and co-occur with TP53 mutations. Neoplasia (2008) 1.08

Substituting white rice with brown rice for 16 weeks does not substantially affect metabolic risk factors in middle-aged Chinese men and women with diabetes or a high risk for diabetes. J Nutr (2011) 1.08

Preclinical testing of PI3K/AKT/mTOR signaling inhibitors in a mouse model of ovarian endometrioid adenocarcinoma. Clin Cancer Res (2011) 1.07

Dicer-like (DCL) proteins in plants. Funct Integr Genomics (2009) 1.07

Cervical cancer. J Natl Compr Canc Netw (2010) 1.07

DRO1, a gene down-regulated by oncogenes, mediates growth inhibition in colon and pancreatic cancer cells. J Biol Chem (2004) 1.07

Rap1 stabilizes beta-catenin and enhances beta-catenin-dependent transcription and invasion in squamous cell carcinoma of the head and neck. Clin Cancer Res (2009) 1.07

Sox9 induction, ectopic Paneth cells, and mitotic spindle axis defects in mouse colon adenomatous epithelium arising from conditional biallelic Apc inactivation. Am J Pathol (2013) 1.07