Published in Br J Pharmacol on June 01, 2010
Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines for codeine therapy in the context of cytochrome P450 2D6 (CYP2D6) genotype. Clin Pharmacol Ther (2011) 3.09
Clinical Pharmacogenetics Implementation Consortium guidelines for cytochrome P450 2D6 genotype and codeine therapy: 2014 update. Clin Pharmacol Ther (2014) 1.84
Applications of CYP450 testing in the clinical setting. Mol Diagn Ther (2013) 1.08
The effects of CYP2D6 and CYP3A activities on the pharmacokinetics of immediate release oxycodone. Br J Pharmacol (2010) 1.06
Do CYP2D6 genotypes reflect oxycodone requirements for cancer patients treated for cancer pain? A cross-sectional multicentre study. Eur J Clin Pharmacol (2011) 0.96
Influences on the pharmacokinetics of oxycodone: a multicentre cross-sectional study in 439 adult cancer patients. Eur J Clin Pharmacol (2010) 0.90
Differences between opioids: pharmacological, experimental, clinical and economical perspectives. Br J Clin Pharmacol (2013) 0.88
The effect of CYP2D6 drug-drug interactions on hydrocodone effectiveness. Acad Emerg Med (2014) 0.86
CYP2D6 genotype dependent oxycodone metabolism in postoperative patients. PLoS One (2013) 0.86
Impact of cachexia on pharmacokinetic disposition of and clinical responses to oxycodone in cancer patients. Eur J Clin Pharmacol (2012) 0.86
Impact of genetic polymorphism on drug-drug interactions mediated by cytochromes: a general approach. AAPS J (2013) 0.84
Emerging therapies for patients with symptoms of opioid-induced bowel dysfunction. Drug Des Devel Ther (2015) 0.83
Prediction of Metabolic Interactions With Oxycodone via CYP2D6 and CYP3A Inhibition Using a Physiologically Based Pharmacokinetic Model. CPT Pharmacometrics Syst Pharmacol (2014) 0.83
Pharmacogenetics of analgesic drugs. Br J Pain (2013) 0.83
Life-threatening adverse events following therapeutic opioid administration in adults: is pharmacogenetic analysis useful? Pain Res Manag (2013) 0.80
Genetic determinants of fetal opiate exposure and risk of neonatal abstinence syndrome: Knowledge deficits and prospects for future research. Clin Pharmacol Ther (2015) 0.78
Opioid therapy pharmacogenomics for noncancer pain: efficacy, adverse events, and costs. Pain Res Treat (2013) 0.77
Interaction of oxycodone and voriconazole-a case series of patients with cancer pain supports the findings of randomised controlled studies with healthy subjects. Eur J Clin Pharmacol (2011) 0.77
Evaluating the safety and efficacy of dextromethorphan/quinidine in the treatment of pseudobulbar affect. Neuropsychiatr Dis Treat (2014) 0.76
Pharmacogenomic considerations in opioid analgesia. Pharmgenomics Pers Med (2012) 0.75
Population pharmacokinetics and analgesic potency of oxycodone. Br J Clin Pharmacol (2016) 0.75
Opioids Resistance in Chronic Pain Management. Curr Neuropharmacol (2017) 0.75
Effects of Short-Term Oxycodone Maintenance on Experimental Pain Responses in Physically Dependent Opioid Abusers. J Pain (2017) 0.75
Relationship between cytochrome P450 polymorphisms and prescribed medication in elderly haemodialysis patients. Springerplus (2016) 0.75
Genetic Testing for Opioid Pain Management: A Primer. Pain Ther (2017) 0.75
CYP2D6 phenotypes are associated with adverse outcomes related to opioid medications. Pharmgenomics Pers Med (2017) 0.75
Method for quantitative estimation of thermal thresholds in patients. J Neurol Neurosurg Psychiatry (1976) 4.13
Psychomotor function and psychoactive drugs. Br J Clin Pharmacol (1980) 3.57
Codeine intoxication associated with ultrarapid CYP2D6 metabolism. N Engl J Med (2004) 2.83
Pharmacokinetics and pharmacodynamics of oral oxycodone in healthy human subjects: role of circulating active metabolites. Clin Pharmacol Ther (2006) 1.98
Antinociception by spinal and systemic oxycodone: why does the route make a difference? In vitro and in vivo studies in rats. Anesthesiology (2006) 1.70
The lower limb flexion reflex in humans. Prog Neurobiol (2005) 1.67
Complicated pain management in a CYP450 2D6 poor metabolizer. Pain Pract (2007) 1.58
Opiate receptor binding affected differentially by opiates and opioid peptides. Eur J Pharmacol (1979) 1.45
The intrinsic antinociceptive effects of oxycodone appear to be kappa-opioid receptor mediated. Pain (1997) 1.42
Normal-release and controlled-release oxycodone: pharmacokinetics, pharmacodynamics, and controversy. Support Care Cancer (2002) 1.29
Quantitative contribution of CYP2D6 and CYP3A to oxycodone metabolism in human liver and intestinal microsomes. Drug Metab Dispos (2004) 1.25
Mu receptor binding of some commonly used opioids and their metabolites. Life Sci (1991) 1.25
The AmpliChip CYP450 test: cytochrome P450 2D6 genotype assessment and phenotype prediction. Pharmacogenomics J (2008) 1.23
Morphine and ibuprofen compared using the cold pressor test. Pain (1988) 1.22
Pharmacokinetic-pharmacodynamic relationships of controlled-release oxycodone. Clin Pharmacol Ther (1996) 1.22
Effects of blocking CYP2D6 on the pharmacokinetics and pharmacodynamics of oxycodone. Clin Pharmacol Ther (1998) 1.21
Attenuation of morphine-induced delirium in palliative care by substitution with infusion of oxycodone. J Pain Symptom Manage (1996) 1.16
Oxycodone induces overexpression of P-glycoprotein (ABCB1) and affects paclitaxel's tissue distribution in Sprague Dawley rats. J Pharm Sci (2007) 1.14
Interaction of cytochrome P450 3A inhibitors with P-glycoprotein. J Pharmacol Exp Ther (2002) 1.11
Studies of heat pain sensation in man: perception thresholds, rate of stimulus rise and reaction time. Pain (1990) 1.08
The hypoalgesic effect of oxycodone in human experimental pain models in relation to the CYP2D6 oxidation polymorphism. Basic Clin Pharmacol Toxicol (2009) 1.06
The effects of CYP2D6 and CYP3A activities on the pharmacokinetics of immediate release oxycodone. Br J Pharmacol (2010) 1.06
Inhibition by fluoxetine of cytochrome P450 2D6 activity. Clin Pharmacol Ther (1993) 1.04
Discriminative stimulus, reinforcing, physical dependence, and antinociceptive effects of oxycodone in mice, rats, and rhesus monkeys. Exp Clin Psychopharmacol (2004) 1.04
Oral administration of a low dose of midazolam (75 microg) as an in vivo probe for CYP3A activity. Eur J Clin Pharmacol (2004) 1.03
Activation of G-proteins by morphine and codeine congeners: insights to the relevance of O- and N-demethylated metabolites at mu- and delta-opioid receptors. J Pharmacol Exp Ther (2003) 1.00
Morphine, oxycodone, methadone and its enantiomers in different models of nociception in the rat. Anesth Analg (2006) 1.00
Comparison of epidural morphine and oxycodone for pain after abdominal surgery. J Clin Anesth (1997) 1.00
The influence of pharmacogenetics on opioid analgesia: studies with codeine and oxycodone in the Sprague-Dawley/Dark Agouti rat model. J Pharmacol Exp Ther (1994) 1.00
Voriconazole drastically increases exposure to oral oxycodone. Eur J Clin Pharmacol (2008) 0.98
Inhibition of UDP-glucuronosyltransferase 2b7-catalyzed morphine glucuronidation by ketoconazole: dual mechanisms involving a novel noncompetitive mode. Drug Metab Dispos (2006) 0.98
Oxycodone. Pharmacological profile and clinical data in chronic pain management. Minerva Anestesiol (2005) 0.96
Rifampin greatly reduces the plasma concentrations of intravenous and oral oxycodone. Anesthesiology (2009) 0.96
Adverse drug reactions to oxycodone and hydrocodone in CYP2D6 ultrarapid metabolizers. J Clin Psychopharmacol (2003) 0.92
Response to hydrocodone, codeine and oxycodone in a CYP2D6 poor metabolizer. Prog Neuropsychopharmacol Biol Psychiatry (2006) 0.92
Visual hallucination and tremor induced by sertraline and oxycodone in a bone marrow transplant patient. J Clin Pharmacol (2001) 0.85
Impact of CYP2C19 phenotypes on escitalopram metabolism and an evaluation of pupillometry as a serotonergic biomarker. Eur J Clin Pharmacol (2009) 0.84
[Genetic polymorphism and drug interactions: their importance in the treatment of pain]. Can J Anaesth (2005) 0.83
Oxymorphone metabolism and urinary excretion in human, rat, guinea pig, rabbit, and dog. Drug Metab Dispos (1983) 0.82
Oxycodone's mechanism of action and potency differences after spinal and systemic routes of administration. Anesthesiology (2007) 0.82
Development and validation of a chemical hydrolysis method for dextromethorphan and dextrophan determination in urine samples: application to the assessment of CYP2D6 activity in fibromyalgia patients. J Chromatogr B Analyt Technol Biomed Life Sci (2007) 0.82
Involvement of mu1-opioid receptor on oxycodone-induced antinociception in diabetic mice. Eur J Pharmacol (2007) 0.81
Pharmacogenetic determinants of codeine induction by rifampin: the impact on codeine's respiratory, psychomotor and miotic effects. J Pharmacol Exp Ther (1997) 0.80
Negative urine opioid screening caused by rifampin-mediated induction of oxycodone hepatic metabolism. Clin Chim Acta (2006) 0.79
The domain-specific probe EUB338 is insufficient for the detection of all Bacteria: development and evaluation of a more comprehensive probe set. Syst Appl Microbiol (1999) 11.01
In situ probing of gram-positive bacteria with high DNA G + C content using 23S rRNA-targeted oligonucleotides. Microbiology (1994) 6.36
Phylogeny of all recognized species of ammonia oxidizers based on comparative 16S rRNA and amoA sequence analysis: implications for molecular diversity surveys. Appl Environ Microbiol (2000) 5.12
Construction and characterization of a recombinant plasmid encoding the gene for the thymidine kinase of Herpes simplex type 1 virus. Gene (1979) 5.09
Combination of fluorescent in situ hybridization and microautoradiography-a new tool for structure-function analyses in microbial ecology. Appl Environ Microbiol (1999) 4.77
The focusing positions of polypeptides in immobilized pH gradients can be predicted from their amino acid sequences. Electrophoresis (1993) 4.64
Phylogenetic probes for analyzing abundance and spatial organization of nitrifying bacteria. Appl Environ Microbiol (1996) 4.59
Induction of direct antimicrobial activity through mammalian toll-like receptors. Science (2001) 4.46
Combined molecular and conventional analyses of nitrifying bacterium diversity in activated sludge: Nitrosococcus mobilis and Nitrospira-like bacteria as dominant populations. Appl Environ Microbiol (1998) 4.23
Genomewide association for schizophrenia in the CATIE study: results of stage 1. Mol Psychiatry (2008) 4.14
Cloning and mutagenesis of the murine gammaherpesvirus 68 genome as an infectious bacterial artificial chromosome. J Virol (2000) 4.09
Possible peptide chain termination mutants in thymide kinase gene of a mammalian virus, herpes simplex virus. Proc Natl Acad Sci U S A (1975) 4.00
Linkage mapping of autosomal dominant retinitis pigmentosa (RP1) to the pericentric region of human chromosome 8. Genomics (1991) 3.93
Choosing caesarean section. Lancet (2000) 3.67
Sum1 and Hst1 repress middle sporulation-specific gene expression during mitosis in Saccharomyces cerevisiae. EMBO J (1999) 3.65
Characterization of the multigene family encoding the mouse S16 ribosomal protein: strategy for distinguishing an expressed gene from its processed pseudogene counterparts by an analysis of total genomic DNA. Mol Cell Biol (1985) 3.48
Listeriosis: a resurgent foodborne infection. Clin Microbiol Infect (2010) 3.40
Molecular evidence for genus level diversity of bacteria capable of catalyzing anaerobic ammonium oxidation. Syst Appl Microbiol (2000) 3.36
A test statistic to detect errors in sib-pair relationships. Am J Hum Genet (1998) 3.28
In situ visualization of high genetic diversity in a natural microbial community. J Bacteriol (1996) 3.08
Risperidone versus clozapine in treatment-resistant chronic schizophrenia: a randomized double-blind study. The Risperidone Study Group. Am J Psychiatry (1998) 2.96
Identification and activities in situ of Nitrosospira and Nitrospira spp. as dominant populations in a nitrifying fluidized bed reactor. Appl Environ Microbiol (1998) 2.88
Practical considerations in design of internal amplification controls for diagnostic PCR assays. J Clin Microbiol (2004) 2.86
Gate-tuning of graphene plasmons revealed by infrared nano-imaging. Nature (2012) 2.75
A global witch-hunt. Lancet (1995) 2.69
Diversity of sulfate-reducing bacteria in oxic and anoxic regions of a microbial mat characterized by comparative analysis of dissimilatory sulfite reductase genes. Appl Environ Microbiol (1999) 2.55
In situ characterization of Nitrospira-like nitrite-oxidizing bacteria active in wastewater treatment plants. Appl Environ Microbiol (2001) 2.52
Neurophysiologic evidence for a central sensitization in patients with fibromyalgia. Arthritis Rheum (2003) 2.51
Commentary: the public health consequences of restricted induced abortion--lessons from Romania. Am J Public Health (1992) 2.44
Pancreatic fistula after pancreatic head resection. Br J Surg (2000) 2.44
High-versus low-dose erythropoietin in extremely low birth weight infants. The European Multicenter rhEPO Study Group. J Pediatr (1998) 2.41
Occult dysplasia is disclosed by Lugol chromoendoscopy in alcoholics at high risk for squamous cell carcinoma of the esophagus. Endoscopy (1999) 2.32
Activation of Ca2+ entry into acinar cells by a non-phosphorylatable inositol trisphosphate. Nature (1991) 2.30
NF-kappaB/Rel activation in cerulein pancreatitis. Gastroenterology (1999) 2.21
Detection and genotyping of human group A rotaviruses by oligonucleotide microarray hybridization. J Clin Microbiol (2002) 2.12
Can we talk? Inpatient discussions about advance directives in a community hospital. Attending physicians' attitudes, their inpatients' wishes, and reported experience. Arch Intern Med (1994) 2.09
Multiple lateral transfers of dissimilatory sulfite reductase genes between major lineages of sulfate-reducing prokaryotes. J Bacteriol (2001) 2.05
An integrated hospital information system in Geneva. MD Comput (1990) 2.04
Rosacea and Helicobacter pylori: interference of systemic antibiotic in the study of possible association. J Eur Acad Dermatol Venereol (2000) 2.04
Endosymbiotic sulphate-reducing and sulphide-oxidizing bacteria in an oligochaete worm. Nature (2001) 1.93
Fluorescent microsphere-based readout technology for multiplexed human single nucleotide polymorphism analysis and bacterial identification. Hum Mutat (2001) 1.89
Effect of preoperative biliary drainage on surgical outcome after pancreatoduodenectomy. Am J Surg (2001) 1.87
Compensating for heterogeneities in proton radiation therapy. Phys Med Biol (1984) 1.86
Subcortical correlates of craving in recently abstinent alcoholic patients. Am J Psychiatry (2001) 1.84
Hereditary multiple exostosis and chondrosarcoma: linkage to chromosome II and loss of heterozygosity for EXT-linked markers on chromosomes II and 8. Am J Hum Genet (1995) 1.82
In situ detection of novel bacterial endosymbionts of Acanthamoeba spp. phylogenetically related to members of the order Rickettsiales. Appl Environ Microbiol (1999) 1.81
Spatial specification of mammalian eye territories by reciprocal transcriptional repression of Pax2 and Pax6. Development (2000) 1.77
WNT5A--target of CUTL1 and potent modulator of tumor cell migration and invasion in pancreatic cancer. Carcinogenesis (2007) 1.76
Risk factors for incident mild cognitive impairment--results from the German Study on Ageing, Cognition and Dementia in Primary Care Patients (AgeCoDe). Acta Psychiatr Scand (2009) 1.76
Comparison of different approaches to quantify Staphylococcus aureus cells by real-time quantitative PCR and application of this technique for examination of cheese. Appl Environ Microbiol (2001) 1.76
Midwife-managed care. Lancet (1996) 1.75
Flow cytometric platform for high-throughput single nucleotide polymorphism analysis. Biotechniques (2001) 1.75
Unusual electronic effects of electron-withdrawing sulfonamide groups in optically and magnetically active self-assembled noncovalent heterodimetallic d-f podates. Inorg Chem (2000) 1.72
Misoprostol (Cytotec) for labor induction: a cautionary tale. Midwifery Today Int Midwife (1999) 1.72
Multimedia image and data navigation workstation. Radiographics (1997) 1.72
Controlled multicenter trial of laparoscopic transabdominal preperitoneal hernioplasty vs Shouldice herniorrhaphy. Early results. Surg Endosc (1996) 1.71
Clinical pharmacokinetics of the third generation cephalosporins. Clin Pharmacokinet (1985) 1.70
Analysis of DNA of defective herpes simplex virus type 1 by restriction endonuclease cleavage and nucleic acid hybridization. Cold Spring Harb Symp Quant Biol (1975) 1.69
Linear and nonlinear current density reconstructions. J Clin Neurophysiol (1999) 1.65
Impact of abdominal CT on the management of patients presenting to the emergency department with acute abdominal pain. AJR Am J Roentgenol (2000) 1.64
Community structure and activity dynamics of nitrifying bacteria in a phosphate-removing biofilm. Appl Environ Microbiol (2001) 1.63
Drug-drug interactions of new active substances: mibefradil example. Eur J Clin Pharmacol (1999) 1.63
Interaction of the yeast pleiotropic drug resistance genes PDR1 and PDR5. Curr Genet (1992) 1.62
Identification of some of the major groups of bacteria in efficient and nonefficient biological phosphorus removal activated sludge systems. Appl Environ Microbiol (1999) 1.62
Removing a barrier to computer-based outbreak and disease surveillance--the RODS Open Source Project. MMWR Morb Mortal Wkly Rep (2004) 1.60
Psychiatric disorders in patients with fibromyalgia. A multicenter investigation. Psychosomatics (1999) 1.60
Isolation and phylogenetic analysis of bacteria with antimicrobial activities from the Mediterranean sponges Aplysina aerophoba and Aplysina cavernicola. FEMS Microbiol Ecol (2001) 1.58
Pharmacogenetics-based population pharmacokinetic analysis of efavirenz in HIV-1-infected individuals. Clin Pharmacol Ther (2009) 1.57
Genome-wide association study of obsessive-compulsive disorder. Mol Psychiatry (2012) 1.57
Episiotomy: a form of genital mutilation. Lancet (1999) 1.57
Fluorescence in situ hybridization shows spatial distribution of as yet uncultured treponemes in biopsies from digital dermatitis lesions. Microbiology (1998) 1.55
Neochlamydia hartmannellae gen. nov., sp. nov. (Parachlamydiaceae), an endoparasite of the amoeba Hartmannella vermiformis. Microbiology (2000) 1.54
Electronic and plasmonic phenomena at graphene grain boundaries. Nat Nanotechnol (2013) 1.53
The multiple immune-evasion genes of murine cytomegalovirus are not redundant: m4 and m152 inhibit antigen presentation in a complementary and cooperative fashion. J Exp Med (2001) 1.52
The role of higher-order motor areas in voluntary movement as revealed by high-resolution EEG and fMRI. Neuroimage (1999) 1.51
Novel bacterial endosymbionts of Acanthamoeba spp. related to the Paramecium caudatum symbiont Caedibacter caryophilus. Environ Microbiol (1999) 1.50
Contribution of monoaminergic modulation to the analgesic effect of tramadol. Br J Clin Pharmacol (1996) 1.50
A nonlinear wide-range immobilized pH gradient for two-dimensional electrophoresis and its definition in a relevant pH scale. Electrophoresis (1993) 1.48
Laparoscopic versus open appendectomy for complicated appendicitis in high risk patients. Int J Colorectal Dis (2014) 1.47
Population pharmacokinetics of imatinib and the role of alpha-acid glycoprotein. Br J Clin Pharmacol (2006) 1.46
KIBRA gene variants are associated with episodic memory in healthy elderly. Neurobiol Aging (2007) 1.46
Impact of smoking, smoking cessation, and genetic polymorphisms on CYP1A2 activity and inducibility. Clin Pharmacol Ther (2011) 1.46
Potassium-angiotensin interplay in the regulation of aldosterone biosynthesis. Clin Endocrinol (Oxf) (1995) 1.46
Cultivation-independent, semiautomatic determination of absolute bacterial cell numbers in environmental samples by fluorescence in situ hybridization. Appl Environ Microbiol (2001) 1.46
Aggression and counteraggression during child psychiatric hospitalization. J Am Acad Child Adolesc Psychiatry (1990) 1.45
Mitochondrial responses to carbon monoxide toxicity. Ann N Y Acad Sci (1970) 1.45
16S-23S rDNA intergenic spacer and 23S rDNA of anaerobic ammonium-oxidizing bacteria: implications for phylogeny and in situ detection. Environ Microbiol (2001) 1.44
Cefoperazone: pharmacokinetics in humans with normal and impaired renal function and pharmacokinetics in rats. Clin Ther (1980) 1.44
Genetic evidence of an essential role for cytomegalovirus small capsid protein in viral growth. J Virol (2001) 1.43
Randomized clinical trial of pylorus-preserving duodenopancreatectomy versus classical Whipple resection-long term results. Br J Surg (2005) 1.42
[Current status of minimally invasive plate osteosynthesis: specific part II]. Unfallchirurg (2009) 1.42
Genome-wide association study of Tourette's syndrome. Mol Psychiatry (2012) 1.42
Single lateral locked screw plating of bicondylar tibial plateau fractures. Clin Orthop Relat Res (2005) 1.41
The abundance of Zoogloea ramigera in sewage treatment plants. Appl Environ Microbiol (1995) 1.41
Phylogenetic diversity among geographically dispersed Chlamydiales endosymbionts recovered from clinical and environmental isolates of Acanthamoeba spp. Appl Environ Microbiol (2000) 1.41
Preventing progression to first-episode psychosis in early initial prodromal states. Br J Psychiatry (2011) 1.40
Role of MT-MMPs and MMP-2 in pancreatic cancer progression. Int J Cancer (2000) 1.39
Improvement of cognitive functions in chronic schizophrenic patients by recombinant human erythropoietin. Mol Psychiatry (2006) 1.38
[Usefulness of Bispectral Index (BIS) monitoring for early detection of cerebral hypoperfusions]. Ann Fr Anesth Reanim (2013) 1.38