Published in Transplantation on August 27, 2010
Modulation of CD8+ T cell responses to AAV vectors with IgG-derived MHC class II epitopes. Mol Ther (2013) 0.84
The use of donor-derived veto cells in hematopoietic stem cell transplantation. Front Immunol (2012) 0.78
The role of donor-derived veto cells in nonmyeloablative haploidentical HSCT. Bone Marrow Transplant (2015) 0.75
The extracellular signal-regulated kinase: multiple substrates regulate diverse cellular functions. Growth Factors (2006) 5.58
Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation. Blood (2011) 4.57
The MEK/ERK cascade: from signaling specificity to diverse functions. Biochim Biophys Acta (2006) 4.06
Full haplotype-mismatched hematopoietic stem-cell transplantation: a phase II study in patients with acute leukemia at high risk of relapse. J Clin Oncol (2005) 3.81
Vimentin-dependent spatial translocation of an activated MAP kinase in injured nerve. Neuron (2005) 3.09
The MAP kinase signaling cascades: a system of hundreds of components regulates a diverse array of physiological functions. Methods Mol Biol (2010) 2.72
Cross-talk between Akt, p53 and Mdm2: possible implications for the regulation of apoptosis. Oncogene (2002) 2.50
DNA-independent PARP-1 activation by phosphorylated ERK2 increases Elk1 activity: a link to histone acetylation. Mol Cell (2007) 2.48
The ERK cascade: a prototype of MAPK signaling. Mol Biotechnol (2005) 2.45
Human embryonic stem cells and their differentiated derivatives are less susceptible to immune rejection than adult cells. Stem Cells (2005) 2.24
CXCL12 secretion by bone marrow stromal cells is dependent on cell contact and mediated by connexin-43 and connexin-45 gap junctions. Nat Immunol (2011) 2.05
The MAPK cascades: signaling components, nuclear roles and mechanisms of nuclear translocation. Biochim Biophys Acta (2010) 1.85
The ERK Cascade: Distinct Functions within Various Subcellular Organelles. Genes Cancer (2011) 1.74
Human and porcine early kidney precursors as a new source for transplantation. Nat Med (2002) 1.73
Identification and characterization of a general nuclear translocation signal in signaling proteins. Mol Cell (2008) 1.73
Interaction with MEK causes nuclear export and downregulation of peroxisome proliferator-activated receptor gamma. Mol Cell Biol (2006) 1.59
Isolation and characterization of nontubular sca-1+lin- multipotent stem/progenitor cells from adult mouse kidney. J Am Soc Nephrol (2006) 1.59
Vimentin binding to phosphorylated Erk sterically hinders enzymatic dephosphorylation of the kinase. J Mol Biol (2006) 1.57
Reconstruction of cell lineage trees in mice. PLoS One (2008) 1.46
The mitogen-activated protein kinase signaling cascade: from bench to bedside. Isr Med Assoc J (2002) 1.44
Haploidentical hematopoietic transplantation: current status and future perspectives. Blood (2011) 1.40
Multiple imprinted and stemness genes provide a link between normal and tumor progenitor cells of the developing human kidney. Cancer Res (2006) 1.39
Interactions of beta and gamma ENaC with Nedd4 can be facilitated by an ERK-mediated phosphorylation. J Biol Chem (2002) 1.37
MAPK kinases as nucleo-cytoplasmic shuttles for PPARgamma. Cell Cycle (2007) 1.37
The subcellular localization of MEK and ERK--a novel nuclear translocation signal (NTS) paves a way to the nucleus. Mol Cell Endocrinol (2009) 1.37
Atypical PKC-zeta regulates SDF-1-mediated migration and development of human CD34+ progenitor cells. J Clin Invest (2005) 1.36
Embryonic pig pancreatic tissue for the treatment of diabetes in a nonhuman primate model. Proc Natl Acad Sci U S A (2009) 1.32
ERK1c regulates Golgi fragmentation during mitosis. J Cell Biol (2006) 1.28
Protein-protein interactions in the regulation of the extracellular signal-regulated kinase. Mol Biotechnol (2005) 1.28
Direct imaging of immune rejection and memory induction by allogeneic mesenchymal stromal cells. Stem Cells (2009) 1.25
Activation of MAPK cascades by GnRH: ERK and Jun N-terminal kinase are involved in basal and GnRH-stimulated activity of the glycoprotein hormone LHbeta-subunit promoter. Endocrinology (2002) 1.20
Embryonic pig liver, pancreas, and lung as a source for transplantation: optimal organogenesis without teratoma depends on distinct time windows. Proc Natl Acad Sci U S A (2005) 1.19
Activation of AMP-activated protein kinase by human EGF receptor 2/EGF receptor tyrosine kinase inhibitor protects cardiac cells. Proc Natl Acad Sci U S A (2007) 1.18
Nuclear extracellular signal-regulated kinase 1 and 2 translocation is mediated by casein kinase 2 and accelerated by autophosphorylation. Mol Cell Biol (2011) 1.17
Mechanism of short-term ERK activation by electromagnetic fields at mobile phone frequencies. Biochem J (2007) 1.16
BMP-mediated inhibition of FGF signaling promotes cardiomyocyte differentiation of anterior heart field progenitors. Development (2010) 1.14
Embryonic pig pancreatic tissue transplantation for the treatment of diabetes. PLoS Med (2006) 1.14
Transplantation of human hematopoietic stem cells into ischemic and growing kidneys suggests a role in vasculogenesis but not tubulogenesis. Stem Cells (2006) 1.11
Design principles of cell circuits with paradoxical components. Proc Natl Acad Sci U S A (2012) 1.11
Overcoming T cell-mediated rejection of bone marrow allografts by T-regulatory cells: synergism with veto cells and rapamycin. Exp Hematol (2006) 1.11
A positive role of the PI3-K/Akt signaling pathway in PC12 cell differentiation. Mol Cells (2004) 1.11
The ERK signaling cascade--views from different subcellular compartments. Biofactors (2009) 1.11
Nanoscale increases in CD2-CD48-mediated intermembrane spacing decrease adhesion and reorganize the immunological synapse. J Biol Chem (2008) 1.09
Extracellular signal-regulated kinase 1c (ERK1c), a novel 42-kilodalton ERK, demonstrates unique modes of regulation, localization, and function. Mol Cell Biol (2004) 1.07
Extracellular signal-regulated kinase, Jun N-terminal kinase, p38, and c-Src are involved in gonadotropin-releasing hormone-stimulated activity of the glycoprotein hormone follicle-stimulating hormone beta-subunit promoter. Endocrinology (2004) 1.07
Estimating cell depth from somatic mutations. PLoS Comput Biol (2008) 1.06
Retracted Regulation of p53: intricate loops and delicate balances. Biochem Pharmacol (2002) 1.05
Retracted Calcium-mediated interactions regulate the subcellular localization of extracellular signal-regulated kinases. J Biol Chem (2008) 1.04
"Designed" grafts for HLA-haploidentical stem cell transplantation. Blood (2013) 1.03
PPARgamma and MEK Interactions in Cancer. PPAR Res (2008) 1.02
Wishbone identifies bifurcating developmental trajectories from single-cell data. Nat Biotechnol (2016) 1.02
Regulation of p53: intricate loops and delicate balances. Ann N Y Acad Sci (2002) 1.01
Glycolysis and glucose transporter 1 as markers of response to hormonal therapy in breast cancer. Int J Cancer (2003) 1.00
Casein kinase 2 specifically binds to and phosphorylates the carboxy termini of ENaC subunits. Eur J Biochem (2002) 1.00
Deletion of cognate CD8 T cells by immature dendritic cells: a novel role for perforin, granzyme A, TREM-1, and TLR7. Blood (2012) 0.99
Calcium regulates ERK signaling by modulating its protein-protein interactions. Commun Integr Biol (2008) 0.99
Phosphomimetic mutants of pigment epithelium-derived factor with enhanced antiangiogenic activity as potent anticancer agents. Cancer Res (2010) 0.98
Manipulation of redox signaling in mammalian cells enabled by controlled photogeneration of reactive oxygen species. J Cell Sci (2005) 0.97
Immunoselection and clinical use of T regulatory cells in HLA-haploidentical stem cell transplantation. Best Pract Res Clin Haematol (2011) 0.97
Down-regulation of steroidogenic response to gonadotropins in human and rat preovulatory granulosa cells involves mitogen-activated protein kinase activation and modulation of DAX-1 and steroidogenic factor-1. J Clin Endocrinol Metab (2003) 0.94
Activation of mitogen-activated protein kinase (MAPK) by GnRH is cell-context dependent. Mol Cell Endocrinol (2006) 0.94
Correction of hemophilia as a proof of concept for treatment of monogenic diseases by fetal spleen transplantation. Proc Natl Acad Sci U S A (2006) 0.94
The ERK cascade as a prototype of MAPK signaling pathways. Methods Mol Biol (2004) 0.94
ERK as a model for systems biology of enzyme kinetics in cells. Curr Biol (2013) 0.94
Tolerance induction by third-party "off-the-shelf" CD4+CD25+ Treg cells. Exp Hematol (2006) 0.93
Identification of extracellular signal-regulated kinase 1/2 and p38 MAPK as regulators of human sperm motility and acrosome reaction and as predictors of poor spermatozoan quality. J Biol Chem (2008) 0.93
Engraftment and differentiation of human metanephroi into functional mature nephrons after transplantation into mice is accompanied by a profile of gene expression similar to normal human kidney development. J Am Soc Nephrol (2002) 0.93
MEK5 and ERK5 are localized in the nuclei of resting as well as stimulated cells, while MEKK2 translocates from the cytosol to the nucleus upon stimulation. J Cell Sci (2004) 0.93
Extracellular phosphorylation converts pigment epithelium-derived factor from a neurotrophic to an antiangiogenic factor. Blood (2004) 0.92
Retracted c-Src is activated by the epidermal growth factor receptor in a pathway that mediates JNK and ERK activation by gonadotropin-releasing hormone in COS7 cells. J Biol Chem (2003) 0.91
A novel role for factor VIII and thrombin/PAR1 in regulating hematopoiesis and its interplay with the bone structure. Blood (2013) 0.91
Retracted Pigment epithelium-derived factor and its phosphomimetic mutant induce JNK-dependent apoptosis and p38-mediated migration arrest. J Biol Chem (2010) 0.91
The haploidentical option for high-risk haematological malignancies. Blood Cells Mol Dis (2007) 0.90
Tolerance induction by veto CTLs in the TCR transgenic 2C mouse model. II. Deletion of effector cells by Fas-Fas ligand apoptosis. J Immunol (2004) 0.90
Specific phosphorylation and activation of ERK1c by MEK1b: a unique route in the ERK cascade. Genes Dev (2009) 0.90
Embryonic porcine liver as a source for transplantation: advantage of intact liver implants over isolated hepatoblasts in overcoming homeostatic inhibition by the quiescent host liver. Stem Cells (2008) 0.90
Tolerance induction by megadose hematopoietic progenitor cells: expansion of veto cells by short-term culture of purified human CD34(+) cells. Blood (2002) 0.90
The Ras inhibitors caveolin-1 and docking protein 1 activate peroxisome proliferator-activated receptor γ through spatial relocalization at helix 7 of its ligand-binding domain. Mol Cell Biol (2011) 0.89
A preformed signaling complex mediates GnRH-activated ERK phosphorylation of paxillin and FAK at focal adhesions in L beta T2 gonadotrope cells. Mol Endocrinol (2009) 0.89
Tolerance induction by veto CTLs in the TCR transgenic 2C mouse model. I. Relative reactivity of different veto cells. J Immunol (2004) 0.89
Extracellular signal-regulated kinase and c-Src, but not Jun N-terminal kinase, are involved in basal and gonadotropin-releasing hormone-stimulated activity of the glycoprotein hormone alpha-subunit promoter. Endocrinology (2003) 0.87
CTLs respond with activation and granule secretion when serving as targets for T-cell recognition. Blood (2010) 0.87
Differential role of PKC isoforms in GnRH and phorbol 12-myristate 13-acetate activation of extracellular signal-regulated kinase and Jun N-terminal kinase. Endocrinology (2010) 0.87
Immune regulatory activity of CD34+ progenitor cells: evidence for a deletion-based mechanism mediated by TNF-alpha. Blood (2004) 0.87
Induction of tolerance to bone marrow allografts by donor-derived host nonreactive ex vivo-induced central memory CD8 T cells. Blood (2009) 0.85
Distinct pathways for the involvement of WNK4 in the signaling of hypertonicity and EGF. FEBS J (2008) 0.85
Transplants across human leukocyte antigen barriers. Semin Hematol (2002) 0.85