The role of endothelium and endogenous vasoactive substances in sepsis.

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Published in Hippokratia on April 01, 2010

Authors

G Kotsovolis, K Kallaras

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2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference. Crit Care Med (2003) 28.68

A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature (1988) 27.60

Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide. Proc Natl Acad Sci U S A (1987) 14.22

Nitric oxide: an endogenous modulator of leukocyte adhesion. Proc Natl Acad Sci U S A (1991) 8.04

Pathogenetic mechanisms of septic shock. N Engl J Med (1993) 6.64

Modulation of endothelial cell hemostatic properties by tumor necrosis factor. J Exp Med (1986) 6.32

The role of the endothelium in severe sepsis and multiple organ dysfunction syndrome. Blood (2003) 5.22

Septic shock in humans. Advances in the understanding of pathogenesis, cardiovascular dysfunction, and therapy. Ann Intern Med (1990) 5.15

Regulation of biosynthesis of nitric oxide. J Biol Chem (1994) 4.82

Apoptosis and caspases regulate death and inflammation in sepsis. Nat Rev Immunol (2006) 4.82

Endothelins: molecular biology, biochemistry, pharmacology, physiology, and pathophysiology. Pharmacol Rev (1994) 4.19

The role of nitric oxide and cGMP in platelet adhesion to vascular endothelium. Biochem Biophys Res Commun (1987) 3.25

Mechanisms of apoptosis. Am J Pathol (2000) 3.23

Loss of vascular responsiveness induced by endotoxin involves L-arginine pathway. Am J Physiol (1990) 2.83

Comparable increase of B-type natriuretic peptide and amino-terminal pro-B-type natriuretic peptide levels in patients with severe sepsis, septic shock, and acute heart failure. Crit Care Med (2006) 2.77

Signal transduction mechanisms involving nitric oxide. Biochem Pharmacol (1991) 2.72

Prognostic values of B-type natriuretic peptide in severe sepsis and septic shock. Crit Care Med (2007) 2.70

Predictive value of N-terminal pro-brain natriuretic peptide in severe sepsis and septic shock. Crit Care Med (2007) 2.44

Nitric oxide, an endothelial cell relaxation factor, inhibits neutrophil superoxide anion production via a direct action on the NADPH oxidase. J Clin Invest (1992) 2.14

Brain natriuretic peptide: A marker of myocardial dysfunction and prognosis during severe sepsis. Crit Care Med (2004) 2.05

NH2 terminal pro-brain natriuretic peptide plasma level as an early marker of prognosis and cardiac dysfunction in septic shock patients. Crit Care Med (2005) 1.85

Spatial relationships in early signaling events of flow-mediated endothelial mechanotransduction. Annu Rev Physiol (1997) 1.81

Clinical review: Myocardial depression in sepsis and septic shock. Crit Care (2002) 1.74

Epidemiology of severe sepsis around the world. Endocr Metab Immune Disord Drug Targets (2006) 1.63

Plasma level of N terminal pro-brain natriuretic peptide as a prognostic marker in critically ill patients. Anesth Analg (2006) 1.59

Plasma-induced endothelial oxidative stress is related to the severity of septic shock. Crit Care Med (2007) 1.57

Role of nitric oxide and cGMP in human septic serum-induced depression of cardiac myocyte contractility. Am J Physiol (1999) 1.55

Administration of the nitric oxide synthase inhibitor NG-methyl-L-arginine hydrochloride (546C88) by intravenous infusion for up to 72 hours can promote the resolution of shock in patients with severe sepsis: results of a randomized, double-blind, placebo-controlled multicenter study (study no. 144-002). Crit Care Med (2004) 1.51

Endothelial injury and regeneration. IV. Endotoxin: a nondenuding injury to aortic endothelium. Lab Invest (1983) 1.50

Relationship between B-type natriuretic peptides and pulmonary capillary wedge pressure in the intensive care unit. J Am Coll Cardiol (2005) 1.45

Left ventricular systolic and diastolic function in septic shock. Intensive Care Med (1997) 1.45

Functional heterogeneity of vascular endothelial cells. Biochem Pharmacol (1987) 1.34

Gene expression of brain natriuretic peptide in isolated atrial and ventricular human myocardium: influence of angiotensin II and diastolic fiber length. Circulation (2000) 1.31

Extravascular lung water to blood volume ratios as measures of permeability in sepsis-induced ALI/ARDS. Intensive Care Med (2006) 1.25

Plasma atrial natriuretic peptide and brain natriuretic peptide are increased in septic shock: impact of interleukin-6 and sepsis-associated left ventricular dysfunction. Intensive Care Med (2003) 1.25

Physiology of the endothelium. Br J Anaesth (2004) 1.25

Cardiovascular effects of the nitric oxide synthase inhibitor NG-methyl-L-arginine hydrochloride (546C88) in patients with septic shock: results of a randomized, double-blind, placebo-controlled multicenter study (study no. 144-002). Crit Care Med (2004) 1.24

Natriuretic peptides as cardiac hormones in normotensive and spontaneously hypertensive rats. The ventricle is a major site of synthesis and secretion of brain natriuretic peptide. Circ Res (1991) 1.23

The role of nitric oxide in sepsis--an overview. Acta Anaesthesiol Scand (1999) 1.23

Nitric oxide and cardiovascular control. Exp Physiol (1993) 1.21

Bench-to-bedside review: endothelial cell dysfunction in severe sepsis: a role in organ dysfunction? Crit Care (2003) 1.18

The microcirculation during endotoxemia. Cardiovasc Res (1996) 1.16

Elevated plasma endothelin-1 concentrations are associated with the severity of illness in patients with sepsis. Ann Surg (1991) 1.12

The role of high mobility group box-1 protein in severe sepsis. Curr Opin Infect Dis (2006) 1.11

B-type natriuretic peptide and weaning from mechanical ventilation. Intensive Care Med (2006) 1.10

Natriuretic peptide testing for the evaluation of critically ill patients with shock in the intensive care unit: a prospective cohort study. Crit Care (2006) 1.10

Induction of NG-monomethyl-L-arginine uptake: a mechanism for differential inhibition of NO synthases? Am J Physiol (1995) 1.07

C-type natriuretic peptide: the endothelial component of the natriuretic peptide system. J Cardiovasc Pharmacol (1998) 1.03

Science review: natriuretic peptides in critical illness. Crit Care (2004) 1.03

The endothelin system in septic and endotoxin shock. Eur J Pharmacol (2000) 1.02

Fluid therapy in sepsis with capillary leakage. Eur J Anaesthesiol (2003) 1.01

Nitric oxide in sepsis and endotoxaemia. J Antimicrob Chemother (1998) 1.00

Endotoxin, interleukin-1, and tumor necrosis factor cause neutrophil-dependent microvascular leakage in postcapillary venules. Am J Pathol (1992) 1.00

Fibrinolytic system of vascular endothelial cells. Role of plasminogen activator inhibitors. Haemostasis (1988) 0.99

Synergistic effects of tumor necrosis factor-alpha and thrombin in increasing endothelial permeability. Am J Physiol Lung Cell Mol Physiol (2001) 0.98

Lipopolysaccharide depresses cardiac contractility and beta-adrenergic contractile response by decreasing myofilament response to Ca2+ in cardiac myocytes. Circ Res (1997) 0.97

Endotoxemia causes central downregulation of sympathetic vasomotor tone in healthy humans. Am J Physiol Regul Integr Comp Physiol (2008) 0.96

Endothelial cells: role in infection and inflammation. World J Surg (1998) 0.93

B-type natriuretic peptide: issues for the intensivist and pulmonologist. Crit Care Med (2005) 0.90

Endogenous and exogenous catecholamines in critical care medicine. Crit Care Med (1982) 0.89

Brain Natriuretic Peptide (BNP) regulates the production of inflammatory mediators in human THP-1 macrophages. Regul Pept (2008) 0.87

Sepsis: emerging role of nitric oxide and selectins. Clinics (Sao Paulo) (2006) 0.85

Plasma endothelin levels are increased during septic shock. Crit Care Med (1992) 0.83

Prostacyclin in sepsis: a systematic review. Prostaglandins Other Lipid Mediat (2006) 0.83

Modulation of endotoxin-induced endothelial function by calcium/calmodulin-dependent protein kinase. Shock (2003) 0.82

Effects of the endothelin receptor antagonist bosentan on cardiac performance during porcine endotoxin shock. Acta Anaesthesiol Scand (2001) 0.81

Increased plasma levels of NT-proANP and NT-proBNP as markers of cardiac dysfunction in septic patients. Clin Lab (2005) 0.81

Endothelin(A)-receptor antagonism attenuates pulmonary hypertension in porcine endotoxin shock. Eur Respir J (1999) 0.81

Hemodynamic response to fluid repletion in patients with septic shock: evidence for early depression of cardiac performance. Circ Shock (1987) 0.79

Differentiated effects on splanchnic homeostasis by selective and non-selective endothelin receptor antagonism in porcine endotoxaemia. Br J Pharmacol (1999) 0.79

Endothelial dysfunction and activation as an expression of disease: role of prostacyclin analogs. Int Immunopharmacol (2005) 0.78

[Molecular cloning of human endothelin receptors and their expression in vascular endothelial cells and smooth muscle cells]. Jpn Circ J (1992) 0.76

Role of endothelin in acute renal failure. Blood Purif (1997) 0.76

Effects of endothelin on hemodynamics, prostaglandins, blood coagulation and renal function. Kidney Int (1995) 0.76

Severe septic inflammation as a strong stimulus of myocardial NT-pro brain natriuretic peptide release. Int J Cardiol (2007) 0.76

Evolution of B-type natriuretic peptide in evaluation of intensive care unit shock. Crit Care Med (2004) 0.76

Predictive value of N-terminal pro-brain natriuretic peptide in sepsis. Crit Care Med (2007) 0.76