Published in Org Lett on August 06, 2010
An authentic imaging probe to track cell fate from beginning to end. Nat Commun (2014) 1.41
Biomarkers and molecular probes for cell death imaging and targeted therapeutics. Bioconjug Chem (2012) 1.10
Exploring theranostic potentials of radioiodinated hypericin in rodent necrosis models. Theranostics (2012) 0.95
Small Molecule Sequential Dual-Targeting Theragnostic Strategy (SMSDTTS): from Preclinical Experiments towards Possible Clinical Anticancer Applications. J Cancer (2013) 0.85
Targeting extracellular DNA to deliver IGF-1 to the injured heart. Sci Rep (2014) 0.81
Discovery of Radioiodinated Monomeric Anthraquinones as a Novel Class of Necrosis Avid Agents for Early Imaging of Necrotic Myocardium. Sci Rep (2016) 0.79
Developing injectable nanomaterials to repair the heart. Curr Opin Biotechnol (2015) 0.77
Oxidative condensations to form benzimidazole-substituted potassium organotrifluoroborates. Org Lett (2012) 0.77
H-gemcitabine: a new gemcitabine prodrug for treating cancer. Bioconjug Chem (2012) 0.76
Novel (18)F-Labeled 1-Hydroxyanthraquinone Derivatives for Necrotic Myocardium Imaging. ACS Med Chem Lett (2016) 0.75
Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med (2001) 51.99
DNA fragments in the blood plasma of cancer patients: quantitations and evidence for their origin from apoptotic and necrotic cells. Cancer Res (2001) 5.45
The roles of therapy-induced autophagy and necrosis in cancer treatment. Clin Cancer Res (2007) 3.35
Comparative evaluation of several DNA binding dyes in the detection of apoptosis-associated chromatin degradation by flow cytometry. Cytometry (1992) 2.30
DNA minor-groove recognition by small molecules. Nat Prod Rep (2001) 2.11
Binding characteristics of Hoechst 33258 with calf thymus DNA, poly[d(A-T)], and d(CCGGAATTCCGG): multiple stoichiometries and determination of tight binding with a wide spectrum of site affinities. Biochemistry (1990) 1.61
Role of C5a in multiorgan failure during sepsis. J Immunol (2001) 1.53
Apoptosis and efferocytosis in mouse models of atherosclerosis. Curr Drug Targets (2007) 1.50
Extracellular nucleic acids. Bioessays (2007) 1.29
Monofunctional near-infrared fluorochromes for imaging applications. Bioconjug Chem (2005) 1.23
Proteolytic mechanisms in necrotic cell death and neurodegeneration. FEBS Lett (2005) 1.06
Hoechst 33258 Tethered by a Hexa(ethylene glycol) Linker to the 5'-Termini of Oligodeoxynucleotide 15-Mers: Duplex Stabilization and Fluorescence Properties. J Org Chem (1997) 1.06
Noncovalent interactions with DNA: an overview. Mutat Res (2007) 1.04
A DNA-binding Gd chelate for the detection of cell death by MRI. Chem Commun (Camb) (2009) 1.02
Reaching into the major groove of B-DNA: synthesis and nucleic acid binding of a neomycin-hoechst 33258 conjugate. J Am Chem Soc (2003) 0.99
Label-free detection of protein-protein interactions on biochips. Angew Chem Int Ed Engl (2005) 0.95
A comparative study of the photosensitizing characteristics of some cyanine dyes. J Photochem Photobiol B (2000) 0.94
Cell-free DNA resuscitated for tumor testing. Nat Med (2008) 0.92
Hypoxia leads to necrotic hepatocyte death. J Biomed Mater Res A (2007) 0.89
The origin of extracellular DNA during the clearance of dead and dying cells. Autoimmunity (2007) 0.88
In vivo dynamic imaging of myocardial cell death using 99mTc-labeled C2A domain of synaptotagmin I in a rat model of ischemia and reperfusion. Nucl Med Biol (2007) 0.86
Phase I-II study of pibenzimol hydrochloride (NSC 322921) in advanced pancreatic carcinoma. Invest New Drugs (1991) 0.86
Phase II study of pibenzimol in pancreatic cancer. A Southwest Oncology Group study. Invest New Drugs (1991) 0.81
Solid-phase synthesis of positively charged deoxynucleic guanidine (DNG) tethering a Hoechst 33258 analogue: triplex and duplex stabilization by simultaneous minor groove binding. J Am Chem Soc (2004) 0.80
Determination of nucleic acids with a near infrared cyanine dye using resonance light scattering technique. Spectrochim Acta A Mol Biomol Spectrosc (2006) 0.78
Cognitive enhancers as adjuncts to psychotherapy: use of D-cycloserine in phobic individuals to facilitate extinction of fear. Arch Gen Psychiatry (2004) 5.26
Programming the magnitude and persistence of antibody responses with innate immunity. Nature (2011) 5.18
Short term outcomes of prostate biopsy in men tested for cancer by prostate specific antigen: prospective evaluation within ProtecT study. BMJ (2012) 4.64
Behavioral and neural analysis of extinction. Neuron (2002) 4.53
Facilitation of conditioned fear extinction by systemic administration or intra-amygdala infusions of D-cycloserine as assessed with fear-potentiated startle in rats. J Neurosci (2002) 4.52
A randomized, double-blind evaluation of D-cycloserine or alprazolam combined with virtual reality exposure therapy for posttraumatic stress disorder in Iraq and Afghanistan War veterans. Am J Psychiatry (2014) 4.25
Role of the bed nucleus of the stria terminalis versus the amygdala in fear, stress, and anxiety. Eur J Pharmacol (2003) 4.08
Toll-like receptor-mediated induction of type I interferon in plasmacytoid dendritic cells requires the rapamycin-sensitive PI(3)K-mTOR-p70S6K pathway. Nat Immunol (2008) 3.43
Different mechanisms of fear extinction dependent on length of time since fear acquisition. Learn Mem (2006) 3.30
Dissolving polymer microneedle patches for influenza vaccination. Nat Med (2010) 3.24
Applying learning principles to the treatment of post-trauma reactions. Ann N Y Acad Sci (2003) 3.05
Genetic correction of PSA values using sequence variants associated with PSA levels. Sci Transl Med (2010) 2.83
Brain-derived neurotrophic factor and tyrosine kinase receptor B involvement in amygdala-dependent fear conditioning. J Neurosci (2004) 2.73
Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis. Nat Genet (2013) 2.60
Characterization of Bouveret's syndrome: a comprehensive review of 128 cases. Am J Gastroenterol (2006) 2.58
A significant decline in the American domination of research in gastroenterology with increasing globalization from 1980 to 2005: an analysis of American authorship among 8,251 articles. Am J Gastroenterol (2008) 2.53
Emotion, motivation, and the brain: reflex foundations in animal and human research. Prog Brain Res (2006) 2.52
Impaired fear inhibition is a biomarker of PTSD but not depression. Depress Anxiety (2010) 2.27
The T helper type 2 response to cysteine proteases requires dendritic cell-basophil cooperation via ROS-mediated signaling. Nat Immunol (2010) 2.20
Amygdala BDNF signaling is required for consolidation but not encoding of extinction. Nat Neurosci (2006) 2.10
Regulation of synaptic plasticity genes during consolidation of fear conditioning. J Neurosci (2002) 2.10
Sustained release of a p38 inhibitor from non-inflammatory microspheres inhibits cardiac dysfunction. Nat Mater (2008) 2.05
In vivo imaging of hydrogen peroxide with chemiluminescent nanoparticles. Nat Mater (2007) 1.99
Role of the extended amygdala in short-duration versus sustained fear: a tribute to Dr. Lennart Heimer. Brain Struct Funct (2008) 1.97
Enhancing cannabinoid neurotransmission augments the extinction of conditioned fear. Neuropsychopharmacology (2005) 1.89
The role of amygdala glutamate receptors in fear learning, fear-potentiated startle, and extinction. Pharmacol Biochem Behav (2002) 1.87
Conditioned fear extinction and reinstatement in a human fear-potentiated startle paradigm. Learn Mem (2006) 1.78
Posttraumatic stress disorder may be associated with impaired fear inhibition: relation to symptom severity. Psychiatry Res (2009) 1.76
Regulation of gephyrin and GABAA receptor binding within the amygdala after fear acquisition and extinction. J Neurosci (2005) 1.72
Hydrocyanines: a class of fluorescent sensors that can image reactive oxygen species in cell culture, tissue, and in vivo. Angew Chem Int Ed Engl (2009) 1.69
Conditioned pharmacotherapeutic effects: a preliminary study. Psychosom Med (2009) 1.68
Orally delivered thioketal nanoparticles loaded with TNF-α-siRNA target inflammation and inhibit gene expression in the intestines. Nat Mater (2010) 1.67
Alterations in diurnal cortisol rhythm and acoustic startle response in nonhuman primates with adverse rearing. Biol Psychiatry (2005) 1.65
Annexin A1, formyl peptide receptor, and NOX1 orchestrate epithelial repair. J Clin Invest (2012) 1.57
Long-term therapy with aerosolized ribavirin for parainfluenza 3 virus respiratory tract infection in an infant with severe combined immunodeficiency. Pediatr Transplant (2007) 1.54
Differential regulation of brain-derived neurotrophic factor transcripts during the consolidation of fear learning. Learn Mem (2004) 1.53
Impaired safety signal learning may be a biomarker of PTSD. Neuropharmacology (2011) 1.52
Polyketal nanoparticles: a new pH-sensitive biodegradable drug delivery vehicle. Bioconjug Chem (2005) 1.52
Glutamate receptors in extinction and extinction-based therapies for psychiatric illness. Neuropsychopharmacology (2010) 1.51
Loss of extracellular superoxide dismutase leads to acute lung damage in the presence of ambient air: a potential mechanism underlying adult respiratory distress syndrome. Am J Pathol (2008) 1.51
Super pH-sensitive multifunctional polymeric micelle for tumor pH(e) specific TAT exposure and multidrug resistance. J Control Release (2008) 1.50
Fear potentiation and fear inhibition in a human fear-potentiated startle paradigm. Biol Psychiatry (2005) 1.49
Minimally invasive protein delivery with rapidly dissolving polymer microneedles. Adv Mater (2008) 1.49
Development of a new method for monitoring prostate-specific antigen changes in men with localised prostate cancer: a comparison of observational cohorts. Eur Urol (2009) 1.49
Timing of extinction relative to acquisition: a parametric analysis of fear extinction in humans. Behav Neurosci (2008) 1.45
Lactobacillus rhamnosus blocks inflammatory signaling in vivo via reactive oxygen species generation. Free Radic Biol Med (2009) 1.45
Height and prostate cancer risk: a large nested case-control study (ProtecT) and meta-analysis. Cancer Epidemiol Biomarkers Prev (2008) 1.44
Maleimide cross-linked bioactive PEG hydrogel exhibits improved reaction kinetics and cross-linking for cell encapsulation and in situ delivery. Adv Mater (2011) 1.43
Folate receptor-targeted antioxidant therapy ameliorates renal ischemia-reperfusion injury. J Am Soc Nephrol (2012) 1.41
"Hidden" social networks in behavior change interventions. Am J Public Health (2015) 1.41
Circulating folate, vitamin B12, homocysteine, vitamin B12 transport proteins, and risk of prostate cancer: a case-control study, systematic review, and meta-analysis. Cancer Epidemiol Biomarkers Prev (2010) 1.40
A new pH-responsive and glutathione-reactive, endosomal membrane-disruptive polymeric carrier for intracellular delivery of biomolecular drugs. J Control Release (2003) 1.39
Early intervention may prevent the development of posttraumatic stress disorder: a randomized pilot civilian study with modified prolonged exposure. Biol Psychiatry (2012) 1.37
Learning-dependent structural plasticity in the adult olfactory pathway. J Neurosci (2008) 1.34
Brain-derived neurotrophic factor in amygdala-dependent learning. Neuroscientist (2005) 1.31
Maltodextrin-based imaging probes detect bacteria in vivo with high sensitivity and specificity. Nat Mater (2011) 1.30
Contingency awareness and fear inhibition in a human fear-potentiated startle paradigm. Behav Neurosci (2006) 1.30
The effect of gonadal hormones and gender on anxiety and emotional learning. Horm Behav (2006) 1.29
The Australian Intervention Randomized Control of Rate in Atrial Fibrillation Trial (AIRCRAFT). J Am Coll Cardiol (2003) 1.29
Glutamate receptor antagonist infusions into the basolateral and medial amygdala reveal differential contributions to olfactory vs. context fear conditioning and expression. Learn Mem (2005) 1.28
Enteric commensal bacteria potentiate epithelial restitution via reactive oxygen species-mediated inactivation of focal adhesion kinase phosphatases. Proc Natl Acad Sci U S A (2011) 1.28
AX+, BX- discrimination learning in the fear-potentiated startle paradigm: possible relevance to inhibitory fear learning in extinction. Learn Mem (2004) 1.24
Temporary disruption of fear-potentiated startle following PKMζ inhibition in the amygdala. Nat Neurosci (2011) 1.23
Light-enhanced startle: further pharmacological and behavioral characterization. Psychopharmacology (Berl) (2001) 1.21
Involvement of central amygdalar and bed nucleus of the stria terminalis corticotropin-releasing factor in behavioral responses to social defeat. Behav Neurosci (2004) 1.20
Relationship of enhanced norepinephrine activity during memory consolidation to enhanced long-term memory in humans. Am J Psychiatry (2002) 1.18
Physicochemical characteristics of pH-sensitive poly(L-histidine)-b-poly(ethylene glycol)/poly(L-lactide)-b-poly(ethylene glycol) mixed micelles. J Control Release (2007) 1.18
Association of folate-pathway gene polymorphisms with the risk of prostate cancer: a population-based nested case-control study, systematic review, and meta-analysis. Cancer Epidemiol Biomarkers Prev (2009) 1.18
Olfactory-mediated fear-potentiated startle. Behav Neurosci (2002) 1.18
Daily living with distress and enrichment: the moral experience of families with ventilator-assisted children at home. Pediatrics (2006) 1.17
Quantifying fear potentiated startle using absolute versus proportional increase scoring methods: implications for the neurocircuitry of fear and anxiety. Psychopharmacology (Berl) (2002) 1.16
Effects of the beta-blocker propranolol on cued and contextual fear conditioning in humans. Psychopharmacology (Berl) (2004) 1.16
Acoustic startle, prepulse inhibition, and fear-potentiated startle measured in rhesus monkeys. Biol Psychiatry (2002) 1.15
Cross-linked microparticles as carriers for the delivery of plasmid DNA for vaccine development. Bioconjug Chem (2004) 1.15
Polyketal copolymers: a new acid-sensitive delivery vehicle for treating acute inflammatory diseases. Bioconjug Chem (2008) 1.14
Tools for translational neuroscience: PTSD is associated with heightened fear responses using acoustic startle but not skin conductance measures. Depress Anxiety (2011) 1.14
The role of neuropeptide Y in the expression and extinction of fear-potentiated startle. J Neurosci (2008) 1.14
Acute thrombosis of the inferior vena cava. Am J Emerg Med (2006) 1.13
Fear potentiation is associated with hypothalamic-pituitary-adrenal axis function in PTSD. Psychoneuroendocrinology (2009) 1.13
Strengthening the emergency healthcare system for mothers and children in The Gambia. Reprod Health (2010) 1.13
Polyketal microparticles: a new delivery vehicle for superoxide dismutase. Bioconjug Chem (2007) 1.12
Amygdala infusions of an NR2B-selective or an NR2A-preferring NMDA receptor antagonist differentially influence fear conditioning and expression in the fear-potentiated startle test. Learn Mem (2008) 1.10
The nonhuman primate amygdala is necessary for the acquisition but not the retention of fear-potentiated startle. Biol Psychiatry (2008) 1.10
Memory of social defeat is facilitated by cAMP response element-binding protein overexpression in the amygdala. Behav Neurosci (2005) 1.10
Estrogen disrupts the inhibition of fear in female rats, possibly through the antagonistic effects of estrogen receptor alpha (ERalpha) and ERbeta. J Neurosci (2007) 1.09
Calcitonin gene-related peptide in the bed nucleus of the stria terminalis produces an anxiety-like pattern of behavior and increases neural activation in anxiety-related structures. J Neurosci (2011) 1.08
Tumor pH-responsive flower-like micelles of poly(L-lactic acid)-b-poly(ethylene glycol)-b-poly(L-histidine). J Control Release (2007) 1.08
Acid-degradable particles for protein-based vaccines: enhanced survival rate for tumor-challenged mice using ovalbumin model. Bioconjug Chem (2004) 1.08
Role of the primate amygdala in fear-potentiated startle: effects of chronic lesions in the rhesus monkey. J Neurosci (2007) 1.07
Olfactory-mediated fear conditioning in mice: simultaneous measurements of fear-potentiated startle and freezing. Behav Neurosci (2005) 1.06
Physical activity loyalty cards for behavior change: a quasi-experimental study. Am J Prev Med (2013) 1.06
pH-sensitive polymers that enhance intracellular drug delivery in vivo. J Control Release (2002) 1.05
A virus-mimetic nanogel vehicle. Angew Chem Int Ed Engl (2008) 1.05
Modulation of fear-potentiated startle and vocalizations in juvenile rhesus monkeys by morphine, diazepam, and buspirone. Biol Psychiatry (2006) 1.05
Bioadhesive hydrogel microenvironments to modulate epithelial morphogenesis. Biomaterials (2008) 1.04