Published in J Mol Biol on June 18, 2010
Molecular structure of β-amyloid fibrils in Alzheimer's disease brain tissue. Cell (2013) 4.02
Distinct α-synuclein strains differentially promote tau inclusions in neurons. Cell (2013) 3.24
Purified and synthetic Alzheimer's amyloid beta (Aβ) prions. Proc Natl Acad Sci U S A (2012) 2.36
Molecular basis for amyloid-beta polymorphism. Proc Natl Acad Sci U S A (2011) 1.76
Antiparallel β-sheet architecture in Iowa-mutant β-amyloid fibrils. Proc Natl Acad Sci U S A (2012) 1.60
Conformation dependent monoclonal antibodies distinguish different replicating strains or conformers of prefibrillar Aβ oligomers. Mol Neurodegener (2010) 1.34
Serial propagation of distinct strains of Aβ prions from Alzheimer's disease patients. Proc Natl Acad Sci U S A (2014) 1.34
Molecular structures of amyloid and prion fibrils: consensus versus controversy. Acc Chem Res (2013) 1.29
Recent progress in understanding Alzheimer's β-amyloid structures. Trends Biochem Sci (2011) 1.24
Structural evolution of Iowa mutant β-amyloid fibrils from polymorphic to homogeneous states under repeated seeded growth. J Am Chem Soc (2011) 1.10
Polymorph-specific kinetics and thermodynamics of β-amyloid fibril growth. J Am Chem Soc (2013) 1.09
Prions and the potential transmissibility of protein misfolding diseases. Annu Rev Microbiol (2013) 1.04
Three- and four-repeat Tau coassemble into heterogeneous filaments: an implication for Alzheimer disease. J Biol Chem (2010) 1.03
Direct observation of heterogeneous amyloid fibril growth kinetics via two-color super-resolution microscopy. Nano Lett (2013) 1.02
Transient dynamics of Aβ contribute to toxicity in Alzheimer's disease. Cell Mol Life Sci (2014) 1.01
Dynamics of amyloid β fibrils revealed by solid-state NMR. J Biol Chem (2011) 1.01
Physical and structural basis for polymorphism in amyloid fibrils. Protein Sci (2014) 0.99
Structural variation in amyloid-β fibrils from Alzheimer's disease clinical subtypes. Nature (2017) 0.99
Assays for studying nucleated aggregation of polyglutamine proteins. Methods (2011) 0.97
Fiber diffraction data indicate a hollow core for the Alzheimer's aβ 3-fold symmetric fibril. J Mol Biol (2012) 0.96
Intrinsic linear heterogeneity of amyloid β protein fibrils revealed by higher resolution mass-per-length determinations. J Biol Chem (2010) 0.96
Biophysical insights into how surfaces, including lipid membranes, modulate protein aggregation related to neurodegeneration. Front Neurol (2013) 0.96
Amyloid polymorphism: structural basis and neurobiological relevance. Neuron (2015) 0.95
Kinetically competing huntingtin aggregation pathways control amyloid polymorphism and properties. Biochemistry (2012) 0.94
Vaccination with a non-human random sequence amyloid oligomer mimic results in improved cognitive function and reduced plaque deposition and micro hemorrhage in Tg2576 mice. Mol Neurodegener (2012) 0.92
Alzheimer's Aβ42 and Aβ40 peptides form interlaced amyloid fibrils. J Neurochem (2013) 0.90
Brain-Delivery of Zinc-Ions as Potential Treatment for Neurological Diseases: Mini Review. Drug Deliv Lett (2011) 0.89
Amyloid beta protein-induced zinc sequestration leads to synaptic loss via dysregulation of the ProSAP2/Shank3 scaffold. Mol Neurodegener (2011) 0.89
Aggregation behavior of chemically synthesized, full-length huntingtin exon1. Biochemistry (2014) 0.87
Probing fibril dissolution of the repeat domain of a functional amyloid, Pmel17, on the microscopic and residue level. Biochemistry (2011) 0.86
Antiparallel triple-strand architecture for prefibrillar Aβ42 oligomers. J Biol Chem (2014) 0.85
Point mutations in Aβ result in the formation of distinct polymorphic aggregates in the presence of lipid bilayers. PLoS One (2011) 0.84
Orientation of aromatic residues in amyloid cores: structural insights into prion fiber diversity. Proc Natl Acad Sci U S A (2014) 0.83
Countering amyloid polymorphism and drug resistance with minimal drug cocktails. Prion (2010) 0.83
Zn2+-Aβ40 complexes form metastable quasi-spherical oligomers that are cytotoxic to cultured hippocampal neurons. J Biol Chem (2012) 0.83
Polymorphism of Amyloid Fibrils In Vivo. Angew Chem Int Ed Engl (2016) 0.82
The glaucoma-associated olfactomedin domain of myocilin forms polymorphic fibrils that are constrained by partial unfolding and peptide sequence. J Mol Biol (2013) 0.82
Mapping the conformational dynamics and pathways of spontaneous steric zipper Peptide oligomerization. PLoS One (2011) 0.82
C-Terminal Threonine Reduces Aβ43 Amyloidogenicity Compared with Aβ42. J Mol Biol (2015) 0.81
Insights into the disparate action of osmolytes and macromolecular crowders on amyloid formation. Prion (2012) 0.81
Flexibility and Solvation of Amyloid-β Hydrophobic Core. J Biol Chem (2016) 0.81
Context dependence of protein misfolding and structural strains in neurodegenerative diseases. Biopolymers (2013) 0.80
A distinct subfraction of Aβ is responsible for the high-affinity Pittsburgh compound B-binding site in Alzheimer's disease brain. J Neurochem (2014) 0.79
Nucleation of polymorphic amyloid fibrils. Biophys J (2015) 0.78
Influence of temperature on formation of perfect tau fragment fibrils using PRIME20/DMD simulations. Protein Sci (2012) 0.78
Inflammation protein SAA2.2 spontaneously forms marginally stable amyloid fibrils at physiological temperature. Biochemistry (2011) 0.78
Progress towards structural understanding of infectious sheep PrP-amyloid. Prion (2014) 0.78
Strain-specific Fibril Propagation by an Aβ Dodecamer. Sci Rep (2017) 0.77
Fast Motions of Key Methyl Groups in Amyloid-β Fibrils. Biophys J (2016) 0.77
What amyloid ligands can tell us about molecular polymorphism and disease. Neurobiol Aging (2016) 0.77
Improved chemical synthesis of hydrophobic Aβ peptides using addition of C-terminal lysines later removed by carboxypeptidase B. Biopolymers (2014) 0.77
A structure-toxicity study of Aß42 reveals a new anti-parallel aggregation pathway. PLoS One (2013) 0.77
Conformational switch of polyglutamine-expanded huntingtin into benign aggregates leads to neuroprotective effect. Sci Rep (2015) 0.76
Acetylation within the First 17 Residues of Huntingtin Exon 1 Alters Aggregation and Lipid Binding. Biophys J (2016) 0.76
Point mutations in Aβ induce polymorphic aggregates at liquid/solid interfaces. ACS Chem Neurosci (2011) 0.76
β-Amyloid Prions and the Pathobiology of Alzheimer's Disease. Cold Spring Harb Perspect Med (2017) 0.75
Rapid α-oligomer formation mediated by the Aβ C terminus initiates an amyloid assembly pathway. Nat Commun (2016) 0.75
Alzheimer's disease--a panorama glimpse. Int J Mol Sci (2014) 0.75
Phosphorylation Interferes with Maturation of Amyloid-β Fibrillar Structure in the N Terminus. J Biol Chem (2016) 0.75
Impact of sequence on the molecular assembly of short amyloid peptides. Proteins (2014) 0.75
HIV Tat protein and amyloid-β peptide form multifibrillar structures that cause neurotoxicity. Nat Struct Mol Biol (2017) 0.75
Molecular Structure of Aggregated Amyloid-β: Insights from Solid-State Nuclear Magnetic Resonance. Cold Spring Harb Perspect Med (2016) 0.75
Cataract-associated P23T γD-crystallin retains a native-like fold in amorphous-looking aggregates formed at physiological pH. Nat Commun (2017) 0.75
Divalent copper ion bound amyloid-β(40) and amyloid-β(42) alloforms are less preferred than divalent zinc ion bound amyloid-β(40) and amyloid-β(42) alloforms. J Biol Inorg Chem (2016) 0.75
Looking at the recent advances in understanding α-synuclein and its aggregation through the proteoform prism. F1000Res (2017) 0.75
Binding of protofibrillar Aβ trimers to lipid bilayer surface enhances Aβ structural stability and causes membrane thinning. Phys Chem Chem Phys (2017) 0.75
Atomic structures of amyloid cross-beta spines reveal varied steric zippers. Nature (2007) 10.02
A structural model for Alzheimer's beta -amyloid fibrils based on experimental constraints from solid state NMR. Proc Natl Acad Sci U S A (2002) 9.55
Self-propagating, molecular-level polymorphism in Alzheimer's beta-amyloid fibrils. Science (2005) 8.86
3D structure of Alzheimer's amyloid-beta(1-42) fibrils. Proc Natl Acad Sci U S A (2005) 8.60
Protofibrils, pores, fibrils, and neurodegeneration: separating the responsible protein aggregates from the innocent bystanders. Annu Rev Neurosci (2003) 8.44
Molecular mechanisms of amyloidosis. N Engl J Med (2003) 7.75
Experimental constraints on quaternary structure in Alzheimer's beta-amyloid fibrils. Biochemistry (2006) 6.54
Conformational variations in an infectious protein determine prion strain differences. Nature (2004) 6.15
Self-replication and scrapie. Nature (1967) 6.01
Quantification of beta-sheet amyloid fibril structures with thioflavin T. Methods Enzymol (1999) 5.89
Amyloid fibrils of the HET-s(218-289) prion form a beta solenoid with a triangular hydrophobic core. Science (2008) 5.55
Molecular structural basis for polymorphism in Alzheimer's beta-amyloid fibrils. Proc Natl Acad Sci U S A (2008) 4.84
Protein-only transmission of three yeast prion strains. Nature (2004) 4.76
On the nucleation and growth of amyloid beta-protein fibrils: detection of nuclei and quantitation of rate constants. Proc Natl Acad Sci U S A (1996) 4.75
The use and misuse of FTIR spectroscopy in the determination of protein structure. Crit Rev Biochem Mol Biol (1995) 3.74
Structural and dynamic features of Alzheimer's Abeta peptide in amyloid fibrils studied by site-directed spin labeling. J Biol Chem (2002) 3.37
The structural basis of yeast prion strain variants. Nature (2007) 3.31
Mapping abeta amyloid fibril secondary structure using scanning proline mutagenesis. J Mol Biol (2004) 3.05
Polymorphism in the intermediates and products of amyloid assembly. Curr Opin Struct Biol (2007) 2.75
Structural features of the Abeta amyloid fibril elucidated by limited proteolysis. Biochemistry (2001) 2.64
Design and construction of diverse mammalian prion strains. Proc Natl Acad Sci U S A (2009) 2.41
Seeding specificity in amyloid growth induced by heterologous fibrils. J Biol Chem (2004) 2.35
A recessive mutation in the APP gene with dominant-negative effect on amyloidogenesis. Science (2009) 2.30
Molecular mechanism of Thioflavin-T binding to amyloid fibrils. Biochim Biophys Acta (2010) 2.22
Studies on the in vitro assembly of a beta 1-40: implications for the search for a beta fibril formation inhibitors. J Struct Biol (2000) 2.19
Seeded growth of beta-amyloid fibrils from Alzheimer's brain-derived fibrils produces a distinct fibril structure. Proc Natl Acad Sci U S A (2009) 2.15
Apolipoprotein E is a kinetic but not a thermodynamic inhibitor of amyloid formation: implications for the pathogenesis and treatment of Alzheimer disease. Proc Natl Acad Sci U S A (1995) 2.11
Fibril conformation as the basis of species- and strain-dependent seeding specificity of mammalian prion amyloids. Cell (2005) 2.06
Abeta amyloid fibrils possess a core structure highly resistant to hydrogen exchange. Proc Natl Acad Sci U S A (2000) 2.02
Active and passive immunotherapy for neurodegenerative disorders. Annu Rev Neurosci (2008) 2.01
Molecular basis of the neurodegenerative disorders. N Engl J Med (1999) 2.00
Solid-state NMR study of amyloid nanocrystals and fibrils formed by the peptide GNNQQNY from yeast prion protein Sup35p. J Am Chem Soc (2007) 1.96
Protein aggregation in the brain: the molecular basis for Alzheimer's and Parkinson's diseases. Mol Med (2008) 1.90
Paired beta-sheet structure of an Abeta(1-40) amyloid fibril revealed by electron microscopy. Proc Natl Acad Sci U S A (2008) 1.89
Beta-amyloid, blood vessels, and brain function. Stroke (2009) 1.89
Abeta(1-40) fibril polymorphism implies diverse interaction patterns in amyloid fibrils. J Mol Biol (2008) 1.86
Thermodynamics of A beta(1-40) amyloid fibril elongation. Biochemistry (2005) 1.81
The chemistry of scrapie infection: implications of the 'ice 9' metaphor. Chem Biol (1995) 1.76
Kinetics and thermodynamics of amyloid fibril assembly. Acc Chem Res (2006) 1.71
The common architecture of cross-beta amyloid. J Mol Biol (2009) 1.69
Kinetics and thermodynamics of amyloid assembly using a high-performance liquid chromatography-based sedimentation assay. Methods Enzymol (2006) 1.66
Nucleation-dependent polymerization is an essential component of amyloid-mediated neuronal cell death. J Neurosci (2005) 1.56
Alanine scanning mutagenesis of Abeta(1-40) amyloid fibril stability. J Mol Biol (2006) 1.55
The solvent protection of alzheimer amyloid-beta-(1-42) fibrils as determined by solution NMR spectroscopy. J Biol Chem (2005) 1.53
Manipulating the amyloid-beta aggregation pathway with chemical chaperones. J Biol Chem (1999) 1.50
Hydrogen-deuterium (H/D) exchange mapping of Abeta 1-40 amyloid fibril secondary structure using nuclear magnetic resonance spectroscopy. Biochemistry (2005) 1.46
X-ray fiber diffraction of amyloid fibrils. Methods Enzymol (1999) 1.45
Physical, morphological and functional differences between ph 5.8 and 7.4 aggregates of the Alzheimer's amyloid peptide Abeta. J Mol Biol (1996) 1.45
Generic hydrophobic residues are sufficient to promote aggregation of the Alzheimer's Abeta42 peptide. Proc Natl Acad Sci U S A (2006) 1.44
Plasticity of amyloid fibrils. Biochemistry (2007) 1.43
Structural properties of Abeta protofibrils stabilized by a small molecule. Proc Natl Acad Sci U S A (2005) 1.40
Sequence of Abeta-protein deposition in the human medial temporal lobe. J Neuropathol Exp Neurol (2000) 1.37
Interactions of Alzheimer amyloid-beta peptides with glycosaminoglycans effects on fibril nucleation and growth. Eur J Biochem (1999) 1.27
Structural differences in Abeta amyloid protofibrils and fibrils mapped by hydrogen exchange--mass spectrometry with on-line proteolytic fragmentation. J Mol Biol (2006) 1.26
Molecular basis for passive immunotherapy of Alzheimer's disease. Proc Natl Acad Sci U S A (2007) 1.26
Amide solvent protection analysis demonstrates that amyloid-beta(1-40) and amyloid-beta(1-42) form different fibrillar structures under identical conditions. Biochem J (2007) 1.24
Abeta protofibrils possess a stable core structure resistant to hydrogen exchange. Biochemistry (2003) 1.23
An intersheet packing interaction in A beta fibrils mapped by disulfide cross-linking. Biochemistry (2004) 1.17
Seeding-dependent propagation and maturation of amyloid fibril conformation. J Mol Biol (2005) 1.15
Sidechain interactions in parallel beta sheets: the energetics of cross-strand pairings. Structure (1999) 1.13
Scanning cysteine mutagenesis analysis of Abeta-(1-40) amyloid fibrils. J Biol Chem (2005) 1.12
Zinc-amyloid beta interactions on a millisecond time-scale stabilize non-fibrillar Alzheimer-related species. J Am Chem Soc (2008) 1.11
Hydrogen/deuterium exchange mass spectrometry--a window into amyloid structure. Acc Chem Res (2006) 1.07
Amyloid-beta protofibrils differ from amyloid-beta aggregates induced in dilute hexafluoroisopropanol in stability and morphology. J Biol Chem (2004) 1.03
Visualization and classification of amyloid beta supramolecular assemblies. Biochemistry (2007) 1.02
Analysis of the tertiary structure of protein beta-sheet sandwiches. J Mol Biol (1981) 1.02
Hydrogen/deuterium exchange mass spectrometry analysis of protein aggregates. Methods Enzymol (2006) 0.93
Is passive immunization for Alzheimer's disease 'alive and well' or 'dead and buried'? Expert Opin Biol Ther (2009) 0.92
Enhanced correction methods for hydrogen exchange-mass spectrometric studies of amyloid fibrils. Protein Sci (2003) 0.89
Inconvenient facts about pathological amyloid fibrils. Proc Natl Acad Sci U S A (2009) 0.80
Huntington's disease age-of-onset linked to polyglutamine aggregation nucleation. Proc Natl Acad Sci U S A (2002) 3.56
Mapping abeta amyloid fibril secondary structure using scanning proline mutagenesis. J Mol Biol (2004) 3.05
Eukaryotic proteasomes cannot digest polyglutamine sequences and release them during degradation of polyglutamine-containing proteins. Mol Cell (2004) 2.89
Polyglutamine disruption of the huntingtin exon 1 N terminus triggers a complex aggregation mechanism. Nat Struct Mol Biol (2009) 2.77
Polymorphism in the intermediates and products of amyloid assembly. Curr Opin Struct Biol (2007) 2.75
Conformational Abs recognizing a generic amyloid fibril epitope. Proc Natl Acad Sci U S A (2002) 2.62
Amyloid-like features of polyglutamine aggregates and their assembly kinetics. Biochemistry (2002) 2.59
Aggregated polyglutamine peptides delivered to nuclei are toxic to mammalian cells. Hum Mol Genet (2002) 2.44
Serines 13 and 16 are critical determinants of full-length human mutant huntingtin induced disease pathogenesis in HD mice. Neuron (2009) 2.43
Seeding specificity in amyloid growth induced by heterologous fibrils. J Biol Chem (2004) 2.35
Amyloid adhesins are abundant in natural biofilms. Environ Microbiol (2007) 2.35
Oligoproline effects on polyglutamine conformation and aggregation. J Mol Biol (2005) 2.14
Fluorescence correlation spectroscopy shows that monomeric polyglutamine molecules form collapsed structures in aqueous solutions. Proc Natl Acad Sci U S A (2006) 2.00
Mutational analysis of the structural organization of polyglutamine aggregates. Proc Natl Acad Sci U S A (2002) 1.89
Absence of behavioral abnormalities and neurodegeneration in vivo despite widespread neuronal huntingtin inclusions. Proc Natl Acad Sci U S A (2005) 1.87
Thermodynamics of A beta(1-40) amyloid fibril elongation. Biochemistry (2005) 1.81
Kinetic analysis of beta-amyloid fibril elongation. Anal Biochem (2004) 1.78
Kinetics and thermodynamics of amyloid assembly using a high-performance liquid chromatography-based sedimentation assay. Methods Enzymol (2006) 1.66
Critical nucleus size for disease-related polyglutamine aggregation is repeat-length dependent. Nat Struct Mol Biol (2011) 1.60
polyglutamine aggregation nucleation: thermodynamics of a highly unfavorable protein folding reaction. Proc Natl Acad Sci U S A (2005) 1.57
Alanine scanning mutagenesis of Abeta(1-40) amyloid fibril stability. J Mol Biol (2006) 1.55
Hydrogen-deuterium (H/D) exchange mapping of Abeta 1-40 amyloid fibril secondary structure using nuclear magnetic resonance spectroscopy. Biochemistry (2005) 1.46
Plasticity of amyloid fibrils. Biochemistry (2007) 1.43
Structural properties of Abeta protofibrils stabilized by a small molecule. Proc Natl Acad Sci U S A (2005) 1.40
The aggregation-enhancing huntingtin N-terminus is helical in amyloid fibrils. J Am Chem Soc (2011) 1.37
Structural differences in Abeta amyloid protofibrils and fibrils mapped by hydrogen exchange--mass spectrometry with on-line proteolytic fragmentation. J Mol Biol (2006) 1.26
Molecular basis for passive immunotherapy of Alzheimer's disease. Proc Natl Acad Sci U S A (2007) 1.26
Behavioral abnormalities precede neuropathological markers in rats transgenic for Huntington's disease. Hum Mol Genet (2006) 1.25
Abeta protofibrils possess a stable core structure resistant to hydrogen exchange. Biochemistry (2003) 1.23
Polyglutamine homopolymers having 8-45 residues form slablike beta-crystallite assemblies. Proteins (2005) 1.22
Normal-repeat-length polyglutamine peptides accelerate aggregation nucleation and cytotoxicity of expanded polyglutamine proteins. Proc Natl Acad Sci U S A (2006) 1.21
In-cell aggregation of a polyglutamine-containing chimera is a multistep process initiated by the flanking sequence. J Biol Chem (2007) 1.19
Soluble and mature amyloid fibrils in drusen deposits. Invest Ophthalmol Vis Sci (2009) 1.18
Slow amyloid nucleation via α-helix-rich oligomeric intermediates in short polyglutamine-containing huntingtin fragments. J Mol Biol (2011) 1.17
An intersheet packing interaction in A beta fibrils mapped by disulfide cross-linking. Biochemistry (2004) 1.17
Molecular modeling of the core of Abeta amyloid fibrils. Proteins (2004) 1.16
Apolipoprotein A-I deficiency increases cerebral amyloid angiopathy and cognitive deficits in APP/PS1DeltaE9 mice. J Biol Chem (2010) 1.16
Imaging polyglutamine deposits in brain tissue. Methods Enzymol (2006) 1.13
Scanning cysteine mutagenesis analysis of Abeta-(1-40) amyloid fibrils. J Biol Chem (2005) 1.12
Hydrogen/deuterium exchange mass spectrometry--a window into amyloid structure. Acc Chem Res (2006) 1.07
Inhibiting the nucleation of amyloid structure in a huntingtin fragment by targeting α-helix-rich oligomeric intermediates. J Mol Biol (2011) 1.03
The impact of ataxin-1-like histidine insertions on polyglutamine aggregation. Protein Eng Des Sel (2009) 0.97
Assays for studying nucleated aggregation of polyglutamine proteins. Methods (2011) 0.97
Human plasma contains cross-reactive Abeta conformer-specific IgG antibodies. Biochemistry (2008) 0.96
β-hairpin-mediated nucleation of polyglutamine amyloid formation. J Mol Biol (2013) 0.96
Serine phosphorylation suppresses huntingtin amyloid accumulation by altering protein aggregation properties. J Mol Biol (2012) 0.95
CA150 expression delays striatal cell death in overexpression and knock-in conditions for mutant huntingtin neurotoxicity. J Neurosci (2006) 0.95
Kinetically competing huntingtin aggregation pathways control amyloid polymorphism and properties. Biochemistry (2012) 0.94
Polyglutamine amyloid core boundaries and flanking domain dynamics in huntingtin fragment fibrils determined by solid-state nuclear magnetic resonance. Biochemistry (2014) 0.93
Hydrogen/deuterium exchange mass spectrometry analysis of protein aggregates. Methods Enzymol (2006) 0.93
Inhibition of polyglutamine aggregate cytotoxicity by a structure-based elongation inhibitor. FASEB J (2004) 0.90
Enhanced correction methods for hydrogen exchange-mass spectrometric studies of amyloid fibrils. Protein Sci (2003) 0.89
Anti-amyloidogenic activity of IgGs contained in normal plasma. J Clin Immunol (2010) 0.88
Structural variations in the cross-beta core of amyloid beta fibrils revealed by deep UV resonance Raman spectroscopy. J Am Chem Soc (2010) 0.88
Distinct thymidine kinases encoded by cowpox virus and herpes simplex virus contribute significantly to the differential antiviral activity of nucleoside analogs. Antiviral Res (2006) 0.87
Aggregation behavior of chemically synthesized, full-length huntingtin exon1. Biochemistry (2014) 0.87
Biophysical underpinnings of the repeat length dependence of polyglutamine amyloid formation. J Biol Chem (2014) 0.87
Nucleation of huntingtin aggregation in cells. Nat Chem Biol (2006) 0.85
Analysis of amyloid fibril structure by scanning cysteine mutagenesis. Methods Enzymol (2006) 0.83
Therapeutic versus neuroinflammatory effects of passive immunization is dependent on Aβ/amyloid burden in a transgenic mouse model of Alzheimer's disease. J Neuroinflammation (2010) 0.82
Structures of Abeta-related peptide--monoclonal antibody complexes. Biochemistry (2009) 0.82
Screening for modulators of aggregation with a microplate elongation assay. Methods Enzymol (2006) 0.81
Levels of supramolecular chirality of polyglutamine aggregates revealed by vibrational circular dichroism. FEBS Lett (2013) 0.81
A serendipitous survey of prediction algorithms for amyloidogenicity. Biopolymers (2013) 0.79
Amyloid fibrils--common threads in the natural history of proteins. Acc Chem Res (2006) 0.78
Human anti-Aβ IgGs target conformational epitopes on synthetic dimer assemblies and the AD brain-derived peptide. PLoS One (2012) 0.77
An assay for characterizing in vitro the kinetics of polyglutamine aggregation. Methods Mol Biol (2003) 0.77
Improved chemical synthesis of hydrophobic Aβ peptides using addition of C-terminal lysines later removed by carboxypeptidase B. Biopolymers (2014) 0.77
A triaxial probe for on-line proteolysis coupled with hydrogen/deuterium exchange-electrospray mass spectrometry. J Am Soc Mass Spectrom (2006) 0.76
Common threads in neurodegenerative disorders of aging. Alzheimers Dement (2006) 0.76