Published in Arch Gen Psychiatry on July 01, 2010
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De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia. Mol Psychiatry (2011) 4.91
Neurodevelopmental hypothesis of schizophrenia. Br J Psychiatry (2011) 1.87
Shared polygenic contribution between childhood attention-deficit hyperactivity disorder and adult schizophrenia. Br J Psychiatry (2013) 1.70
Evidence that duplications of 22q11.2 protect against schizophrenia. Mol Psychiatry (2013) 1.20
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Association of the type 2 diabetes mellitus susceptibility gene, TCF7L2, with schizophrenia in an Arab-Israeli family sample. PLoS One (2012) 0.99
In utero electroporation as a tool for genetic manipulation in vivo to study psychiatric disorders: from genes to circuits and behaviors. Neuroscientist (2011) 0.94
Implications of genetic findings for understanding schizophrenia. Schizophr Bull (2012) 0.94
Reduced levels of serotonin 2A receptors underlie resistance of Egr3-deficient mice to locomotor suppression by clozapine. Neuropsychopharmacology (2012) 0.90
Clinical and cognitive characteristics of children with attention-deficit hyperactivity disorder, with and without copy number variants. Br J Psychiatry (2011) 0.90
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The clinical-basic interface in defining pathogenesis in disorders of neurodevelopmental origin. Neuron (2010) 0.85
Meta-analysis indicates that the European GWAS-identified risk SNP rs1344706 within ZNF804A is not associated with schizophrenia in Han Chinese population. PLoS One (2013) 0.85
Comparison of the heritability of schizophrenia and endophenotypes in the COGS-1 family study. Schizophr Bull (2014) 0.85
Evidence for varied aetiologies regulating the transmission of prion disease: implications for understanding the heritable basis of prion incubation times. PLoS One (2010) 0.84
From antipsychotic to anti-schizophrenia drugs: role of animal models. Trends Pharmacol Sci (2012) 0.84
Avoiding mouse traps in schizophrenia genetics: lessons and promises from current and emerging mouse models. Neuroscience (2011) 0.84
Lack of use in the literature from the last 20 years supports dropping traditional schizophrenia subtypes from DSM-5 and ICD-11. Schizophr Bull (2013) 0.83
Modeling resilience to schizophrenia in genetically modified mice: a novel approach to drug discovery. Expert Rev Neurother (2012) 0.81
MicroRNA-137 Inhibits EFNB2 Expression Affected by a Genetic Variant and Is Expressed Aberrantly in Peripheral Blood of Schizophrenia Patients. EBioMedicine (2016) 0.81
Meta-analysis of sex differences in gene expression in schizophrenia. BMC Syst Biol (2016) 0.77
Excess of homozygosity in the major histocompatibility complex in schizophrenia. Hum Mol Genet (2014) 0.77
Recent Positive Selection Drives the Expansion of a Schizophrenia Risk Nonsynonymous Variant at SLC39A8 in Europeans. Schizophr Bull (2015) 0.76
Overview of the Genetics of Alcohol Use Disorder. Alcohol Alcohol (2016) 0.76
Sex differences in GABAergic gene expression occur in the anterior cingulate cortex in schizophrenia. Schizophr Res (2015) 0.76
Proteomic enrichment analysis of psychotic and affective disorders reveals common signatures in presynaptic glutamatergic signaling and energy metabolism. Int J Neuropsychopharmacol (2014) 0.76
The Association between COMT, BDNF, and NRG1 and Premorbid Social Functioning in Patients with Psychosis, Their Relatives, and Controls. Scientifica (Cairo) (2012) 0.76
Association of the ZFPM2 gene with antipsychotic-induced parkinsonism in schizophrenia patients. Psychopharmacology (Berl) (2011) 0.75
Resequencing and association analysis of PTPRA, a possible susceptibility gene for schizophrenia and autism spectrum disorders. PLoS One (2014) 0.75
Proteomics Research in Schizophrenia. Front Cell Neurosci (2016) 0.75
Novel genetic advances in schizophrenia: an interview with Michael O'Donovan. BMC Med (2015) 0.75
The clinical presentation of attention deficit-hyperactivity disorder (ADHD) in children with 22q11.2 deletion syndrome. Am J Med Genet B Neuropsychiatr Genet (2015) 0.75
Comorbid substance use disorders in schizophrenia: a latent class approach. Psychiatry Res (2014) 0.75
Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature (2009) 33.26
Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants. Nat Genet (2007) 12.62
Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls. Nature (2010) 12.27
Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. Nat Genet (2008) 10.49
Wake-up call for British psychiatry. Br J Psychiatry (2008) 10.30
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet (2013) 8.02
Genome-wide association analysis identifies 13 new risk loci for schizophrenia. Nat Genet (2013) 7.44
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A mega-analysis of genome-wide association studies for major depressive disorder. Mol Psychiatry (2012) 6.34
Microduplications of 16p11.2 are associated with schizophrenia. Nat Genet (2009) 6.13
Gene ontology analysis of GWA study data sets provides insights into the biology of bipolar disorder. Am J Hum Genet (2009) 5.98
Comparative genome hybridization suggests a role for NRXN1 and APBA2 in schizophrenia. Hum Mol Genet (2007) 5.28
Genomewide association studies: history, rationale, and prospects for psychiatric disorders. Am J Psychiatry (2009) 4.74
Support for the involvement of large copy number variants in the pathogenesis of schizophrenia. Hum Mol Genet (2009) 4.52
The beginning of the end for the Kraepelinian dichotomy. Br J Psychiatry (2005) 4.51
Genes for schizophrenia and bipolar disorder? Implications for psychiatric nosology. Schizophr Bull (2005) 3.93
Discovery and statistical genotyping of copy-number variation from whole-exome sequencing depth. Am J Hum Genet (2012) 3.50
Bayesian refinement of association signals for 14 loci in 3 common diseases. Nat Genet (2012) 3.31
Combined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q. Am J Hum Genet (2005) 3.24
Cis-acting variation in the expression of a high proportion of genes in human brain. Hum Genet (2003) 3.07
Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: Bipolar disorder. Am J Hum Genet (2003) 3.02
Analysis of copy number variations at 15 schizophrenia-associated loci. Br J Psychiatry (2013) 3.01
Phenotypic and genetic complexity of psychosis. Invited commentary on ... Schizophrenia: a common disease caused by multiple rare alleles. Br J Psychiatry (2007) 2.97
A comprehensive family-based replication study of schizophrenia genes. JAMA Psychiatry (2013) 2.93
Genome-wide association study identifies genetic variation in neurocan as a susceptibility factor for bipolar disorder. Am J Hum Genet (2011) 2.71
Improved detection of common variants associated with schizophrenia and bipolar disorder using pleiotropy-informed conditional false discovery rate. PLoS Genet (2013) 2.68
Dissecting the phenotype in genome-wide association studies of psychiatric illness. Br J Psychiatry (2009) 2.65
Operation of the schizophrenia susceptibility gene, neuregulin 1, across traditional diagnostic boundaries to increase risk for bipolar disorder. Arch Gen Psychiatry (2005) 2.58
Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease. PLoS One (2010) 2.57
Genome-wide analysis of copy number variants in attention deficit hyperactivity disorder: the role of rare variants and duplications at 15q13.3. Am J Psychiatry (2012) 2.48
The genetic deconstruction of psychosis. Schizophr Bull (2007) 2.25
Neurexin 1 (NRXN1) deletions in schizophrenia. Schizophr Bull (2009) 2.25
Effects of differential genotyping error rate on the type I error probability of case-control studies. Hum Hered (2006) 2.21
Common variants at VRK2 and TCF4 conferring risk of schizophrenia. Hum Mol Genet (2011) 2.21
A genome-wide association study for late-onset Alzheimer's disease using DNA pooling. BMC Med Genomics (2008) 2.20
Risk of psychopathology in adolescent offspring of mothers with psychopathology and recurrent depression. Br J Psychiatry (2012) 2.19
Polymorphism of the 5-HT transporter and response to antidepressants: randomised controlled trial. Br J Psychiatry (2011) 2.18
Genetic variation of brain-derived neurotrophic factor (BDNF) in bipolar disorder: case-control study of over 3000 individuals from the UK. Br J Psychiatry (2006) 2.16
A haplotype implicated in schizophrenia susceptibility is associated with reduced COMT expression in human brain. Am J Hum Genet (2003) 2.11
Rare copy number variants: a point of rarity in genetic risk for bipolar disorder and schizophrenia. Arch Gen Psychiatry (2010) 2.11
All SNPs are not created equal: genome-wide association studies reveal a consistent pattern of enrichment among functionally annotated SNPs. PLoS Genet (2013) 2.08
Characterization of a family with rare deletions in CNTNAP5 and DOCK4 suggests novel risk loci for autism and dyslexia. Biol Psychiatry (2010) 2.07
Tbx1 haploinsufficiency is linked to behavioral disorders in mice and humans: implications for 22q11 deletion syndrome. Proc Natl Acad Sci U S A (2006) 2.03
Universal, robust, highly quantitative SNP allele frequency measurement in DNA pools. Hum Genet (2002) 2.03
The bicentennial volume of the British Journal of Psychiatry: the winding pathway of mental science. Br J Psychiatry (2012) 2.01
Adolescent clinical outcomes for young people with attention-deficit hyperactivity disorder. Br J Psychiatry (2010) 1.99
Pooled DNA genotyping on Affymetrix SNP genotyping arrays. BMC Genomics (2006) 1.96
Improved detection of common variants associated with schizophrenia by leveraging pleiotropy with cardiovascular-disease risk factors. Am J Hum Genet (2013) 1.96
Maternally derived microduplications at 15q11-q13: implication of imprinted genes in psychotic illness. Am J Psychiatry (2011) 1.94
Strong evidence that KIAA0319 on chromosome 6p is a susceptibility gene for developmental dyslexia. Am J Hum Genet (2005) 1.93
Genome-wide association study of schizophrenia in a Japanese population. Biol Psychiatry (2010) 1.89
De novo rates and selection of schizophrenia-associated copy number variants. Biol Psychiatry (2011) 1.87
Neurodevelopmental hypothesis of schizophrenia. Br J Psychiatry (2011) 1.87
Genome-wide association study of suicide attempts in mood disorder patients. Am J Psychiatry (2010) 1.85
Medical disorders in people with recurrent depression. Br J Psychiatry (2008) 1.75
Unrecognised bipolar disorder in primary care patients with depression. Br J Psychiatry (2011) 1.74
Haplotypes at the dystrobrevin binding protein 1 (DTNBP1) gene locus mediate risk for schizophrenia through reduced DTNBP1 expression. Hum Mol Genet (2005) 1.72
Most genome-wide significant susceptibility loci for schizophrenia and bipolar disorder reported to date cross-traditional diagnostic boundaries. Hum Mol Genet (2010) 1.72
DNA pooling as a tool for large-scale association studies in complex traits. Ann Med (2004) 1.70
Shared polygenic contribution between childhood attention-deficit hyperactivity disorder and adult schizophrenia. Br J Psychiatry (2013) 1.70
Functional analysis of human promoter polymorphisms. Hum Mol Genet (2003) 1.69
Evidence that interaction between neuregulin 1 and its receptor erbB4 increases susceptibility to schizophrenia. Am J Med Genet B Neuropsychiatr Genet (2006) 1.61
Clinical differences between bipolar and unipolar depression. Br J Psychiatry (2008) 1.58
Phenotypic variations on the theme of CNVs. Nat Genet (2008) 1.58
No major schizophrenia locus detected on chromosome 1q in a large multicenter sample. Science (2002) 1.57
Risk of puerperal and non-puerperal recurrence of illness following bipolar affective puerperal (post-partum) psychosis. Br J Psychiatry (2005) 1.56
Cognitive style in bipolar disorder. Br J Psychiatry (2005) 1.55
Incidence of hospitalization for postpartum psychotic and bipolar episodes. Arch Gen Psychiatry (2008) 1.54
Maternal depression and co-occurring antisocial behaviour: testing maternal hostility and warmth as mediators of risk for offspring psychopathology. J Child Psychol Psychiatry (2013) 1.52
MECP2 structural and 3'-UTR variants in schizophrenia, autism and other psychiatric diseases: a possible association with autism. Am J Med Genet B Neuropsychiatr Genet (2004) 1.51
SORL1 variants and risk of late-onset Alzheimer's disease. Neurobiol Dis (2007) 1.49
Copy number variation in schizophrenia in the Japanese population. Biol Psychiatry (2009) 1.49
Strong bias in the location of functional promoter polymorphisms. Hum Mutat (2005) 1.48
Genomewide linkage scan in schizoaffective disorder: significant evidence for linkage at 1q42 close to DISC1, and suggestive evidence at 22q11 and 19p13. Arch Gen Psychiatry (2005) 1.48
The role of the major histocompatibility complex region in cognition and brain structure: a schizophrenia GWAS follow-up. Am J Psychiatry (2013) 1.48
Psychosis susceptibility gene ZNF804A and cognitive performance in schizophrenia. Arch Gen Psychiatry (2010) 1.46
Bipolar affective puerperal psychosis: genome-wide significant evidence for linkage to chromosome 16. Am J Psychiatry (2007) 1.46
A genomewide linkage study on suicidality in major depressive disorder confirms evidence for linkage to 2p12. Am J Med Genet B Neuropsychiatr Genet (2010) 1.44
A network of dopaminergic gene variations implicated as risk factors for schizophrenia. Hum Mol Genet (2007) 1.43
Functional analysis of polymorphisms in the promoter regions of genes on 22q11. Hum Mutat (2004) 1.43
A genome-wide significant linkage for severe depression on chromosome 3: the depression network study. Am J Psychiatry (2011) 1.41
Correction: Improved Detection of Common Variants Associated with Schizophrenia and Bipolar Disorder Using Pleiotropy-Informed Conditional False Discovery Rate. PLoS Genet (2015) 1.39