Published in BMC Genomics on February 15, 2006
Genome-wide association identifies a common variant in the reelin gene that increases the risk of schizophrenia only in women. PLoS Genet (2008) 3.33
Highly cost-efficient genome-wide association studies using DNA pools and dense SNP arrays. Nucleic Acids Res (2008) 3.08
Molecular genetics of adult ADHD: converging evidence from genome-wide association and extended pedigree linkage studies. J Neural Transm (Vienna) (2008) 2.43
A whole genome association study of neuroticism using DNA pooling. Mol Psychiatry (2007) 2.30
A genome-wide association study for late-onset Alzheimer's disease using DNA pooling. BMC Med Genomics (2008) 2.20
Genome-wide quantitative trait locus association scan of general cognitive ability using pooled DNA and 500K single nucleotide polymorphism microarrays. Genes Brain Behav (2008) 2.08
A three-stage genome-wide association study of general cognitive ability: hunting the small effects. Behav Genet (2010) 1.85
A genome-wide association study of social and non-social autistic-like traits in the general population using pooled DNA, 500 K SNP microarrays and both community and diagnosed autism replication samples. Behav Genet (2009) 1.75
Bisulfite-based epityping on pooled genomic DNA provides an accurate estimate of average group DNA methylation. Epigenetics Chromatin (2009) 1.29
A genome-wide association study identifies multiple loci associated with mathematics ability and disability. Genes Brain Behav (2009) 1.25
Applicability of DNA pools on 500 K SNP microarrays for cost-effective initial screens in genomewide association studies. BMC Genomics (2007) 1.22
The SNPMaP package for R: a framework for genome-wide association using DNA pooling on microarrays. Bioinformatics (2008) 1.15
MPDA: microarray pooled DNA analyzer. BMC Bioinformatics (2008) 1.11
Genome wide allele frequency fingerprints (GWAFFs) of populations via genotyping by sequencing. PLoS One (2013) 1.11
FREQ-Seq: a rapid, cost-effective, sequencing-based method to determine allele frequencies directly from mixed populations. PLoS One (2012) 1.01
Genome-wide association study identifies genes that may contribute to risk for developing heroin addiction. Psychiatr Genet (2010) 0.99
Optimal DNA pooling-based two-stage designs in case-control association studies. Hum Hered (2008) 0.97
Fish scales and SNP chips: SNP genotyping and allele frequency estimation in individual and pooled DNA from historical samples of Atlantic salmon (Salmo salar). BMC Genomics (2013) 0.96
A DArT platform for quantitative bulked segregant analysis. BMC Genomics (2007) 0.93
Assignment of SNP allelic configuration in polyploids using competitive allele-specific PCR: application to citrus triploid progeny. Ann Bot (2013) 0.93
Allelotyping of pooled DNA with 250 K SNP microarrays. BMC Genomics (2007) 0.93
Whole genome association study in a homogenous population in Shandong peninsula of China reveals JARID2 as a susceptibility gene for schizophrenia. J Biomed Biotechnol (2009) 0.89
Association study in the 5q31-32 linkage region for schizophrenia using pooled DNA genotyping. BMC Psychiatry (2008) 0.88
The nature of nurture: a genomewide association scan for family chaos. Behav Genet (2008) 0.87
Validation of pooled genotyping on the Affymetrix 500 k and SNP6.0 genotyping platforms using the polynomial-based probe-specific correction. BMC Genet (2009) 0.87
Quality of DNA extracted from mouthwashes. PLoS One (2009) 0.86
Utility of the pooling approach as applied to whole genome association scans with high-density Affymetrix microarrays. BMC Res Notes (2010) 0.82
A novel candidate region for genetic adaptation to high altitude in Andean populations. PLoS One (2015) 0.81
A new analysis tool for individual-level allele frequency for genomic studies. BMC Genomics (2010) 0.80
Whole-miRNome profiling identifies prognostic serum miRNAs in esophageal adenocarcinoma: the influence of Helicobacter pylori infection status. Carcinogenesis (2014) 0.79
Microarray-based estimation of SNP allele-frequency in pooled DNA using the Langmuir kinetic model. BMC Genomics (2008) 0.78
Evaluation of quality of DNA extracted from buccal swabs for microarray based genotyping. Indian J Clin Biochem (2011) 0.78
Incorporation of genetic model parameters for cost-effective designs of genetic association studies using DNA pooling. BMC Genomics (2007) 0.78
A comparison of association statistics between pooled and individual genotypes. Hum Hered (2009) 0.77
Multicentric Genome-Wide Association Study for Primary Spontaneous Pneumothorax. PLoS One (2016) 0.75
Disentangling pooled triad genotypes for association studies. Ann Hum Genet (2014) 0.75
A genome-wide association study of essential hypertension in an Australian population using a DNA pooling approach. Mol Genet Genomics (2016) 0.75
Complement factor H polymorphism in age-related macular degeneration. Science (2005) 31.10
Prospects for whole-genome linkage disequilibrium mapping of common disease genes. Nat Genet (1999) 25.93
Whole-genome patterns of common DNA variation in three human populations. Science (2005) 21.22
Searching for genetic determinants in the new millennium. Nature (2000) 17.50
Association study designs for complex diseases. Nat Rev Genet (2001) 8.91
DNA Pooling: a tool for large-scale association studies. Nat Rev Genet (2002) 5.66
Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease. Hum Mol Genet (2005) 5.35
The relative power of family-based and case-control designs for linkage disequilibrium studies of complex human diseases I. DNA pooling. Genome Res (1998) 5.11
Algorithms for large-scale genotyping microarrays. Bioinformatics (2003) 2.66
Cheap, accurate and rapid allele frequency estimation of single nucleotide polymorphisms by primer extension and DHPLC in DNA pools. Hum Genet (2000) 2.26
Genotyping pooled DNA on microarrays: a systematic genome screen of thousands of SNPs in large samples to detect QTLs for complex traits. Behav Genet (2004) 2.14
SNP genotyping on pooled DNAs: comparison of genotyping technologies and a semi automated method for data storage and analysis. Nucleic Acids Res (2002) 2.12
Association mapping of disease loci, by use of a pooled DNA genomic screen. Am J Hum Genet (1997) 2.07
Universal, robust, highly quantitative SNP allele frequency measurement in DNA pools. Hum Genet (2002) 2.03
Pooled association genome scanning: validation and use to identify addiction vulnerability loci in two samples. Proc Natl Acad Sci U S A (2005) 2.00
SNPs, microarrays and pooled DNA: identification of four loci associated with mild mental impairment in a sample of 6000 children. Hum Mol Genet (2005) 1.91
Power and efficiency of the TDT and case-control design for association scans. Behav Genet (2002) 1.75
A central resource for accurate allele frequency estimation from pooled DNA genotyped on DNA microarrays. Nucleic Acids Res (2005) 1.71
Genotyping DNA pools on microarrays: tackling the QTL problem of large samples and large numbers of SNPs. BMC Genomics (2005) 1.68
Whole genome association study of rheumatoid arthritis using 27 039 microsatellites. Hum Mol Genet (2005) 1.36
A simple method for analyzing microsatellite allele image patterns generated from DNA pools and its application to allelic association studies. Am J Hum Genet (1998) 1.29
Streamlined analysis of pooled genotype data in SNP-based association studies. Genet Epidemiol (2005) 1.18
The usefulness of different density SNP maps for disease association studies of common variants. Hum Mol Genet (2003) 1.05
Pooled genotyping of microsatellite markers in parent-offspring trios. Genome Res (2000) 0.97
Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature (2009) 33.26
Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease. Nat Genet (2009) 15.15
Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants. Nat Genet (2007) 12.62
Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls. Nature (2010) 12.27
Identification of loci associated with schizophrenia by genome-wide association and follow-up. Nat Genet (2008) 10.52
Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. Nat Genet (2008) 10.49
Wake-up call for British psychiatry. Br J Psychiatry (2008) 10.30
Genome-wide analysis of genetic loci associated with Alzheimer disease. JAMA (2010) 9.52
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. Nat Genet (2011) 9.23
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet (2013) 8.02
Genome-wide association analysis identifies 13 new risk loci for schizophrenia. Nat Genet (2013) 7.44
Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: Schizophrenia. Am J Hum Genet (2003) 6.63
Microduplications of 16p11.2 are associated with schizophrenia. Nat Genet (2009) 6.13
Gene ontology analysis of GWA study data sets provides insights into the biology of bipolar disorder. Am J Hum Genet (2009) 5.98
Rare chromosomal deletions and duplications in attention-deficit hyperactivity disorder: a genome-wide analysis. Lancet (2010) 5.78
Synaptic, transcriptional and chromatin genes disrupted in autism. Nature (2014) 5.30
Comparative genome hybridization suggests a role for NRXN1 and APBA2 in schizophrenia. Hum Mol Genet (2007) 5.28
Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease. Arch Neurol (2007) 5.09
Support for the involvement of large copy number variants in the pathogenesis of schizophrenia. Hum Mol Genet (2009) 4.52
The beginning of the end for the Kraepelinian dichotomy. Br J Psychiatry (2005) 4.51
The Kraepelinian dichotomy - going, going... but still not gone. Br J Psychiatry (2010) 4.47
Genes for schizophrenia and bipolar disorder? Implications for psychiatric nosology. Schizophr Bull (2005) 3.93
Genes for schizophrenia? Recent findings and their pathophysiological implications. Lancet (2003) 3.61
Discovery and statistical genotyping of copy-number variation from whole-exome sequencing depth. Am J Hum Genet (2012) 3.50
Multiple rare nonsynonymous variants in the adenomatous polyposis coli gene predispose to colorectal adenomas. Cancer Res (2008) 3.49
Genome-wide association identifies a common variant in the reelin gene that increases the risk of schizophrenia only in women. PLoS Genet (2008) 3.33
Cis-acting variation in the expression of a high proportion of genes in human brain. Hum Genet (2003) 3.07
Analysis of copy number variations at 15 schizophrenia-associated loci. Br J Psychiatry (2013) 3.01
Phenotypic and genetic complexity of psychosis. Invited commentary on ... Schizophrenia: a common disease caused by multiple rare alleles. Br J Psychiatry (2007) 2.97
Rethinking psychosis: the disadvantages of a dichotomous classification now outweigh the advantages. World Psychiatry (2007) 2.82
Evidence for novel susceptibility genes for late-onset Alzheimer's disease from a genome-wide association study of putative functional variants. Hum Mol Genet (2007) 2.73
Genome-wide association study identifies genetic variation in neurocan as a susceptibility factor for bipolar disorder. Am J Hum Genet (2011) 2.71
Improved detection of common variants associated with schizophrenia and bipolar disorder using pleiotropy-informed conditional false discovery rate. PLoS Genet (2013) 2.68
Delta-like 1 is necessary for the generation of marginal zone B cells but not T cells in vivo. Nat Immunol (2004) 2.63
Operation of the schizophrenia susceptibility gene, neuregulin 1, across traditional diagnostic boundaries to increase risk for bipolar disorder. Arch Gen Psychiatry (2005) 2.58
Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease. PLoS One (2010) 2.57
Agreement between maternal report and antenatal records for a range of pre and peri-natal factors: the influence of maternal and child characteristics. Early Hum Dev (2006) 2.56
Meta-analysis shows significant association between dopamine system genes and attention deficit hyperactivity disorder (ADHD). Hum Mol Genet (2006) 2.48
Genome-wide analysis of copy number variants in attention deficit hyperactivity disorder: the role of rare variants and duplications at 15q13.3. Am J Psychiatry (2012) 2.48
Paternal age and risk for schizophrenia. Br J Psychiatry (2003) 2.34
Neurexin 1 (NRXN1) deletions in schizophrenia. Schizophr Bull (2009) 2.25
Effects of differential genotyping error rate on the type I error probability of case-control studies. Hum Hered (2006) 2.21
Common variants at VRK2 and TCF4 conferring risk of schizophrenia. Hum Mol Genet (2011) 2.21
Investigating the contribution of common genetic variants to the risk and pathogenesis of ADHD. Am J Psychiatry (2012) 2.20
A genome-wide association study for late-onset Alzheimer's disease using DNA pooling. BMC Med Genomics (2008) 2.20
Risk of psychopathology in adolescent offspring of mothers with psychopathology and recurrent depression. Br J Psychiatry (2012) 2.19
Polymorphism of the 5-HT transporter and response to antidepressants: randomised controlled trial. Br J Psychiatry (2011) 2.18
Genetic variation of brain-derived neurotrophic factor (BDNF) in bipolar disorder: case-control study of over 3000 individuals from the UK. Br J Psychiatry (2006) 2.16
Role of the oxidative DNA damage repair gene OGG1 in colorectal tumorigenesis. J Natl Cancer Inst (2013) 2.13
A haplotype implicated in schizophrenia susceptibility is associated with reduced COMT expression in human brain. Am J Hum Genet (2003) 2.11
Rare copy number variants: a point of rarity in genetic risk for bipolar disorder and schizophrenia. Arch Gen Psychiatry (2010) 2.11
All SNPs are not created equal: genome-wide association studies reveal a consistent pattern of enrichment among functionally annotated SNPs. PLoS Genet (2013) 2.08
Characterization of a family with rare deletions in CNTNAP5 and DOCK4 suggests novel risk loci for autism and dyslexia. Biol Psychiatry (2010) 2.07
Tbx1 haploinsufficiency is linked to behavioral disorders in mice and humans: implications for 22q11 deletion syndrome. Proc Natl Acad Sci U S A (2006) 2.03