Published in J Control Release on July 07, 2010
Liposomes as vaccine delivery systems: a review of the recent advances. Ther Adv Vaccines (2014) 0.93
Polymer-mediated DNA vaccine delivery via bystander cells requires a proper balance between transfection efficiency and cytotoxicity. J Control Release (2011) 0.83
Targeted cytolysins synergistically potentiate cytoplasmic delivery of gelonin immunotoxin. Mol Cancer Ther (2013) 0.82
Listeriolysin O as a strong immunogenic molecule for the development of new anti-tumor vaccines. Hum Vaccin Immunother (2013) 0.80
Conjugation of lipid and CpG-containing oligonucleotide yields an efficient method for liposome incorporation. Bioconjug Chem (2011) 0.79
Journey to the Center of the Cell: Current Nanocarrier Design Strategies Targeting Biopharmaceuticals to the Cytoplasm and Nucleus. Curr Pharm Des (2016) 0.78
Design and characterization of novel recombinant listeriolysin O-protamine fusion proteins for enhanced gene delivery. Mol Pharm (2015) 0.76
Triolein-based polycation lipid nanocarrier for efficient gene delivery: characteristics and mechanism. Int J Nanomedicine (2011) 0.75
Antibody-mediated neutralization of perfringolysin o for intracellular protein delivery. Mol Pharm (2015) 0.75
Phosphorus assay in column chromatography. J Biol Chem (1959) 60.56
LPS/TLR4 signal transduction pathway. Cytokine (2008) 6.60
DNA vaccines: ready for prime time? Nat Rev Genet (2008) 4.10
Nonviral vectors for gene delivery. Chem Rev (2009) 4.08
Induction of antigen-specific cytotoxic T lymphocytes in humans by a malaria DNA vaccine. Science (1998) 3.46
New fluorescent dyes for lymphocyte migration studies. Analysis by flow cytometry and fluorescence microscopy. J Immunol Methods (1990) 3.19
The cell biology of Listeria monocytogenes infection: the intersection of bacterial pathogenesis and cell-mediated immunity. J Cell Biol (2002) 3.01
pH-dependent perforation of macrophage phagosomes by listeriolysin O from Listeria monocytogenes. J Exp Med (1997) 2.26
The prime-boost strategy: exciting prospects for improved vaccination. Immunol Today (2000) 2.03
Improved immunogenicity and protective efficacy of a tuberculosis DNA vaccine encoding Ag85 by protein boosting. Infect Immun (2001) 1.60
DNA vaccination: antigen presentation and the induction of immunity. J Leukoc Biol (2000) 1.60
Development of a xenogeneic DNA vaccine program for canine malignant melanoma at the Animal Medical Center. Vaccine (2005) 1.59
Cutting edge: rapid in vivo CTL activity by polyoma virus-specific effector and memory CD8+ T cells. J Immunol (2003) 1.55
Folate-targeted, anionic liposome-entrapped polylysine-condensed DNA for tumor cell-specific gene transfer. J Biol Chem (1996) 1.55
In vivo gene transfer via intravenous administration of cationic lipid-protamine-DNA (LPD) complexes. Gene Ther (1997) 1.51
Delivery of macromolecules into cytosol using liposomes containing hemolysin from Listeria monocytogenes. J Biol Chem (1996) 1.49
Characterization of cationic lipid-protamine-DNA (LPD) complexes for intravenous gene delivery. Gene Ther (1998) 1.36
Determination of specific CD4 and CD8 T cell epitopes after AAV2- and AAV8-hF.IX gene therapy. Mol Ther (2006) 1.34
Listeriolysin O-liposome-mediated cytosolic delivery of macromolecule antigen in vivo: enhancement of antigen-specific cytotoxic T lymphocyte frequency, activity, and tumor protection. Biochim Biophys Acta (2002) 1.16
Nonviral approaches for targeted delivery of plasmid DNA and oligonucleotide. J Pharm Sci (2008) 1.13
Toll-like receptor 4 plays a crucial role in the immune-adrenal response to systemic inflammatory response syndrome. Proc Natl Acad Sci U S A (2006) 1.08
Efficient intracellular drug and gene delivery using folate receptor-targeted pH-sensitive liposomes composed of cationic/anionic lipid combinations. J Control Release (2002) 1.02
The cell biology of Listeria monocytogenes infection (escape from a vacuole). Ann N Y Acad Sci (1994) 1.02
Enhancement of tumor lysate- and peptide-pulsed dendritic cell-based vaccines by the addition of foreign helper protein. Cancer Res (2001) 1.02
Enhanced gene delivery using disulfide-crosslinked low molecular weight polyethylenimine with listeriolysin o-polyethylenimine disulfide conjugate. J Control Release (2008) 0.97
Liposomes: applications in medicine. J Biomater Appl (2001) 0.97
Plasmid DNA vaccination. Microbes Infect (2005) 0.97
The role of cytotoxic T lymphocytes in infectious disease: history, criteria, and state of the art. Curr Top Microbiol Immunol (1994) 0.93
Cytosolic delivery of antisense oligonucleotides by listeriolysin O-containing liposomes. Gene Ther (2003) 0.92
Lipoplex-induced hemagglutination: potential involvement in intravenous gene delivery. Gene Ther (2002) 0.90
Potent specific immune responses induced by prime-boost-boost strategies based on DNA, adenovirus, and Sendai virus vectors expressing gag gene of Chinese HIV-1 subtype B. Vaccine (2008) 0.88
Augmented humoral and cellular immune responses of a hepatitis B DNA vaccine encoding HBsAg by protein boosting. Vaccine (2005) 0.88
Induction of cytotoxic T-lymphocytes and antitumor activity by a liposomal lipopeptide vaccine. Mol Pharm (2008) 0.88
Pulmonary DNA vaccination: concepts, possibilities and perspectives. J Control Release (2005) 0.87
Enhanced cytosolic delivery of plasmid DNA by a sulfhydryl-activatable listeriolysin O/protamine conjugate utilizing cellular reducing potential. Gene Ther (2003) 0.85
A DNA vaccine prime followed by a liposome-encapsulated protein boost confers enhanced mucosal immune responses and protection. J Immunol (2008) 0.85
Enhanced immunogenicity of an anti-caries vaccine encoding a cell-surface protein antigen of Streptococcus mutans by intranasal DNA prime-protein boost immunization. J Gene Med (2009) 0.82
Critical role for DNA vaccination frequency in induction of antigen-specific cytotoxic responses. Vaccine (2005) 0.82
Augmentation of antigen-specific immune responses using DNA-fusogenic liposome vaccine. Biochem Biophys Res Commun (2004) 0.79
Design of liposomes for circumventing the reticuloendothelial cells. Glycobiology (1991) 0.79
Enhanced plasmid DNA delivery using anionic LPDII by listeriolysin O incorporation. J Gene Med (2005) 0.77
A small step closer to the Holy Grail of DNA vaccines: undisputed clinical benefit in humans. Genome Med (2009) 0.77
A comparison of the growth responses following intramuscular GHRH plasmid administration versus daily growth hormone injections in young pigs. Mol Ther (2009) 0.76
Innate recognition of bacteria by a macrophage cytosolic surveillance pathway. Proc Natl Acad Sci U S A (2002) 3.85
Drug delivery strategy utilizing conjugation via reversible disulfide linkages: role and site of cellular reducing activities. Adv Drug Deliv Rev (2003) 3.25
Properties regulating the nature of the plasmacytoid dendritic cell response to Toll-like receptor 9 activation. J Exp Med (2006) 2.57
A specific gene expression program triggered by Gram-positive bacteria in the cytosol. Proc Natl Acad Sci U S A (2004) 2.10
Comparison of human duodenum and Caco-2 gene expression profiles for 12,000 gene sequences tags and correlation with permeability of 26 drugs. Pharm Res (2002) 1.37
Accelerated macrophage apoptosis induces autoantibody formation and organ damage in systemic lupus erythematosus. J Immunol (2006) 1.28
Identification of a human valacyclovirase: biphenyl hydrolase-like protein as valacyclovir hydrolase. J Biol Chem (2003) 1.19
Listeriolysin O-liposome-mediated cytosolic delivery of macromolecule antigen in vivo: enhancement of antigen-specific cytotoxic T lymphocyte frequency, activity, and tumor protection. Biochim Biophys Acta (2002) 1.16
Modes of calreticulin recruitment to the major histocompatibility complex class I assembly pathway. J Biol Chem (2009) 1.13
Molecular basis of prodrug activation by human valacyclovirase, an alpha-amino acid ester hydrolase. J Biol Chem (2008) 1.04
Enhanced gene delivery using disulfide-crosslinked low molecular weight polyethylenimine with listeriolysin o-polyethylenimine disulfide conjugate. J Control Release (2008) 0.97
Enhancing the intestinal membrane permeability of zanamivir: a carrier mediated prodrug approach. Mol Pharm (2011) 0.96
Localization of protein kinase C epsilon to macrophage vacuoles perforated by Listeria monocytogenes cytolysin. Cell Microbiol (2007) 0.94
Differential cytosolic delivery and presentation of antigen by listeriolysin O-liposomes to macrophages and dendritic cells. Mol Pharm (2005) 0.94
Increasing oral absorption of polar neuraminidase inhibitors: a prodrug transporter approach applied to oseltamivir analogue. Mol Pharm (2013) 0.92
Tumor cell killing enabled by listeriolysin O-liposome-mediated delivery of the protein toxin gelonin. J Biol Chem (2003) 0.89
Chemical and enzymatic stability of amino acid prodrugs containing methoxy, ethoxy and propylene glycol linkers. Mol Pharm (2009) 0.88
Cytosolic delivery of viral nucleoprotein by listeriolysin O-liposome induces enhanced specific cytotoxic T lymphocyte response and protective immunity. Mol Pharm (2004) 0.86
A fluorescent hPept1 transporter substrate for uptake screening. Pharm Res (2003) 0.83
Encapsulating immunostimulatory CpG oligonucleotides in listeriolysin O-liposomes promotes a Th1-type response and CTL activity. Mol Pharm (2012) 0.81
Specificity of a prodrug-activating enzyme hVACVase: the leaving group effect. Mol Pharm (2010) 0.80
Targeting and blocking B7 costimulatory molecules on antigen-presenting cells using CTLA4Ig-conjugated liposomes: in vitro characterization and in vivo factors affecting biodistribution. Pharm Res (2003) 0.79
Conjugation of lipid and CpG-containing oligonucleotide yields an efficient method for liposome incorporation. Bioconjug Chem (2011) 0.79
Delivery of macromolecules into cytosol using liposomes containing hemolysin. Methods Enzymol (2003) 0.79
Enhanced plasmid DNA delivery using anionic LPDII by listeriolysin O incorporation. J Gene Med (2005) 0.77
Cytomegalovirus protease targeted prodrug development. Mol Pharm (2013) 0.77
Mutants of listeriolysin O for enhanced liposomal delivery of macromolecules. J Biotechnol (2013) 0.77
Design and characterization of novel recombinant listeriolysin O-protamine fusion proteins for enhanced gene delivery. Mol Pharm (2015) 0.76
Puromycin-sensitive aminopeptidase: an antiviral prodrug activating enzyme. Antiviral Res (2009) 0.76
Absorbance-based assay for membrane disruption by antimicrobial peptides and synthetic copolymers using pyrroloquinoline quinone-loaded liposomes. Anal Biochem (2011) 0.75
Proline prodrug of melphalan, prophalan-L, demonstrates high therapeutic index in a murine melanoma model. Eur J Pharm Biopharm (2007) 0.75
Thoughts from the frontiers of science: the Gordon Research Conference on Drug Carriers in Medicine and Biology (August 20-25, 2006). Mol Pharm (2006) 0.75
Visual detection of single-stranded target DNA using pyrroloquinoline-quinone-loaded liposomes as a tracer. Anal Biochem (2010) 0.75
Molecular pharmaceutics, a vision for the future. Mol Pharm (2005) 0.75