Published in Anal Biochem on January 13, 2011
Innate recognition of bacteria by a macrophage cytosolic surveillance pathway. Proc Natl Acad Sci U S A (2002) 3.85
Ultrastrong and stiff layered polymer nanocomposites. Science (2007) 3.40
Drug delivery strategy utilizing conjugation via reversible disulfide linkages: role and site of cellular reducing activities. Adv Drug Deliv Rev (2003) 3.25
Studies on anticancer activities of antimicrobial peptides. Biochim Biophys Acta (2007) 3.24
LL-37, the only human member of the cathelicidin family of antimicrobial peptides. Biochim Biophys Acta (2006) 3.05
Properties regulating the nature of the plasmacytoid dendritic cell response to Toll-like receptor 9 activation. J Exp Med (2006) 2.57
A specific gene expression program triggered by Gram-positive bacteria in the cytosol. Proc Natl Acad Sci U S A (2004) 2.10
Membrane thinning due to antimicrobial peptide binding: an atomic force microscopy study of MSI-78 in lipid bilayers. Biophys J (2005) 1.81
Polymers incorporating nitric oxide releasing/generating substances for improved biocompatibility of blood-contacting medical devices. Biomaterials (2005) 1.75
NMR structure of the cathelicidin-derived human antimicrobial peptide LL-37 in dodecylphosphocholine micelles. Biochemistry (2008) 1.65
The human beta-defensin-3, an antibacterial peptide with multiple biological functions. Biochim Biophys Acta (2006) 1.62
Amyloid fiber formation and membrane disruption are separate processes localized in two distinct regions of IAPP, the type-2-diabetes-related peptide. J Am Chem Soc (2008) 1.56
Solid-state NMR reveals structural and dynamical properties of a membrane-anchored electron-carrier protein, cytochrome b5. J Am Chem Soc (2007) 1.53
A partially folded structure of amyloid-beta(1-40) in an aqueous environment. Biochem Biophys Res Commun (2011) 1.51
An innovative procedure using a sublimable solid to align lipid bilayers for solid-state NMR studies. Biophys J (2002) 1.50
Photoinstability of S-nitrosothiols during sampling of whole blood: a likely source of error and variability in S-nitrosothiol measurements. Clin Chem (2008) 1.48
Structures of rat and human islet amyloid polypeptide IAPP(1-19) in micelles by NMR spectroscopy. Biochemistry (2008) 1.47
The cytochromes P450 and b5 and their reductases--promising targets for structural studies by advanced solid-state NMR spectroscopy. Biochim Biophys Acta (2007) 1.47
Membrane disruption and early events in the aggregation of the diabetes related peptide IAPP from a molecular perspective. Acc Chem Res (2011) 1.46
Misfolded proteins in Alzheimer's disease and type II diabetes. Chem Soc Rev (2011) 1.45
The attenuation of platelet and monocyte activation in a rabbit model of extracorporeal circulation by a nitric oxide releasing polymer. Biomaterials (2009) 1.39
Structure and orientation of pardaxin determined by NMR experiments in model membranes. J Biol Chem (2004) 1.38
Comparison of human duodenum and Caco-2 gene expression profiles for 12,000 gene sequences tags and correlation with permeability of 26 drugs. Pharm Res (2002) 1.37
Design of small molecules that target metal-A{beta} species and regulate metal-induced A{beta} aggregation and neurotoxicity. Proc Natl Acad Sci U S A (2010) 1.37
Membrane fragmentation by an amyloidogenic fragment of human Islet Amyloid Polypeptide detected by solid-state NMR spectroscopy of membrane nanotubes. Biochim Biophys Acta (2007) 1.34
The magic of bicelles lights up membrane protein structure. Chem Rev (2012) 1.33
Structure, membrane orientation, mechanism, and function of pexiganan--a highly potent antimicrobial peptide designed from magainin. Biochim Biophys Acta (2008) 1.31
Two-step mechanism of membrane disruption by Aβ through membrane fragmentation and pore formation. Biophys J (2012) 1.31
Small molecule modulators of copper-induced Abeta aggregation. J Am Chem Soc (2009) 1.30
Association of highly compact type II diabetes related islet amyloid polypeptide intermediate species at physiological temperature revealed by diffusion NMR spectroscopy. J Am Chem Soc (2009) 1.29
Accelerated macrophage apoptosis induces autoantibody formation and organ damage in systemic lupus erythematosus. J Immunol (2006) 1.28
Mediation of in vivo glucose sensor inflammatory response via nitric oxide release. J Biomed Mater Res A (2005) 1.28
Heteronuclear isotropic mixing separated local field NMR spectroscopy. J Chem Phys (2006) 1.27
A single mutation in the nonamyloidogenic region of islet amyloid polypeptide greatly reduces toxicity. Biochemistry (2008) 1.27
Time-resolved dehydration-induced structural changes in an intact bovine cortical bone revealed by solid-state NMR spectroscopy. J Am Chem Soc (2009) 1.26
Three-dimensional structure and orientation of rat islet amyloid polypeptide protein in a membrane environment by solution NMR spectroscopy. J Am Chem Soc (2009) 1.26
Nitric oxide releasing silicone rubbers with improved blood compatibility: preparation, characterization, and in vivo evaluation. Biomaterials (2002) 1.25
Induction of negative curvature as a mechanism of cell toxicity by amyloidogenic peptides: the case of islet amyloid polypeptide. J Am Chem Soc (2009) 1.25
Structures of the dimeric and monomeric variants of magainin antimicrobial peptides (MSI-78 and MSI-594) in micelles and bilayers, determined by NMR spectroscopy. Biochemistry (2006) 1.24
Probing the "charge cluster mechanism" in amphipathic helical cationic antimicrobial peptides. Biochemistry (2010) 1.24
Determining the effects of lipophilic drugs on membrane structure by solid-state NMR spectroscopy: the case of the antioxidant curcumin. J Am Chem Soc (2009) 1.24
More lipophilic dialkyldiamine-based diazeniumdiolates: synthesis, characterization, and application in preparing thromboresistant nitric oxide release polymeric coatings. J Med Chem (2003) 1.21
Structure and membrane orientation of IAPP in its natively amidated form at physiological pH in a membrane environment. Biochim Biophys Acta (2011) 1.20
Identification of a human valacyclovirase: biphenyl hydrolase-like protein as valacyclovir hydrolase. J Biol Chem (2003) 1.19
Chemical shift tensor - the heart of NMR: Insights into biological aspects of proteins. Prog Nucl Magn Reson Spectrosc (2010) 1.18
Nitric oxide-releasing hydrophobic polymers: preparation, characterization, and potential biomedical applications. Free Radic Biol Med (2004) 1.18
Conformational preferences of the amylin nucleation site in SDS micelles: an NMR study. Biopolymers (2003) 1.17
The spectrum of antimicrobial activity of the bacteriocin subtilosin A. J Antimicrob Chemother (2007) 1.17
Bicelle-enabled structural studies on a membrane-associated cytochrome B5 by solid-state MAS NMR spectroscopy. Angew Chem Int Ed Engl (2008) 1.17
Listeriolysin O-liposome-mediated cytosolic delivery of macromolecule antigen in vivo: enhancement of antigen-specific cytotoxic T lymphocyte frequency, activity, and tumor protection. Biochim Biophys Acta (2002) 1.16
Site specific interaction of the polyphenol EGCG with the SEVI amyloid precursor peptide PAP(248-286). J Phys Chem B (2012) 1.14
In vivo chemical sensors: tackling biocompatibility. Anal Chem (2006) 1.14
Highly selective optical fluoride ion sensor with submicromolar detection limit based on aluminum(III) octaethylporphyrin in thin polymeric film. J Am Chem Soc (2005) 1.14
Synthetic and natural polycationic polymer nanoparticles interact selectively with fluid-phase domains of DMPC lipid bilayers. Langmuir (2005) 1.13
A model of the membrane-bound cytochrome b5-cytochrome P450 complex from NMR and mutagenesis data. J Biol Chem (2013) 1.12
In vivo biocompatibility and analytical performance of intravascular amperometric oxygen sensors prepared with improved nitric oxide-releasing silicone rubber coating. Anal Chem (2002) 1.12
Insights into antiamyloidogenic properties of the green tea extract (-)-epigallocatechin-3-gallate toward metal-associated amyloid-β species. Proc Natl Acad Sci U S A (2013) 1.12
Implantable chemical sensors for real-time clinical monitoring: progress and challenges. Curr Opin Chem Biol (2002) 1.12
Role of zinc in human islet amyloid polypeptide aggregation. J Am Chem Soc (2010) 1.11
A high-resolution solid-state NMR approach for the structural studies of bicelles. J Am Chem Soc (2006) 1.11
Nitric oxide-releasing biopolymers inhibit thrombus formation in a sheep model of arteriovenous bridge grafts. J Vasc Surg (2004) 1.11
Alternative pathways of human islet amyloid polypeptide aggregation distinguished by (19)f nuclear magnetic resonance-detected kinetics of monomer consumption. Biochemistry (2012) 1.11
Two-dimensional homonuclear chemical shift correlation established by the cross-relaxation driven spin diffusion in solids. J Chem Phys (2008) 1.10
Preparation and characterization of polymeric coatings with combined nitric oxide release and immobilized active heparin. Biomaterials (2005) 1.08
Nitric oxide-releasing fumed silica particles: synthesis, characterization, and biomedical application. J Am Chem Soc (2003) 1.08
Fluoride-selective optical sensor based on aluminum(III)-octaethylporphyrin in thin polymeric film: further characterization and practical application. Anal Chem (2005) 1.08
Rational design of a structural framework with potential use to develop chemical reagents that target and modulate multiple facets of Alzheimer's disease. J Am Chem Soc (2013) 1.07
High-resolution 2D NMR spectroscopy of bicelles to measure the membrane interaction of ligands. J Am Chem Soc (2007) 1.07
Antimicrobial activity and membrane selective interactions of a synthetic lipopeptide MSI-843. Biochim Biophys Acta (2005) 1.07
Delineating metabolic signatures of head and neck squamous cell carcinoma: phospholipase A2, a potential therapeutic target. Int J Biochem Cell Biol (2012) 1.07
Catalytic generation of nitric oxide from S-nitrosothiols using immobilized organoselenium species. Biomaterials (2006) 1.07
Chemical structure of cationic groups in amphiphilic polymethacrylates modulates the antimicrobial and hemolytic activities. Biomacromolecules (2009) 1.07
NMR structure in a membrane environment reveals putative amyloidogenic regions of the SEVI precursor peptide PAP(248-286). J Am Chem Soc (2009) 1.06
Synthesis, characterization, and controlled nitric oxide release from S-nitrosothiol-derivatized fumed silica polymer filler particles. J Biomed Mater Res A (2005) 1.06
Inhibition of amyloid peptide fibrillation by inorganic nanoparticles: functional similarities with proteins. Angew Chem Int Ed Engl (2011) 1.06
Antimicrobial and membrane disrupting activities of a peptide derived from the human cathelicidin antimicrobial peptide LL37. Biophys J (2010) 1.06
Structural determinants of antimicrobial activity and biocompatibility in membrane-disrupting methacrylamide random copolymers. Biomacromolecules (2009) 1.05
NMR structure of pardaxin, a pore-forming antimicrobial peptide, in lipopolysaccharide micelles: mechanism of outer membrane permeabilization. J Biol Chem (2009) 1.05
Helical hairpin structure of a potent antimicrobial peptide MSI-594 in lipopolysaccharide micelles by NMR spectroscopy. Chemistry (2009) 1.04
Nitric oxide releasing polyurethanes with covalently linked diazeniumdiolated secondary amines. Biomacromolecules (2006) 1.04
Molecular basis of prodrug activation by human valacyclovirase, an alpha-amino acid ester hydrolase. J Biol Chem (2008) 1.04
Membrane permeabilization, orientation, and antimicrobial mechanism of subtilosin A. Chem Phys Lipids (2005) 1.03
Probing the spontaneous membrane insertion of a tail-anchored membrane protein by sum frequency generation spectroscopy. J Am Chem Soc (2010) 1.03
Proton-evolved local-field solid-state NMR studies of cytochrome b5 embedded in bicelles, revealing both structural and dynamical information. J Am Chem Soc (2010) 1.03
Natural-abundance 43Ca solid-state NMR spectroscopy of bone. J Am Chem Soc (2010) 1.02