Published in Biophys J on July 21, 2010
Ras trafficking, localization and compartmentalized signalling. Semin Cell Dev Biol (2011) 1.48
Multiple cellular proteins modulate the dynamics of K-ras association with the plasma membrane. Biophys J (2010) 1.19
Membrane clustering and the role of rebinding in biochemical signaling. Biophys J (2012) 1.09
Regulation from within: the cytoskeleton in transmembrane signaling. Trends Cell Biol (2012) 0.99
Signal integration by lipid-mediated spatial cross talk between Ras nanoclusters. Mol Cell Biol (2013) 0.98
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Direct visualization of Ras proteins in spatially distinct cell surface microdomains. J Cell Biol (2003) 5.45
Lipid rafts: contentious only from simplistic standpoints. Nat Rev Mol Cell Biol (2006) 4.94
Galectin-3: an open-ended story. Biochim Biophys Acta (2006) 4.10
Plasma membrane nanoswitches generate high-fidelity Ras signal transduction. Nat Cell Biol (2007) 3.90
H-ras, K-ras, and inner plasma membrane raft proteins operate in nanoclusters with differential dependence on the actin cytoskeleton. Proc Natl Acad Sci U S A (2005) 3.78
Single-molecule imaging analysis of Ras activation in living cells. Proc Natl Acad Sci U S A (2004) 2.84
Activated K-Ras and H-Ras display different interactions with saturable nonraft sites at the surface of live cells. J Cell Biol (2002) 2.62
The dark side of Ras: regulation of apoptosis. Oncogene (2003) 2.60
Galectin-3 precipitates as a pentamer with synthetic multivalent carbohydrates and forms heterogeneous cross-linked complexes. J Biol Chem (2003) 2.27
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Ras plasma membrane signalling platforms. Biochem J (2005) 2.15
Plasma membrane domain organization regulates EGFR signaling in tumor cells. J Cell Biol (2007) 1.82
Identifying optimal lipid raft characteristics required to promote nanoscale protein-protein interactions on the plasma membrane. Mol Cell Biol (2006) 1.81
Galectin-3 augments K-Ras activation and triggers a Ras signal that attenuates ERK but not phosphoinositide 3-kinase activity. J Biol Chem (2004) 1.76
Visualization of galectin-3 oligomerization on the surface of neutrophils and endothelial cells using fluorescence resonance energy transfer. J Biol Chem (2006) 1.73
A quantitative model for the all-or-none permeabilization of phospholipid vesicles by the antimicrobial peptide cecropin A. Biophys J (2007) 1.64
Using plasma membrane nanoclusters to build better signaling circuits. Trends Cell Biol (2008) 1.41
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Electrostatic interactions positively regulate K-Ras nanocluster formation and function. Mol Cell Biol (2008) 1.34
Single-molecule diffusion measurements of H-Ras at the plasma membrane of live cells reveal microdomain localization upon activation. J Cell Sci (2005) 1.34
Sources of anomalous diffusion on cell membranes: a Monte Carlo study. Biophys J (2006) 1.33
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K-ras nanoclustering is subverted by overexpression of the scaffold protein galectin-3. Cancer Res (2008) 1.29
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Lateral compartmentalization of T cell receptor versus CD45 by galectin-N-glycan binding and microfilaments coordinate basal and activation signaling. J Biol Chem (2007) 1.25
Galectin-3 regulates a molecular switch from N-Ras to K-Ras usage in human breast carcinoma cells. Cancer Res (2005) 1.16
Single-molecule diffusion reveals similar mobility for the Lck, H-ras, and K-ras membrane anchors. Biophys J (2006) 1.08
Stochastic model of protein-protein interaction: why signaling proteins need to be colocalized. Proc Natl Acad Sci U S A (2004) 1.04
Spatial modeling of dimerization reaction dynamics in the plasma membrane: Monte Carlo vs. continuum differential equations. Biophys Chem (2006) 1.02
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Direct visualization of Ras proteins in spatially distinct cell surface microdomains. J Cell Biol (2003) 5.45
PTRF-Cavin, a conserved cytoplasmic protein required for caveola formation and function. Cell (2008) 4.42
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GPI-anchored proteins are delivered to recycling endosomes via a distinct cdc42-regulated, clathrin-independent pinocytic pathway. Dev Cell (2002) 4.28
APPL proteins link Rab5 to nuclear signal transduction via an endosomal compartment. Cell (2004) 3.95
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H-ras, K-ras, and inner plasma membrane raft proteins operate in nanoclusters with differential dependence on the actin cytoskeleton. Proc Natl Acad Sci U S A (2005) 3.78
Cells respond to mechanical stress by rapid disassembly of caveolae. Cell (2011) 3.55
Signalling ballet in space and time. Nat Rev Mol Cell Biol (2010) 3.32
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Fld1p, a functional homologue of human seipin, regulates the size of lipid droplets in yeast. J Cell Biol (2008) 2.85
Caveolin-1 is essential for liver regeneration. Science (2006) 2.77
Ultrastructural identification of uncoated caveolin-independent early endocytic vehicles. J Cell Biol (2005) 2.74
Sequence-dependent sorting of recycling proteins by actin-stabilized endosomal microdomains. Cell (2010) 2.67
Activated K-Ras and H-Ras display different interactions with saturable nonraft sites at the surface of live cells. J Cell Biol (2002) 2.62
The Rab5 effector Rabankyrin-5 regulates and coordinates different endocytic mechanisms. PLoS Biol (2004) 2.59
Myosin II isoforms identify distinct functional modules that support integrity of the epithelial zonula adherens. Nat Cell Biol (2010) 2.51
Membrane insertion of anthrax protective antigen and cytoplasmic delivery of lethal factor occur at different stages of the endocytic pathway. J Cell Biol (2004) 2.31
Biogenesis of caveolae: a structural model for caveolin-induced domain formation. J Cell Sci (2006) 2.31
Lipid rafts and membrane traffic. FEBS Lett (2007) 2.25
Individual palmitoyl residues serve distinct roles in H-ras trafficking, microlocalization, and signaling. Mol Cell Biol (2005) 2.24
Regulated localization of Rab18 to lipid droplets: effects of lipolytic stimulation and inhibition of lipid droplet catabolism. J Biol Chem (2005) 2.15
Ras plasma membrane signalling platforms. Biochem J (2005) 2.15
Differential sorting and fate of endocytosed GPI-anchored proteins. EMBO J (2002) 2.15
Cholesterol manipulation by West Nile virus perturbs the cellular immune response. Cell Host Microbe (2007) 2.14
Three separable domains regulate GTP-dependent association of H-ras with the plasma membrane. Mol Cell Biol (2004) 2.09
Not just fat: the structure and function of the lipid droplet. Cold Spring Harb Perspect Biol (2011) 2.07
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A novel switch region regulates H-ras membrane orientation and signal output. EMBO J (2008) 2.06
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Flotillins and the PHB domain protein family: rafts, worms and anaesthetics. Traffic (2005) 2.01
Lipid rafts and plasma membrane microorganization: insights from Ras. Trends Cell Biol (2004) 1.92
Rab23, a negative regulator of hedgehog signaling, localizes to the plasma membrane and the endocytic pathway. Traffic (2003) 1.88
Association of stomatin with lipid bodies. J Biol Chem (2004) 1.88
MURC/Cavin-4 and cavin family members form tissue-specific caveolar complexes. J Cell Biol (2009) 1.87
Clathrin-independent endocytosis: new insights into caveolae and non-caveolar lipid raft carriers. Biochim Biophys Acta (2005) 1.87
Selective stimulation of caveolar endocytosis by glycosphingolipids and cholesterol. Mol Biol Cell (2004) 1.86
Cholesterol and fatty acids regulate dynamic caveolin trafficking through the Golgi complex and between the cell surface and lipid bodies. Mol Biol Cell (2005) 1.86
Hrs and SNX3 functions in sorting and membrane invagination within multivesicular bodies. PLoS Biol (2008) 1.85
Annexin II regulates multivesicular endosome biogenesis in the degradation pathway of animal cells. EMBO J (2003) 1.85
N4WBP5, a potential target for ubiquitination by the Nedd4 family of proteins, is a novel Golgi-associated protein. J Biol Chem (2001) 1.84
Clathrin-independent carriers form a high capacity endocytic sorting system at the leading edge of migrating cells. J Cell Biol (2010) 1.84
On the use of Ripley's K-function and its derivatives to analyze domain size. Biophys J (2009) 1.84
Fsp27 promotes lipid droplet growth by lipid exchange and transfer at lipid droplet contact sites. J Cell Biol (2011) 1.84
Structure and dynamics of the full-length lipid-modified H-Ras protein in a 1,2-dimyristoylglycero-3-phosphocholine bilayer. J Med Chem (2007) 1.84
Clathrin-independent endocytosis: new insights into caveolae and non-caveolar lipid raft carriers. Biochim Biophys Acta (2005) 1.83
Identifying optimal lipid raft characteristics required to promote nanoscale protein-protein interactions on the plasma membrane. Mol Cell Biol (2006) 1.81
Disruption of cooperation between Ras and MycN in human neuroblastoma cells promotes growth arrest. Clin Cancer Res (2005) 1.80
Subcellular localization determines MAP kinase signal output. Curr Biol (2005) 1.78
Lipid droplet-organelle interactions; sharing the fats. Biochim Biophys Acta (2008) 1.77
Galectin-3 augments K-Ras activation and triggers a Ras signal that attenuates ERK but not phosphoinositide 3-kinase activity. J Biol Chem (2004) 1.76
A unique platform for H-Ras signaling involving clathrin-independent endocytosis. Mol Biol Cell (2007) 1.73
Ras inhibition in glioblastoma down-regulates hypoxia-inducible factor-1alpha, causing glycolysis shutdown and cell death. Cancer Res (2005) 1.73
Molecules, mechanisms, and cellular roles of clathrin-independent endocytosis. Curr Opin Cell Biol (2010) 1.70
A role for phosphatidic acid in the formation of "supersized" lipid droplets. PLoS Genet (2011) 1.69
Dynamic microtubules regulate the local concentration of E-cadherin at cell-cell contacts. J Cell Sci (2006) 1.68
Annexin A2-dependent polymerization of actin mediates endosome biogenesis. Dev Cell (2009) 1.67
Cell-to-cell heterogeneity in lipid droplets suggests a mechanism to reduce lipotoxicity. Curr Biol (2013) 1.66
Lysobisphosphatidic acid controls endosomal cholesterol levels. J Biol Chem (2008) 1.62
The GTPase-activating protein GRAF1 regulates the CLIC/GEEC endocytic pathway. Curr Biol (2008) 1.62
Dynamic and regulated association of caveolin with lipid bodies: modulation of lipid body motility and function by a dominant negative mutant. Mol Biol Cell (2003) 1.62
Studies on G-protein alpha.betagamma heterotrimer formation reveal a putative S-prenyl-binding site in the alpha subunit. Biochem J (2003) 1.61
Ras nanoclusters: molecular structure and assembly. Semin Cell Dev Biol (2007) 1.56
H-Ras signaling and K-Ras signaling are differentially dependent on endocytosis. Mol Cell Biol (2002) 1.55
Cholesterol-sensitive Cdc42 activation regulates actin polymerization for endocytosis via the GEEC pathway. Traffic (2007) 1.55
Inhibitors of COP-mediated transport and cholera toxin action inhibit simian virus 40 infection. Mol Biol Cell (2002) 1.53
Galectin-1 augments Ras activation and diverts Ras signals to Raf-1 at the expense of phosphoinositide 3-kinase. J Biol Chem (2002) 1.53
Flotillin-1/reggie-2 traffics to surface raft domains via a novel golgi-independent pathway. Identification of a novel membrane targeting domain and a role for palmitoylation. J Biol Chem (2002) 1.51
Glucose principally regulates insulin secretion in mouse islets by controlling the numbers of granule fusion events per cell. Diabetologia (2013) 1.51
Late endosomal cholesterol accumulation leads to impaired intra-endosomal trafficking. PLoS One (2007) 1.50
Tumor cells secrete galectin-1 to enhance endothelial cell activity. Cancer Res (2010) 1.50
Ras membrane orientation and nanodomain localization generate isoform diversity. Proc Natl Acad Sci U S A (2010) 1.49
High-resolution mapping reveals topologically distinct cellular pools of phosphatidylserine. J Cell Biol (2011) 1.49
A role for oxysterol-binding protein-related protein 5 in endosomal cholesterol trafficking. J Cell Biol (2011) 1.48
A single method for cryofixation and correlative light, electron microscopy and tomography of zebrafish embryos. Traffic (2008) 1.48
Cholesterol-induced caveolin targeting to lipid droplets in adipocytes: a role for caveolar endocytosis. Traffic (2006) 1.48
Ras trafficking, localization and compartmentalized signalling. Semin Cell Dev Biol (2011) 1.48
Review: biogenesis of the multifunctional lipid droplet: lipids, proteins, and sites. J Cell Biol (2014) 1.45
The linker domain of the Ha-Ras hypervariable region regulates interactions with exchange factors, Raf-1 and phosphoinositide 3-kinase. J Biol Chem (2001) 1.44
TNF activates a NF-kappaB-regulated cellular program in human CD45RA- regulatory T cells that modulates their suppressive function. J Immunol (2010) 1.43
A Ras inhibitor tilts the balance between Rac and Rho and blocks phosphatidylinositol 3-kinase-dependent glioblastoma cell migration. Cancer Res (2006) 1.42