Published in Semin Cell Dev Biol on July 17, 2010
Phosphorylation of a membrane curvature-sensing motif switches function of the HOPS subunit Vps41 in membrane tethering. J Cell Biol (2010) 1.34
Cellular uptake and intracellular trafficking of antisense and siRNA oligonucleotides. Bioconjug Chem (2011) 1.32
Rab GTPases implicated in inherited and acquired disorders. Semin Cell Dev Biol (2010) 1.15
Intrinsic tethering activity of endosomal Rab proteins. Nat Struct Mol Biol (2011) 1.02
GTPases in intracellular trafficking: an overview. Semin Cell Dev Biol (2010) 0.93
Clathrin-dependent mechanisms modulate the subcellular distribution of class C Vps/HOPS tether subunits in polarized and nonpolarized cells. Mol Biol Cell (2011) 0.92
Receptors, endocytosis, and trafficking: the biological basis of targeted delivery of antisense and siRNA oligonucleotides. J Drug Target (2012) 0.89
Therapeutic use of botulinum toxin in migraine: mechanisms of action. Br J Pharmacol (2014) 0.88
Apoptosis-linked gene-2 (ALG-2)/Sec31 interactions regulate endoplasmic reticulum (ER)-to-Golgi transport: a potential effector pathway for luminal calcium. J Biol Chem (2014) 0.87
Comparative genomic analysis of multi-subunit tethering complexes demonstrates an ancient pan-eukaryotic complement and sculpting in Apicomplexa. PLoS One (2013) 0.85
Expression of Rab25 correlates with the invasion and metastasis of gastric cancer. Chin J Cancer Res (2013) 0.84
Cellular uptake and intracellular trafficking of oligonucleotides. Adv Drug Deliv Rev (2015) 0.83
The delivery of therapeutic oligonucleotides. Nucleic Acids Res (2016) 0.82
Metazoan cell biology of the HOPS tethering complex. Cell Logist (2011) 0.81
Atg11: a Rab-dependent, coiled-coil membrane protein that acts as a tether for autophagy. Autophagy (2012) 0.80
Rab proteins and the secretory pathway: the case of rab18 in neuroendocrine cells. Front Endocrinol (Lausanne) (2011) 0.80
AP-3 and Rabip4' coordinately regulate spatial distribution of lysosomes. PLoS One (2012) 0.79
The complexity of vesicle transport factors in plants examined by orthology search. PLoS One (2014) 0.78
Mapping the interactions between a RUN domain from DENND5/Rab6IP1 and sorting nexin 1. PLoS One (2012) 0.78
Rab5 and its effector FHF contribute to neuronal polarity through dynein-dependent retrieval of somatodendritic proteins from the axon. Proc Natl Acad Sci U S A (2016) 0.76
SNAREs in the maturation and function of LROs. Bioarchitecture (2016) 0.75
Early stages of functional diversification in the Rab GTPase gene family revealed by genomic and localization studies in Paramecium species. Mol Biol Cell (2017) 0.75
A proteomic approach to identify endosomal cargoes controlling cancer invasiveness. J Cell Sci (2017) 0.75
Arabidopsis RabF1 (ARA6) Is Involved in Salt Stress and Dark-Induced Senescence (DIS). Int J Mol Sci (2017) 0.75
Coat/Tether Interactions-Exception or Rule? Front Cell Dev Biol (2016) 0.75
Sec17 (α-SNAP) and an SM-tethering complex regulate the outcome of SNARE zippering in vitro and in vivo. Elife (2017) 0.75
SNAP receptors implicated in vesicle targeting and fusion. Nature (1993) 18.57
SNAREpins: minimal machinery for membrane fusion. Cell (1998) 16.97
Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 A resolution. Nature (1998) 15.80
Rab GTPases as coordinators of vesicle traffic. Nat Rev Mol Cell Biol (2009) 13.01
BAR domains as sensors of membrane curvature: the amphiphysin BAR structure. Science (2003) 12.60
A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion. Cell (1993) 10.66
COPII: a membrane coat formed by Sec proteins that drive vesicle budding from the endoplasmic reticulum. Cell (1994) 10.01
Endocytosis by random initiation and stabilization of clathrin-coated pits. Cell (2004) 6.75
Coated vesicles from pig brain: purification and biochemical characterization. J Mol Biol (1975) 5.98
Involvement of GTP-binding "G" proteins in transport through the Golgi stack. Cell (1987) 5.28
Compartmental specificity of cellular membrane fusion encoded in SNARE proteins. Nature (2000) 4.67
Purification of a novel class of coated vesicles mediating biosynthetic protein transport through the Golgi stack. Cell (1989) 4.65
Rab1 recruitment of p115 into a cis-SNARE complex: programming budding COPII vesicles for fusion. Science (2000) 4.56
A membrane coat complex essential for endosome-to-Golgi retrograde transport in yeast. J Cell Biol (1998) 4.41
A Ypt/Rab effector complex containing the Sec1 homolog Vps33p is required for homotypic vacuole fusion. Proc Natl Acad Sci U S A (2000) 4.33
The binding of AP-1 clathrin adaptor particles to Golgi membranes requires ADP-ribosylation factor, a small GTP-binding protein. Cell (1993) 4.33
A novel GTP-binding protein, Sar1p, is involved in transport from the endoplasmic reticulum to the Golgi apparatus. J Cell Biol (1989) 4.29
Role of the mammalian retromer in sorting of the cation-independent mannose 6-phosphate receptor. J Cell Biol (2004) 4.24
ADP-ribosylation factor, a small GTP-binding protein, is required for binding of the coatomer protein beta-COP to Golgi membranes. Proc Natl Acad Sci U S A (1992) 4.22
Structural relationships between clathrin assembly proteins from the Golgi and the plasma membrane. EMBO J (1988) 4.06
The Vam6 GEF controls TORC1 by activating the EGO complex. Mol Cell (2009) 4.01
Initial docking of ER-derived vesicles requires Uso1p and Ypt1p but is independent of SNARE proteins. EMBO J (1998) 3.99
Sorting nexin-1 mediates tubular endosome-to-TGN transport through coincidence sensing of high- curvature membranes and 3-phosphoinositides. Curr Biol (2004) 3.76
GRASP65, a protein involved in the stacking of Golgi cisternae. Cell (1997) 3.75
Structure of the Sec23/24-Sar1 pre-budding complex of the COPII vesicle coat. Nature (2002) 3.74
New component of the vacuolar class C-Vps complex couples nucleotide exchange on the Ypt7 GTPase to SNARE-dependent docking and fusion. J Cell Biol (2000) 3.69
Identification and structure of four yeast genes (SLY) that are able to suppress the functional loss of YPT1, a member of the RAS superfamily. Mol Cell Biol (1991) 3.68
SNARE selectivity of the COPII coat. Cell (2003) 3.57
TRAPP, a highly conserved novel complex on the cis-Golgi that mediates vesicle docking and fusion. EMBO J (1998) 3.49
A vacuolar v-t-SNARE complex, the predominant form in vivo and on isolated vacuoles, is disassembled and activated for docking and fusion. J Cell Biol (1998) 3.44
Role of auxilin in uncoating clathrin-coated vesicles. Nature (1995) 3.42
Energetics and dynamics of SNAREpin folding across lipid bilayers. Nat Struct Mol Biol (2007) 3.39
Class C Vps protein complex regulates vacuolar SNARE pairing and is required for vesicle docking/fusion. Mol Cell (2000) 3.30
A novel RING finger protein complex essential for a late step in protein transport to the yeast vacuole. Mol Biol Cell (1997) 3.27
SEC12 encodes a guanine-nucleotide-exchange factor essential for transport vesicle budding from the ER. Nature (1993) 3.23
Biochemical dissection of AP-1 recruitment onto Golgi membranes. J Cell Biol (1993) 3.14
Assembly polypeptides from coated vesicles mediate reassembly of unique clathrin coats. J Cell Biol (1983) 3.06
Binding of coatomer to Golgi membranes requires ADP-ribosylation factor. J Biol Chem (1993) 3.01
Vam3p structure reveals conserved and divergent properties of syntaxins. Nat Struct Biol (2001) 2.92
A role for giantin in docking COPI vesicles to Golgi membranes. J Cell Biol (1998) 2.84
Two new Ypt GTPases are required for exit from the yeast trans-Golgi compartment. J Cell Biol (1997) 2.84
Rab GEFs and GAPs. Curr Opin Cell Biol (2010) 2.73
Role of the AP2 beta-appendage hub in recruiting partners for clathrin-coated vesicle assembly. PLoS Biol (2006) 2.71
Caenorhabditis elegans RME-6 is a novel regulator of RAB-5 at the clathrin-coated pit. Nat Cell Biol (2005) 2.70
A novel 115-kD peripheral membrane protein is required for intercisternal transport in the Golgi stack. J Cell Biol (1992) 2.67
The structural basis for activation of the Rab Ypt1p by the TRAPP membrane-tethering complexes. Cell (2008) 2.61
Novel Golgi to vacuole delivery pathway in yeast: identification of a sorting determinant and required transport component. EMBO J (1997) 2.60
Assembly of the ER to Golgi SNARE complex requires Uso1p. J Cell Biol (1996) 2.57
Rab1 interaction with a GM130 effector complex regulates COPII vesicle cis--Golgi tethering. Traffic (2001) 2.53
Trs85 directs a Ypt1 GEF, TRAPPIII, to the phagophore to promote autophagy. Proc Natl Acad Sci U S A (2010) 2.53
Purification of active HOPS complex reveals its affinities for phosphoinositides and the SNARE Vam7p. EMBO J (2006) 2.52
Hydrolysis of bound GTP by ARF protein triggers uncoating of Golgi-derived COP-coated vesicles. J Cell Biol (1993) 2.51
Sequential tethering of Golgins and catalysis of SNAREpin assembly by the vesicle-tethering protein p115. J Cell Biol (2002) 2.50
Dynamics of the COPII coat with GTP and stable analogues. Nat Cell Biol (2001) 2.44
TRAPPI tethers COPII vesicles by binding the coat subunit Sec23. Nature (2007) 2.42
Coupled ER to Golgi transport reconstituted with purified cytosolic proteins. J Cell Biol (1997) 2.39
A structure-based mechanism for vesicle capture by the multisubunit tethering complex Dsl1. Cell (2009) 2.24
Vps-C complexes: gatekeepers of endolysosomal traffic. Curr Opin Cell Biol (2009) 2.21
TRAPP I implicated in the specificity of tethering in ER-to-Golgi transport. Mol Cell (2001) 2.20
Identification of an adaptor-associated kinase, AAK1, as a regulator of clathrin-mediated endocytosis. J Cell Biol (2002) 2.18
Cryo-electron tomography of clathrin-coated vesicles: structural implications for coat assembly. J Mol Biol (2006) 2.17
Phosphorylation of the AP2 mu subunit by AAK1 mediates high affinity binding to membrane protein sorting signals. J Cell Biol (2002) 2.17
A function for the AP3 coat complex in synaptic vesicle formation from endosomes. Cell (1998) 2.14
The docking stage of yeast vacuole fusion requires the transfer of proteins from a cis-SNARE complex to a Rab/Ypt protein. J Cell Biol (2000) 2.13
Common principles in clathrin-mediated sorting at the Golgi and the plasma membrane. Biochim Biophys Acta (2005) 2.11
The architecture of the multisubunit TRAPP I complex suggests a model for vesicle tethering. Cell (2006) 2.10
The TRAPP complex is a nucleotide exchanger for Ypt1 and Ypt31/32. Mol Biol Cell (2000) 2.05
Regulation of Sar1 NH2 terminus by GTP binding and hydrolysis promotes membrane deformation to control COPII vesicle fission. J Cell Biol (2005) 1.99
The retromer coat complex coordinates endosomal sorting and dynein-mediated transport, with carrier recognition by the trans-Golgi network. Dev Cell (2009) 1.99
Cog3p depletion blocks vesicle-mediated Golgi retrograde trafficking in HeLa cells. J Cell Biol (2005) 1.98
New mutants of Saccharomyces cerevisiae affected in the transport of proteins from the endoplasmic reticulum to the Golgi complex. Genetics (1996) 1.89
ADP-Ribosylation factor 1 (ARF1) regulates recruitment of the AP-3 adaptor complex to membranes. J Cell Biol (1998) 1.89
Asymmetric tethering of flat and curved lipid membranes by a golgin. Science (2008) 1.86
Differential evanescence nanometry: live-cell fluorescence measurements with 10-nm axial resolution on the plasma membrane. Biophys J (2007) 1.85
The vacuolar kinase Yck3 maintains organelle fragmentation by regulating the HOPS tethering complex. J Cell Biol (2005) 1.85
Clathrin self-assembly is mediated by a tandemly repeated superhelix. Nature (1999) 1.84
Sec17p and HOPS, in distinct SNARE complexes, mediate SNARE complex disruption or assembly for fusion. EMBO J (2005) 1.83
COP I domains required for coatomer integrity, and novel interactions with ARF and ARF-GAP. EMBO J (2000) 1.82
Control systems for membrane fusion in the ancestral eukaryote; evolution of tethering complexes and SM proteins. BMC Evol Biol (2007) 1.82
Implication of ZW10 in membrane trafficking between the endoplasmic reticulum and Golgi. EMBO J (2004) 1.82
TRAPPII subunits are required for the specificity switch of a Ypt-Rab GEF. Nat Cell Biol (2006) 1.75
The Sec34/Sec35p complex, a Ypt1p effector required for retrograde intra-Golgi trafficking, interacts with Golgi SNAREs and COPI vesicle coat proteins. J Cell Biol (2002) 1.74
Mutants in trs120 disrupt traffic from the early endosome to the late Golgi. J Cell Biol (2005) 1.71
Formation of AP-3 transport intermediates requires Vps41 function. Nat Cell Biol (1999) 1.69
Efficient termination of vacuolar Rab GTPase signaling requires coordinated action by a GAP and a protein kinase. J Cell Biol (2008) 1.66
Sec35p, a novel peripheral membrane protein, is required for ER to Golgi vesicle docking. J Cell Biol (1998) 1.64
A phosphatidylinositol (4,5)-bisphosphate binding site within mu2-adaptin regulates clathrin-mediated endocytosis. J Cell Biol (2002) 1.62
Secretory cargo regulates the turnover of COPII subunits at single ER exit sites. Curr Biol (2006) 1.60
A functional phosphatidylinositol 3,4,5-trisphosphate/phosphoinositide binding domain in the clathrin adaptor AP-2 alpha subunit. Implications for the endocytic pathway. J Biol Chem (1996) 1.58
Clathrin coats at 21 A resolution: a cellular assembly designed to recycle multiple membrane receptors. EMBO J (1998) 1.56
Minimal membrane docking requirements revealed by reconstitution of Rab GTPase-dependent membrane fusion from purified components. Proc Natl Acad Sci U S A (2009) 1.55
mTrs130 is a component of a mammalian TRAPPII complex, a Rab1 GEF that binds to COPI-coated vesicles. Mol Biol Cell (2009) 1.55
Golgin tethers define subpopulations of COPI vesicles. Science (2005) 1.54
COPI vesicles accumulating in the presence of a GTP restricted arf1 mutant are depleted of anterograde and retrograde cargo. J Cell Sci (2000) 1.50
HOPS initiates vacuole docking by tethering membranes before trans-SNARE complex assembly. Mol Biol Cell (2010) 1.48
Gene replacement reveals that p115/SNARE interactions are essential for Golgi biogenesis. Proc Natl Acad Sci U S A (2004) 1.47
Trans-SNARE complex assembly and yeast vacuole membrane fusion. Proc Natl Acad Sci U S A (2007) 1.46
Hermansky-Pudlak syndrome protein complexes associate with phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells. J Biol Chem (2008) 1.45
Capture and release of partially zipped trans-SNARE complexes on intact organelles. J Cell Biol (2009) 1.45
En bloc incorporation of coatomer subunits during the assembly of COP-coated vesicles. J Cell Biol (1994) 1.42
A type VI secretion system of Pseudomonas aeruginosa targets a toxin to bacteria. Cell Host Microbe (2010) 4.98
Vacuole fusion at a ring of vertex docking sites leaves membrane fragments within the organelle. Cell (2002) 2.55
Vps-C complexes: gatekeepers of endolysosomal traffic. Curr Opin Cell Biol (2009) 2.21
Interdependent assembly of specific regulatory lipids and membrane fusion proteins into the vertex ring domain of docked vacuoles. J Cell Biol (2004) 2.08
Hierarchy of protein assembly at the vertex ring domain for yeast vacuole docking and fusion. J Cell Biol (2003) 1.92
Efficient termination of vacuolar Rab GTPase signaling requires coordinated action by a GAP and a protein kinase. J Cell Biol (2008) 1.66
A soluble SNARE drives rapid docking, bypassing ATP and Sec17/18p for vacuole fusion. EMBO J (2004) 1.65
A cycle of Vam7p release from and PtdIns 3-P-dependent rebinding to the yeast vacuole is required for homotypic vacuole fusion. J Cell Biol (2002) 1.62
Capture and release of partially zipped trans-SNARE complexes on intact organelles. J Cell Biol (2009) 1.45
Subunit organization and Rab interactions of Vps-C protein complexes that control endolysosomal membrane traffic. Mol Biol Cell (2011) 1.35
Sec1/Munc18 protein Vps33 binds to SNARE domains and the quaternary SNARE complex. Mol Biol Cell (2012) 1.20
PilT is required for PI(3,4,5)P3-mediated crosstalk between Neisseria gonorrhoeae and epithelial cells. Cell Microbiol (2005) 1.20
HOPS interacts with Apl5 at the vacuole membrane and is required for consumption of AP-3 transport vesicles. Mol Biol Cell (2009) 1.16
Intrinsic tethering activity of endosomal Rab proteins. Nat Struct Mol Biol (2011) 1.02
Osmotic regulation of Rab-mediated organelle docking. Curr Biol (2008) 0.93
The prototypical H+/galactose symporter GalP assembles into functional trimers. J Mol Biol (2009) 0.92
Vps9 family protein Muk1 is the second Rab5 guanosine nucleotide exchange factor in budding yeast. J Biol Chem (2013) 0.91
Rho signaling participates in membrane fluidity homeostasis. PLoS One (2012) 0.87