Published in Nature on September 14, 2000
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Early/recycling endosomes-to-TGN transport involves two SNARE complexes and a Rab6 isoform. J Cell Biol (2002) 3.36
SNARE proteins are required for macroautophagy. Cell (2011) 2.99
Single molecule observation of liposome-bilayer fusion thermally induced by soluble N-ethyl maleimide sensitive-factor attachment protein receptors (SNAREs). Biophys J (2004) 2.75
Legionella subvert the functions of Rab1 and Sec22b to create a replicative organelle. J Exp Med (2004) 2.67
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Determinants of liposome fusion mediated by synaptic SNARE proteins. Proc Natl Acad Sci U S A (2004) 2.28
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Distinct SNARE complexes mediating membrane fusion in Golgi transport based on combinatorial specificity. Proc Natl Acad Sci U S A (2002) 2.07
Interactions between syntaxins identify at least five SNARE complexes within the Golgi/prevacuolar system of the Arabidopsis cell. Mol Biol Cell (2001) 2.05
Yeast Cdc42 functions at a late step in exocytosis, specifically during polarized growth of the emerging bud. J Cell Biol (2001) 1.94
Sec1p directly stimulates SNARE-mediated membrane fusion in vitro. J Cell Biol (2004) 1.94
Sly1 protein bound to Golgi syntaxin Sed5p allows assembly and contributes to specificity of SNARE fusion complexes. J Cell Biol (2002) 1.92
SNARE-mediated lipid mixing depends on the physical state of the vesicles. Biophys J (2005) 1.91
Alpha-synuclein delays endoplasmic reticulum (ER)-to-Golgi transport in mammalian cells by antagonizing ER/Golgi SNAREs. Mol Biol Cell (2010) 1.89
Sporulation in the budding yeast Saccharomyces cerevisiae. Genetics (2011) 1.88
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Yeast homotypic vacuole fusion requires the Ccz1-Mon1 complex during the tethering/docking stage. J Cell Biol (2003) 1.81
Complexin cross-links prefusion SNAREs into a zigzag array. Nat Struct Mol Biol (2011) 1.81
SNAREs can promote complete fusion and hemifusion as alternative outcomes. J Cell Biol (2005) 1.78
Autophagy in yeast: mechanistic insights and physiological function. Microbiol Mol Biol Rev (2001) 1.78
The Sec1p/Munc18 protein Vps45p binds its cognate SNARE proteins via two distinct modes. J Cell Biol (2006) 1.76
Molecular basis for the sorting of the SNARE VAMP7 into endocytic clathrin-coated vesicles by the ArfGAP Hrb. Cell (2008) 1.75
Disruption of individual members of Arabidopsis syntaxin gene families indicates each has essential functions. Plant Cell (2001) 1.74
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A fast, single-vesicle fusion assay mimics physiological SNARE requirements. Proc Natl Acad Sci U S A (2010) 1.68
A soluble SNARE drives rapid docking, bypassing ATP and Sec17/18p for vacuole fusion. EMBO J (2004) 1.65
SGR2, a phospholipase-like protein, and ZIG/SGR4, a SNARE, are involved in the shoot gravitropism of Arabidopsis. Plant Cell (2002) 1.63
An effector of Ypt6p binds the SNARE Tlg1p and mediates selective fusion of vesicles with late Golgi membranes. EMBO J (2001) 1.62
Homotypic fusion of early endosomes: SNAREs do not determine fusion specificity. Proc Natl Acad Sci U S A (2006) 1.59
Review series: Rab GTPases and membrane identity: causal or inconsequential? J Cell Biol (2013) 1.56
Functional characterization of the KNOLLE-interacting t-SNARE AtSNAP33 and its role in plant cytokinesis. J Cell Biol (2001) 1.56
Single-molecule studies of the neuronal SNARE fusion machinery. Annu Rev Biochem (2009) 1.55
Homotypic fusion of immature secretory granules during maturation requires syntaxin 6. Mol Biol Cell (2001) 1.52
Asymmetric phospholipid distribution drives in vitro reconstituted SNARE-dependent membrane fusion. Proc Natl Acad Sci U S A (2006) 1.51
The abscisic acid-related SNARE homolog NtSyr1 contributes to secretion and growth: evidence from competition with its cytosolic domain. Plant Cell (2002) 1.44
The Schizosaccharomyces pombe spo3+ gene is required for assembly of the forespore membrane and genetically interacts with psy1(+)-encoding syntaxin-like protein. Mol Biol Cell (2001) 1.43
Countercurrent distribution of two distinct SNARE complexes mediating transport within the Golgi stack. Mol Biol Cell (2004) 1.39
A SNARE complex unique to seed plants is required for protein storage vacuole biogenesis and seed development of Arabidopsis thaliana. Plant Cell (2008) 1.38
A conformational switch in complexin is required for synaptotagmin to trigger synaptic fusion. Nat Struct Mol Biol (2011) 1.37
Munc18a scaffolds SNARE assembly to promote membrane fusion. Mol Biol Cell (2008) 1.36
Participation of the syntaxin 5/Ykt6/GS28/GS15 SNARE complex in transport from the early/recycling endosome to the trans-Golgi network. Mol Biol Cell (2004) 1.36
A t-SNARE of the endocytic pathway must be activated for fusion. J Cell Biol (2001) 1.36
Regulation of early endosomal entry by the Drosophila tumor suppressors Rabenosyn and Vps45. Mol Biol Cell (2008) 1.34
Syntaxins 3 and 4 are concentrated in separate clusters on the plasma membrane before the establishment of cell polarity. Mol Biol Cell (2005) 1.32
Apical targeting of syntaxin 3 is essential for epithelial cell polarity. J Cell Biol (2006) 1.32
Early endosomal SNAREs form a structurally conserved SNARE complex and fuse liposomes with multiple topologies. EMBO J (2006) 1.30
A role of complexin-lipid interactions in membrane fusion. FEBS Lett (2009) 1.30
MARCH-II is a syntaxin-6-binding protein involved in endosomal trafficking. Mol Biol Cell (2005) 1.30
A random mutagenesis approach to isolate dominant-negative yeast sec1 mutants reveals a functional role for domain 3a in yeast and mammalian Sec1/Munc18 proteins. Genetics (2008) 1.29
Localization and activity of the SNARE Ykt6 determined by its regulatory domain and palmitoylation. Proc Natl Acad Sci U S A (2004) 1.28
Selective formation of Sed5p-containing SNARE complexes is mediated by combinatorial binding interactions. Mol Biol Cell (2001) 1.28
The SM protein Car/Vps33A regulates SNARE-mediated trafficking to lysosomes and lysosome-related organelles. Mol Biol Cell (2009) 1.27
Membrane trafficking. The specificity of vesicle traffic to the Golgi is encoded in the golgin coiled-coil proteins. Science (2014) 1.26
The specificity of SNARE-dependent fusion is encoded in the SNARE motif. Proc Natl Acad Sci U S A (2004) 1.23
VAMP8 is the v-SNARE that mediates basolateral exocytosis in a mouse model of alcoholic pancreatitis. J Clin Invest (2008) 1.23
Autophagic substrate clearance requires activity of the syntaxin-5 SNARE complex. J Cell Sci (2011) 1.23
Sequential SNARE disassembly and GATE-16-GOS-28 complex assembly mediated by distinct NSF activities drives Golgi membrane fusion. J Cell Biol (2002) 1.20
The SNARE Ykt6 mediates protein palmitoylation during an early stage of homotypic vacuole fusion. EMBO J (2003) 1.19
Sec18p and Vam7p remodel trans-SNARE complexes to permit a lipid-anchored R-SNARE to support yeast vacuole fusion. EMBO J (2007) 1.19
Ric1p and the Ypt6p GTPase function in a common pathway required for localization of trans-Golgi network membrane proteins. Mol Biol Cell (2001) 1.18
Membrane fusion by the GTPase atlastin requires a conserved C-terminal cytoplasmic tail and dimerization through the middle domain. Proc Natl Acad Sci U S A (2011) 1.18
Generation of nonidentical compartments in vesicular transport systems. J Cell Biol (2005) 1.17
Role of microtubules in fusion of post-Golgi vesicles to the plasma membrane. Mol Biol Cell (2003) 1.17
t-SNARE dephosphorylation promotes SNARE assembly and exocytosis in yeast. EMBO J (2001) 1.16
The secretory system of Arabidopsis. Arabidopsis Book (2008) 1.16
Medicago truncatula syntaxin SYP132 defines the symbiosome membrane and infection droplet membrane in root nodules. Planta (2006) 1.15
RINT-1 regulates the localization and entry of ZW10 to the syntaxin 18 complex. Mol Biol Cell (2006) 1.15
i-SNAREs: inhibitory SNAREs that fine-tune the specificity of membrane fusion. J Cell Biol (2003) 1.14
Differential use of endoplasmic reticulum membrane for phagocytosis in J774 macrophages. Proc Natl Acad Sci U S A (2005) 1.12
The Tlg SNARE complex is required for TGN homotypic fusion. J Cell Biol (2001) 1.11
Secretory protein biogenesis and traffic in the early secretory pathway. Genetics (2013) 1.11
Intracellular bacteria encode inhibitory SNARE-like proteins. PLoS One (2009) 1.10
Pathways for antigen cross presentation. Springer Semin Immunopathol (2004) 1.10
AtVPS45 is a positive regulator of the SYP41/SYP61/VTI12 SNARE complex involved in trafficking of vacuolar cargo. Plant Physiol (2009) 1.10
The role of syntaxins in the specificity of vesicle targeting in polarized epithelial cells. Mol Biol Cell (2005) 1.09
The identification of a novel endoplasmic reticulum to Golgi SNARE complex used by the prechylomicron transport vesicle. J Biol Chem (2006) 1.08
Legionella pneumophila promotes functional interactions between plasma membrane syntaxins and Sec22b. Traffic (2010) 1.08
SNAREs: cogs and coordinators in signaling and development. Plant Physiol (2008) 1.08
New links between vesicle coats and Rab-mediated vesicle targeting. Semin Cell Dev Biol (2010) 1.07
The COG complex interacts directly with Syntaxin 6 and positively regulates endosome-to-TGN retrograde transport. J Cell Biol (2011) 1.07
The Sec1p/Munc18 (SM) protein, Vps45p, cycles on and off membranes during vesicle transport. J Cell Biol (2003) 1.06
Hepatocyte polarity. Compr Physiol (2013) 1.06
Members of the synaptobrevin/vesicle-associated membrane protein (VAMP) family in Drosophila are functionally interchangeable in vivo for neurotransmitter release and cell viability. Proc Natl Acad Sci U S A (2002) 1.06
SM proteins Sly1 and Vps33 co-assemble with Sec17 and SNARE complexes to oppose SNARE disassembly by Sec18. Elife (2014) 1.05
Expression of Ebolavirus glycoprotein on the target cells enhances viral entry. Virol J (2009) 1.04
The N-terminal domain of the t-SNARE Vam3p coordinates priming and docking in yeast vacuole fusion. Mol Biol Cell (2001) 1.03
Identification of the neuroblastoma-amplified gene product as a component of the syntaxin 18 complex implicated in Golgi-to-endoplasmic reticulum retrograde transport. Mol Biol Cell (2009) 1.03
CF45-1, a secreted protein which participates in Dictyostelium group size regulation. Eukaryot Cell (2003) 1.03
SNAP25, but not syntaxin 1A, recycles via an ARF6-regulated pathway in neuroendocrine cells. Mol Biol Cell (2005) 1.03
Tubulin is the endogenous inhibitor of the glyceraldehyde 3-phosphate dehydrogenase isoform that catalyzes membrane fusion: Implications for the coordinated regulation of glycolysis and membrane fusion. Proc Natl Acad Sci U S A (2002) 1.03
The Legionella pneumophila effector DrrA is sufficient to stimulate SNARE-dependent membrane fusion. Cell Host Microbe (2012) 1.03
Resolving the function of distinct Munc18-1/SNARE protein interaction modes in a reconstituted membrane fusion assay. J Biol Chem (2011) 1.02
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