The expression profile of the major mouse SPO11 isoforms indicates that SPO11beta introduces double strand breaks and suggests that SPO11alpha has an additional role in prophase in both spermatocytes and oocytes.

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Published in Mol Cell Biol on July 20, 2010

Authors

Marina A Bellani1, Kingsley A Boateng, Dianne McLeod, R Daniel Camerini-Otero

Author Affiliations

1: Genetics and Biochemistry Branch, NIDDK, NIH, Bethesda, MD 20892, USA.

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