Published in Nature on April 03, 2011
5-Hydroxymethylcytosine is associated with enhancers and gene bodies in human embryonic stem cells. Genome Biol (2011) 3.48
A fine-scale chimpanzee genetic map from population sequencing. Science (2012) 2.83
Genetic recombination is directed away from functional genomic elements in mice. Nature (2012) 2.46
Fine-scale heterogeneity in crossover rate in the garnet-scalloped region of the Drosophila melanogaster X chromosome. Genetics (2013) 2.17
Meiotic recombination in mammals: localization and regulation. Nat Rev Genet (2013) 2.00
MAnorm: a robust model for quantitative comparison of ChIP-Seq data sets. Genome Biol (2012) 1.88
Mouse PRDM9 DNA-binding specificity determines sites of histone H3 lysine 4 trimethylation for initiation of meiotic recombination. PLoS Biol (2011) 1.73
Epigenetic conservation at gene regulatory elements revealed by non-methylated DNA profiling in seven vertebrates. Elife (2013) 1.63
The Landscape of Mouse Meiotic Double-Strand Break Formation, Processing, and Repair. Cell (2016) 1.49
The recombination landscape in Arabidopsis thaliana F2 populations. Heredity (Edinb) (2011) 1.42
Genetic recombination is targeted towards gene promoter regions in dogs. PLoS Genet (2013) 1.35
Arabidopsis meiotic crossover hot spots overlap with H2A.Z nucleosomes at gene promoters. Nat Genet (2013) 1.29
Mechanistic basis of infertility of mouse intersubspecific hybrids. Proc Natl Acad Sci U S A (2013) 1.20
The impressionistic landscape of meiotic recombination. Cell (2011) 1.18
The case of the fickle fingers: how the PRDM9 zinc finger protein specifies meiotic recombination hotspots in humans. PLoS Biol (2011) 1.15
Mechanism and regulation of meiotic recombination initiation. Cold Spring Harb Perspect Biol (2014) 1.13
The genomic landscape of meiotic crossovers and gene conversions in Arabidopsis thaliana. Elife (2013) 1.12
Transposable elements as genetic regulatory substrates in early development. Trends Cell Biol (2013) 1.12
PRDM9 binding organizes hotspot nucleosomes and limits Holliday junction migration. Genome Res (2014) 1.12
Epigenetic remodeling of meiotic crossover frequency in Arabidopsis thaliana DNA methyltransferase mutants. PLoS Genet (2012) 1.11
Latent regulatory potential of human-specific repetitive elements. Mol Cell (2012) 1.08
Sensitive mapping of recombination hotspots using sequencing-based detection of ssDNA. Genome Res (2012) 1.07
Normalization of ChIP-seq data with control. BMC Bioinformatics (2012) 1.06
Recombination regulator PRDM9 influences the instability of its own coding sequence in humans. Proc Natl Acad Sci U S A (2012) 1.02
PRDM9 drives evolutionary erosion of hotspots in Mus musculus through haplotype-specific initiation of meiotic recombination. PLoS Genet (2015) 1.02
Crossovers are associated with mutation and biased gene conversion at recombination hotspots. Proc Natl Acad Sci U S A (2015) 1.00
Genetics and evolution of hybrid male sterility in house mice. Genetics (2012) 1.00
Fine-scale maps of recombination rates and hotspots in the mouse genome. Genetics (2012) 0.99
Integrated transcriptome analysis of mouse spermatogenesis. BMC Genomics (2014) 0.98
High-resolution sex-specific linkage maps of the mouse reveal polarized distribution of crossovers in male germline. Genetics (2014) 0.97
Acetylated Histone H3K9 is associated with meiotic recombination hotspots, and plays a role in recombination redundantly with other factors including the H3K4 methylase Set1 in fission yeast. Nucleic Acids Res (2013) 0.96
Diversity of Prdm9 zinc finger array in wild mice unravels new facets of the evolutionary turnover of this coding minisatellite. PLoS One (2014) 0.95
The histone chaperone Spt6 is required for activation-induced cytidine deaminase target determination through H3K4me3 regulation. J Biol Chem (2012) 0.95
Evolutionarily diverse determinants of meiotic DNA break and recombination landscapes across the genome. Genome Res (2014) 0.94
The juxtaparanodal proteins CNTNAP2 and TAG1 regulate diet-induced obesity. Mamm Genome (2012) 0.93
Recombination rates and genomic shuffling in human and chimpanzee--a new twist in the chromosomal speciation theory. Mol Biol Evol (2012) 0.91
Differential expression and sex chromosome association of CHD3/4 and CHD5 during spermatogenesis. PLoS One (2014) 0.91
Meiotic development in Caenorhabditis elegans. Adv Exp Med Biol (2013) 0.90
The DSIF subunits Spt4 and Spt5 have distinct roles at various phases of immunoglobulin class switch recombination. PLoS Genet (2012) 0.90
Recombination in the human Pseudoautosomal region PAR1. PLoS Genet (2014) 0.89
Trimethylation of histone H3 lysine 36 by human methyltransferase PRDM9 protein. J Biol Chem (2014) 0.89
Contrasted patterns of crossover and non-crossover at Arabidopsis thaliana meiotic recombination hotspots. PLoS Genet (2013) 0.89
DNA methylation restrains transposons from adopting a chromatin signature permissive for meiotic recombination. Genes Dev (2015) 0.89
Population demographic history can cause the appearance of recombination hotspots. Am J Hum Genet (2012) 0.87
Multimer Formation Explains Allelic Suppression of PRDM9 Recombination Hotspots. PLoS Genet (2015) 0.87
Preaching about the converted: how meiotic gene conversion influences genomic diversity. Ann N Y Acad Sci (2012) 0.85
Crossover heterogeneity in the absence of hotspots in Caenorhabditis elegans. Genetics (2013) 0.85
The red queen model of recombination hotspots evolution in the light of archaic and modern human genomes. PLoS Genet (2014) 0.84
Variation in genome-wide levels of meiotic recombination is established at the onset of prophase in mammalian males. PLoS Genet (2014) 0.84
The evolutionary turnover of recombination hot spots contributes to speciation in mice. Genes Dev (2016) 0.83
The role of retrotransposons in gene family expansions: insights from the mouse Abp gene family. BMC Evol Biol (2013) 0.82
Genetic recombination variation in wild Robertsonian mice: on the role of chromosomal fusions and Prdm9 allelic background. Proc Biol Sci (2014) 0.81
The Genetic Architecture of Natural Variation in Recombination Rate in Drosophila melanogaster. PLoS Genet (2016) 0.81
Local and sex-specific biases in crossover vs. noncrossover outcomes at meiotic recombination hot spots in mice. Genes Dev (2015) 0.81
The conserved histone deacetylase Rpd3 and its DNA binding subunit Ume6 control dynamic transcript architecture during mitotic growth and meiotic development. Nucleic Acids Res (2014) 0.81
Recombining without Hotspots: A Comprehensive Evolutionary Portrait of Recombination in Two Closely Related Species of Drosophila. Genome Biol Evol (2015) 0.81
Multiple LINEs of retrotransposon silencing mechanisms in the mammalian germline. Semin Cell Dev Biol (2016) 0.81
Topological Data Analysis Generates High-Resolution, Genome-wide Maps of Human Recombination. Cell Syst (2016) 0.80
Finding the correct partner: the meiotic courtship. Scientifica (Cairo) (2012) 0.80
LDsplit: screening for cis-regulatory motifs stimulating meiotic recombination hotspots by analysis of DNA sequence polymorphisms. BMC Bioinformatics (2014) 0.80
Dynamics of rye chromosome 1R regions with high or low crossover frequency in homology search and synapsis development. PLoS One (2012) 0.79
Local chromosome context is a major determinant of crossover pathway biochemistry during budding yeast meiosis. Elife (2016) 0.79
Analysis of biological features associated with meiotic recombination hot and cold spots in Saccharomyces cerevisiae. PLoS One (2011) 0.79
New paradigms for conserved, multifactorial, cis-acting regulation of meiotic recombination. Nucleic Acids Res (2012) 0.79
Crossing-over in a hypervariable species preferentially occurs in regions of high local similarity. Mol Biol Evol (2014) 0.79
Extreme recombination frequencies shape genome variation and evolution in the honeybee, Apis mellifera. PLoS Genet (2015) 0.79
Meiotic DSB patterning: A multifaceted process. Cell Cycle (2016) 0.79
Affinity-seq detects genome-wide PRDM9 binding sites and reveals the impact of prior chromatin modifications on mammalian recombination hotspot usage. Epigenetics Chromatin (2015) 0.79
Initiation of meiotic homologous recombination: flexibility, impact of histone modifications, and chromatin remodeling. Cold Spring Harb Perspect Biol (2015) 0.79
Repression of harmful meiotic recombination in centromeric regions. Semin Cell Dev Biol (2016) 0.79
Incomplete meiotic sex chromosome inactivation in the domestic dog. BMC Genomics (2015) 0.78
The roles of microRNAs and siRNAs in mammalian spermatogenesis. Development (2016) 0.78
DNA Crossover Motifs Associated with Epigenetic Modifications Delineate Open Chromatin Regions in Arabidopsis. Plant Cell (2015) 0.78
Strong heterogeneity in mutation rate causes misleading hallmarks of natural selection on indel mutations in the human genome. Mol Biol Evol (2013) 0.78
Exposure to the widely used herbicide atrazine results in deregulation of global tissue-specific RNA transcription in the third generation and is associated with a global decrease of histone trimethylation in mice. Nucleic Acids Res (2016) 0.77
Control of Meiotic Crossovers: From Double-Strand Break Formation to Designation. Annu Rev Genet (2016) 0.77
Recombination patterns in maize reveal limits to crossover homeostasis. Proc Natl Acad Sci U S A (2015) 0.77
Suppression of Meiotic Recombination by CENP-B Homologs in Schizosaccharomyces pombe. Genetics (2015) 0.77
The complex binding of PRDM9. Genome Biol (2013) 0.77
Epigenetic functions enriched in transcription factors binding to mouse recombination hotspots. Proteome Sci (2012) 0.77
Low levels of LTR retrotransposon deletion by ectopic recombination in the gigantic genomes of salamanders. J Mol Evol (2015) 0.77
The epigenetic processes of meiosis in male mice are broadly affected by the widely used herbicide atrazine. BMC Genomics (2015) 0.76
SPoRE: a mathematical model to predict double strand breaks and axis protein sites in meiosis. BMC Bioinformatics (2014) 0.76
The Double-Strand Break Landscape of Meiotic Chromosomes Is Shaped by the Paf1 Transcription Elongation Complex in Saccharomyces cerevisiae. Genetics (2015) 0.76
Meiotic DSBs and the control of mammalian recombination. Cell Res (2012) 0.76
Spatiotemporal regulation of meiotic recombination by Liaisonin. Bioarchitecture (2013) 0.76
Suppression of genetic recombination in the pseudoautosomal region and at subtelomeres in mice with a hypomorphic Spo11 allele. BMC Genomics (2013) 0.76
Understanding and manipulating meiotic recombination in plants. Plant Physiol (2017) 0.75
High-Resolution Mapping of Crossover and Non-crossover Recombination Events by Whole-Genome Re-sequencing of an Avian Pedigree. PLoS Genet (2016) 0.75
X marks the spot: PRDM9 rescues hybrid sterility by finding hidden treasure in the genome. Nat Struct Mol Biol (2016) 0.75
Functional Roles of Acetylated Histone Marks at Mouse Meiotic Recombination Hotspots. Mol Cell Biol (2016) 0.75
PRDM9 interactions with other proteins provide a link between recombination hotspots and the chromosomal axis in meiosis. Mol Biol Cell (2016) 0.75
Chromatin architecture may dictate the target site for DMC1, but not for RAD51, during homologous pairing. Sci Rep (2016) 0.75
hotspot: software to support sperm-typing for investigating recombination hotspots. Bioinformatics (2016) 0.75
H4K44 Acetylation Facilitates Chromatin Accessibility during Meiosis. Cell Rep (2015) 0.75
Specific modifications of histone tails, but not DNA methylation, mirror the temporal variation of mammalian recombination hotspots. Genome Biol Evol (2014) 0.75
Novel H3K4me3 marks are enriched at human- and chimpanzee-specific cytogenetic structures. Genome Res (2014) 0.75
Finding trans-regulatory genes and protein complexes modulating meiotic recombination hotspots of human, mouse and yeast. BMC Syst Biol (2014) 0.75
In vivo binding of PRDM9 reveals interactions with noncanonical genomic sites. Genome Res (2017) 0.75
Activation-Induced Cytidine Deaminase Does Not Impact Murine Meiotic Recombination. G3 (Bethesda) (2013) 0.75
A map of human genome variation from population-scale sequencing. Nature (2010) 121.13
A haplotype map of the human genome. Nature (2005) 105.70
A second generation human haplotype map of over 3.1 million SNPs. Nature (2007) 85.39
A fine-scale map of recombination rates and hotspots across the human genome. Science (2005) 26.82
The DNA-encoded nucleosome organization of a eukaryotic genome. Nature (2008) 11.41
PRDM9 is a major determinant of meiotic recombination hotspots in humans and mice. Science (2009) 8.72
A common sequence motif associated with recombination hot spots and genome instability in humans. Nat Genet (2008) 8.64
Drive against hotspot motifs in primates implicates the PRDM9 gene in meiotic recombination. Science (2009) 7.35
Prdm9 controls activation of mammalian recombination hotspots. Science (2009) 7.02
A mouse speciation gene encodes a meiotic histone H3 methyltransferase. Science (2008) 5.35
Fine-scale recombination rate differences between sexes, populations and individuals. Nature (2010) 4.74
Biased gene conversion and the evolution of mammalian genomic landscapes. Annu Rev Genomics Hum Genet (2009) 4.12
Distinct histone modifications define initiation and repair of meiotic recombination in the mouse. EMBO J (2009) 3.47
Histone H3 lysine 4 trimethylation marks meiotic recombination initiation sites. EMBO J (2008) 3.40
PRDM9 variation strongly influences recombination hot-spot activity and meiotic instability in humans. Nat Genet (2010) 3.33
Clarifying the mechanics of DNA strand exchange in meiotic recombination. Nature (2006) 3.02
Genetic homology and crossing over in the X and Y chromosomes of Mammals. Hum Genet (1982) 2.89
A new standard genetic map for the laboratory mouse. Genetics (2009) 2.78
The recombinational anatomy of a mouse chromosome. PLoS Genet (2008) 2.66
Mammalian recombination hot spots: properties, control and evolution. Nat Rev Genet (2010) 2.54
Characterization of human epigenomes. Curr Opin Genet Dev (2009) 2.17
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Mammalian meiotic recombination hot spots. Annu Rev Genet (2007) 1.90
The Hop2 protein has a direct role in promoting interhomolog interactions during mouse meiosis. Dev Cell (2003) 1.64
Playing hide and seek with mammalian meiotic crossover hotspots. Trends Genet (2007) 1.54
Analysis of meiotic recombination products from human sperm. Methods Mol Biol (2009) 1.04
Ea recombinational hot spot in the mouse major histocompatibility complex maps to the fourth intron of the Ea gene. Genome Res (1996) 1.01
Mouse strains with an active H2-Ea meiotic recombination hot spot exhibit increased levels of H2-Ea-specific DNA breaks in testicular germ cells. Mol Cell Biol (2004) 0.98
Contrasting methods of quantifying fine structure of human recombination. Annu Rev Genomics Hum Genet (2010) 0.95
Genomic instability in mice lacking histone H2AX. Science (2002) 10.23
DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1. Nat Cell Biol (2002) 5.85
The mouse X chromosome is enriched for sex-biased genes not subject to selection by meiotic sex chromosome inactivation. Nat Genet (2004) 4.62
Role of Nbs1 in the activation of the Atm kinase revealed in humanized mouse models. Nat Cell Biol (2005) 3.44
H2AX is required for chromatin remodeling and inactivation of sex chromosomes in male mouse meiosis. Dev Cell (2003) 3.42
Genetic recombination is directed away from functional genomic elements in mice. Nature (2012) 2.46
Homologous pairing preceding SPO11-mediated double-strand breaks in mice. Dev Cell (2013) 1.96
Mediation of CTCF transcriptional insulation by DEAD-box RNA-binding protein p68 and steroid receptor RNA activator SRA. Genes Dev (2010) 1.88
The Hop2 and Mnd1 proteins act in concert with Rad51 and Dmc1 in meiotic recombination. Nat Struct Mol Biol (2005) 1.73
SPO11 is required for sex-body formation, and Spo11 heterozygosity rescues the prophase arrest of Atm-/- spermatocytes. J Cell Sci (2005) 1.73
Over 1000 genes are involved in the DNA damage response of Escherichia coli. Mol Microbiol (2002) 1.72
Bipartite stimulatory action of the Hop2-Mnd1 complex on the Rad51 recombinase. Genes Dev (2007) 1.67
The Hop2 protein has a direct role in promoting interhomolog interactions during mouse meiosis. Dev Cell (2003) 1.64
Tuberoinfundibular Peptide of 39 residues is required for germ cell development. Endocrinology (2008) 1.55
MDC1 directs chromosome-wide silencing of the sex chromosomes in male germ cells. Genes Dev (2011) 1.52
Hop2/Mnd1 acts on two critical steps in Dmc1-promoted homologous pairing. Genes Dev (2007) 1.51
Characterization of the DNA damage-inducible helicase DinG from Escherichia coli. J Biol Chem (2003) 1.27
Molecular activities of meiosis-specific proteins Hop2, Mnd1, and the Hop2-Mnd1 complex. J Biol Chem (2006) 1.25
The expression profile of the major mouse SPO11 isoforms indicates that SPO11beta introduces double strand breaks and suggests that SPO11alpha has an additional role in prophase in both spermatocytes and oocytes. Mol Cell Biol (2010) 1.23
A dominant, recombination-defective allele of Dmc1 causing male-specific sterility. PLoS Biol (2007) 1.19
The DinI protein stabilizes RecA protein filaments. J Biol Chem (2004) 1.18
The DinG protein from Escherichia coli is a structure-specific helicase. J Biol Chem (2007) 1.13
Rsx is a metatherian RNA with Xist-like properties in X-chromosome inactivation. Nature (2012) 1.08
Sensitive mapping of recombination hotspots using sequencing-based detection of ssDNA. Genome Res (2012) 1.07
Stimulation of fission yeast and mouse Hop2-Mnd1 of the Dmc1 and Rad51 recombinases. Nucleic Acids Res (2007) 1.06
Crystal structure of the Escherichia coli YcdX protein reveals a trinuclear zinc active site. Proteins (2003) 1.06
Analysis of a mesoscopic stochastic model of microtubule dynamic instability. Phys Rev E Stat Nonlin Soft Matter Phys (2006) 1.04
FANCJ helicase uniquely senses oxidative base damage in either strand of duplex DNA and is stimulated by replication protein A to unwind the damaged DNA substrate in a strand-specific manner. J Biol Chem (2009) 1.04
Phosphorylation of chromosome core components may serve as axis marks for the status of chromosomal events during mammalian meiosis. PLoS Genet (2012) 0.99
BRCA1-mediated chromatin silencing is limited to oocytes with a small number of asynapsed chromosomes. J Cell Sci (2009) 0.98
X for intersection: retrotransposition both on and off the X chromosome is more frequent. Trends Genet (2005) 0.98
The mechanisms of microtubule catastrophe and rescue: implications from analysis of a dimer-scale computational model. Mol Biol Cell (2011) 0.98
The resistance of DMC1 D-loops to dissociation may account for the DMC1 requirement in meiosis. Nat Struct Mol Biol (2010) 0.97
Crystal structure of Escherichia coli protein ybgI, a toroidal structure with a dinuclear metal site. BMC Struct Biol (2003) 0.96
Detecting sequence polymorphisms associated with meiotic recombination hotspots in the human genome. Genome Biol (2010) 0.92
Origins of new male germ-line functions from X-derived autosomal retrogenes in the mouse. Mol Biol Evol (2007) 0.91
Genetic crossovers are predicted accurately by the computed human recombination map. PLoS Genet (2010) 0.90
Mechanistic insights into the role of Hop2-Mnd1 in meiotic homologous DNA pairing. Nucleic Acids Res (2013) 0.89
Vezf1 protein binding sites genome-wide are associated with pausing of elongating RNA polymerase II. Proc Natl Acad Sci U S A (2012) 0.89
The dual role of HOP2 in mammalian meiotic homologous recombination. Nucleic Acids Res (2013) 0.88
Homologous recombination and RecA protein: towards a new generation of tools for genome manipulations. Trends Biotechnol (2005) 0.87
Hop2-Mnd1 condenses DNA to stimulate the synapsis phase of DNA strand exchange. Biophys J (2010) 0.86
Molecular features and functional constraints in the evolution of the mammalian X chromosome. Crit Rev Biochem Mol Biol (2005) 0.85
Synaptic complex revisited; a homologous recombinase flips and switches bases. Mol Cell (2004) 0.84
Crystal structure of the Escherichia coli YjiA protein suggests a GTP-dependent regulatory function. Proteins (2004) 0.82
Influence of DNA sequence on the positioning of RecA monomers in RecA-DNA cofilaments. J Biol Chem (2001) 0.82
Gene expression profiles of Spo11-/- mouse testes with spermatocytes arrested in meiotic prophase I. Reproduction (2006) 0.82
Reversibility, equilibration, and fidelity of strand exchange reaction between short oligonucleotides promoted by RecA protein from escherichia coli and human Rad51 and Dmc1 proteins. J Biol Chem (2008) 0.81
Revisiting the Plasmodium falciparum RIFIN family: from comparative genomics to 3D-model prediction. BMC Genomics (2009) 0.80
Dynamics of response to asynapsis and meiotic silencing in spermatocytes from Robertsonian translocation carriers. PLoS One (2013) 0.77
Phasing of RecA monomers on quasi-random DNA sequences. FEBS Lett (2003) 0.76
Suppression of genetic recombination in the pseudoautosomal region and at subtelomeres in mice with a hypomorphic Spo11 allele. BMC Genomics (2013) 0.76
Using computational modeling to understand microtubule dynamics: A primer for cell biologists. Methods Cell Biol (2010) 0.75
Erratum: The evolutionary turnover of recombination hot spots contributes to speciation in mice. Genes Dev (2016) 0.75
Crystal structure of the Escherichia coli Tas protein, an NADP(H)-dependent aldo-keto reductase. Proteins (2003) 0.75