Published in Chembiochem on August 16, 2010
Identification of the biosynthetic gene cluster for the pacidamycin group of peptidyl nucleoside antibiotics. Proc Natl Acad Sci U S A (2010) 1.42
Nine enzymes are required for assembly of the pacidamycin group of peptidyl nucleoside antibiotics. J Am Chem Soc (2011) 1.04
Biosynthesis of the tunicamycin antibiotics proceeds via unique exo-glycal intermediates. Nat Chem (2012) 0.99
tRNA-dependent peptide bond formation by the transferase PacB in biosynthesis of the pacidamycin group of pentapeptidyl nucleoside antibiotics. Proc Natl Acad Sci U S A (2011) 0.99
Characterization of LipL as a non-heme, Fe(II)-dependent α-ketoglutarate:UMP dioxygenase that generates uridine-5'-aldehyde during A-90289 biosynthesis. J Biol Chem (2011) 0.99
Characterization of the amicetin biosynthesis gene cluster from Streptomyces vinaceusdrappus NRRL 2363 implicates two alternative strategies for amide bond formation. Appl Environ Microbiol (2012) 0.95
Biosynthesis of albomycin δ(2) provides a template for assembling siderophore and aminoacyl-tRNA synthetase inhibitor conjugates. ACS Chem Biol (2012) 0.95
Biosynthetic origin and mechanism of formation of the aminoribosyl moiety of peptidyl nucleoside antibiotics. J Am Chem Soc (2011) 0.91
Pleiotropic regulatory genes bldA, adpA and absB are implicated in production of phosphoglycolipid antibiotic moenomycin. Open Biol (2013) 0.87
SsaA, a member of a novel class of transcriptional regulators, controls sansanmycin production in Streptomyces sp. strain SS through a feedback mechanism. J Bacteriol (2013) 0.87
The regulation and biosynthesis of antimycins. Beilstein J Org Chem (2013) 0.87
Chemical logic and enzymatic machinery for biological assembly of peptidyl nucleoside antibiotics. ACS Chem Biol (2011) 0.86
Natural and engineered biosynthesis of nucleoside antibiotics in Actinomycetes. J Ind Microbiol Biotechnol (2015) 0.84
MbtH homology codes to identify gifted microbes for genome mining. J Ind Microbiol Biotechnol (2013) 0.79
Characterization of biosynthetic genes of ascamycin/dealanylascamycin featuring a 5'-O-sulfonamide moiety in Streptomyces sp. JCM9888. PLoS One (2014) 0.79
Streptomyces lividans blasticidin S deaminase and its application in engineering a blasticidin S-producing strain for ease of genetic manipulation. Appl Environ Microbiol (2013) 0.78
Revealing the first uridyl peptide antibiotic biosynthetic gene cluster and probing pacidamycin biosynthesis. Bioeng Bugs (2011) 0.77
Sansanmycin natural product analogues as potent and selective anti-mycobacterials that inhibit lipid I biosynthesis. Nat Commun (2017) 0.76
Identification of novel mureidomycin analogues via rational activation of a cryptic gene cluster in Streptomyces roseosporus NRRL 15998. Sci Rep (2015) 0.75
Crystallization and preliminary X-ray analysis of Pac17 from the pacidamycin-biosynthetic cluster of Streptomyces coeruleorubidus. Acta Crystallogr Sect F Struct Biol Cryst Commun (2012) 0.75
Improving the N-terminal diversity of sansanmycin through mutasynthesis. Microb Cell Fact (2016) 0.75
Living GenoChemetics by hyphenating synthetic biology and synthetic chemistry in vivo. Nat Commun (2017) 0.75
Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338. Nat Biotechnol (2007) 3.45
Antimicrobial nucleoside antibiotics targeting cell wall assembly: recent advances in structure-function studies and nucleoside biosynthesis. Nat Prod Rep (2009) 1.92
A mixed community of actinomycetes produce multiple antibiotics for the fungus farming ant Acromyrmex octospinosus. BMC Biol (2010) 1.66
A single Streptomyces symbiont makes multiple antifungals to support the fungus farming ant Acromyrmex octospinosus. PLoS One (2011) 1.23
A serine carboxypeptidase-like acyltransferase is required for synthesis of antimicrobial compounds and disease resistance in oats. Plant Cell (2009) 1.15
Enzymatic assembly of the bis-indole core of rebeccamycin. J Am Chem Soc (2006) 1.08
Gene expression enabling synthetic diversification of natural products: chemogenetic generation of pacidamycin analogs. J Am Chem Soc (2010) 1.07
The saponins: polar isoprenoids with important and diverse biological activities. Nat Prod Rep (2011) 0.98
Scope and potential of halogenases in biosynthetic applications. Curr Opin Chem Biol (2013) 0.92
New pacidamycin antibiotics through precursor-directed biosynthesis. Chembiochem (2009) 0.91
The first one-pot synthesis of L-7-iodotryptophan from 7-iodoindole and serine, and an improved synthesis of other L-7-halotryptophans. Org Lett (2014) 0.87
Biogenesis of the unique 4',5'-dehydronucleoside of the uridyl peptide antibiotic pacidamycin. J Am Chem Soc (2011) 0.85
Glycosyltransferases from oat (Avena) implicated in the acylation of avenacins. J Biol Chem (2012) 0.85
Synthesis of potential early-stage intermediates in the biosynthesis of FR900482 and mitomycin C. Org Lett (2009) 0.85
Exploiting the reaction flexibility of a type III polyketide synthase through in vitro pathway manipulation. J Am Chem Soc (2005) 0.83
Development of fluorescent aryltryptophans by Pd mediated cross-coupling of unprotected halotryptophans in water. Chem Commun (Camb) (2008) 0.82
Structural characterization of the mitomycin 7-O-methyltransferase. Proteins (2011) 0.82
A convenient one-step synthesis of L-aminotryptophans and improved synthesis of 5-fluorotryptophan. Bioorg Med Chem Lett (2008) 0.81
Isolating antifungals from fungus-growing ant symbionts using a genome-guided chemistry approach. Methods Enzymol (2012) 0.81
Assay for the enantiomeric analysis of [2H1]-fluoroacetic acid: insight into the stereochemical course of fluorination during fluorometabolite biosynthesis in streptomyces cattleya. J Am Chem Soc (2003) 0.80
Engineering biofilms for biocatalysis. Chembiochem (2011) 0.80
Extreme enantiomeric discrimination of fluoroalkanes using deuterium NMR in chiral liquid crystalline media. Chem Commun (Camb) (2002) 0.79
Mechanism of action of the uridyl peptide antibiotics: an unexpected link to a protein-protein interaction site in translocase MraY. Chem Commun (Camb) (2014) 0.79
Characterisation of spin coated engineered Escherichia coli biofilms using atomic force microscopy. Colloids Surf B Biointerfaces (2011) 0.79
Molecular analysis of the role of tyrosine 224 in the active site of Streptomyces coelicolor RppA, a bacterial type III polyketide synthase. J Biol Chem (2007) 0.78
Catalytically active tetramodular 6-deoxyerythonolide B synthase fusion proteins. Chembiochem (2003) 0.77
New pacidamycins biosynthetically: probing N- and C-terminal substrate specificity. Org Biomol Chem (2010) 0.77
Total synthesis of chloptosin: a dimeric cyclohexapeptide. Chemistry (2011) 0.77
Revealing the first uridyl peptide antibiotic biosynthetic gene cluster and probing pacidamycin biosynthesis. Bioeng Bugs (2011) 0.77
Crystallization and preliminary X-ray analysis of Pac17 from the pacidamycin-biosynthetic cluster of Streptomyces coeruleorubidus. Acta Crystallogr Sect F Struct Biol Cryst Commun (2012) 0.75
Highlights from the 46th EUCHEM Conference on stereochemistry, Bürgenstock, Switzerland, May 2011. Chem Commun (Camb) (2011) 0.75