Published in J Am Chem Soc on March 18, 2011
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Dynamic thiolation-thioesterase structure of a non-ribosomal peptide synthetase. Nature (2008) 2.39
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Mass spectrometric characterization of human histone H3: a bird's eye view. J Proteome Res (2006) 2.29
Combinatorial modification of human histone H4 quantitated by two-dimensional liquid chromatography coupled with top down mass spectrometry. J Biol Chem (2008) 2.28
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Thirteen posttranslational modifications convert a 14-residue peptide into the antibiotic thiocillin. Proc Natl Acad Sci U S A (2009) 2.22
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Discovery and in vitro biosynthesis of haloduracin, a two-component lantibiotic. Proc Natl Acad Sci U S A (2006) 2.19
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Negative regulation of NF-kappaB action by Set9-mediated lysine methylation of the RelA subunit. EMBO J (2009) 2.05
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Selective translocation of intracellular Smoothened to the primary cilium in response to Hedgehog pathway modulation. Proc Natl Acad Sci U S A (2009) 2.04
Genetically encoded short peptide tag for versatile protein labeling by Sfp phosphopantetheinyl transferase. Proc Natl Acad Sci U S A (2005) 2.03
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Characterization of the two-protein complex in Escherichia coli responsible for lipopolysaccharide assembly at the outer membrane. Proc Natl Acad Sci U S A (2010) 1.85
Labeling proteins with small molecules by site-specific posttranslational modification. J Am Chem Soc (2004) 1.84
Tissue-specific expression and post-translational modification of histone H3 variants. J Proteome Res (2008) 1.84
The structure of VibH represents nonribosomal peptide synthetase condensation, cyclization and epimerization domains. Nat Struct Biol (2002) 1.82
Robust in vitro activity of RebF and RebH, a two-component reductase/halogenase, generating 7-chlorotryptophan during rebeccamycin biosynthesis. Proc Natl Acad Sci U S A (2005) 1.82
Site-specific protein labeling by Sfp phosphopantetheinyl transferase. Nat Protoc (2006) 1.82
Convergence of isoprene and polyketide biosynthetic machinery: isoprenyl-S-carrier proteins in the pksX pathway of Bacillus subtilis. Proc Natl Acad Sci U S A (2006) 1.80
Design and stereoselective preparation of a new class of chiral olefin metathesis catalysts and application to enantioselective synthesis of quebrachamine: catalyst development inspired by natural product synthesis. J Am Chem Soc (2009) 1.77
Lacticin 481 synthetase phosphorylates its substrate during lantibiotic production. J Am Chem Soc (2005) 1.76
Yersiniabactin synthetase: a four-protein assembly line producing the nonribosomal peptide/polyketide hybrid siderophore of Yersinia pestis. Chem Biol (2002) 1.75
A transglutaminase homologue as a condensation catalyst in antibiotic assembly lines. Nature (2007) 1.74
Unusual transformations in the biosynthesis of the antibiotic phosphinothricin tripeptide. Nat Chem Biol (2007) 1.72
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Complete protein characterization using top-down mass spectrometry and ultraviolet photodissociation. J Am Chem Soc (2013) 1.69
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A robust two-dimensional separation for top-down tandem mass spectrometry of the low-mass proteome. J Am Soc Mass Spectrom (2009) 1.65
Processing complex mixtures of intact proteins for direct analysis by mass spectrometry. Anal Chem (2002) 1.63
Mass spectrometric interrogation of thioester-bound intermediates in the initial stages of epothilone biosynthesis. Chem Biol (2004) 1.61
Top-down proteomics on a chromatographic time scale using linear ion trap fourier transform hybrid mass spectrometers. Anal Chem (2007) 1.60
The genetic and molecular basis for sunscreen biosynthesis in cyanobacteria. Science (2010) 1.59
Dichlorination of a pyrrolyl-S-carrier protein by FADH2-dependent halogenase PltA during pyoluteorin biosynthesis. Proc Natl Acad Sci U S A (2005) 1.58
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Top down mass spectrometry of < 60-kDa proteins from Methanosarcina acetivorans using quadrupole FRMS with automated octopole collisionally activated dissociation. Mol Cell Proteomics (2006) 1.57
Assembling the glycopeptide antibiotic scaffold: The biosynthesis of A47934 from Streptomyces toyocaensis NRRL15009. Proc Natl Acad Sci U S A (2002) 1.57
Hydroxymalonyl-acyl carrier protein (ACP) and aminomalonyl-ACP are two additional type I polyketide synthase extender units. Proc Natl Acad Sci U S A (2006) 1.56