Serotonin transporter gene associations with psychopathic traits in youth vary as a function of socioeconomic resources.

PubWeight™: 1.06‹?› | Rank: Top 15%

🔗 View Article (PMC 2916190)

Published in J Abnorm Psychol on August 01, 2010

Authors

Naomi Sadeh1, Shabnam Javdani, Joshua J Jackson, Elizabeth K Reynolds, Marc N Potenza, Joel Gelernter, C W Lejuez, Edelyn Verona

Author Affiliations

1: Department of Psychology, University of Illinois at Urbana-Champaign, 603 East Daniel Street, Champaign, IL 61820, USA. nsamimi2@illinois.edu

Articles citing this

The neurobiology of psychopathic traits in youths. Nat Rev Neurosci (2013) 1.67

Interactions between serotonin transporter gene haplotypes and quality of mothers' parenting predict the development of children's noncompliance. Dev Psychol (2011) 1.12

Antisocial behaviour in children with and without callous-unemotional traits. J R Soc Med (2012) 1.09

5-HTTLPR as a potential moderator of the effects of adverse childhood experiences on risk of antisocial personality disorder. Psychiatr Genet (2011) 1.05

The other allele: exploring the long allele of the serotonin transporter gene as a potential risk factor for psychopathy: a review of the parallels in findings. Neurosci Biobehav Rev (2010) 0.97

Genetic associations with performance on a behavioral measure of distress intolerance. J Psychiatr Res (2011) 0.93

Understanding Youth Antisocial Behavior Using Neuroscience through a Developmental Psychopathology Lens: Review, Integration, and Directions for Research. Dev Rev (2013) 0.92

Biological contributions to addictions in adolescents and adults: prevention, treatment, and policy implications. J Adolesc Health (2013) 0.91

Environmental risk, Oxytocin Receptor Gene (OXTR) methylation and youth callous-unemotional traits: a 13-year longitudinal study. Mol Psychiatry (2014) 0.90

The Texas Twin Project. Twin Res Hum Genet (2012) 0.89

Callous-unemotional traits as a cross-disorders construct. Soc Psychiatry Psychiatr Epidemiol (2012) 0.89

A preliminary examination of how serotonergic polymorphisms influence brain response following an adolescent cannabis intervention. Psychiatry Res (2012) 0.84

Ringleader bullying: association with psychopathic narcissism and theory of mind among child psychiatric inpatients. Child Psychiatry Hum Dev (2013) 0.80

An exploration of the serotonin system in antisocial boys with high levels of callous-unemotional traits. PLoS One (2013) 0.80

Genetics of callous-unemotional behavior in children. PLoS One (2013) 0.80

Differential impact of serotonin transporter activity on temperament and behavior in persons with a family history of alcoholism in the Oklahoma Family Health Patterns Project. Alcohol Clin Exp Res (2014) 0.79

Interaction between serotonin transporter and serotonin receptor 1 B genes polymorphisms may be associated with antisocial alcoholism. Behav Brain Funct (2012) 0.79

A Preliminary Examination of the Relationship Between the 5-HTTLPR and Childhood Emotional Abuse on Depressive Symptoms in 10-12-Year-Old Youth. Psychol Trauma (2014) 0.78

How and why does the 5-HTTLPR gene moderate associations between maternal unresponsiveness and children's disruptive problems? Child Dev (2013) 0.78

Community Violence Exposure and Callous-Unemotional Traits in Adolescents: Testing Parental Support as a Promotive Versus Protective Factor. Pers Individ Dif (2015) 0.78

Underlying Mechanisms of Gene-Environment Interactions in Externalizing Behavior: A Systematic Review and Search for Theoretical Mechanisms. Clin Child Fam Psychol Rev (2015) 0.77

Genetic moderation of interpersonal psychotherapy efficacy for low-income mothers with major depressive disorder: implications for differential susceptibility. Dev Psychopathol (2015) 0.77

Aggression traits in youth psychopathy: the key role of serotonin. Front Psychiatry (2014) 0.76

The Inventory of Callous-Unemotional Traits (ICU) in Children: Reliability and Heritability. Behav Genet (2016) 0.75

Serotonin 1B Receptor Gene (HTR1B) Methylation as a Risk Factor for Callous-Unemotional Traits in Antisocial Boys. PLoS One (2015) 0.75

Psychopathic traits mediate the association of serotonin transporter genotype and child externalizing behavior. Aggress Behav (2016) 0.75

Can the Five Factor Model of Personality Account for the Variability of Autism Symptom Expression? Multivariate Approaches to Behavioral Phenotyping in Adult Autism Spectrum Disorder. J Autism Dev Disord (2016) 0.75

The Development of Severe and Chronic Violence Among Youth: The Role of Psychopathic Traits and Reward Processing. Child Psychiatry Hum Dev (2017) 0.75

Articles cited by this

Role of genotype in the cycle of violence in maltreated children. Science (2002) 13.50

Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression: a meta-analysis. JAMA (2009) 12.35

Biological sensitivity to context: I. An evolutionary-developmental theory of the origins and functions of stress reactivity. Dev Psychopathol (2005) 5.55

Genetic structure, self-identified race/ethnicity, and confounding in case-control association studies. Am J Hum Genet (2004) 4.51

A susceptibility gene for affective disorders and the response of the human amygdala. Arch Gen Psychiatry (2005) 4.33

Long story short: the serotonin transporter in emotion regulation and social cognition. Nat Neurosci (2007) 3.66

Psychopathic traits and conduct problems in community and clinic-referred samples of children: further development of the psychopathy screening device. Psychol Assess (2000) 3.45

Serotonin transporter protein (SLC6A4) allele and haplotype frequencies and linkage disequilibria in African- and European-American and Japanese populations and in alcohol-dependent subjects. Hum Genet (1997) 2.88

Emotion in the criminal psychopath: startle reflex modulation. J Abnorm Psychol (1993) 2.59

Beyond affect: a role for genetic variation of the serotonin transporter in neural activation during a cognitive attention task. Proc Natl Acad Sci U S A (2005) 2.24

Genetic variation in the serotonin transporter promoter region affects serotonin uptake in human blood platelets. Am J Med Genet (1999) 2.16

Callous-unemotional traits in a community sample of adolescents. Assessment (2006) 2.09

Gene-environment interactions in depression research: genetic polymorphisms and life-stress polyprocedures. Psychol Sci (2008) 1.91

Serotonergic mechanisms promote dominance acquisition in adult male vervet monkeys. Brain Res (1991) 1.65

Association between serotonin transporter gene and borderline personality disorder. J Psychiatr Res (2006) 1.64

New evidence for an association between the CSF HVA:5-HIAA ratio and psychopathic traits. J Neurol Neurosurg Psychiatry (2003) 1.58

Variation of human amygdala response during threatening stimuli as a function of 5'HTTLPR genotype and personality style. Biol Psychiatry (2005) 1.55

Heritability for adolescent antisocial behavior differs with socioeconomic status: gene-environment interaction. J Child Psychol Psychiatry (2006) 1.54

The 4 year stability of psychopathic traits in non-referred youth. Behav Sci Law (2003) 1.41

The Nature (and Nurture?) of Plasticity in Early Human Development. Perspect Psychol Sci (2009) 1.36

Impulsivity, aggression, and serotonin: a molecular psychobiological perspective. Behav Sci Law (2000) 1.28

Relations of serotonin function to personality: current views and a key methodological issue. Psychiatry Res (2006) 1.15

CSF studies in violent offenders. I. 5-HIAA as a negative and HVA as a positive predictor of psychopathy. J Neural Transm (Vienna) (2001) 1.11

Serotonin transporter polymorphisms and persistent, pervasive childhood aggression. Am J Psychiatry (2006) 1.08

Family-based association test of the 5HTTLPR and aggressive behavior in a general population sample of children. Biol Psychiatry (2006) 0.98

The relationship between serotonergic function and the Psychopathy Checklist: Screening Version. J Psychopharmacol (2003) 0.92

Articles by these authors

Developmental neurocircuitry of motivation in adolescence: a critical period of addiction vulnerability. Am J Psychiatry (2003) 7.11

Can food be addictive? Public health and policy implications. Addiction (2011) 6.27

Impulse control disorders in Parkinson disease: a cross-sectional study of 3090 patients. Arch Neurol (2010) 4.77

Synonymous mutations in the human dopamine receptor D2 (DRD2) affect mRNA stability and synthesis of the receptor. Hum Mol Genet (2003) 4.63

Distress tolerance and duration of past smoking cessation attempts. J Abnorm Psychol (2002) 4.52

Social supports and serotonin transporter gene moderate depression in maltreated children. Proc Natl Acad Sci U S A (2004) 4.42

Brain-derived neurotrophic factor-5-HTTLPR gene interactions and environmental modifiers of depression in children. Biol Psychiatry (2006) 3.97

Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD. PLoS Genet (2010) 3.91

A functional polymorphism of the mu-opioid receptor gene is associated with naltrexone response in alcohol-dependent patients. Neuropsychopharmacology (2003) 3.66

Behavioral impulsivity predicts treatment outcome in a smoking cessation program for adolescent smokers. Drug Alcohol Depend (2006) 3.61

Compulsive features in behavioural addictions: the case of pathological gambling. Addiction (2011) 3.28

Introduction to behavioral addictions. Am J Drug Alcohol Abuse (2010) 3.22

Addictions biology: haplotype-based analysis for 130 candidate genes on a single array. Alcohol Alcohol (2008) 3.13

Allelic and haplotypic association of GABRA2 with alcohol dependence. Am J Med Genet B Neuropsychiatr Genet (2004) 3.10

Diagnostic reliability of the Semi-structured Assessment for Drug Dependence and Alcoholism (SSADDA). Drug Alcohol Depend (2005) 3.09

Association of dopamine agonist use with impulse control disorders in Parkinson disease. Arch Neurol (2006) 3.02

The serotonin transporter genotype and social support and moderation of posttraumatic stress disorder and depression in hurricane-exposed adults. Am J Psychiatry (2007) 2.81

Distress tolerance and early smoking lapse. Clin Psychol Rev (2005) 2.61

Probing compulsive and impulsive behaviors, from animal models to endophenotypes: a narrative review. Neuropsychopharmacology (2009) 2.60

Mindfulness-based treatments for co-occurring depression and substance use disorders: what can we learn from the brain? Addiction (2010) 2.50

Multicenter investigation of the opioid antagonist nalmefene in the treatment of pathological gambling. Am J Psychiatry (2006) 2.50

Strong association of the alcohol dehydrogenase 1B gene (ADH1B) with alcohol dependence and alcohol-induced medical diseases. Biol Psychiatry (2011) 2.45

Interaction of childhood maltreatment with the corticotropin-releasing hormone receptor gene: effects on hypothalamic-pituitary-adrenal axis reactivity. Biol Psychiatry (2009) 2.44

A prospective cohort study investigating factors associated with depression during medical internship. Arch Gen Psychiatry (2010) 2.41

Contemporary behavioral activation treatments for depression: procedures, principles, and progress. Clin Psychol Rev (2003) 2.39

Preliminary validity and reliability testing of a structured clinical interview for pathological gambling. Psychiatry Res (2004) 2.35

DCDC2 is associated with reading disability and modulates neuronal development in the brain. Proc Natl Acad Sci U S A (2005) 2.35

Association between alcoholism and gamma-amino butyric acid alpha2 receptor subtype in a Russian population. Alcohol Clin Exp Res (2005) 2.35

Cue-induced brain activity changes and relapse in cocaine-dependent patients. Neuropsychopharmacology (2006) 2.32

Reliability of DSM-IV diagnostic criteria using the semi-structured assessment for drug dependence and alcoholism (SSADDA). Drug Alcohol Depend (2007) 2.26

The neurobiology and genetics of impulse control disorders: relationships to drug addictions. Biochem Pharmacol (2007) 2.22

Topiramate treatment for heavy drinkers: moderation by a GRIK1 polymorphism. Am J Psychiatry (2014) 2.18

Individuals family history positive for alcoholism show functional magnetic resonance imaging differences in reward sensitivity that are related to impulsivity factors. Biol Psychiatry (2010) 2.16

Interaction of FKBP5 with childhood adversity on risk for post-traumatic stress disorder. Neuropsychopharmacology (2010) 2.16

Broadening our horizon: response to commentaries. Addiction (2012) 2.11

Practical population group assignment with selected informative markers: characteristics and properties of Bayesian clustering via STRUCTURE. Genet Epidemiol (2005) 2.09

Impulse control disorders in adult psychiatric inpatients. Am J Psychiatry (2005) 2.09

Evaluation of behavioral measures of risk taking propensity with inner city adolescents. Behav Res Ther (2005) 2.08

Health correlates of recreational gambling in older adults. Am J Psychiatry (2004) 2.08

Haplotypes at the OPRM1 locus are associated with susceptibility to substance dependence in European-Americans. Am J Med Genet B Neuropsychiatr Genet (2003) 2.07

Pretreatment brain activation during stroop task is associated with outcomes in cocaine-dependent patients. Biol Psychiatry (2008) 2.04

Gender differences in the associations between past-year gambling problems and psychiatric disorders. Soc Psychiatry Psychiatr Epidemiol (2007) 2.02

Interactive effect of stressful life events and the serotonin transporter 5-HTTLPR genotype on posttraumatic stress disorder diagnosis in 2 independent populations. Arch Gen Psychiatry (2009) 1.97

Altered NMDA glutamate receptor antagonist response in individuals with a family vulnerability to alcoholism. Am J Psychiatry (2004) 1.96

Genetic variants of Nogo-66 receptor with possible association to schizophrenia block myelin inhibition of axon growth. J Neurosci (2008) 1.96

Distress tolerance as a predictor of early treatment dropout in a residential substance abuse treatment facility. J Abnorm Psychol (2005) 1.94

Association between two mu-opioid receptor gene (OPRM1) haplotype blocks and drug or alcohol dependence. Hum Mol Genet (2006) 1.93

Investigating the behavioral and self-report constructs of impulsivity domains using principal component analysis. Behav Pharmacol (2009) 1.90

Increased dopamine transporter availability associated with the 9-repeat allele of the SLC6A3 gene. J Nucl Med (2005) 1.89

Validation of the questionnaire for impulsive-compulsive disorders in Parkinson's disease. Mov Disord (2009) 1.89

Anxiety sensitivity: relationship to negative affect smoking and smoking cessation in smokers with past major depressive disorder. Addict Behav (2001) 1.87

An experimental investigation of emotion dysregulation in borderline personality disorder. J Abnorm Psychol (2006) 1.87

A prospective examination of distress tolerance and early smoking lapse in adult self-quitters. Nicotine Tob Res (2009) 1.87

CHRM2 gene predisposes to alcohol dependence, drug dependence and affective disorders: results from an extended case-control structured association study. Hum Mol Genet (2005) 1.85

Diplotype trend regression analysis of the ADH gene cluster and the ALDH2 gene: multiple significant associations with alcohol dependence. Am J Hum Genet (2006) 1.82

Similarities and differences between pathological gambling and substance use disorders: a focus on impulsivity and compulsivity. Psychopharmacology (Berl) (2011) 1.77

Amantadine use associated with impulse control disorders in Parkinson disease in cross-sectional study. Ann Neurol (2010) 1.77

Rare nonsynonymous variants in alpha-4 nicotinic acetylcholine receptor gene protect against nicotine dependence. Biol Psychiatry (2011) 1.76

Problematic Internet use: clinical implications. CNS Spectr (2007) 1.74

Impulse control disorders in Parkinson disease: a multicenter case--control study. Ann Neurol (2011) 1.73

Randomized controlled trial of behavioral activation smoking cessation treatment for smokers with elevated depressive symptoms. J Consult Clin Psychol (2010) 1.73

Gene-by-environment (serotonin transporter and childhood maltreatment) interaction for anxiety sensitivity, an intermediate phenotype for anxiety disorders. Neuropsychopharmacology (2007) 1.71

An FMRI study of the effects of psychostimulants on default-mode processing during Stroop task performance in youths with ADHD. Am J Psychiatry (2009) 1.70

Effects of motivational interviewing on smoking cessation in adolescents with psychiatric disorders. Tob Control (2003) 1.69

Psychiatric correlates of gambling in adolescents and young adults grouped by age at gambling onset. Arch Gen Psychiatry (2004) 1.68

Risk factors in the relationship between gender and crack/cocaine. Exp Clin Psychopharmacol (2007) 1.66

Gamma-aminobutyric acid type A receptors and alcoholism: intoxication, dependence, vulnerability, and treatment. Arch Gen Psychiatry (2006) 1.66

Comorbid psychiatric diagnoses and their association with cocaine-induced psychosis in cocaine-dependent subjects. Am J Addict (2007) 1.63

Variation in GABRA2 predicts drinking behavior in project MATCH subjects. Alcohol Clin Exp Res (2007) 1.62

A common genetic variant in the neurexin superfamily member CNTNAP2 is associated with increased risk for selective mutism and social anxiety-related traits. Biol Psychiatry (2010) 1.62

Mindfulness training and stress reactivity in substance abuse: results from a randomized, controlled stage I pilot study. Subst Abus (2009) 1.62

Impulsive choice and response in dopamine agonist-related impulse control behaviors. Psychopharmacology (Berl) (2009) 1.62

Differences in impulsivity and risk-taking propensity between primary users of crack cocaine and primary users of heroin in a residential substance-use program. Exp Clin Psychopharmacol (2005) 1.61

Genetic and environmental predictors of early alcohol use. Biol Psychiatry (2006) 1.60

Changes in sensation seeking and risk-taking propensity predict increases in alcohol use among early adolescents. Alcohol Clin Exp Res (2010) 1.60

The neurobiology of substance and behavioral addictions. CNS Spectr (2006) 1.59

Modification of the association between serotonin transporter genotype and risk of posttraumatic stress disorder in adults by county-level social environment. Am J Epidemiol (2009) 1.58

ADH4 gene variation is associated with alcohol and drug dependence: results from family controlled and population-structured association studies. Pharmacogenet Genomics (2005) 1.58

Variation in nicotinic acetylcholine receptor genes is associated with multiple substance dependence phenotypes. Neuropsychopharmacology (2010) 1.58

Neurodevelopment, impulsivity, and adolescent gambling. J Gambl Stud (2003) 1.57

Video-gaming among high school students: health correlates, gender differences, and problematic gaming. Pediatrics (2010) 1.56

Association of haplotypic variants in DRD2, ANKK1, TTC12 and NCAM1 to alcohol dependence in independent case control and family samples. Hum Mol Genet (2007) 1.55

Construct validity of the Balloon Analog Risk Task (BART): associations with psychopathy and impulsivity. Assessment (2005) 1.54

Psychological distress tolerance and duration of most recent abstinence attempt among residential treatment-seeking substance abusers. Psychol Addict Behav (2005) 1.52

Nonclinical panic attack history and smoking cessation: an initial examination. Addict Behav (2004) 1.52

Gender differences in adolescent gambling. Ann Clin Psychiatry (2006) 1.51

An initial study of neural responses to monetary incentives as related to treatment outcome in cocaine dependence. Biol Psychiatry (2011) 1.50

Variant callers for next-generation sequencing data: a comparison study. PLoS One (2013) 1.50

Genome-wide association study of alcohol dependence implicates KIAA0040 on chromosome 1q. Neuropsychopharmacology (2011) 1.50

Distress tolerance and early adolescent externalizing and internalizing symptoms: the moderating role of gender and ethnicity. Behav Res Ther (2008) 1.49

A placebo-controlled trial of bupropion combined with nicotine patch for smoking cessation in schizophrenia. Biol Psychiatry (2007) 1.48

Modeling behavior in a clinically diagnostic sequential risk-taking task. Psychol Rev (2005) 1.48

Markers in the 5'-region of GABRG1 associate to alcohol dependence and are in linkage disequilibrium with markers in the adjacent GABRA2 gene. Neuropsychopharmacology (2007) 1.48

Shared brain vulnerabilities open the way for nonsubstance addictions: carving addiction at a new joint? Ann N Y Acad Sci (2010) 1.46

The Gambling Symptom Assessment Scale (G-SAS): a reliability and validity study. Psychiatry Res (2009) 1.46

ADH4 gene variation is associated with alcohol dependence and drug dependence in European Americans: results from HWD tests and case-control association studies. Neuropsychopharmacology (2006) 1.45

Diminished frontostriatal activity during processing of monetary rewards and losses in pathological gambling. Biol Psychiatry (2012) 1.44

Stealing among high school students: prevalence and clinical correlates. J Am Acad Psychiatry Law (2011) 1.43