Published in J Nutr on August 04, 2010
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Luteolin reduces lipopolysaccharide-induced lethal toxicity and expression of proinflammatory molecules in mice. Am J Respir Crit Care Med (2002) 1.18
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Downregulation of IL-4-induced signalling in hippocampus contributes to deficits in LTP in the aged rat. Neurobiol Aging (2005) 1.16
Long-term administration of green tea catechins improves spatial cognition learning ability in rats. J Nutr (2006) 1.13
Regulation of interleukin-6 gene expression in brain of aged mice by nuclear factor kappaB. J Neuroimmunol (2001) 1.12
Inhibition of LPS-stimulated pathways in macrophages by the flavonoid luteolin. Br J Pharmacol (2002) 1.02
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Apigenin and luteolin modulate microglial activation via inhibition of STAT1-induced CD40 expression. J Neuroinflammation (2008) 0.95
Luteolin inhibits the nuclear factor-kappa B transcriptional activity in Rat-1 fibroblasts. Biochem Pharmacol (2003) 0.93
Protective effect of flavonoids against aging- and lipopolysaccharide-induced cognitive impairment in mice. Pharmacology (2003) 0.92
Tripchlorolide protects neuronal cells from microglia-mediated beta-amyloid neurotoxicity through inhibiting NF-kappaB and JNK signaling. Glia (2009) 0.92
Bioavailable flavonoids to suppress the formation of 8-OHdG in HepG2 cells. Arch Biochem Biophys (2006) 0.91
Luteolin protects dopaminergic neurons from inflammation-induced injury through inhibition of microglial activation. Neurosci Lett (2008) 0.88
Determination of St. John's wort flavonoid-metabolites in rat brain through high performance liquid chromatography coupled with fluorescence detection. J Chromatogr B Analyt Technol Biomed Life Sci (2006) 0.88
Suppressive effect of green tea catechins on morphologic and functional regression of the brain in aged mice with accelerated senescence (SAMP10). Exp Gerontol (2004) 0.88
Central infusion of interleukin-1 receptor antagonist blocks the reduction in social behavior produced by prior stressor exposure. Physiol Behav (2009) 0.88
Shifted concentration dependency of EpRE- and XRE-mediated gene expression points at monofunctional EpRE-mediated induction by flavonoids at physiologically relevant concentrations. Toxicol In Vitro (2008) 0.81
From inflammation to sickness and depression: when the immune system subjugates the brain. Nat Rev Neurosci (2008) 15.90
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Cytokine-induced sickness behavior. Brain Behav Immun (2003) 2.70
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Aging exacerbates depressive-like behavior in mice in response to activation of the peripheral innate immune system. Neuropsychopharmacology (2007) 2.20
Aging, microglial cell priming, and the discordant central inflammatory response to signals from the peripheral immune system. J Leukoc Biol (2008) 1.94
Early life iron deficiency impairs spatial cognition in neonatal piglets. J Nutr (2012) 1.87
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Neuroinflammation associated with aging sensitizes the brain to the effects of infection or stress. Neuroimmunomodulation (2008) 1.43
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Luteolin reduces IL-6 production in microglia by inhibiting JNK phosphorylation and activation of AP-1. Proc Natl Acad Sci U S A (2008) 1.42
IL-1beta-mediated innate immunity is amplified in the db/db mouse model of type 2 diabetes. J Immunol (2005) 1.31
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Architectural changes to CA1 pyramidal neurons in adult and aged mice after peripheral immune stimulation. Psychoneuroendocrinology (2008) 1.25
Influenza infection induces neuroinflammation, alters hippocampal neuron morphology, and impairs cognition in adult mice. J Neurosci (2012) 1.25
Age and neuroinflammation: a lifetime of psychoneuroimmune consequences. Neurol Clin (2006) 1.23
Perinatal iron deficiency and neurocognitive development. Front Hum Neurosci (2013) 1.22
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Consuming a diet supplemented with resveratrol reduced infection-related neuroinflammation and deficits in working memory in aged mice. Rejuvenation Res (2009) 1.16
Proinflammatory cytokine impairment of insulin-like growth factor I-induced protein synthesis in skeletal muscle myoblasts requires ceramide. Endocrinology (2004) 1.14
Alpha-tocopherol attenuates lipopolysaccharide-induced sickness behavior in mice. Brain Behav Immun (2004) 1.14
Dysregulated neuronal-microglial cross-talk during aging, stress and inflammation. Exp Neurol (2010) 1.12
Brain growth of the domestic pig (Sus scrofa) from 2 to 24 weeks of age: a longitudinal MRI study. Dev Neurosci (2012) 1.11
alpha-Tocopherol reduces lipopolysaccharide-induced peroxide radical formation and interleukin-6 secretion in primary murine microglia and in brain. J Neuroimmunol (2004) 1.10
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alpha-Tocopherol and selenium facilitate recovery from lipopolysaccharide-induced sickness in aged mice. J Nutr (2005) 0.98
Sickness behavior induced by endotoxin can be mitigated by the dietary soluble fiber, pectin, through up-regulation of IL-4 and Th2 polarization. Brain Behav Immun (2010) 0.97
C-jun N-terminal kinase mediates tumor necrosis factor-alpha suppression of differentiation in myoblasts. Endocrinology (2006) 0.96
Place and direction learning in a spatial T-maze task by neonatal piglets. Anim Cogn (2012) 0.95
Hypoxia/reoxygenation impairs memory formation via adenosine-dependent activation of caspase 1. J Neurosci (2012) 0.91
Regulation of food intake by inflammatory cytokines in the brain. Neuroendocrinology (2007) 0.90
IL-10 promotes survival of microglia without activating Akt. J Neuroimmunol (2002) 0.89
Behavioral assessment of cognitive function using a translational neonatal piglet model. Brain Behav Immun (2010) 0.89
Environmental enrichment attenuates hippocampal neuroinflammation and improves cognitive function during influenza infection. Brain Behav Immun (2012) 0.89
Interleukin-6 trans-signaling in the senescent mouse brain is involved in infection-related deficits in contextual fear conditioning. Brain Behav Immun (2011) 0.88
Magnetic resonance imaging of the neonatal piglet brain. Pediatr Res (2011) 0.88
Cytokine-hormone interactions: tumor necrosis factor alpha impairs biologic activity and downstream activation signals of the insulin-like growth factor I receptor in myoblasts. Endocrinology (2003) 0.86
Central inhibition of interleukin-6 trans-signaling during peripheral infection reduced neuroinflammation and sickness in aged mice. Brain Behav Immun (2013) 0.85
Enhanced neuronal activation in central autonomic network nuclei in aged mice following acute peripheral immune challenge. Auton Neurosci (2006) 0.85
Respiratory viral infection in neonatal piglets causes marked microglia activation in the hippocampus and deficits in spatial learning. J Neurosci (2014) 0.85
The domestic piglet: an important model for investigating the neurodevelopmental consequences of early life insults. Annu Rev Anim Biosci (2014) 0.84
Anti-inflammatory agents inhibit the induction of leptin by tumor necrosis factor-alpha. Am J Physiol Regul Integr Comp Physiol (2002) 0.83
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Insulin-like growth factor-I enhances the biological activity of brain-derived neurotrophic factor on cerebrocortical neurons. J Neuroimmunol (2006) 0.83
IL-1beta suppresses prolonged Akt activation and expression of E2F-1 and cyclin A in breast cancer cells. J Immunol (2004) 0.82
A neurotoxic regimen of methamphetamine exacerbates the febrile and neuroinflammatory response to a subsequent peripheral immune stimulus. J Neuroinflammation (2010) 0.81
Gene expression profiling of 17beta-estradiol and genistein effects on mouse thymus. Toxicol Sci (2005) 0.80
Prototypical anti-inflammatory cytokine IL-10 prevents loss of IGF-I-induced myogenin protein expression caused by IL-1beta. Am J Physiol Endocrinol Metab (2008) 0.80
Heat and social rank impact behavior and physiology of PRRS-virus-infected pigs. Physiol Behav (2006) 0.78
Inhibition of betaine-homocysteine S-methyltransferase in rats causes hyperhomocysteinemia and reduces liver cystathionine β-synthase activity and methylation capacity. Nutr Res (2011) 0.77
Dehydroepiandrosterone-sulfate did not mitigate sickness behavior in mice. Physiol Behav (2004) 0.77
The impact of aging on the brain--risk, resilience and repair. Brain Behav Immun (2012) 0.77
Tumor necrosis factor alpha inhibits insulin-like growth factor I-induced hematopoietic cell survival and proliferation. Endocrinology (2004) 0.77
Prebiotics and Bioactive Milk Fractions Affect Gut Development, Microbiota, and Neurotransmitter Expression in Piglets. J Pediatr Gastroenterol Nutr (2016) 0.76
Decreased protein accretion in pigs with viral and bacterial pneumonia is associated with increased myostatin expression in muscle. J Nutr (2004) 0.76
Dietary L-homoserine spares threonine in chicks. J Nutr (2009) 0.75
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