Published in Mol Cell Biol on August 01, 1991
CpG methylated minichromosomes become inaccessible for V(D)J recombination after undergoing replication. EMBO J (1992) 1.94
Unequal signal and coding joint formation in human V(D)J recombination. Mol Cell Biol (1993) 1.24
Strand specificity in the transcriptional targeting of recombination at immunoglobulin switch sequences. Proc Natl Acad Sci U S A (1995) 1.04
Asymmetric mutation around the recombination break point of immunoglobulin class switch sequences on extrachromosomal substrates. Nucleic Acids Res (1996) 0.82
V(D)J recombination process and the Pre-B to immature B-cells transition are altered in Fanca(-/-) mice. Sci Rep (2016) 0.75
Sequences at the somatic recombination sites of immunoglobulin light-chain genes. Nature (1979) 11.83
An immunoglobulin heavy chain variable region gene is generated from three segments of DNA: VH, D and JH. Cell (1980) 10.35
The V(D)J recombination activating gene, RAG-1. Cell (1989) 9.79
Sequences of five potential recombination sites encoded close to an immunoglobulin kappa constant region gene. Proc Natl Acad Sci U S A (1979) 9.31
Joining of immunoglobulin heavy chain gene segments: implications from a chromosome with evidence of three D-JH fusions. Proc Natl Acad Sci U S A (1982) 8.53
Extrachromosomal DNA substrates in pre-B cells undergo inversion or deletion at immunoglobulin V-(D)-J joining signals. Cell (1987) 4.70
The defect in murine severe combined immune deficiency: joining of signal sequences but not coding segments in V(D)J recombination. Cell (1988) 4.34
V(D)J recombination: a functional definition of the joining signals. Genes Dev (1989) 3.96
Regulation of genome rearrangement events during lymphocyte differentiation. Immunol Rev (1986) 3.65
Developmental stage specificity of the lymphoid V(D)J recombination activity. Genes Dev (1987) 3.65
Homogeneous Escherichia coli endonuclease IV. Characterization of an enzyme that recognizes oxidative damage in DNA. J Biol Chem (1988) 3.15
Increased frequency of N-region insertion in a murine pre-B-cell line infected with a terminal deoxynucleotidyl transferase retroviral expression vector. Mol Cell Biol (1987) 2.33
Role of exonuclease III in the base excision repair of uracil-containing DNA. J Bacteriol (1982) 2.23
DNA elements are asymmetrically joined during the site-specific recombination of kappa immunoglobulin genes. Science (1985) 2.08
Recombined flanks of the variable and joining segments of immunoglobulin genes. Proc Natl Acad Sci U S A (1982) 2.03
Lymphoid V(D)J recombination: nucleotide insertion at signal joints as well as coding joints. Proc Natl Acad Sci U S A (1988) 1.95
A specific DNA sequence controls termination of transcription in the gastrin gene. Mol Cell Biol (1986) 1.88
Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells. Nature (1997) 5.08
Extrachromosomal DNA substrates in pre-B cells undergo inversion or deletion at immunoglobulin V-(D)-J joining signals. Cell (1987) 4.70
Yeast DNA ligase IV mediates non-homologous DNA end joining. Nature (1997) 4.34
V(D)J recombination: a functional definition of the joining signals. Genes Dev (1989) 3.96
The characterization of a mammalian DNA structure-specific endonuclease. EMBO J (1994) 3.85
Restoration of X-ray resistance and V(D)J recombination in mutant cells by Ku cDNA. Science (1994) 3.47
Regulated gene expression in transfected primary chicken erythrocytes. Proc Natl Acad Sci U S A (1986) 3.17
RAG mutations in human B cell-negative SCID. Science (1996) 3.03
DNA ligase IV is essential for V(D)J recombination and DNA double-strand break repair in human precursor lymphocytes. Mol Cell (1998) 2.97
Functional domains within FEN-1 and RAD2 define a family of structure-specific endonucleases: implications for nucleotide excision repair. Genes Dev (1994) 2.87
Lagging strand DNA synthesis at the eukaryotic replication fork involves binding and stimulation of FEN-1 by proliferating cell nuclear antigen. J Biol Chem (1995) 2.80
Interaction of DNA-dependent protein kinase with DNA and with Ku: biochemical and atomic-force microscopy studies. EMBO J (1997) 2.78
V(D)J recombination in mammalian cell mutants defective in DNA double-strand break repair. Mol Cell Biol (1993) 2.66
Electropore diameters, lifetimes, numbers, and locations in individual erythrocyte ghosts. FEBS Lett (1986) 2.32
Retracted Stable RNA/DNA hybrids in the mammalian genome: inducible intermediates in immunoglobulin class switch recombination. Science (2000) 2.17
Processing of branched DNA intermediates by a complex of human FEN-1 and PCNA. Nucleic Acids Res (1996) 2.13
Efficient processing of DNA ends during yeast nonhomologous end joining. Evidence for a DNA polymerase beta (Pol4)-dependent pathway. J Biol Chem (1999) 2.06
CpG methylated minichromosomes become inaccessible for V(D)J recombination after undergoing replication. EMBO J (1992) 1.94
The nonhomologous DNA end joining pathway is important for chromosome stability in primary fibroblasts. Curr Biol (2000) 1.93
RNA:DNA complex formation upon transcription of immunoglobulin switch regions: implications for the mechanism and regulation of class switch recombination. Nucleic Acids Res (1995) 1.93
Mechanistic constraints on diversity in human V(D)J recombination. Mol Cell Biol (1996) 1.86
Requirement for an interaction of XRCC4 with DNA ligase IV for wild-type V(D)J recombination and DNA double-strand break repair in vivo. J Biol Chem (1998) 1.66
Coding end sequence can markedly affect the initiation of V(D)J recombination. Genes Dev (1993) 1.65
A description of the holes in human erythrocyte membrane ghosts. J Biol Chem (1982) 1.60
A role for FEN-1 in nonhomologous DNA end joining: the order of strand annealing and nucleolytic processing events. Proc Natl Acad Sci U S A (1999) 1.59
Productive and nonproductive complexes of Ku and DNA-dependent protein kinase at DNA termini. Mol Cell Biol (1998) 1.51
DNA ligase IV binds to XRCC4 via a motif located between rather than within its BRCT domains. Curr Biol (1998) 1.51
Antigen receptor gene rearrangement. Curr Opin Immunol (1998) 1.48
Retracted Transcription-dependent R-loop formation at mammalian class switch sequences. EMBO J (2000) 1.48
Retraction. Science (2000) 1.42
Extent to which homology can constrain coding exon junctional diversity in V(D)J recombination. Nature (1993) 1.42
DNA structural elements required for FEN-1 binding. J Biol Chem (1995) 1.42
DEAE-dextran enhances electroporation of mammalian cells. Nucleic Acids Res (1992) 1.41
Protein-protein and protein-DNA interaction regions within the DNA end-binding protein Ku70-Ku86. Mol Cell Biol (1996) 1.39
The nicking step in V(D)J recombination is independent of synapsis: implications for the immune repertoire. Mol Cell Biol (2000) 1.38
The RAG-HMG1 complex enforces the 12/23 rule of V(D)J recombination specifically at the double-hairpin formation step. Mol Cell Biol (1998) 1.31
V(D)J recombination in ataxia telangiectasia, Bloom's syndrome, and a DNA ligase I-associated immunodeficiency disorder. J Biol Chem (1993) 1.29
Analysis of the V(D)J recombination efficiency at lymphoid chromosomal translocation breakpoints. J Biol Chem (2001) 1.29
Analysis of the defect in DNA end joining in the murine scid mutation. Mol Cell Biol (1992) 1.28
Transcription, topoisomerases and recombination. Experientia (1994) 1.28
V(D)J recombination: signal and coding joint resolution are uncoupled and depend on parallel synapsis of the sites. Mol Cell Biol (1993) 1.26
Unequal signal and coding joint formation in human V(D)J recombination. Mol Cell Biol (1993) 1.24
V(D)J recombination on minichromosomes is not affected by transcription. J Biol Chem (1992) 1.23
Mechanistic basis for coding end sequence effects in the initiation of V(D)J recombination. Mol Cell Biol (1999) 1.19
Dynamics of the holes in human erythrocyte membrane ghosts. J Biol Chem (1982) 1.16
The basis for the mechanistic bias for deletional over inversional V(D)J recombination. Genes Dev (1992) 1.10
A complex of RAG-1 and RAG-2 proteins persists on DNA after single-strand cleavage at V(D)J recombination signal sequences. Nucleic Acids Res (1997) 1.07
Chimeric molecules created by gene amplification interfere with the analysis of somatic hypermutation of murine immunoglobulin genes. Gene (1994) 1.06
Nm23-H1 mutation in neuroblastoma. Nature (1994) 1.05
Interaction between DNA-dependent protein kinase and a novel protein, KIP. Mutat Res (1997) 1.05
Strand specificity in the transcriptional targeting of recombination at immunoglobulin switch sequences. Proc Natl Acad Sci U S A (1995) 1.04
Human DNA-activated protein kinase (DNA-PK) is homologous to phosphatidylinositol kinases. J Immunol (1995) 1.02
Interaction of chlorpromazine with the human erythrocyte membrane. J Biol Chem (1984) 1.01
Sequence of human FEN-1, a structure-specific endonuclease, and chromosomal localization of the gene (FEN1) in mouse and human. Genomics (1995) 0.98
Is protein turnover thermodynamically controlled? J Biol Chem (1978) 0.95
Studies of V(D)J recombination with extrachromosomal substrates. Curr Top Microbiol Immunol (1988) 0.95
DNA length-dependent cooperative interactions in the binding of Ku to DNA. Biochemistry (2001) 0.93
Malignant thoracopulmonary small-cell ("Askin") tumor. AJR Am J Roentgenol (1985) 0.92
Hemolytic holes in human erythrocyte membrane ghosts. Methods Enzymol (1989) 0.91
Effects of cyclosporine A on biomembranes. Vibrational spectroscopic, calorimetric and hemolysis studies. Biophys J (1986) 0.90
DNA-PK is essential only for coding joint formation in V(D)J recombination. Nucleic Acids Res (1998) 0.88
Analysis of individual immunoglobulin lambda light chain genes amplified from single cells is inconsistent with variable region gene conversion in germinal-center B cell somatic mutation. Eur J Immunol (1994) 0.86
The mammalian FEN-1 locus: structure and conserved sequence features. Microb Comp Genomics (2000) 0.85
A methylated human 9-kb repetitive sequence on acrocentric chromosomes is homologous to a subtelomeric repeat in chimpanzees. Proc Natl Acad Sci U S A (1996) 0.84
Replication, transcription, CpG methylation and DNA topology in V(D)J recombination. Curr Top Microbiol Immunol (1992) 0.84
V(D)J recombination activity in human hematopoietic cells: correlation with developmental stage and genome stability. Eur J Immunol (1998) 0.83
Lymphoid V(D)J recombination. Functional analysis of the spacer sequence within the recombination signal. J Biol Chem (1993) 0.82
Asymmetric mutation around the recombination break point of immunoglobulin class switch sequences on extrachromosomal substrates. Nucleic Acids Res (1996) 0.82
Abnormal V(D)J recombination in murine severe combined immune deficiency: absence of coding joints and formation of alternative products. Abnormal V(D)J recombination in murine severe combined immune deficiency: absence of coding joints and formation of alternative products. Curr Top Microbiol Immunol (1989) 0.81
The role of recombination signal sequences in the preferential joining by deletion in DH-JH recombination and in the ordered rearrangement of the IgH locus. Int Immunol (1997) 0.80
Solid and papillary epithelial neoplasm of the pancreas. An ultrastructural and immunocytochemical study of six cases. Am J Surg Pathol (1987) 0.80
The scid factor on human chromosome 8 restores V(D)J recombination in addition to double-strand break repair. Cancer Res (1995) 0.79
Qualitative and quantitative separation of a series of phorbol-ester tumor promoters by high-pressure liquid chromatography. Cancer Lett (1977) 0.79
Sarcomas arising after radiotherapy for peptic ulcer disease. Dig Dis Sci (1985) 0.79
Transcription targets recombination at immunoglobulin switch sequences in a strand-specific manner. Curr Top Microbiol Immunol (1996) 0.76
Distinct roles for RAG-1 in the initiation of V(D)J recombination and in the resolution of coding ends. J Biol Chem (1994) 0.75
Mechanistic properties of immunoglobulin somatic mutation. Ann N Y Acad Sci (1995) 0.75