Published in Mol Vis on August 22, 2010
Crosstalk between TGF-beta and MAPK signaling during corneal wound healing. Invest Ophthalmol Vis Sci (2011) 0.92
ABCG2-dependent dye exclusion activity and clonal potential in epithelial cells continuously growing for 1 month from limbal explants. Invest Ophthalmol Vis Sci (2011) 0.90
NF-κB feedback control of JNK1 activation modulates TRPV1-induced increases in IL-6 and IL-8 release by human corneal epithelial cells. Mol Vis (2011) 0.87
The role of endogenous epidermal growth factor receptor ligands in mediating corneal epithelial homeostasis. Invest Ophthalmol Vis Sci (2014) 0.83
Gene expression analysis in SV-40 immortalized human corneal epithelial cells cultured with an air-liquid interface. Mol Vis (2010) 0.81
Dependence of corneal epithelial cell proliferation on modulation of interactions between ERK1/2 and NKCC1. Cell Physiol Biochem (2011) 0.79
Exploring the mechanism of WWOX growth inhibitory effects on oral squamous cell carcinoma. Oncol Lett (2017) 0.75
Mammalian MAP kinase signalling cascades. Nature (2001) 18.89
The MAPK signaling cascade. FASEB J (1995) 10.81
Existence of slow-cycling limbal epithelial basal cells that can be preferentially stimulated to proliferate: implications on epithelial stem cells. Cell (1989) 6.49
Dye efflux studies suggest that hematopoietic stem cells expressing low or undetectable levels of CD34 antigen exist in multiple species. Nat Med (1997) 6.13
Regulation of transcription by MAP kinase cascades. Curr Opin Cell Biol (1996) 5.99
Calcium-regulated differentiation of normal human epidermal keratinocytes in chemically defined clonal culture and serum-free serial culture. J Invest Dermatol (1983) 5.05
Dual-specificity phosphatases: critical regulators with diverse cellular targets. Biochem J (2009) 3.98
Nuclear translocation of p42/p44 mitogen-activated protein kinase is required for growth factor-induced gene expression and cell cycle entry. EMBO J (1999) 3.17
Targeting dual-specificity phosphatases: manipulating MAP kinase signalling and immune responses. Nat Rev Drug Discov (2007) 2.97
ERK implication in cell cycle regulation. Biochim Biophys Acta (2006) 2.96
Dual-specificity MAP kinase phosphatases (MKPs) and cancer. Cancer Metastasis Rev (2008) 2.94
The stress-activated protein kinase pathways. Cell Mol Life Sci (1999) 2.72
Thymidine-H3 as a tool for the investigation of the renewal of cell populations. Lab Invest (1959) 2.04
Distinct binding determinants for ERK2/p38alpha and JNK map kinases mediate catalytic activation and substrate selectivity of map kinase phosphatase-1. J Biol Chem (2001) 1.92
Ocular surface epithelia contain ABCG2-dependent side population cells exhibiting features associated with stem cells. J Cell Sci (2005) 1.75
Specific inactivation and nuclear anchoring of extracellular signal-regulated kinase 2 by the inducible dual-specificity protein phosphatase DUSP5. Mol Cell Biol (2005) 1.65
Cross-talk between JNK/SAPK and ERK/MAPK pathways: sustained activation of JNK blocks ERK activation by mitogenic factors. J Biol Chem (2003) 1.49
The subcellular localization of MEK and ERK--a novel nuclear translocation signal (NTS) paves a way to the nucleus. Mol Cell Endocrinol (2009) 1.37
Limbal epithelial side-population cells have stem cell-like properties, including quiescent state. Stem Cells (2005) 1.33
Stress-induced inhibition of ERK1 and ERK2 by direct interaction with p38 MAP kinase. J Biol Chem (2001) 1.23
Stem cells and differentiation stages in the limbo-corneal epithelium. Prog Retin Eye Res (2000) 1.21
Dual specificity phosphatase 1 knockout mice show enhanced susceptibility to anaphylaxis but are sensitive to glucocorticoids. Mol Endocrinol (2007) 1.20
Hyperosmolarity-induced cornification of human corneal epithelial cells is regulated by JNK MAPK. Invest Ophthalmol Vis Sci (2008) 1.12
Comparative analysis of human conjunctival and corneal epithelial gene expression with oligonucleotide microarrays. Invest Ophthalmol Vis Sci (2007) 1.09
IL-1beta induces ER stress in a JNK dependent manner that determines cell death in human pancreatic epithelial MIA PaCa-2 cells. Apoptosis (2010) 1.05
Genomic aberrations and cellular heterogeneity in SV40-immortalized human corneal epithelial cells. Invest Ophthalmol Vis Sci (2008) 1.00
DUSP6/MKP-3 inactivates ERK1/2 but fails to bind and inactivate ERK5. Cell Signal (2007) 0.94
Effluxing ABC transporters in human corneal epithelium. J Pharm Sci (2010) 0.93
Dependence of EGF-induced increases in corneal epithelial proliferation and migration on GSK-3 inactivation. Invest Ophthalmol Vis Sci (2009) 0.90
Molecular profiling of conjunctival epithelial side-population stem cells: atypical cell surface markers and sources of a slow-cycling phenotype. Invest Ophthalmol Vis Sci (2009) 0.88
Differential gene expression in the pig limbal side population: implications for stem cell cycling, replication, and survival. Invest Ophthalmol Vis Sci (2009) 0.86
A metagenome-wide association study of gut microbiota in type 2 diabetes. Nature (2012) 11.68
Cytokine-mediated deployment of SDF-1 induces revascularization through recruitment of CXCR4+ hemangiocytes. Nat Med (2006) 5.22
High frequency of PIK3R1 and PIK3R2 mutations in endometrial cancer elucidates a novel mechanism for regulation of PTEN protein stability. Cancer Discov (2011) 4.78
Chemokine-mediated interaction of hematopoietic progenitors with the bone marrow vascular niche is required for thrombopoiesis. Nat Med (2003) 4.69
A module of negative feedback regulators defines growth factor signaling. Nat Genet (2007) 4.35
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet (2014) 4.13
Effects of glucagon-like peptide-1 on endothelial function in type 2 diabetes patients with stable coronary artery disease. Am J Physiol Endocrinol Metab (2004) 3.65
Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci. Nat Genet (2011) 3.46
BACH1 is critical for homologous recombination and appears to be the Fanconi anemia gene product FANCJ. Cancer Cell (2005) 3.44
Expression of autotaxin and lysophosphatidic acid receptors increases mammary tumorigenesis, invasion, and metastases. Cancer Cell (2009) 3.36
Hemifusion in SNARE-mediated membrane fusion. Nat Struct Mol Biol (2005) 3.33
A Technical Assessment of the Utility of Reverse Phase Protein Arrays for the Study of the Functional Proteome in Non-microdissected Human Breast Cancers. Clin Proteomics (2010) 3.25
The Drosophila HP1 homolog Rhino is required for transposon silencing and piRNA production by dual-strand clusters. Cell (2009) 3.13
Generation of functional multipotent adult stem cells from GPR125+ germline progenitors. Nature (2007) 3.01
Gcn5 promotes acetylation, eviction, and methylation of nucleosomes in transcribed coding regions. Mol Cell (2007) 2.71
Multiple intermediates in SNARE-induced membrane fusion. Proc Natl Acad Sci U S A (2006) 2.65
Structural variation in two human genomes mapped at single-nucleotide resolution by whole genome de novo assembly. Nat Biotechnol (2011) 2.45
The BRCA1-associated protein BACH1 is a DNA helicase targeted by clinically relevant inactivating mutations. Proc Natl Acad Sci U S A (2004) 2.41
Oncogenic PIK3CA-driven mammary tumors frequently recur via PI3K pathway-dependent and PI3K pathway-independent mechanisms. Nat Med (2011) 2.34
Hepatic sinusoidal obstruction syndrome associated with consumption of Gynura segetum. J Hepatol (2010) 2.33
Whole-exome sequencing combined with functional genomics reveals novel candidate driver cancer genes in endometrial cancer. Genome Res (2012) 2.27
MicroRNA-206 colocalizes with ribosome-rich regions in both the nucleolus and cytoplasm of rat myogenic cells. Proc Natl Acad Sci U S A (2006) 2.15
The Chromosome-Centric Human Proteome Project for cataloging proteins encoded in the genome. Nat Biotechnol (2012) 2.14
Domains of eIF1A that mediate binding to eIF2, eIF3 and eIF5B and promote ternary complex recruitment in vivo. EMBO J (2003) 2.12
Interactions of eukaryotic translation initiation factor 3 (eIF3) subunit NIP1/c with eIF1 and eIF5 promote preinitiation complex assembly and regulate start codon selection. Mol Cell Biol (2004) 2.09
Chaperone-mediated pathway of proteasome regulatory particle assembly. Nature (2009) 2.07
Down-regulation of caspase 3 in breast cancer: a possible mechanism for chemoresistance. Oncogene (2002) 2.03
NAD synthase NMNAT acts as a chaperone to protect against neurodegeneration. Nature (2008) 2.01
The bHLH genes GLABRA3 (GL3) and ENHANCER OF GLABRA3 (EGL3) specify epidermal cell fate in the Arabidopsis root. Development (2003) 1.86
Alterations of the hSNF5/INI1 gene in central nervous system atypical teratoid/rhabdoid tumors and renal and extrarenal rhabdoid tumors. Clin Cancer Res (2002) 1.81
Alternative promoters regulate transcription of the gene that encodes stem cell surface protein AC133. Blood (2003) 1.78
Ocular surface epithelia contain ABCG2-dependent side population cells exhibiting features associated with stem cells. J Cell Sci (2005) 1.75
Differential roles of CB1 and CB2 cannabinoid receptors in mast cells. J Immunol (2003) 1.75
Tie2 activation contributes to hemangiogenic regeneration after myelosuppression. Blood (2005) 1.73
The RABIT: a rapid automated biodosimetry tool for radiological triage. Health Phys (2010) 1.69
Generation of a functional and durable vascular niche by the adenoviral E4ORF1 gene. Proc Natl Acad Sci U S A (2008) 1.69
Combretastatin A4 phosphate induces rapid regression of tumor neovessels and growth through interference with vascular endothelial-cadherin signaling. J Clin Invest (2005) 1.68
VEGF-B inhibits apoptosis via VEGFR-1-mediated suppression of the expression of BH3-only protein genes in mice and rats. J Clin Invest (2008) 1.68
Endothelium-derived microparticles impair endothelial function in vitro. Am J Physiol Heart Circ Physiol (2004) 1.68
Laboratory surge response to pandemic (H1N1) 2009 outbreak, New York City metropolitan area, USA. Emerg Infect Dis (2010) 1.67
P-TEFb is not an essential elongation factor for the intronless human U2 snRNA and histone H2b genes. EMBO J (2005) 1.66
Continuous locomotion-mode identification for prosthetic legs based on neuromuscular-mechanical fusion. IEEE Trans Biomed Eng (2011) 1.65
Pharmacokinetic role of L-type amino acid transporters LAT1 and LAT2. Eur J Pharm Sci (2008) 1.62
Structure of a RSC-nucleosome complex and insights into chromatin remodeling. Nat Struct Mol Biol (2008) 1.62
Protein kinase C delta mediates arterial injury responses through regulation of vascular smooth muscle cell apoptosis. Cardiovasc Res (2009) 1.59
Intrarenal transfer of an intracellular fluorescent fusion of angiotensin II selectively in proximal tubules increases blood pressure in rats and mice. Am J Physiol Renal Physiol (2011) 1.59
Membrane fusion induced by neuronal SNAREs transits through hemifusion. J Biol Chem (2005) 1.56
The E3 ligase HACE1 is a critical chromosome 6q21 tumor suppressor involved in multiple cancers. Nat Med (2007) 1.55
Different cell sizes in human limbal and central corneal basal epithelia measured by confocal microscopy and flow cytometry. Invest Ophthalmol Vis Sci (2003) 1.53
Shedding of HIV and human herpesviruses in the semen of effectively treated HIV-1-infected men who have sex with men. Clin Infect Dis (2013) 1.53
Bis[5-(2-pyrid-yl)pyrazine-2-carbonitrile]-silver(I) tetra-fluorido-borate. Acta Crystallogr Sect E Struct Rep Online (2010) 1.51
Determination of acetolactate synthase activity and protein content of oilseed rape (Brassica napus L.) leaves using visible/near-infrared spectroscopy. Anal Chim Acta (2008) 1.51
Akt/Protein kinase B is required for lymphatic network formation, remodeling, and valve development. Am J Pathol (2010) 1.51
Distribution and characterization of over 1000 T-DNA tags in rice genome. Plant J (2003) 1.50
Semaphorin 3E initiates antiangiogenic signaling through plexin D1 by regulating Arf6 and R-Ras. Mol Cell Biol (2010) 1.50
Interdependent recruitment of SAGA and Srb mediator by transcriptional activator Gcn4p. Mol Cell Biol (2005) 1.47
Both flow-mediated vasodilation procedures and acute exercise improve endothelial function in obese young men. Eur J Appl Physiol (2010) 1.47
Gold nanoparticles enable selective light-induced contents release from liposomes. J Control Release (2007) 1.46
Drug transport in corneal epithelium and blood-retina barrier: emerging role of transporters in ocular pharmacokinetics. Adv Drug Deliv Rev (2006) 1.46
SubpathwayMiner: a software package for flexible identification of pathways. Nucleic Acids Res (2009) 1.45
Prevention and reversal of premature endothelial cell senescence and vasculopathy in obesity-induced diabetes by ebselen. Circ Res (2003) 1.44
Improved seedless hydrothermal synthesis of dense and ultralong ZnO nanowires. Nanotechnology (2011) 1.43
Applying linear and non-linear methods for parallel prediction of volume of distribution and fraction of unbound drug. PLoS One (2013) 1.43
Prognostic role of serum carbohydrate antigen 19-9 levels in patients with resectable hepatocellular carcinoma. Tumour Biol (2015) 1.42
Mitochondrial DNA evidence for a diversified origin of workers building First Emperor of China. PLoS One (2008) 1.40
Design and fabrication of an artificial cornea based on a photolithographically patterned hydrogel construct. Biomed Microdevices (2007) 1.38
Functional proteomic analysis of advanced serous ovarian cancer using reverse phase protein array: TGF-beta pathway signaling indicates response to primary chemotherapy. Clin Cancer Res (2010) 1.38
miR-126 inhibits non-small cell lung cancer cells proliferation by targeting EGFL7. Biochem Biophys Res Commun (2009) 1.38
Porous 3D graphene-based bulk materials with exceptional high surface area and excellent conductivity for supercapacitors. Sci Rep (2013) 1.36
Thrombospondins deployed by thrombopoietic cells determine angiogenic switch and extent of revascularization. J Clin Invest (2006) 1.35
Invasive mechanism and management strategy of Bemisia tabaci (Gennadius) biotype B: progress report of 973 Program on invasive alien species in China. Sci China C Life Sci (2009) 1.35
Current and future ophthalmic drug delivery systems. A shift to the posterior segment. Drug Discov Today (2008) 1.33
Survival effect of PDGF-CC rescues neurons from apoptosis in both brain and retina by regulating GSK3beta phosphorylation. J Exp Med (2010) 1.33
The tight junction protein, occludin, regulates the directional migration of epithelial cells. Dev Cell (2010) 1.32
Epithelial-mesenchymal transition (EMT) induced by TNF-α requires AKT/GSK-3β-mediated stabilization of snail in colorectal cancer. PLoS One (2013) 1.31
The C-terminal region of eukaryotic translation initiation factor 3a (eIF3a) promotes mRNA recruitment, scanning, and, together with eIF3j and the eIF3b RNA recognition motif, selection of AUG start codons. Mol Cell Biol (2010) 1.31
Methylenetetrahydrofolate reductase polymorphisms and breast cancer risk: a meta-analysis from 41 studies with 16,480 cases and 22,388 controls. Breast Cancer Res Treat (2010) 1.31
An essential role for the RNA-binding protein Smaug during the Drosophila maternal-to-zygotic transition. Development (2009) 1.31
Phosphatase-mediated crosstalk control of ERK and p38 MAPK signaling in corneal epithelial cells. Invest Ophthalmol Vis Sci (2006) 1.29
Bright and color-saturated emission from blue light-emitting diodes based on solution-processed colloidal nanocrystal quantum dots. Nano Lett (2007) 1.27
Real-time video imaging of protease expression in vivo. Theranostics (2011) 1.27
A TRPV2-PKA signaling module for transduction of physical stimuli in mast cells. J Exp Med (2004) 1.25
Rice breeding in the post-genomics era: from concept to practice. Curr Opin Plant Biol (2013) 1.25
Chimeric ferritin nanocages for multiple function loading and multimodal imaging. Nano Lett (2011) 1.24
A role for monoubiquitinated FANCD2 at telomeres in ALT cells. Nucleic Acids Res (2009) 1.24
Permeability of retinal pigment epithelium: effects of permeant molecular weight and lipophilicity. Invest Ophthalmol Vis Sci (2005) 1.24
Systematic analysis of genotype-specific drug responses in cancer. Int J Cancer (2012) 1.23
A pathway for the control of anoikis sensitivity by E-cadherin and epithelial-to-mesenchymal transition. Mol Cell Biol (2011) 1.23
HPD: an online integrated human pathway database enabling systems biology studies. BMC Bioinformatics (2009) 1.21
MRG15 binds directly to PALB2 and stimulates homology-directed repair of chromosomal breaks. J Cell Sci (2010) 1.20
Estimates of the number of prevalent and incident human immunodeficiency virus (HIV) infections in Canada, 2008. Can J Public Health (2011) 1.20
Depletion of eIF4G from yeast cells narrows the range of translational efficiencies genome-wide. BMC Genomics (2011) 1.19
Complete genome sequence of the metabolically versatile halophilic archaeon Haloferax mediterranei, a poly(3-hydroxybutyrate-co-3-hydroxyvalerate) producer. J Bacteriol (2012) 1.19
Ferroportin1 deficiency in mouse macrophages impairs iron homeostasis and inflammatory responses. Blood (2011) 1.18
Autocrine/paracrine pattern of superoxide production through NAD(P)H oxidase in coronary arterial myocytes. Am J Physiol Heart Circ Physiol (2006) 1.17
Data integration gets 'Sloppy'. Nat Biotechnol (2006) 1.17
Effects of echo time on diffusion quantification of brain white matter at 1.5 T and 3.0 T. Magn Reson Med (2009) 1.17
Lysosomal targeting and trafficking of acid sphingomyelinase to lipid raft platforms in coronary endothelial cells. Arterioscler Thromb Vasc Biol (2008) 1.16
Association of ADIPOQ gene polymorphisms and coronary artery disease risk: a meta-analysis based on 12 465 subjects. Thromb Res (2012) 1.16