Published in Brain Res on August 31, 2010
Induced tauopathy in a novel 3D-culture model mediates neurodegenerative processes: a real-time study on biochips. PLoS One (2012) 1.43
Is protein phosphatase inhibition responsible for the toxic effects of okadaic Acid in animals? Toxins (Basel) (2013) 0.85
Recent development of multifunctional agents as potential drug candidates for the treatment of Alzheimer's disease. Curr Med Chem (2015) 0.81
Targeting Hsp90 and its co-chaperones to treat Alzheimer's disease. Expert Opin Ther Targets (2014) 0.81
Tau Hyperphosphorylation and Oxidative Stress, a Critical Vicious Circle in Neurodegenerative Tauopathies? Oxid Med Cell Longev (2015) 0.80
Can zebrafish be used as animal model to study Alzheimer's disease? Am J Neurodegener Dis (2012) 0.80
Quercetin Protects against Okadaic Acid-Induced Injury via MAPK and PI3K/Akt/GSK3β Signaling Pathways in HT22 Hippocampal Neurons. PLoS One (2016) 0.78
A systems biology investigation of neurodegenerative dementia reveals a pivotal role of autophagy. BMC Syst Biol (2014) 0.77
Toxin-Induced Experimental Models of Learning and Memory Impairment. Int J Mol Sci (2016) 0.76
A local insult of okadaic acid in wild-type mice induces tau phosphorylation and protein aggregation in anatomically distinct brain regions. Acta Neuropathol Commun (2016) 0.76
Oral toxicity of okadaic acid in mice: study of lethality, organ damage, distribution and effects on detoxifying gene expression. Toxins (Basel) (2013) 0.76
Use of okadaic acid to identify relevant phosphoepitopes in pathology: a focus on neurodegeneration. Mar Drugs (2013) 0.75
Original Research: Influence of okadaic acid on hyperphosphorylation of tau and nicotinic acetylcholine receptors in primary neurons. Exp Biol Med (Maywood) (2016) 0.75
A roadmap for the prevention of dementia II: Leon Thal Symposium 2008. Alzheimers Dement (2009) 10.21
Depletion of GGA3 stabilizes BACE and enhances beta-secretase activity. Neuron (2007) 3.98
Mitochondrial localization of estrogen receptor beta. Proc Natl Acad Sci U S A (2004) 2.15
Acarbose, 17-α-estradiol, and nordihydroguaiaretic acid extend mouse lifespan preferentially in males. Aging Cell (2013) 1.71
Increased beta-secretase activity and expression in rats following transient cerebral ischemia. Brain Res (2004) 1.59
Alternative mitochondrial electron transfer as a novel strategy for neuroprotection. J Biol Chem (2011) 1.41
Quinol-based cyclic antioxidant mechanism in estrogen neuroprotection. Proc Natl Acad Sci U S A (2003) 1.37
Testosterone increases neurotoxicity of glutamate in vitro and ischemia-reperfusion injury in an animal model. J Appl Physiol (1985) (2002) 1.35
Estrogen attenuates nuclear factor-kappa B activation induced by transient cerebral ischemia. Brain Res (2004) 1.29
Estrogens and progesterone as neuroprotectants: what animal models teach us. Front Biosci (2008) 1.25
Estrogens directly potentiate neuronal L-type Ca2+ channels. Proc Natl Acad Sci U S A (2008) 1.22
Cdk5 is involved in NFT-like tauopathy induced by transient cerebral ischemia in female rats. Biochim Biophys Acta (2006) 1.20
17beta-Estradiol attenuates blood-brain barrier disruption induced by cerebral ischemia-reperfusion injury in female rats. Brain Res (2005) 1.18
Neuroprotective effects of an estratriene analog are estrogen receptor independent in vitro and in vivo. Brain Res (2005) 1.16
Oxidative damage to human lens epithelial cells in culture: estrogen protection of mitochondrial potential, ATP, and cell viability. Invest Ophthalmol Vis Sci (2003) 1.15
Novel mechanisms for estrogen-induced neuroprotection. Exp Biol Med (Maywood) (2006) 1.09
Structure-nongenomic neuroprotection relationship of estrogens and estrogen-derived compounds. Pharmacol Ther (2007) 1.09
Role of PPAR-gamma ligands in neuroprotection against glutamate-induced cytotoxicity in retinal ganglion cells. Invest Ophthalmol Vis Sci (2003) 1.09
Transient cerebral ischemia induces site-specific hyperphosphorylation of tau protein. Brain Res (2004) 1.08
Transient cerebral ischemia induces aberrant neuronal cell cycle re-entry and Alzheimer's disease-like tauopathy in female rats. J Biol Chem (2004) 1.07
Neuroprotective effects of 17beta-estradiol and nonfeminizing estrogens against H2O2 toxicity in human neuroblastoma SK-N-SH cells. Mol Pharmacol (2006) 1.06
Estrogen protects the inner retina from apoptosis and ischemia-induced loss of Vesl-1L/Homer 1c immunoreactive synaptic connections. Invest Ophthalmol Vis Sci (2003) 1.05
Reversing the Warburg effect as a treatment for glioblastoma. J Biol Chem (2013) 1.02
Combination therapy of 17beta-estradiol and recombinant tissue plasminogen activator for experimental ischemic stroke. J Pharmacol Exp Ther (2009) 1.02
Estrogen receptor beta as a mitochondrial vulnerability factor. J Biol Chem (2009) 1.02
Mechanistic investigations on the antioxidant action of a neuroprotective estrogen derivative. Steroids (2007) 1.02
Rapid mitochondrial dysfunction mediates TNF-alpha-induced neurotoxicity. J Neurochem (2015) 1.01
Neuroprotective effects of a novel non-receptor-binding estrogen analogue: in vitro and in vivo analysis. Stroke (2002) 1.01
A prototypical Sigma-1 receptor antagonist protects against brain ischemia. Brain Res (2007) 0.99
Neuroprotective actions of methylene blue and its derivatives. PLoS One (2012) 0.99
Subcellular distribution of native estrogen receptor alpha and beta subtypes in cultured human lens epithelial cells. Exp Eye Res (2004) 0.97
Dose dependence and therapeutic window for the neuroprotective effects of 17beta-estradiol when administered after cerebral ischemia. Neurosci Lett (2007) 0.96
Glutamate receptor activation evokes calpain-mediated degradation of Sp3 and Sp4, the prominent Sp-family transcription factors in neurons. J Neurochem (2007) 0.96
Role of protein phosphatases in estrogen-mediated neuroprotection. J Neurosci (2005) 0.95
The use of estrogens and related compounds in the treatment of damage from cerebral ischemia. Ann N Y Acad Sci (2003) 0.95
The effect of atrazine administered by gavage or in diet on the LH surge and reproductive performance in intact female Sprague-Dawley and Long Evans rats. Birth Defects Res B Dev Reprod Toxicol (2014) 0.93
Estrogen protection in Friedreich's ataxia skin fibroblasts. Endocrinology (2011) 0.92
Neuroprotective effects of PPARgamma agonists against oxidative insults in HT-22 cells. Eur J Pharmacol (2003) 0.91
Neuroendocrine mechanism for tolerance to cerebral ischemia-reperfusion injury in male rats. J Neurobiol (2005) 0.91
Estrogens as protectants of the neurovascular unit against ischemic stroke. Curr Drug Targets CNS Neurol Disord (2005) 0.91
Estrogen receptor-independent neuroprotection via protein phosphatase preservation and attenuation of persistent extracellular signal-regulated kinase 1/2 activation. J Pharmacol Exp Ther (2007) 0.89
Proestrus levels of estradiol during transient global cerebral ischemia improves the histological outcome of the hippocampal CA1 region: perfusion-dependent and-independent mechanisms. J Neurol Sci (2002) 0.89
Cell-cycle regulators are involved in transient cerebral ischemia induced neuronal apoptosis in female rats. FEBS Lett (2005) 0.88
Estradiol protects against cerebellar damage and motor deficit in ethanol-withdrawn rats. Alcohol (2002) 0.88
Ethanol withdrawal posttranslationally decreases the activity of cytochrome c oxidase in an estrogen reversible manner. Neurosci Lett (2007) 0.88
Okadaic acid induces tau phosphorylation in SH-SY5Y cells in an estrogen-preventable manner. Brain Res (2010) 0.87
Estrogen treatment following severe burn injury reduces brain inflammation and apoptotic signaling. J Neuroinflammation (2009) 0.87
The assessment of non-feminizing estrogens for use in neuroprotection. Brain Res (2010) 0.87
Estrone is neuroprotective in rats after traumatic brain injury. J Neurotrauma (2012) 0.87
Transient focal cerebral ischemia induces long-term cognitive function deficit in an experimental ischemic stroke model. Neurobiol Dis (2013) 0.86
Estrogen protects against brain lipid peroxidation in ethanol-withdrawn rats. Pharmacol Biochem Behav (2004) 0.86
Estrogen prevents oxidative damage to the mitochondria in Friedreich's ataxia skin fibroblasts. PLoS One (2012) 0.85
Ethanol withdrawal acts as an age-specific stressor to activate cerebellar p38 kinase. Neurobiol Aging (2010) 0.85
Role of nonfeminizing estrogen analogues in neuroprotection of rat retinal ganglion cells against glutamate-induced cytotoxicity. Free Radic Biol Med (2005) 0.85
Protein phosphatase 1, protein phosphatase 2A, and calcineurin play a role in estrogen-mediated neuroprotection. Endocrinology (2008) 0.84
Noninvasive monitoring of estrogen effects against ischemic stroke in rats by near-infrared spectroscopy. Appl Opt (2007) 0.84
Modulation of polymorphonuclear neutrophil functions by astrocytes. J Neuroinflammation (2010) 0.84
Divergent mechanisms for trophic actions of estrogens in the brain and peripheral tissues. Brain Res (2010) 0.84
Mechanism of okadaic acid-induced neuronal death and the effect of estrogens. J Neurochem (2008) 0.83
Neuroprotective effects of high affinity Σ1 receptor selective compounds. Brain Res (2011) 0.83
17beta-Estradiol extends ischemic thresholds and exerts neuroprotective effects in cerebral subcortex against transient focal cerebral ischemia in rats. Brain Res (2003) 0.83
An N-heterocyclic amine chelate capable of antioxidant capacity and amyloid disaggregation. ACS Chem Neurosci (2012) 0.82
Therapeutic strategies in Friedreich's ataxia. Brain Res (2013) 0.82
Quinol-based metabolic cycle for estrogens in rat liver microsomes. Drug Metab Dispos (2003) 0.82
nNOS is involved in estrogen mediated neuroprotection in neuroblastoma cells. Neuroreport (2004) 0.82
Role of the GABA-A system in estrogen-induced protection against brain lipid peroxidation in ethanol-withdrawn rats. Alcohol Clin Exp Res (2004) 0.81
Hippocampal progenitor cells express nestin following cerebral ischemia in rats. Neuroreport (2005) 0.81
Neuroprotective effects of nonfeminizing estrogens in retinal photoreceptor neurons. Invest Ophthalmol Vis Sci (2012) 0.81
Ethanol withdrawal hastens the aging of cytochrome c oxidase. Neurobiol Aging (2011) 0.81
Pyruvate enhances neurological recovery following cardiopulmonary arrest and resuscitation. Resuscitation (2007) 0.81
Involvement of estrogen receptor β5 in the progression of glioma. Brain Res (2013) 0.81
Role of the GABAA system in behavioral, motoric, and cerebellar protection by estrogen during ethanol withdrawal. Alcohol (2003) 0.81
Intermittent hypoxia conditioning prevents behavioral deficit and brain oxidative stress in ethanol-withdrawn rats. J Appl Physiol (1985) (2008) 0.81
Correspondence regarding Schwend and Gustafsson, "False positives in MALDI-TOF detection of ERbeta in mitochondria". Biochem Biophys Res Commun (2006) 0.80
A nonfeminizing estrogen analog protects against ethanol withdrawal toxicity in immortalized hippocampal cells. J Pharmacol Exp Ther (2006) 0.80
A potent antioxidant small molecule aimed at targeting metal-based oxidative stress in neurodegenerative disorders. Chem Commun (Camb) (2013) 0.80
Ethanol withdrawal provokes mitochondrial injury in an estrogen preventable manner. J Bioenerg Biomembr (2008) 0.80
Role of parvalbumin in estrogen protection from ethanol withdrawal syndrome. Alcohol Clin Exp Res (2005) 0.80
Role of protein kinase C in estrogen protection against apoptotic cerebellar cell death in ethanol-withdrawn rats. Alcohol (2003) 0.80
Ethanol withdrawal provokes opening of the mitochondrial membrane permeability transition pore in an estrogen-preventable manner. J Pharmacol Exp Ther (2008) 0.79
Increased severity of acute cerebral ischemic injury correlates with enhanced stem cell induction as well as with predictive behavioral profiling. Curr Neurovasc Res (2004) 0.79
Simultaneous quantification of four native estrogen hormones at trace levels in human cerebrospinal fluid using liquid chromatography-tandem mass spectrometry. J Pharm Biomed Anal (2010) 0.79
Phenolic compounds protect cultured hippocampal neurons against ethanol-withdrawal induced oxidative stress. Int J Mol Sci (2009) 0.78
Consortium for the Assessment of Research on Progestins and Estrogens (CARPE) Fort Worth, Texas August 1-3, 2003. J Womens Health (Larchmt) (2004) 0.78
Window of opportunity for estrogen and progestin intervention in brain aging and Alzheimer's disease. Brain Res (2013) 0.78
Estrogen-induced signaling attenuates soluble Aβ peptide-mediated dysfunction of pathways in synaptic plasticity. Brain Res (2011) 0.77
Alkaloids from the hook-bearing branch of Uncariarhynchophylla and their neuroprotective effects against glutamate-induced HT22 cell death. J Asian Nat Prod Res (2014) 0.77
Amyloid-β peptide fibrils induce nitro-oxidative stress in neuronal cells. J Alzheimers Dis (2010) 0.77
Retracted Estrogens and neuroprotection in retinal diseases. Mol Vis (2008) 0.77
Suppression of protein kinase Cepsilon mediates 17beta-estradiol-induced neuroprotection in an immortalized hippocampal cell line. J Neurochem (2005) 0.76
R- and S-equol have equivalent cytoprotective effects in Friedreich's ataxia. BMC Pharmacol Toxicol (2012) 0.76
Retention behavior of estrogen metabolites on hydrophilic interaction chromatography stationary phases. J Sep Sci (2010) 0.75
Menopausal Vasomotor Symptoms (MVS) survey for assessment of hot flashes. J Womens Health (Larchmt) (2006) 0.75
Ethanol withdrawal reduces cerebellar parvalbumin expression in a manner reversed by estrogens. Neurosci Lett (2004) 0.75
Potential testosterone therapy for hypogonadal sexual dysfunction in women. J Womens Health (Larchmt) (2005) 0.75
A Paper-based Surface-Enhanced Raman Scattering Lateral Flow Strip for Detection of Neuron-Specific Enolase in Blood Plasma. Anal Chem (2017) 0.75
Investigation of the temperature stability of premarin intravenous using liquid chromatography-mass spectrometry. J Pharm Biomed Anal (2011) 0.75