Signaling complexes of voltage-gated sodium and calcium channels.

PubWeight™: 1.34‹?› | Rank: Top 10%

🔗 View Article (PMC 3433163)

Published in Neurosci Lett on September 17, 2010

Authors

William A Catterall1

Author Affiliations

1: Department of Pharmacology, Box 357280, University of Washington, Seattle, WA 98195-7280, United States. wcatt@u.washington.edu

Articles citing this

The Na(V)1.7 sodium channel: from molecule to man. Nat Rev Neurosci (2012) 2.71

Somatic and germline CACNA1D calcium channel mutations in aldosterone-producing adenomas and primary aldosteronism. Nat Genet (2013) 2.09

Cell permeabilization and inhibition of voltage-gated Ca(2+) and Na(+) channel currents by nanosecond pulsed electric field. Bioelectromagnetics (2011) 1.54

Fluorescent saxitoxins for live cell imaging of single voltage-gated sodium ion channels beyond the optical diffraction limit. Chem Biol (2012) 1.50

Inhibition of voltage-gated Na(+) current by nanosecond pulsed electric field (nsPEF) is not mediated by Na(+) influx or Ca(2+) signaling. Bioelectromagnetics (2012) 1.46

The sigma-1 receptor: roles in neuronal plasticity and disease. Trends Neurosci (2012) 1.22

The Sick and the Weak: Neuropathies/Myopathies in the Critically Ill. Physiol Rev (2015) 1.20

Presynaptic CaV1.3 channels regulate synaptic ribbon size and are required for synaptic maintenance in sensory hair cells. J Neurosci (2012) 1.17

A voltage-gated sodium channel is essential for the positive selection of CD4(+) T cells. Nat Immunol (2012) 1.15

Noncanonical Hedgehog signaling. Vitam Horm (2012) 1.14

Differential regulation of CaV1.2 channels by cAMP-dependent protein kinase bound to A-kinase anchoring proteins 15 and 79/150. J Gen Physiol (2014) 1.08

Flufenamic acid as an ion channel modulator. Pharmacol Ther (2013) 0.94

Molecular Heterogeneity in Aldosterone-Producing Adenomas. J Clin Endocrinol Metab (2016) 0.94

Weft, warp, and weave: the intricate tapestry of calcium channels regulating T lymphocyte function. Front Immunol (2013) 0.93

Channelopathies from mutations in the cardiac sodium channel protein complex. J Mol Cell Cardiol (2013) 0.93

Bioluminescence methodology for the detection of protein-protein interactions within the voltage-gated sodium channel macromolecular complex. Assay Drug Dev Technol (2012) 0.92

NALCN ion channels have alternative selectivity filters resembling calcium channels or sodium channels. PLoS One (2013) 0.88

The role of auxiliary subunits for the functional diversity of voltage-gated calcium channels. J Cell Physiol (2015) 0.87

Control of neuronal ion channel function by glycogen synthase kinase-3: new prospective for an old kinase. Front Mol Neurosci (2012) 0.86

Manipulating L-type calcium channels in cardiomyocytes using split-intein protein transsplicing. Proc Natl Acad Sci U S A (2013) 0.85

Challenging the catechism of therapeutics for chronic neuropathic pain: Targeting CaV2.2 interactions with CRMP2 peptides. Neurosci Lett (2013) 0.82

Small-conductance Ca2+ -activated K+ channels and cardiac arrhythmias. Heart Rhythm (2015) 0.81

Structure-function of proteins interacting with the α1 pore-forming subunit of high-voltage-activated calcium channels. Front Physiol (2014) 0.81

Cardiac ion channels. Channels (Austin) (2015) 0.80

Structure of potassium channels. Cell Mol Life Sci (2015) 0.79

Regulation of Cardiac Calcium Channels in the Fight-or-Flight Response. Curr Mol Pharmacol (2015) 0.79

Quantitative proteomics reveals protein-protein interactions with fibroblast growth factor 12 as a component of the voltage-gated sodium channel 1.2 (nav1.2) macromolecular complex in Mammalian brain. Mol Cell Proteomics (2015) 0.79

Transsynaptic channelosomes: non-conducting roles of ion channels in synapse formation. Channels (Austin) (2011) 0.77

Molecular mechanism of Spinocerebellar Ataxia type 6: glutamine repeat disorder, channelopathy and transcriptional dysregulation. The multifaceted aspects of a single mutation. Front Cell Neurosci (2015) 0.77

A voltage-gated sodium channel mediates positive selection of T cells. Nat Immunol (2012) 0.76

Surface dynamics of voltage-gated ion channels. Channels (Austin) (2016) 0.76

Finding Channels. J Biol Chem (2015) 0.76

Leucine-Rich Repeat Kinase 2 (Lrrk2)-Sensitive Na(+)/K(+) ATPase Activity in Dendritic Cells. Sci Rep (2017) 0.75

The Auxiliary Calcium Channel Subunit α2δ4 Is Required for Axonal Elaboration, Synaptic Transmission, and Wiring of Rod Photoreceptors. Neuron (2017) 0.75

Contribution of protein kinase Cα in the stimulation of insulin by the down-regulation of Cavβ subunits. Endocrine (2014) 0.75

Variation in sodium current amplitude between vasopressin and oxytocin hypothalamic supraoptic neurons. J Neurophysiol (2012) 0.75

Biallelic SCN10A mutations in neuromuscular disease and epileptic encephalopathy. Ann Clin Transl Neurol (2016) 0.75

Basis for a neuronal version of Grover's quantum algorithm. Front Mol Neurosci (2014) 0.75

Articles cited by this

(truncated to the top 100)

A quantitative description of membrane current and its application to conduction and excitation in nerve. J Physiol (1952) 160.83

Structure and regulation of voltage-gated Ca2+ channels. Annu Rev Cell Dev Biol (2000) 9.88

Signaling through scaffold, anchoring, and adaptor proteins. Science (1997) 9.48

The synaptic vesicle cycle: a cascade of protein-protein interactions. Nature (1995) 7.48

Calcium channel modulation by neurotransmitters, enzymes and drugs. Nature (1983) 6.76

Regulation and modulation of calcium channels in cardiac, skeletal, and smooth muscle cells. Physiol Rev (1994) 5.51

Enhanced dihydropyridine receptor channel activity in the presence of ryanodine receptor. Nature (1996) 4.42

AnkyrinG is required for clustering of voltage-gated Na channels at axon initial segments and for normal action potential firing. J Cell Biol (1998) 4.41

Preassociation of calmodulin with voltage-gated Ca(2+) channels revealed by FRET in single living cells. Neuron (2001) 4.28

Neurotransmitter inhibition of neuronal calcium currents by changes in channel voltage dependence. Nature (1989) 4.19

Voltage-dependent modulation of N-type calcium channels by G-protein beta gamma subunits. Nature (1996) 4.01

Modulation of ion-channel function by G-protein-coupled receptors. Trends Neurosci (1994) 3.80

Modulation of Ca2+ channels by G-protein beta gamma subunits. Nature (1996) 3.79

The regulation of the calcium conductance of cardiac muscle by adrenaline. J Physiol (1977) 3.33

Mechanisms of calcium channel modulation by beta-adrenergic agents and dihydropyridine calcium agonists. J Mol Cell Cardiol (1986) 3.31

Calcium channel regulation and presynaptic plasticity. Neuron (2008) 3.28

Ca2+/calmodulin binds to and modulates P/Q-type calcium channels. Nature (1999) 3.24

cAMP-dependent regulation of cardiac L-type Ca2+ channels requires membrane targeting of PKA and phosphorylation of channel subunits. Neuron (1997) 3.21

Calmodulin bifurcates the local Ca2+ signal that modulates P/Q-type Ca2+ channels. Nature (2001) 2.95

Direct binding of G-protein betagamma complex to voltage-dependent calcium channels. Nature (1997) 2.60

Sodium channel beta4, a new disulfide-linked auxiliary subunit with similarity to beta2. J Neurosci (2003) 2.58

Inactivation of presynaptic calcium current contributes to synaptic depression at a fast central synapse. Neuron (1998) 2.56

Crosstalk between G proteins and protein kinase C mediated by the calcium channel alpha1 subunit. Nature (1997) 2.55

Functional impact of syntaxin on gating of N-type and Q-type calcium channels. Nature (1995) 2.46

Purification of the calcium antagonist receptor of the voltage-sensitive calcium channel from skeletal muscle transverse tubules. Biochemistry (1984) 2.36

Injection of subunits of cyclic AMP-dependent protein kinase into cardiac myocytes modulates Ca2+ current. Nature (1982) 2.33

Regulation of presynaptic Ca(V)2.1 channels by Ca2+ sensor proteins mediates short-term synaptic plasticity. Neuron (2008) 2.30

Neuromodulation of Na+ channels: an unexpected form of cellular plasticity. Nat Rev Neurosci (2001) 2.28

A sodium channel signaling complex: modulation by associated receptor protein tyrosine phosphatase beta. Nat Neurosci (2000) 2.25

Molecular mechanism of calcium channel regulation in the fight-or-flight response. Sci Signal (2010) 2.25

Sodium channel beta subunits mediate homophilic cell adhesion and recruit ankyrin to points of cell-cell contact. J Biol Chem (2000) 2.24

Specific phosphorylation of a site in the full-length form of the alpha 1 subunit of the cardiac L-type calcium channel by adenosine 3',5'-cyclic monophosphate-dependent protein kinase. Biochemistry (1996) 2.24

Subunit structure of dihydropyridine-sensitive calcium channels from skeletal muscle. Proc Natl Acad Sci U S A (1987) 2.22

Acute changes in short-term plasticity at synapses with elevated levels of neuronal calcium sensor-1. Nat Neurosci (2003) 2.18

Beta-adrenergic regulation requires direct anchoring of PKA to cardiac CaV1.2 channels via a leucine zipper interaction with A kinase-anchoring protein 15. Proc Natl Acad Sci U S A (2003) 2.09

Identification of a syntaxin-binding site on N-type calcium channels. Neuron (1994) 2.09

Voltage-dependent potentiation of L-type Ca2+ channels due to phosphorylation by cAMP-dependent protein kinase. Nature (1993) 2.06

A novel lipid-anchored A-kinase Anchoring Protein facilitates cAMP-responsive membrane events. EMBO J (1998) 2.05

Calcium-dependent interaction of N-type calcium channels with the synaptic core complex. Nature (1996) 2.03

Effects of dopamine and noradrenaline on Ca channels of cultured sensory and sympathetic neurons of chick. Pflugers Arch (1986) 2.02

Inhibition of neurotransmission by peptides containing the synaptic protein interaction site of N-type Ca2+ channels. Neuron (1996) 1.98

Direct interaction of gbetagamma with a C-terminal gbetagamma-binding domain of the Ca2+ channel alpha1 subunit is responsible for channel inhibition by G protein-coupled receptors. Proc Natl Acad Sci U S A (1997) 1.96

Autoinhibitory control of the CaV1.2 channel by its proteolytically processed distal C-terminal domain. J Physiol (2006) 1.92

Differential modulation of Ca(v)2.1 channels by calmodulin and Ca2+-binding protein 1. Nat Neurosci (2002) 1.86

Quantitative proteomics of the Cav2 channel nano-environments in the mammalian brain. Proc Natl Acad Sci U S A (2010) 1.85

Modification of Ca2+ channel activity by deletions at the carboxyl terminus of the cardiac alpha 1 subunit. J Biol Chem (1994) 1.85

Ca2+/calmodulin-dependent facilitation and inactivation of P/Q-type Ca2+ channels. J Neurosci (2000) 1.81

A novel mechanism of PKA anchoring revealed by solution structures of anchoring complexes. EMBO J (2001) 1.75

Functional interaction of syntaxin and SNAP-25 with voltage-sensitive L- and N-type Ca2+ channels. EMBO J (1996) 1.75

Neuronal calcium sensor 1 and activity-dependent facilitation of P/Q-type calcium currents at presynaptic nerve terminals. Science (2002) 1.75

Subunits of purified calcium channels: a 212-kDa form of alpha 1 and partial amino acid sequence of a phosphorylation site of an independent beta subunit. Proc Natl Acad Sci U S A (1989) 1.74

Characterization of the two size forms of the alpha 1 subunit of skeletal muscle L-type calcium channels. Proc Natl Acad Sci U S A (1991) 1.70

Sites of proteolytic processing and noncovalent association of the distal C-terminal domain of CaV1.1 channels in skeletal muscle. Proc Natl Acad Sci U S A (2005) 1.68

Phosphorylation of the calcium antagonist receptor of the voltage-sensitive calcium channel by cAMP-dependent protein kinase. Proc Natl Acad Sci U S A (1985) 1.67

A kinase anchor proteins and the intracellular targeting of signals carried by cyclic AMP. Biochim Biophys Acta (1994) 1.65

Convergent regulation of sodium channels by protein kinase C and cAMP-dependent protein kinase. Science (1993) 1.64

Facilitation of the presynaptic calcium current at an auditory synapse in rat brainstem. J Physiol (1998) 1.61

Molecular determinants of inactivation and G protein modulation in the intracellular loop connecting domains I and II of the calcium channel alpha1A subunit. Proc Natl Acad Sci U S A (1997) 1.61

Sodium channel beta1 and beta3 subunits associate with neurofascin through their extracellular immunoglobulin-like domain. J Cell Biol (2001) 1.60

C-terminal fragments of the alpha 1C (CaV1.2) subunit associate with and regulate L-type calcium channels containing C-terminal-truncated alpha 1C subunits. J Biol Chem (2001) 1.59

A novel leucine zipper targets AKAP15 and cyclic AMP-dependent protein kinase to the C terminus of the skeletal muscle Ca2+ channel and modulates its function. J Biol Chem (2001) 1.57

Isoform-specific interaction of the alpha1A subunits of brain Ca2+ channels with the presynaptic proteins syntaxin and SNAP-25. Proc Natl Acad Sci U S A (1996) 1.56

Voltage-dependent modulation of N-type calcium channels: role of G protein subunits. Adv Second Messenger Phosphoprotein Res (1999) 1.54

Adrenaline-like effects of intracellular iontophoresis of cyclic AMP in cardiac Purkinje fibres. Nat New Biol (1973) 1.54

Differential phosphorylation of two size forms of the neuronal class C L-type calcium channel alpha 1 subunit. J Biol Chem (1993) 1.53

Molecular determinants of Ca(2+)/calmodulin-dependent regulation of Ca(v)2.1 channels. Proc Natl Acad Sci U S A (2003) 1.52

Multiple structural elements in voltage-dependent Ca2+ channels support their inhibition by G proteins. Neuron (1996) 1.51

Transmitter modulation of slow, activity-dependent alterations in sodium channel availability endows neurons with a novel form of cellular plasticity. Neuron (2003) 1.51

Primary structure and function of an A kinase anchoring protein associated with calcium channels. Neuron (1998) 1.51

Reciprocal regulation of P/Q-type Ca2+ channels by SNAP-25, syntaxin and synaptotagmin. Nat Neurosci (1999) 1.49

Facilitation of presynaptic calcium currents in the rat brainstem. J Physiol (1998) 1.49

Functional modulation of brain sodium channels by cAMP-dependent phosphorylation. Neuron (1992) 1.48

Voltage-dependent potentiation of L-type Ca2+ channels in skeletal muscle cells requires anchored cAMP-dependent protein kinase. Proc Natl Acad Sci U S A (1994) 1.48

Voltage-gated Na+ channel beta1 subunit-mediated neurite outgrowth requires Fyn kinase and contributes to postnatal CNS development in vivo. J Neurosci (2008) 1.41

Proteolytic processing of the C terminus of the alpha(1C) subunit of L-type calcium channels and the role of a proline-rich domain in membrane tethering of proteolytic fragments. J Biol Chem (2000) 1.41

Localization of A-kinase through anchoring proteins. Mol Endocrinol (1994) 1.41

Identification of a 15-kDa cAMP-dependent protein kinase-anchoring protein associated with skeletal muscle L-type calcium channels. J Biol Chem (1997) 1.38

Neuromodulation of Na+ channel slow inactivation via cAMP-dependent protein kinase and protein kinase C. Neuron (2006) 1.38

The biochemistry of neurotransmitter secretion. J Biol Chem (1995) 1.37

Alteration of Ca2+ dependence of neurotransmitter release by disruption of Ca2+ channel/syntaxin interaction. J Neurosci (1997) 1.35

Functional reciprocity between Na+ channel Nav1.6 and beta1 subunits in the coordinated regulation of excitability and neurite outgrowth. Proc Natl Acad Sci U S A (2010) 1.34

Modulation of CaV2.1 channels by Ca2+/calmodulin-dependent protein kinase II bound to the C-terminal domain. Proc Natl Acad Sci U S A (2007) 1.33

Phosphorylation at a single site in the rat brain sodium channel is necessary and sufficient for current reduction by protein kinase A. J Neurosci (1997) 1.30

Modulation of CaV2.1 channels by the neuronal calcium-binding protein visinin-like protein-2. J Neurosci (2005) 1.30

Identification of residues in the N terminus of alpha1B critical for inhibition of the voltage-dependent calcium channel by Gbeta gamma. J Neurosci (1999) 1.29

Contactin associates with Na+ channels and increases their functional expression. J Neurosci (2001) 1.27

P/Q-type calcium channels mediate the activity-dependent feedback of syntaxin-1A. Nature (1999) 1.26

Interaction of voltage-gated sodium channels with the extracellular matrix molecules tenascin-C and tenascin-R. Proc Natl Acad Sci U S A (1998) 1.26

Tenascin-R is a functional modulator of sodium channel beta subunits. J Biol Chem (1999) 1.25

Cyclic AMP-dependent phosphorylation of the alpha subunit of the sodium channel in synaptic nerve ending particles. J Biol Chem (1984) 1.24

Modulation of the cloned skeletal muscle L-type Ca2+ channel by anchored cAMP-dependent protein kinase. J Neurosci (1997) 1.23

Modulation of Ca2+ channels by protein kinase C in rat central and peripheral neurons: disruption of G protein-mediated inhibition. Neuron (1993) 1.23

Dopaminergic modulation of sodium current in hippocampal neurons via cAMP-dependent phosphorylation of specific sites in the sodium channel alpha subunit. J Neurosci (1997) 1.22

Differential modulation of sodium channel gating and persistent sodium currents by the beta1, beta2, and beta3 subunits. Mol Cell Neurosci (2001) 1.21

Interaction of the synprint site of N-type Ca2+ channels with the C2B domain of synaptotagmin I. Proc Natl Acad Sci U S A (1997) 1.20

Purification of a functional receptor for calcium-channel blockers from rabbit skeletal-muscle microsomes. Eur J Biochem (1986) 1.20

Protein kinase C modulates glutamate receptor inhibition of Ca2+ channels and synaptic transmission. Nature (1993) 1.20

Selective phosphorylation of the alpha subunit of the sodium channel by cAMP-dependent protein kinase. J Biol Chem (1982) 1.20

The intracellular loop between domains I and II of the B-type calcium channel confers aspects of G-protein sensitivity to the E-type calcium channel. J Neurosci (1997) 1.17

Phosphorylation of the synaptic protein interaction site on N-type calcium channels inhibits interactions with SNARE proteins. J Neurosci (1997) 1.15