PubRank

Michael R Maurizi

Author PubWeight™ 29.02‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Crystal structure of ClpA, an Hsp100 chaperone and regulator of ClpAP protease. J Biol Chem 2002 1.97
2 Acyldepsipeptide antibiotics induce the formation of a structured axial channel in ClpP: A model for the ClpX/ClpA-bound state of ClpP. Chem Biol 2010 1.48
3 The catalytic domain of Escherichia coli Lon protease has a unique fold and a Ser-Lys dyad in the active site. J Biol Chem 2003 1.33
4 Crystallography and mutagenesis point to an essential role for the N-terminus of human mitochondrial ClpP. J Struct Biol 2004 1.27
5 Functional proteolytic complexes of the human mitochondrial ATP-dependent protease, hClpXP. J Biol Chem 2002 1.24
6 Turnover of mitochondrial steroidogenic acute regulatory (StAR) protein by Lon protease: the unexpected effect of proteasome inhibitors. Mol Endocrinol 2007 1.20
7 Crystal structure at 1.9A of E. coli ClpP with a peptide covalently bound at the active site. J Struct Biol 2006 1.17
8 Crystal structure of the heterodimeric complex of the adaptor, ClpS, with the N-domain of the AAA+ chaperone, ClpA. J Biol Chem 2002 1.15
9 Alternating translocation of protein substrates from both ends of ClpXP protease. EMBO J 2002 1.14
10 The N-terminal substrate-binding domain of ClpA unfoldase is highly mobile and extends axially from the distal surface of ClpAP protease. J Struct Biol 2004 1.13
11 ClpA and ClpX ATPases bind simultaneously to opposite ends of ClpP peptidase to form active hybrid complexes. J Struct Biol 2004 1.10
12 Turnover of endogenous SsrA-tagged proteins mediated by ATP-dependent proteases in Escherichia coli. J Biol Chem 2008 1.08
13 Crystallographic investigation of peptide binding sites in the N-domain of the ClpA chaperone. J Struct Biol 2004 1.05
14 Human mitochondrial ClpP is a stable heptamer that assembles into a tetradecamer in the presence of ClpX. J Biol Chem 2005 1.04
15 Slicing a protease: structural features of the ATP-dependent Lon proteases gleaned from investigations of isolated domains. Protein Sci 2006 1.03
16 Crystal structure of Lon protease: molecular architecture of gated entry to a sequestered degradation chamber. EMBO J 2010 1.00
17 Crystal structure of the N-terminal domain of E. coli Lon protease. Protein Sci 2005 0.99
18 Crystal structure of the AAA+ alpha domain of E. coli Lon protease at 1.9A resolution. J Struct Biol 2004 0.99
19 Local and global mobility in the ClpA AAA+ chaperone detected by cryo-electron microscopy: functional connotations. Structure 2010 0.97
20 Binding of the ClpA unfoldase opens the axial gate of ClpP peptidase. J Biol Chem 2010 0.94
21 A single ClpS monomer is sufficient to direct the activity of the ClpA hexamer. J Biol Chem 2010 0.92
22 4-O-carboxymethyl ascochlorin causes ER stress and induced autophagy in human hepatocellular carcinoma cells. J Biol Chem 2012 0.90
23 The molecular chaperone, ClpA, has a single high affinity peptide binding site per hexamer. J Biol Chem 2005 0.90
24 Love it or cleave it: tough choices in protein quality control. Nat Struct Biol 2002 0.86
25 Structure of the N-terminal fragment of Escherichia coli Lon protease. Acta Crystallogr D Biol Crystallogr 2010 0.83
26 The N-degradome of Escherichia coli: limited proteolysis in vivo generates a large pool of proteins bearing N-degrons. J Biol Chem 2013 0.83
27 The purification of the Chlamydomonas reinhardtii chloroplast ClpP complex: additional subunits and structural features. Plant Mol Biol 2012 0.83