Published in J Struct Biol on March 23, 2004
A novel ATP-dependent conformation in p97 N-D1 fragment revealed by crystal structures of disease-related mutants. EMBO J (2010) 1.85
Visualizing the ATPase cycle in a protein disaggregating machine: structural basis for substrate binding by ClpB. Mol Cell (2007) 1.82
Interpretation of electron density with stereographic roadmap projections. J Struct Biol (2006) 1.64
Atypical AAA+ subunit packing creates an expanded cavity for disaggregation by the protein-remodeling factor Hsp104. Cell (2007) 1.56
CryoEM structure of Hsp104 and its mechanistic implication for protein disaggregation. Proc Natl Acad Sci U S A (2010) 1.49
The molecular basis of N-end rule recognition. Mol Cell (2008) 1.36
Motor mechanism for protein threading through Hsp104. Mol Cell (2009) 1.33
Cryo-EM structure of dodecameric Vps4p and its 2:1 complex with Vta1p. J Mol Biol (2008) 1.33
Synchrotron protein footprinting supports substrate translocation by ClpA via ATP-induced movements of the D2 loop. Structure (2008) 1.05
One number does not fit all: mapping local variations in resolution in cryo-EM reconstructions. J Struct Biol (2013) 1.03
Local and global mobility in the ClpA AAA+ chaperone detected by cryo-electron microscopy: functional connotations. Structure (2010) 0.97
A single ClpS monomer is sufficient to direct the activity of the ClpA hexamer. J Biol Chem (2010) 0.92
MuB is an AAA+ ATPase that forms helical filaments to control target selection for DNA transposition. Proc Natl Acad Sci U S A (2013) 0.87
Architecture and molecular mechanism of PAN, the archaeal proteasome regulatory ATPase. J Biol Chem (2009) 0.86
Mechanistic and Structural Insights into the Prion-Disaggregase Activity of Hsp104. J Mol Biol (2015) 0.85
Subdomain organization of the Acanthamoeba myosin IC tail from cryo-electron microscopy. Proc Natl Acad Sci U S A (2004) 0.84
Structural and motional contributions of the Bacillus subtilis ClpC N-domain to adaptor protein interactions. J Mol Biol (2009) 0.82
Role of a conserved pore residue in the formation of a prehydrolytic high substrate affinity state in the AAA+ chaperone ClpA. Biochemistry (2008) 0.82
Structural basis for the disaggregase activity and regulation of Hsp104. Elife (2016) 0.82
The Sm-like Hfq protein increases OxyS RNA interaction with target mRNAs. Mol Cell (2002) 5.69
Outcome of the first electron microscopy validation task force meeting. Structure (2012) 4.35
Three-dimensional structure of herpes simplex virus from cryo-electron tomography. Science (2003) 3.82
Influenza virus pleiomorphy characterized by cryoelectron tomography. Proc Natl Acad Sci U S A (2006) 3.25
Dynamics of herpes simplex virus capsid maturation visualized by time-lapse cryo-electron microscopy. Nat Struct Biol (2003) 2.78
Structural and functional similarities between the capsid proteins of bacteriophages T4 and HK97 point to a common ancestry. Proc Natl Acad Sci U S A (2005) 2.53
Arrangement of L2 within the papillomavirus capsid. J Virol (2008) 2.37
Structural engineering of a phage lysin that targets gram-negative pathogens. Proc Natl Acad Sci U S A (2012) 2.36
Structure and polymorphism of the UL6 portal protein of herpes simplex virus type 1. J Virol (2004) 2.35
Functional architecture of the retromer cargo-recognition complex. Nature (2007) 2.26
The structure of the poliovirus 135S cell entry intermediate at 10-angstrom resolution reveals the location of an externalized polypeptide that binds to membranes. J Virol (2005) 2.20
Crystal structure of ClpA, an Hsp100 chaperone and regulator of ClpAP protease. J Biol Chem (2002) 1.97
Allosteric signaling and a nuclear exit strategy: binding of UL25/UL17 heterodimers to DNA-Filled HSV-1 capsids. Mol Cell (2007) 1.96
Computational resources for cryo-electron tomography in Bsoft. J Struct Biol (2007) 1.87
A resolution criterion for electron tomography based on cross-validation. J Struct Biol (2005) 1.85
Visualization of a missing link in retrovirus capsid assembly. Nature (2009) 1.75
Characterization of beta-sheet structure in Ure2p1-89 yeast prion fibrils by solid-state nuclear magnetic resonance. Biochemistry (2007) 1.73
Membrane curvature induction and tubulation are common features of synucleins and apolipoproteins. J Biol Chem (2010) 1.69
Architecture of Ure2p prion filaments: the N-terminal domains form a central core fiber. J Biol Chem (2003) 1.66
High-resolution mass spectrometry of viral assemblies: molecular composition and stability of dimorphic hepatitis B virus capsids. Proc Natl Acad Sci U S A (2008) 1.64
Visualization of the herpes simplex virus portal in situ by cryo-electron tomography. Virology (2006) 1.63
A model for Ure2p prion filaments and other amyloids: the parallel superpleated beta-structure. Proc Natl Acad Sci U S A (2004) 1.62
Mechanism of inactivation on prion conversion of the Saccharomyces cerevisiae Ure2 protein. Proc Natl Acad Sci U S A (2002) 1.61
A novel class of herpesvirus with bivalve hosts. J Gen Virol (2005) 1.60
The parallel superpleated beta-structure as a model for amyloid fibrils of human amylin. J Mol Biol (2005) 1.56
Implications of the HIV-1 Rev dimer structure at 3.2 A resolution for multimeric binding to the Rev response element. Proc Natl Acad Sci U S A (2010) 1.51
Structural basis for iron piracy by pathogenic Neisseria. Nature (2012) 1.50
Acyldepsipeptide antibiotics induce the formation of a structured axial channel in ClpP: A model for the ClpX/ClpA-bound state of ClpP. Chem Biol (2010) 1.48
Beta-rolls, beta-helices, and other beta-solenoid proteins. Adv Protein Chem (2006) 1.37
Beta arcades: recurring motifs in naturally occurring and disease-related amyloid fibrils. FASEB J (2009) 1.37
Mass analysis by scanning transmission electron microscopy and electron diffraction validate predictions of stacked beta-solenoid model of HET-s prion fibrils. J Biol Chem (2006) 1.36
HIV-1 maturation inhibitor bevirimat stabilizes the immature Gag lattice. J Virol (2010) 1.33
The catalytic domain of Escherichia coli Lon protease has a unique fold and a Ser-Lys dyad in the active site. J Biol Chem (2003) 1.33
Maturation of flaviviruses starts from one or more icosahedrally independent nucleation centres. EMBO Rep (2011) 1.31
Structural changes in Influenza virus at low pH characterized by cryo-electron tomography. J Virol (2012) 1.30
Prospects of electron cryotomography to visualize macromolecular complexes inside cellular compartments: implications of crowding. Biophys Chem (2003) 1.30
The morphogenic linker peptide of HBV capsid protein forms a mobile array on the interior surface. EMBO J (2002) 1.29
mtCLIC/CLIC4, an organellular chloride channel protein, is increased by DNA damage and participates in the apoptotic response to p53. Mol Cell Biol (2002) 1.28
Crystallography and mutagenesis point to an essential role for the N-terminus of human mitochondrial ClpP. J Struct Biol (2004) 1.27
An externalized polypeptide partitions between two distinct sites on genome-released poliovirus particles. J Virol (2011) 1.26
Electron microscopic evidence in support of alpha-solenoid models of proteasomal subunits Rpn1 and Rpn2. J Mol Biol (2009) 1.25
Control of crosslinking by quaternary structure changes during bacteriophage HK97 maturation. Mol Cell (2004) 1.25
Functional proteolytic complexes of the human mitochondrial ATP-dependent protease, hClpXP. J Biol Chem (2002) 1.24
Human immunodeficiency virus type 1 N-terminal capsid mutants containing cores with abnormally high levels of capsid protein and virtually no reverse transcriptase. J Virol (2003) 1.24
Time-resolved molecular dynamics of bacteriophage HK97 capsid maturation interpreted by electron cryo-microscopy and X-ray crystallography. J Struct Biol (2005) 1.24
New HEAT-like repeat motifs in proteins regulating proteasome structure and function. J Struct Biol (2004) 1.23
The axial channel of the 20S proteasome opens upon binding of the PA200 activator. J Mol Biol (2005) 1.22
Handedness of the herpes simplex virus capsid and procapsid. J Virol (2002) 1.21
Stability and shape of hepatitis B virus capsids in vacuo. Angew Chem Int Ed Engl (2008) 1.20
Crosslinking renders bacteriophage HK97 capsid maturation irreversible and effects an essential stabilization. EMBO J (2005) 1.20
A thermally induced phase transition in a viral capsid transforms the hexamers, leaving the pentamers unchanged. J Struct Biol (2006) 1.20
A free energy cascade with locks drives assembly and maturation of bacteriophage HK97 capsid. J Mol Biol (2006) 1.20
Turnover of mitochondrial steroidogenic acute regulatory (StAR) protein by Lon protease: the unexpected effect of proteasome inhibitors. Mol Endocrinol (2007) 1.20
RSV capsid polymorphism correlates with polymerization efficiency and envelope glycoprotein content: implications that nucleation controls morphogenesis. J Mol Biol (2007) 1.19
A second symmetry mismatch at the portal vertex of bacteriophage T7: 8-fold symmetry in the procapsid core. J Mol Biol (2003) 1.18
The turn of the screw: variations of the abundant beta-solenoid motif in passenger domains of Type V secretory proteins. J Struct Biol (2006) 1.18
Crystal structure at 1.9A of E. coli ClpP with a peptide covalently bound at the active site. J Struct Biol (2006) 1.17
Molecular mechanisms in bacteriophage T7 procapsid assembly, maturation, and DNA containment. Adv Protein Chem (2003) 1.16
Crystal structure of the heterodimeric complex of the adaptor, ClpS, with the N-domain of the AAA+ chaperone, ClpA. J Biol Chem (2002) 1.15
Recombinant HA1 produced in E. coli forms functional oligomers and generates strain-specific SRID potency antibodies for pandemic influenza vaccines. Vaccine (2011) 1.14
Alternating translocation of protein substrates from both ends of ClpXP protease. EMBO J (2002) 1.14
Initial stages of V(D)J recombination: the organization of RAG1/2 and RSS DNA in the postcleavage complex. Mol Cell (2009) 1.13
The role of capsid maturation on adenovirus priming for sequential uncoating. J Biol Chem (2012) 1.13
Irregular and Semi-Regular Polyhedral Models for Rous Sarcoma Virus Cores. Comput Math Methods Med (2008) 1.12
Procapsid assembly, maturation, nuclear exit: dynamic steps in the production of infectious herpesvirions. Adv Exp Med Biol (2012) 1.12
Prion and non-prion amyloids of the HET-s prion forming domain. J Mol Biol (2007) 1.11
Is the prion domain of soluble Ure2p unstructured? Biochemistry (2005) 1.11
ClpA and ClpX ATPases bind simultaneously to opposite ends of ClpP peptidase to form active hybrid complexes. J Struct Biol (2004) 1.10
Filaments of the Ure2p prion protein have a cross-beta core structure. J Struct Biol (2005) 1.09
Multiple modes of endophilin-mediated conversion of lipid vesicles into coated tubes: implications for synaptic endocytosis. J Biol Chem (2010) 1.09
Structure, function, and amyloidogenesis of fungal prions: filament polymorphism and prion variants. Adv Protein Chem (2006) 1.09
Standard conformations of beta-arches in beta-solenoid proteins. J Mol Biol (2006) 1.08
Turnover of endogenous SsrA-tagged proteins mediated by ATP-dependent proteases in Escherichia coli. J Biol Chem (2008) 1.08
Initial location of the RNA-dependent RNA polymerase in the bacteriophage Phi6 procapsid determined by cryo-electron microscopy. J Biol Chem (2008) 1.08
Remodeling of lipid vesicles into cylindrical micelles by α-synuclein in an extended α-helical conformation. J Biol Chem (2012) 1.07
Assembly and architecture of biogenesis of lysosome-related organelles complex-1 (BLOC-1). J Biol Chem (2011) 1.07
Crystallographic investigation of peptide binding sites in the N-domain of the ClpA chaperone. J Struct Biol (2004) 1.05
Control of virus assembly: HK97 "Whiffleball" mutant capsids without pentons. J Mol Biol (2005) 1.04
Human mitochondrial ClpP is a stable heptamer that assembles into a tetradecamer in the presence of ClpX. J Biol Chem (2005) 1.04
One number does not fit all: mapping local variations in resolution in cryo-EM reconstructions. J Struct Biol (2013) 1.03
Slicing a protease: structural features of the ATP-dependent Lon proteases gleaned from investigations of isolated domains. Protein Sci (2006) 1.03
A two-pronged structural analysis of retroviral maturation indicates that core formation proceeds by a disassembly-reassembly pathway rather than a displacive transition. J Virol (2013) 1.02
Structure and assembly of a paramyxovirus matrix protein. Proc Natl Acad Sci U S A (2012) 1.01
Structural and enzymatic properties of the AAA protein Drg1p from Saccharomyces cerevisiae. Decoupling of intracellular function from ATPase activity and hexamerization. J Biol Chem (2002) 1.00
Crystal structure of Lon protease: molecular architecture of gated entry to a sequestered degradation chamber. EMBO J (2010) 1.00
Generation and characterization of a chimeric rabbit/human Fab for co-crystallization of HIV-1 Rev. J Mol Biol (2010) 1.00
Virus capsid expansion driven by the capture of mobile surface loops. Structure (2008) 0.99
Crystal structure of the N-terminal domain of E. coli Lon protease. Protein Sci (2005) 0.99
Structural dependence of HET-s amyloid fibril infectivity assessed by cryoelectron microscopy. Proc Natl Acad Sci U S A (2011) 0.99
Crystal structure of the AAA+ alpha domain of E. coli Lon protease at 1.9A resolution. J Struct Biol (2004) 0.99
Structure and energetics of encapsidated DNA in bacteriophage HK97 studied by scanning calorimetry and cryo-electron microscopy. J Mol Biol (2009) 0.99
Amyloid structure and assembly: insights from scanning transmission electron microscopy. J Struct Biol (2010) 0.98
At low pH, influenza virus matrix protein M1 undergoes a conformational change prior to dissociating from the membrane. J Virol (2013) 0.98
Poliovirus 2C protein forms homo-oligomeric structures required for ATPase activity. J Biol Chem (2009) 0.97
The UL36 tegument protein of herpes simplex virus 1 has a composite binding site at the capsid vertices. J Virol (2012) 0.97
Local and global mobility in the ClpA AAA+ chaperone detected by cryo-electron microscopy: functional connotations. Structure (2010) 0.97