1
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Resistance exercise increases AMPK activity and reduces 4E-BP1 phosphorylation and protein synthesis in human skeletal muscle.
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J Physiol
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2006
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3.08
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2
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Rapamycin administration in humans blocks the contraction-induced increase in skeletal muscle protein synthesis.
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J Physiol
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2009
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2.64
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3
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Leucine-enriched essential amino acid and carbohydrate ingestion following resistance exercise enhances mTOR signaling and protein synthesis in human muscle.
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Am J Physiol Endocrinol Metab
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2007
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2.26
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4
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Dietary protein recommendations and the prevention of sarcopenia.
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Curr Opin Clin Nutr Metab Care
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2009
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2.26
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5
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Nutrient signalling in the regulation of human muscle protein synthesis.
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J Physiol
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2007
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2.22
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6
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Skeletal muscle protein anabolic response to resistance exercise and essential amino acids is delayed with aging.
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J Appl Physiol (1985)
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2008
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2.20
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7
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Blood flow restriction during low-intensity resistance exercise increases S6K1 phosphorylation and muscle protein synthesis.
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J Appl Physiol (1985)
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2007
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1.79
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8
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Aging impairs contraction-induced human skeletal muscle mTORC1 signaling and protein synthesis.
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2011
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1.68
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9
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Nutritional and contractile regulation of human skeletal muscle protein synthesis and mTORC1 signaling.
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J Appl Physiol (1985)
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2009
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1.65
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10
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Mammalian target of rapamycin complex 1 activation is required for the stimulation of human skeletal muscle protein synthesis by essential amino acids.
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J Nutr
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2011
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1.60
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11
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Excess leucine intake enhances muscle anabolic signaling but not net protein anabolism in young men and women.
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J Nutr
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2010
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1.51
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12
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Aerobic exercise overcomes the age-related insulin resistance of muscle protein metabolism by improving endothelial function and Akt/mammalian target of rapamycin signaling.
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2007
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1.50
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13
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An increase in essential amino acid availability upregulates amino acid transporter expression in human skeletal muscle.
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Am J Physiol Endocrinol Metab
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2010
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1.48
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14
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Blood flow restriction exercise stimulates mTORC1 signaling and muscle protein synthesis in older men.
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J Appl Physiol (1985)
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2010
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1.47
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15
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Effect of insulin on human skeletal muscle protein synthesis is modulated by insulin-induced changes in muscle blood flow and amino acid availability.
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Am J Physiol Endocrinol Metab
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2006
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1.46
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16
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Aging differentially affects human skeletal muscle microRNA expression at rest and after an anabolic stimulus of resistance exercise and essential amino acids.
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Am J Physiol Endocrinol Metab
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2008
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1.45
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17
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Aging and microRNA expression in human skeletal muscle: a microarray and bioinformatics analysis.
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Physiol Genomics
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2010
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1.43
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18
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Bed rest impairs skeletal muscle amino acid transporter expression, mTORC1 signaling, and protein synthesis in response to essential amino acids in older adults.
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Am J Physiol Endocrinol Metab
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2012
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1.41
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19
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Leucine-enriched nutrients and the regulation of mammalian target of rapamycin signalling and human skeletal muscle protein synthesis.
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Curr Opin Clin Nutr Metab Care
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2008
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1.34
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20
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Human muscle gene expression following resistance exercise and blood flow restriction.
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Med Sci Sports Exerc
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2008
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1.32
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21
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Insulin stimulates human skeletal muscle protein synthesis via an indirect mechanism involving endothelial-dependent vasodilation and mammalian target of rapamycin complex 1 signaling.
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J Clin Endocrinol Metab
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2010
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1.24
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22
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Essential amino acid and carbohydrate ingestion before resistance exercise does not enhance postexercise muscle protein synthesis.
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J Appl Physiol (1985)
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2008
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1.22
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23
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Muscle protein breakdown has a minor role in the protein anabolic response to essential amino acid and carbohydrate intake following resistance exercise.
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Am J Physiol Regul Integr Comp Physiol
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2010
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1.20
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24
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Essential amino acids increase microRNA-499, -208b, and -23a and downregulate myostatin and myocyte enhancer factor 2C mRNA expression in human skeletal muscle.
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J Nutr
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2009
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1.20
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25
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Expression of growth-related genes in young and older human skeletal muscle following an acute stimulation of protein synthesis.
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J Appl Physiol (1985)
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2008
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1.20
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26
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Basal muscle intracellular amino acid kinetics in women and men.
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Am J Physiol Endocrinol Metab
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2006
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1.18
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27
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Short-term insulin and nutritional energy provision do not stimulate muscle protein synthesis if blood amino acid availability decreases.
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Am J Physiol Endocrinol Metab
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2005
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1.14
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28
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Pharmacological vasodilation improves insulin-stimulated muscle protein anabolism but not glucose utilization in older adults.
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2010
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1.13
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29
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Skeletal muscle amino acid transporter expression is increased in young and older adults following resistance exercise.
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J Appl Physiol (1985)
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2011
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1.11
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30
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Skeletal muscle autophagy and protein breakdown following resistance exercise are similar in younger and older adults.
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J Gerontol A Biol Sci Med Sci
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2012
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1.09
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31
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Amino acids are necessary for the insulin-induced activation of mTOR/S6K1 signaling and protein synthesis in healthy and insulin resistant human skeletal muscle.
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Clin Nutr
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2008
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1.08
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32
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Reactive hyperemia is not responsible for stimulating muscle protein synthesis following blood flow restriction exercise.
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J Appl Physiol (1985)
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2012
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1.06
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33
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A moderate acute increase in physical activity enhances nutritive flow and the muscle protein anabolic response to mixed nutrient intake in older adults.
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Am J Clin Nutr
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2012
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1.06
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34
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Resistance exercise increases human skeletal muscle AS160/TBC1D4 phosphorylation in association with enhanced leg glucose uptake during postexercise recovery.
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J Appl Physiol (1985)
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2008
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1.02
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35
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Chronic paraplegia-induced muscle atrophy downregulates the mTOR/S6K1 signaling pathway.
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J Appl Physiol (1985)
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2007
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1.00
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36
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Exercise, amino acids, and aging in the control of human muscle protein synthesis.
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Med Sci Sports Exerc
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2011
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1.00
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37
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Short-term bed rest increases TLR4 and IL-6 expression in skeletal muscle of older adults.
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Am J Physiol Regul Integr Comp Physiol
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2013
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0.99
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38
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Protein blend ingestion following resistance exercise promotes human muscle protein synthesis.
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J Nutr
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2013
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0.97
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39
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Exercise and nutrition to target protein synthesis impairments in aging skeletal muscle.
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0.96
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40
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Resistance Exercise Training Alters Mitochondrial Function in Human Skeletal Muscle.
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Med Sci Sports Exerc
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0.93
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41
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Aging differentially affects human skeletal muscle amino acid transporter expression when essential amino acids are ingested after exercise.
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Clin Nutr
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0.91
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42
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A chronic increase in physical activity inhibits fed-state mTOR/S6K1 signaling and reduces IRS-1 serine phosphorylation in rat skeletal muscle.
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Appl Physiol Nutr Metab
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0.91
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43
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Skeletal muscle protein anabolic response to increased energy and insulin is preserved in poorly controlled type 2 diabetes.
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J Nutr
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0.91
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44
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Sequential muscle biopsies during a 6-h tracer infusion do not affect human mixed muscle protein synthesis and muscle phenylalanine kinetics.
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Am J Physiol Endocrinol Metab
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2008
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0.91
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45
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Gene and protein expression associated with protein synthesis and breakdown in paraplegic skeletal muscle.
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0.90
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46
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Deficiency in repair of the mitochondrial genome sensitizes proliferating myoblasts to oxidative damage.
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0.89
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47
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Skeletal muscle protein balance and metabolism in the elderly.
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0.87
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48
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Addition of carbohydrate or alanine to an essential amino acid mixture does not enhance human skeletal muscle protein anabolism.
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0.87
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49
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PAX7+ satellite cells in young and older adults following resistance exercise.
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0.85
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50
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Rapamycin does not affect post-absorptive protein metabolism in human skeletal muscle.
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51
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Leg glucose and protein metabolism during an acute bout of resistance exercise in humans.
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52
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Essential amino acid sensing, signaling, and transport in the regulation of human muscle protein metabolism.
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53
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Long-Term Skeletal Muscle Mitochondrial Dysfunction is Associated with Hypermetabolism in Severely Burned Children.
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54
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The balancing act between the cellular processes of protein synthesis and breakdown: exercise as a model to understand the molecular mechanisms regulating muscle mass.
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55
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Amino acid transporters in the regulation of human skeletal muscle protein metabolism.
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56
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Insulin increases mRNA abundance of the amino acid transporter SLC7A5/LAT1 via an mTORC1-dependent mechanism in skeletal muscle cells.
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Physiol Rep
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0.77
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57
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Does a reduction in anabolic signaling contribute to muscle wasting in chronic heart failure?
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The relationships between testosterone, body composition, and insulin resistance: a lesson from a case of extreme hyperandrogenism.
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