Published in EMBO Rep on September 17, 2010
Virus-encoded microRNAs. Virology (2011) 2.28
Viral microRNA targetome of KSHV-infected primary effusion lymphoma cell lines. Cell Host Microbe (2011) 2.13
Virus-encoded microRNAs: an overview and a look to the future. PLoS Pathog (2012) 1.80
Ago HITS-CLIP expands understanding of Kaposi's sarcoma-associated herpesvirus miRNA function in primary effusion lymphomas. PLoS Pathog (2012) 1.53
Clinical Manifestations of Kaposi Sarcoma Herpesvirus Lytic Activation: Multicentric Castleman Disease (KSHV-MCD) and the KSHV Inflammatory Cytokine Syndrome. Front Microbiol (2012) 1.25
miRNA regulation of BK polyomavirus replication during early infection. Proc Natl Acad Sci U S A (2013) 1.13
Increasing expression of microRNA 181 inhibits porcine reproductive and respiratory syndrome virus replication and has implications for controlling virus infection. J Virol (2012) 1.12
γ-Herpesvirus-encoded miRNAs and their roles in viral biology and pathogenesis. Curr Opin Virol (2013) 1.10
KSHV microRNAs mediate cellular transformation and tumorigenesis by redundantly targeting cell growth and survival pathways. PLoS Pathog (2013) 1.08
A Kaposi's sarcoma-associated herpesvirus microRNA and its variants target the transforming growth factor β pathway to promote cell survival. J Virol (2012) 1.06
Viral oncogenes, noncoding RNAs, and RNA splicing in human tumor viruses. Int J Biol Sci (2010) 1.05
Host microRNA regulation of human cytomegalovirus immediate early protein translation promotes viral latency. J Virol (2014) 1.04
Systemically circulating viral and tumor-derived microRNAs in KSHV-associated malignancies. PLoS Pathog (2013) 1.04
Virus-encoded microRNAs facilitate gammaherpesvirus latency and pathogenesis in vivo. MBio (2014) 1.04
Emerging themes from EBV and KSHV microRNA targets. Viruses (2012) 1.00
Kaposi's Sarcoma-Associated Herpesvirus microRNAs. Front Microbiol (2012) 0.96
Functions of Kaposi's sarcoma-associated herpesvirus microRNAs. Biochim Biophys Acta (2011) 0.95
HIV-1 Nef and KSHV oncogene K1 synergistically promote angiogenesis by inducing cellular miR-718 to regulate the PTEN/AKT/mTOR signaling pathway. Nucleic Acids Res (2014) 0.92
MicroRNAs and unusual small RNAs discovered in Kaposi's sarcoma-associated herpesvirus virions. J Virol (2012) 0.91
Cellular microRNAs 498 and 320d regulate herpes simplex virus 1 induction of Kaposi's sarcoma-associated herpesvirus lytic replication by targeting RTA. PLoS One (2013) 0.90
Looking at Kaposi's Sarcoma-Associated Herpesvirus-Host Interactions from a microRNA Viewpoint. Front Microbiol (2012) 0.90
A role for host activation-induced cytidine deaminase in innate immune defense against KSHV. PLoS Pathog (2013) 0.87
Kaposi's sarcoma-associated herpesvirus encodes a mimic of cellular miR-23. J Virol (2013) 0.87
Inhibition of Kaposi's sarcoma-associated herpesvirus lytic replication by HIV-1 Nef and cellular microRNA hsa-miR-1258. J Virol (2014) 0.87
KSHV-Encoded MicroRNAs: Lessons for Viral Cancer Pathogenesis and Emerging Concepts. Int J Cell Biol (2012) 0.86
Systematic analysis of a xenograft mice model for KSHV+ primary effusion lymphoma (PEL). PLoS One (2014) 0.85
The Role of microRNAs in the Pathogenesis of Herpesvirus Infection. Viruses (2016) 0.85
Sequence analysis of Kaposi sarcoma-associated herpesvirus (KSHV) microRNAs in patients with multicentric Castleman disease and KSHV-associated inflammatory cytokine syndrome. J Infect Dis (2012) 0.84
A KSHV microRNA Directly Targets G Protein-Coupled Receptor Kinase 2 to Promote the Migration and Invasion of Endothelial Cells by Inducing CXCR2 and Activating AKT Signaling. PLoS Pathog (2015) 0.84
Molecular biology of human herpesvirus 8: novel functions and virus-host interactions implicated in viral pathogenesis and replication. Recent Results Cancer Res (2014) 0.84
MicroRNA miR-21 attenuates human cytomegalovirus replication in neural cells by targeting Cdc25a. J Virol (2014) 0.83
Sphingosine kinase-2 maintains viral latency and survival for KSHV-infected endothelial cells. PLoS One (2014) 0.83
Cellular MicroRNA Let-7a Suppresses KSHV Replication through Targeting MAP4K4 Signaling Pathways. PLoS One (2015) 0.79
Viral miRNA targeting of bicistronic and polycistronic transcripts. Curr Opin Virol (2014) 0.79
Transmission of human herpesvirus type 8 infection within families in american indigenous populations from the Brazilian Amazon. J Infect Dis (2012) 0.78
Transcriptomic analysis of KSHV-infected primary oral fibroblasts: The role of interferon-induced genes in the latency of oncogenic virus. Oncotarget (2016) 0.78
Role of host microRNAs in Kaposi's sarcoma-associated herpesvirus pathogenesis. Viruses (2014) 0.78
HITS-CLIP and PAR-CLIP advance viral miRNA targetome analysis. Crit Rev Eukaryot Gene Expr (2014) 0.78
The SH3BGR/STAT3 Pathway Regulates Cell Migration and Angiogenesis Induced by a Gammaherpesvirus MicroRNA. PLoS Pathog (2016) 0.77
Chromatinization of the KSHV Genome During the KSHV Life Cycle. Cancers (Basel) (2015) 0.77
A Review of Human Herpesvirus 8, the Kaposi's Sarcoma-Associated Herpesvirus, in the Pediatric Population. J Pediatric Infect Dis Soc (2013) 0.77
A KSHV microRNA enhances viral latency and induces angiogenesis by targeting GRK2 to activate the CXCR2/AKT pathway. Oncotarget (2016) 0.76
Kaposi sarcoma herpesvirus pathogenesis. Philos Trans R Soc Lond B Biol Sci (2017) 0.76
Japanese Macaque Rhadinovirus Encodes a Viral MicroRNA Mimic of the miR-17 Family. J Virol (2016) 0.75
Reactivation and Lytic Replication of Kaposi's Sarcoma-Associated Herpesvirus: An Update. Front Microbiol (2017) 0.75
Viral MicroRNAs Identified in Human Dental Pulp. J Endod (2016) 0.75
HIV-1 Vpr Inhibits Kaposi's Sarcoma-Associated Herpesvirus Lytic Replication by Inducing MicroRNA miR-942-5p and Activating NF-κB Signaling. J Virol (2016) 0.75
MicroRNA miR-155 Is Necessary for Efficient Gammaherpesvirus Reactivation from Latency, but Not for Establishment of Latency. J Virol (2016) 0.75
A viral microRNA downregulates metastasis suppressor CD82 and induces cell invasion and angiogenesis by activating the c-Met signaling. Oncogene (2017) 0.75
MicroRNAs: genomics, biogenesis, mechanism, and function. Cell (2004) 198.59
The functions of animal microRNAs. Nature (2004) 64.85
MicroRNA targets in Drosophila. Genome Biol (2003) 23.59
Identification of microRNAs of the herpesvirus family. Nat Methods (2005) 12.98
Illuminating the silence: understanding the structure and function of small RNAs. Nat Rev Mol Cell Biol (2007) 6.11
Kaposi's sarcoma-associated herpesvirus expresses an array of viral microRNAs in latently infected cells. Proc Natl Acad Sci U S A (2005) 5.88
MicroRNAs expressed by herpes simplex virus 1 during latent infection regulate viral mRNAs. Nature (2008) 5.29
A combined computational and microarray-based approach identifies novel microRNAs encoded by human gamma-herpesviruses. RNA (2006) 4.47
Kinetics of Kaposi's sarcoma-associated herpesvirus gene expression. J Virol (1999) 4.20
Activation and centromeric localization of CCAAT/enhancer-binding proteins during the mitotic clonal expansion of adipocyte differentiation. Genes Dev (1999) 3.19
Identification of cellular genes targeted by KSHV-encoded microRNAs. PLoS Pathog (2007) 3.16
Roles of the NFI/CTF gene family in transcription and development. Gene (2000) 3.00
Suppression of immediate-early viral gene expression by herpesvirus-coded microRNAs: implications for latency. Proc Natl Acad Sci U S A (2008) 2.90
Nuclear factor 1 interacts with five DNA elements in the promoter region of the human cytomegalovirus major immediate early gene. EMBO J (1986) 2.62
KSHV infection and the pathogenesis of Kaposi's sarcoma. Annu Rev Pathol (2006) 2.61
Tandem array-based expression screens identify host mRNA targets of virus-encoded microRNAs. Nat Genet (2008) 2.42
Auto-activation of the rta gene of human herpesvirus-8/Kaposi's sarcoma-associated herpesvirus. J Gen Virol (2000) 2.17
Regulation of KSHV lytic switch protein expression by a virus-encoded microRNA: an evolutionary adaptation that fine-tunes lytic reactivation. Cell Host Microbe (2009) 2.15
Epigenetic regulation of Kaposi's sarcoma-associated herpesvirus latency by virus-encoded microRNAs that target Rta and the cellular Rbl2-DNMT pathway. J Virol (2010) 1.98
Small RNAs: regulators and guardians of the genome. J Cell Physiol (2007) 1.86
Pivotal advance: Kaposi's sarcoma-associated herpesvirus (KSHV)-encoded microRNA specifically induce IL-6 and IL-10 secretion by macrophages and monocytes. J Leukoc Biol (2010) 1.77
Herpesvirus lytic replication and the cell cycle: arresting new developments. J Virol (2001) 1.64
Latent and lytic Epstein-Barr virus replication strategies. Rev Med Virol (2004) 1.45
Lytic replication-associated protein (RAP) encoded by Kaposi sarcoma-associated herpesvirus causes p21CIP-1-mediated G1 cell cycle arrest through CCAAT/enhancer-binding protein-alpha. Proc Natl Acad Sci U S A (2002) 1.34
Systematic identification of cellular signals reactivating Kaposi sarcoma-associated herpesvirus. PLoS Pathog (2007) 1.32
Kaposi's sarcoma-associated herpesvirus ori-Lyt-dependent DNA replication: dual role of replication and transcription activator. J Virol (2006) 1.26
Mechanism of DNA replication in eukaryotic cells: cellular host factors stimulating adenovirus DNA replication. Gene (1999) 1.21
Transcription factors and DNA replication origin selection. Bioessays (2005) 1.05
Regulation of the Epstein-Barr viral immediate early BRLF1 promoter through a distal NF1 site. Arch Virol (1998) 0.87
Human herpesvirus 8 infections in patients with immunodeficiencies. Hum Pathol (2008) 0.84
IRF3 mediates a TLR3/TLR4-specific antiviral gene program. Immunity (2002) 6.85
Translation repression in human cells by microRNA-induced gene silencing requires RCK/p54. PLoS Biol (2006) 6.41
siRNA function in RNAi: a chemical modification analysis. RNA (2003) 4.93
RNAi in human cells: basic structural and functional features of small interfering RNA. Mol Cell (2002) 3.81
Specific and potent RNAi in the nucleus of human cells. Nat Struct Mol Biol (2005) 3.16
Cellular microRNA and P bodies modulate host-HIV-1 interactions. Mol Cell (2009) 3.05
Small RNA-mediated regulation of iPS cell generation. EMBO J (2011) 2.95
Small-molecule inhibition of HIV-1 Vif. Nat Biotechnol (2008) 2.83
RNA helicase A interacts with RISC in human cells and functions in RISC loading. Mol Cell (2007) 2.72
Human retroviral host restriction factors APOBEC3G and APOBEC3F localize to mRNA processing bodies. PLoS Pathog (2006) 2.61
Closed-loop control of cellular functions using combinatory drugs guided by a stochastic search algorithm. Proc Natl Acad Sci U S A (2008) 2.22
NF-kappaB inhibits gammaherpesvirus lytic replication. J Virol (2003) 2.15
Fluorescent imaging of single nanoparticles and viruses on a smart phone. ACS Nano (2013) 2.14
Visualizing a correlation between siRNA localization, cellular uptake, and RNAi in living cells. Chem Biol (2004) 2.05
Hypercholesterolemia impairs the myocardial angiogenic response in a swine model of chronic ischemia: role of endostatin and oxidative stress. Ann Thorac Surg (2006) 2.02
Identification of viral genes essential for replication of murine gamma-herpesvirus 68 using signature-tagged mutagenesis. Proc Natl Acad Sci U S A (2005) 1.98
Transcription program of murine gammaherpesvirus 68. J Virol (2003) 1.96
Small RNAs: regulators and guardians of the genome. J Cell Physiol (2007) 1.86
Characterization of interactions between RTA and the promoter of polyadenylated nuclear RNA in Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8. J Virol (2002) 1.83
Target accessibility dictates the potency of human RISC. Nat Struct Mol Biol (2005) 1.78
The long noncoding RNA THRIL regulates TNFα expression through its interaction with hnRNPL. Proc Natl Acad Sci U S A (2013) 1.78
Identification of proteins associated with murine gammaherpesvirus 68 virions. J Virol (2003) 1.75
Discovery of alogliptin: a potent, selective, bioavailable, and efficacious inhibitor of dipeptidyl peptidase IV. J Med Chem (2007) 1.73
Changing malaria transmission and implications in China towards National Malaria Elimination Programme between 2010 and 2012. PLoS One (2013) 1.72
Gamma-herpesvirus kinase actively initiates a DNA damage response by inducing phosphorylation of H2AX to foster viral replication. Cell Host Microbe (2007) 1.71
The effects of therapeutic sulfide on myocardial apoptosis in response to ischemia-reperfusion injury. Eur J Cardiothorac Surg (2008) 1.68
High-dose atorvastatin is associated with impaired myocardial angiogenesis in response to vascular endothelial growth factor in hypercholesterolemic swine. J Thorac Cardiovasc Surg (2006) 1.66
Three-dimensional visualization of gammaherpesvirus life cycle in host cells by electron tomography. Structure (2010) 1.65
Safety and efficacy of a novel gel for vascular occlusion in off-pump surgery. Ann Thorac Surg (2005) 1.61
Transcriptional regulation of the interleukin-6 gene of human herpesvirus 8 (Kaposi's sarcoma-associated herpesvirus). J Virol (2002) 1.60
PowerMV: a software environment for molecular viewing, descriptor generation, data analysis and hit evaluation. J Chem Inf Model (2005) 1.54
Quantitative imaging of single, unstained viruses with coherent x rays. Phys Rev Lett (2008) 1.52
Functional, cellular, and molecular characterization of the angiogenic response to chronic myocardial ischemia in diabetes. Circulation (2007) 1.47
The frameshift signal of HIV-1 involves a potential intramolecular triplex RNA structure. Proc Natl Acad Sci U S A (2002) 1.46
TAR RNA loop: a scaffold for the assembly of a regulatory switch in HIV replication. Proc Natl Acad Sci U S A (2002) 1.44
HIV-1 protease inhibitors from inverse design in the substrate envelope exhibit subnanomolar binding to drug-resistant variants. J Am Chem Soc (2008) 1.43
Tat stimulates cotranscriptional capping of HIV mRNA. Mol Cell (2002) 1.43
Analysis of HIV-1 viral infectivity factor-mediated proteasome-dependent depletion of APOBEC3G: correlating function and subcellular localization. J Biol Chem (2004) 1.42
Effect of sodium tanshinone II A sulfonate on phosphorylation of extracellular signal-regulated kinase 1/2 in angiotensin II-induced hypertrophy of myocardial cells. Chin J Integr Med (2008) 1.40
Murine gammaherpesvirus 68 open reading frame 31 is required for viral replication. J Virol (2004) 1.40
The new face of the old molecules: crustin Pm4 and transglutaminase type I serving as rnps down-regulate astakine-mediated hematopoiesis. PLoS One (2013) 1.40
Evaluating the substrate-envelope hypothesis: structural analysis of novel HIV-1 protease inhibitors designed to be robust against drug resistance. J Virol (2010) 1.39
Resveratrol improves myocardial perfusion in a swine model of hypercholesterolemia and chronic myocardial ischemia. Circulation (2010) 1.37
Comparative study of regulation of RTA-responsive genes in Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8. J Virol (2003) 1.36
Persistent gammaherpesvirus replication and dynamic interaction with the host in vivo. J Virol (2008) 1.36
Systematic identification of cellular signals reactivating Kaposi sarcoma-associated herpesvirus. PLoS Pathog (2007) 1.32
Viral Bcl-2-mediated evasion of autophagy aids chronic infection of gammaherpesvirus 68. PLoS Pathog (2009) 1.31
Kaposi's sarcoma-associated herpesvirus encoded vFLIP induces cellular IL-6 expression: the role of the NF-kappaB and JNK/AP1 pathways. Oncogene (2003) 1.31
Conserved herpesviral kinase promotes viral persistence by inhibiting the IRF-3-mediated type I interferon response. Cell Host Microbe (2009) 1.30
High-resolution functional profiling of hepatitis C virus genome. PLoS Pathog (2008) 1.30
Potent RNAi by short RNA triggers. RNA (2008) 1.29
Hydrogen sulfide therapy attenuates the inflammatory response in a porcine model of myocardial ischemia/reperfusion injury. J Thorac Cardiovasc Surg (2009) 1.27
Deep annotation of mouse iso-miR and iso-moR variation. Nucleic Acids Res (2012) 1.27
Overfed Ossabaw swine with early stage metabolic syndrome have normal coronary collateral development in response to chronic ischemia. Basic Res Cardiol (2012) 1.26
Thymidine kinase 2 mutations in autosomal recessive progressive external ophthalmoplegia with multiple mitochondrial DNA deletions. Hum Mol Genet (2011) 1.26
Inhibition of human immunodeficiency virus type 1 replication by RNA interference directed against human transcription elongation factor P-TEFb (CDK9/CyclinT1). J Virol (2004) 1.26
ORF18 is a transfactor that is essential for late gene transcription of a gammaherpesvirus. J Virol (2006) 1.24
[Malaria situation in the People's Republic of China in 2012]. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi (2013) 1.23
The heat shock protein inhibitor Quercetin attenuates hepatitis C virus production. Hepatology (2009) 1.21
Specific HIV-1 TAR RNA loop sequence and functional groups are required for human cyclin T1-Tat-TAR ternary complex formation. Biochemistry (2002) 1.21
Rta of the human herpesvirus 8/Kaposi sarcoma-associated herpesvirus up-regulates human interleukin-6 gene expression. Blood (2002) 1.20
microRNAs modulate iPS cell generation. RNA (2011) 1.19
Calcium-activated potassium channels contribute to human skeletal muscle microvascular endothelial dysfunction related to cardiopulmonary bypass. Surgery (2008) 1.18
Protein kinase C alpha modulates microvascular reactivity in the human coronary and skeletal microcirculation. Surgery (2007) 1.17
Discovery of HIV-1 protease inhibitors with picomolar affinities incorporating N-aryl-oxazolidinone-5-carboxamides as novel P2 ligands. J Med Chem (2006) 1.17
Design and creation of new nanomaterials for therapeutic RNAi. ACS Chem Biol (2007) 1.16
B cell terminal differentiation factor XBP-1 induces reactivation of Kaposi's sarcoma-associated herpesvirus. FEBS Lett (2007) 1.16
ORF30 and ORF34 are essential for expression of late genes in murine gammaherpesvirus 68. J Virol (2008) 1.14
Murine gamma-herpesvirus 68 hijacks MAVS and IKKbeta to initiate lytic replication. PLoS Pathog (2010) 1.14
A kinase inhibitor screen identifies small-molecule enhancers of reprogramming and iPS cell generation. Nat Commun (2012) 1.14
Label-free, electrical detection of the SARS virus N-protein with nanowire biosensors utilizing antibody mimics as capture probes. ACS Nano (2009) 1.14
Identification of cis sequences required for lytic DNA replication and packaging of murine gammaherpesvirus 68. J Virol (2004) 1.13
Design of mutation-resistant HIV protease inhibitors with the substrate envelope hypothesis. Chem Biol Drug Des (2007) 1.12
Discovery of a small molecule Tat-trans-activation-responsive RNA antagonist that potently inhibits human immunodeficiency virus-1 replication. J Biol Chem (2003) 1.11
C-Reactive protein and inflammatory response associated to neurocognitive decline following cardiac surgery. Surgery (2006) 1.11
Murine gammaherpesvirus 68 open reading frame 24 is required for late gene expression after DNA replication. J Virol (2007) 1.11
Effect of hydrogen sulfide in a porcine model of myocardial ischemia-reperfusion: comparison of different administration regimens and characterization of the cellular mechanisms of protection. J Cardiovasc Pharmacol (2009) 1.11
Effect of hypercholesterolemia on myocardial necrosis and apoptosis in the setting of ischemia-reperfusion. Circulation (2009) 1.10
An integrated microfluidic array system for evaluating toxicity and teratogenicity of drugs on embryonic zebrafish developmental dynamics. Biomicrofluidics (2011) 1.10
Microfluidic device architecture for electrochemical patterning and detection of multiple DNA sequences. Langmuir (2008) 1.09
Early establishment of gamma-herpesvirus latency: implications for immune control. J Immunol (2005) 1.09
Genetic analysis of H1N1 influenza virus from throat swab samples in a microfluidic system for point-of-care diagnostics. J Am Chem Soc (2011) 1.09
Imported malaria in China, 2012. Emerg Infect Dis (2014) 1.09
Inhibition of gammaherpesvirus replication by RNA interference. J Virol (2003) 1.08
beta-Adrenoreceptors reactivate Kaposi's sarcoma-associated herpesvirus lytic replication via PKA-dependent control of viral RTA. J Virol (2005) 1.08
Resveratrol modifies risk factors for coronary artery disease in swine with metabolic syndrome and myocardial ischemia. Eur J Pharmacol (2011) 1.08
Two kinetic patterns of epitope-specific CD8 T-cell responses following murine gammaherpesvirus 68 infection. J Virol (2010) 1.08
Discovery of nonsteroidal anti-inflammatory drug and anticancer drug enhancing reprogramming and induced pluripotent stem cell generation. Stem Cells (2011) 1.08
Systematic identification of H274Y compensatory mutations in influenza A virus neuraminidase by high-throughput screening. J Virol (2012) 1.07
Complete genome sequence of Bacillus amyloliquefaciens LL3, which exhibits glutamic acid-independent production of poly-γ-glutamic acid. J Bacteriol (2011) 1.07
Dissecting RNA-interference pathway with small molecules. Chem Biol (2005) 1.07
mRNA display selection of a high-affinity, modification-specific phospho-IkappaBalpha-binding fibronectin. ACS Chem Biol (2008) 1.07