Published in J Endocrinol on September 27, 2010
Nuclear receptors in bone physiology and diseases. Physiol Rev (2013) 0.86
Zebrafish vitamin K epoxide reductases: expression in vivo, along extracellular matrix mineralization and under phylloquinone and warfarin in vitro exposure. Fish Physiol Biochem (2015) 0.76
Effect of vitamin K2 on the development of stress-induced osteopenia in a growing senescence-accelerated mouse prone 6 strain. Exp Ther Med (2015) 0.75
PXR variants: the impact on drug metabolism and therapeutic responses. Acta Pharm Sin B (2016) 0.75
Pregnane X receptor knockout mice display aging-dependent wearing of articular cartilage. PLoS One (2015) 0.75
Spontaneous calcification of arteries and cartilage in mice lacking matrix GLA protein. Nature (1997) 7.10
The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity. Proc Natl Acad Sci U S A (2001) 4.58
SXR, a novel steroid and xenobiotic-sensing nuclear receptor. Genes Dev (1998) 4.19
The orphan nuclear receptor SXR coordinately regulates drug metabolism and efflux. Nat Med (2001) 3.45
Humanized xenobiotic response in mice expressing nuclear receptor SXR. Nature (2000) 3.41
Characterization of a gamma-carboxyglutamic acid-containing protein from bone. Proc Natl Acad Sci U S A (1976) 3.15
Vitamin K and the prevention of fractures: systematic review and meta-analysis of randomized controlled trials. Arch Intern Med (2006) 3.05
A microtomographic system for the nondestructive evaluation of bone architecture. Calcif Tissue Int (1996) 2.98
Selective inhibition of NF-kappa B blocks osteoclastogenesis and prevents inflammatory bone destruction in vivo. Nat Med (2004) 2.94
Inhibition of osteoblastic bone formation by nuclear factor-kappaB. Nat Med (2009) 2.51
Mutual repression between steroid and xenobiotic receptor and NF-kappaB signaling pathways links xenobiotic metabolism and inflammation. J Clin Invest (2006) 2.28
Role of NF-kappaB in regulation of PXR-mediated gene expression: a mechanism for the suppression of cytochrome P-450 3A4 by proinflammatory agents. J Biol Chem (2006) 2.04
Steroid and xenobiotic receptor and vitamin D receptor crosstalk mediates CYP24 expression and drug-induced osteomalacia. J Clin Invest (2006) 1.75
Vitamin K2 (menatetrenone) effectively prevents fractures and sustains lumbar bone mineral density in osteoporosis. J Bone Miner Res (2000) 1.71
Vitamin K2 regulation of bone homeostasis is mediated by the steroid and xenobiotic receptor SXR. J Biol Chem (2003) 1.69
Expression of the drug transporters MDR1/ABCB1, MRP1/ABCC1, MRP2/ABCC2, BCRP/ABCG2, and PXR in peripheral blood mononuclear cells and their relationship with the expression in intestine and liver. Biochem Pharmacol (2005) 1.52
The steroid and xenobiotic receptor (SXR), beyond xenobiotic metabolism. Nucl Recept Signal (2009) 1.41
Steroid and xenobiotic receptor SXR mediates vitamin K2-activated transcription of extracellular matrix-related genes and collagen accumulation in osteoblastic cells. J Biol Chem (2006) 1.33
Retracted Vitamin K induces osteoblast differentiation through pregnane X receptor-mediated transcriptional control of the Msx2 gene. Mol Cell Biol (2007) 1.32
Healing of bone disease in X-linked hypophosphatemic rickets/osteomalacia. Induction and maintenance with phosphorus and calcitriol. J Clin Invest (1985) 1.24
Steroid and xenobiotic receptor (SXR), cytochrome P450 3A4 and multidrug resistance gene 1 in human adult and fetal tissues. Mol Cell Endocrinol (2005) 1.15
A versatile new mineralized bone stain for simultaneous assessment of tetracycline and osteoid seams. Stain Technol (1989) 1.08
Vitamin K2 suppresses proliferation and motility of hepatocellular carcinoma cells by activating steroid and xenobiotic receptor. Endocr J (2009) 0.95
Nuclear xenobiotic receptor PXR-null mouse exhibits hypophosphatemia and represses the Na/Pi-cotransporter SLC34A2. Pharmacogenet Genomics (2010) 0.81
TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity. Nature (2007) 8.87
The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line. Nat Genet (2009) 6.02
Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-I. Cell Host Microbe (2009) 5.12
Buonocore memorial lecture. Adhesion to enamel and dentin: current status and future challenges. Oper Dent (2003) 4.75
The genome of the Western clawed frog Xenopus tropicalis. Science (2010) 4.70
Targeted ablation of osteocytes induces osteoporosis with defective mechanotransduction. Cell Metab (2007) 4.64
The dynamic genome of Hydra. Nature (2010) 4.00
Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production. Nat Immunol (2009) 3.58
Endocrine disrupters as obesogens. Mol Cell Endocrinol (2009) 2.80
Environmental obesogens: organotins and endocrine disruption via nuclear receptor signaling. Endocrinology (2006) 2.56
Formation of plexiform lesions in experimental severe pulmonary arterial hypertension. Circulation (2010) 2.43
Endocrine-disrupting organotin compounds are potent inducers of adipogenesis in vertebrates. Mol Endocrinol (2006) 2.41
Efp targets 14-3-3 sigma for proteolysis and promotes breast tumour growth. Nature (2002) 2.32
Improvement of cancer-targeting therapy, using nanocarriers for intractable solid tumors by inhibition of TGF-beta signaling. Proc Natl Acad Sci U S A (2007) 2.30
Mutual repression between steroid and xenobiotic receptor and NF-kappaB signaling pathways links xenobiotic metabolism and inflammation. J Clin Invest (2006) 2.28
Endocrine disrupting chemicals and disease susceptibility. J Steroid Biochem Mol Biol (2011) 2.28
Sirt1 modulates premature senescence-like phenotype in human endothelial cells. J Mol Cell Cardiol (2007) 2.22
Clinical use of quantitative computed tomography and peripheral quantitative computed tomography in the management of osteoporosis in adults: the 2007 ISCD Official Positions. J Clin Densitom (2008) 2.21
Highly chlorinated PCBs inhibit the human xenobiotic response mediated by the steroid and xenobiotic receptor (SXR). Environ Health Perspect (2004) 2.16
Transgenerational inheritance of increased fat depot size, stem cell reprogramming, and hepatic steatosis elicited by prenatal exposure to the obesogen tributyltin in mice. Environ Health Perspect (2013) 2.12
D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function. Genes Dev (2012) 2.10
Cilostazol inhibits oxidative stress-induced premature senescence via upregulation of Sirt1 in human endothelial cells. Arterioscler Thromb Vasc Biol (2008) 2.07
Isoform-specific p73 knockout mice reveal a novel role for delta Np73 in the DNA damage response pathway. Genes Dev (2010) 2.06
Inhibition of brain tumor growth by intravenous poly (β-L-malic acid) nanobioconjugate with pH-dependent drug release [corrected]. Proc Natl Acad Sci U S A (2010) 2.05
Clinical features and management issues in Mowat-Wilson syndrome. Am J Med Genet A (2006) 1.97
Perturbed nuclear receptor signaling by environmental obesogens as emerging factors in the obesity crisis. Rev Endocr Metab Disord (2007) 1.96
Estrogen regulates tumor growth through a nonclassical pathway that includes the transcription factors ERβ and KLF5. Sci Signal (2011) 1.88
Inhibitory effects of novel AP-1 decoy oligodeoxynucleotides on vascular smooth muscle cell proliferation in vitro and neointimal formation in vivo. Circ Res (2002) 1.87
Prenatal exposure to the environmental obesogen tributyltin predisposes multipotent stem cells to become adipocytes. Mol Endocrinol (2010) 1.84
Steroid and xenobiotic receptor and vitamin D receptor crosstalk mediates CYP24 expression and drug-induced osteomalacia. J Clin Invest (2006) 1.75
Randomized Teriparatide [human parathyroid hormone (PTH) 1-34] Once-Weekly Efficacy Research (TOWER) trial for examining the reduction in new vertebral fractures in subjects with primary osteoporosis and high fracture risk. J Clin Endocrinol Metab (2012) 1.74
Coordination of PGC-1beta and iron uptake in mitochondrial biogenesis and osteoclast activation. Nat Med (2009) 1.72
Osteoclast-secreted CTHRC1 in the coupling of bone resorption to formation. J Clin Invest (2013) 1.70
Klotho gene polymorphisms associated with bone density of aged postmenopausal women. J Bone Miner Res (2002) 1.69
Vitamin K2 regulation of bone homeostasis is mediated by the steroid and xenobiotic receptor SXR. J Biol Chem (2003) 1.69
Predicting later-life outcomes of early-life exposures. Environ Health Perspect (2012) 1.67
Triflumizole is an obesogen in mice that acts through peroxisome proliferator activated receptor gamma (PPARγ). Environ Health Perspect (2012) 1.63
VEGF-A and FGF-2 synergistically promote neoangiogenesis through enhancement of endogenous PDGF-B-PDGFRbeta signaling. J Cell Sci (2005) 1.61
Primary role of functional ischemia, quantitative evidence for the two-hit mechanism, and phosphodiesterase-5 inhibitor therapy in mouse muscular dystrophy. PLoS One (2007) 1.60
Association of low testosterone with metabolic syndrome and its components in middle-aged Japanese men. Hypertens Res (2010) 1.57
Osteoclast-derived complement component 3a stimulates osteoblast differentiation. J Bone Miner Res (2014) 1.56
Runx2 determines bone maturity and turnover rate in postnatal bone development and is involved in bone loss in estrogen deficiency. Dev Dyn (2007) 1.56
A new active vitamin D3 analog, eldecalcitol, prevents the risk of osteoporotic fractures--a randomized, active comparator, double-blind study. Bone (2011) 1.55
A retrovirus restriction factor TRIM5alpha is transcriptionally regulated by interferons. Biochem Biophys Res Commun (2005) 1.54
New modes of action for endocrine-disrupting chemicals. Mol Endocrinol (2005) 1.54
Identification of multiple novel epididymis-specific beta-defensin isoforms in humans and mice. J Immunol (2002) 1.53
De novo formation and rupture of an aneurysm. Case report. J Neurosurg (2002) 1.52
Endocrine disrupting chemicals and the developmental programming of adipogenesis and obesity. Birth Defects Res C Embryo Today (2011) 1.52
Prevalence of metabolic syndrome in the general Japanese population in 2000. J Atheroscler Thromb (2006) 1.50
Androgen-responsive long noncoding RNA CTBP1-AS promotes prostate cancer. EMBO J (2013) 1.48
The dietary isothiocyanate sulforaphane is an antagonist of the human steroid and xenobiotic nuclear receptor. Mol Pharmacol (2006) 1.47
Increased plasma interleukin-6 is associated with the pathogenesis of obstructive sleep apnea syndrome. Chest (2004) 1.47
TAp73 depletion accelerates aging through metabolic dysregulation. Genes Dev (2012) 1.45
Olanzapine-induced delirium in a terminally ill cancer patient. J Pain Symptom Manage (2004) 1.45
GPR98/Gpr98 gene is involved in the regulation of human and mouse bone mineral density. J Clin Endocrinol Metab (2012) 1.44
Increased plasma morphine metabolites in terminally ill cancer patients with delirium: an intra-individual comparison. J Pain Symptom Manage (2002) 1.44
Retracted Effect of nasal continuous positive airway pressure treatment on plasma adrenomedullin levels in patients with obstructive sleep apnea syndrome: roles of nocturnal hypoxia and oxidant stress. Hypertens Res (2007) 1.43
Science and policy on endocrine disrupters must not be mixed: a reply to a "common sense" intervention by toxicology journal editors. Environ Health (2013) 1.42
The steroid and xenobiotic receptor (SXR), beyond xenobiotic metabolism. Nucl Recept Signal (2009) 1.41
Minireview: PPARγ as the target of obesogens. J Steroid Biochem Mol Biol (2011) 1.40
Genome-wide single nucleotide polymorphism typing method for identification of Bacillus anthracis species and strains among B. cereus group species. J Clin Microbiol (2010) 1.38
Effects of obstructive sleep apnea on circulating ICAM-1, IL-8, and MCP-1. J Appl Physiol (1985) (2002) 1.38
A pivotal role of cytosolic phospholipase A(2) in bleomycin-induced pulmonary fibrosis. Nat Med (2002) 1.35
mda-7/IL-24, novel anticancer cytokine: focus on bystander antitumor, radiosensitization and antiangiogenic properties and overview of the phase I clinical experience (Review). Int J Oncol (2007) 1.34
Minireview: the case for obesogens. Mol Endocrinol (2009) 1.33
Steroid and xenobiotic receptor SXR mediates vitamin K2-activated transcription of extracellular matrix-related genes and collagen accumulation in osteoblastic cells. J Biol Chem (2006) 1.33
Targeted gene expression using the GAL4/UAS system in the silkworm Bombyx mori. Genetics (2003) 1.31
Long-term treatment of incadronate disodium accumulates microdamage but improves the trabecular bone microarchitecture in dog vertebra. J Bone Miner Res (2003) 1.31
BRCA1 interacts with Nrf2 to regulate antioxidant signaling and cell survival. J Exp Med (2013) 1.30
Technique-sensitivity of contemporary adhesives. Dent Mater J (2005) 1.30
A stabilizing factor for mitochondrial respiratory supercomplex assembly regulates energy metabolism in muscle. Nat Commun (2013) 1.29
Learning from and about others: towards using imitation to bootstrap the social understanding of others by robots. Artif Life (2005) 1.28
A simple and rapid immunochromatographic test kit for rabies diagnosis. Microbiol Immunol (2008) 1.27
Phenotype and genotype characteristics of age-related macular degeneration in a Japanese population. Ophthalmology (2010) 1.26
Expression of the steroid and xenobiotic receptor and its possible target gene, organic anion transporting polypeptide-A, in human breast carcinoma. Cancer Res (2006) 1.26
SIRT1/eNOS axis as a potential target against vascular senescence, dysfunction and atherosclerosis. J Atheroscler Thromb (2010) 1.25
Statins protect human aortic smooth muscle cells from inorganic phosphate-induced calcification by restoring Gas6-Axl survival pathway. Circ Res (2006) 1.24
Nuclear cyclin B1 in human breast carcinoma as a potent prognostic factor. Cancer Sci (2007) 1.24
The obesogenic effect of high fructose exposure during early development. Nat Rev Endocrinol (2013) 1.23
Amyloid precursor protein is a primary androgen target gene that promotes prostate cancer growth. Cancer Res (2009) 1.20
17Beta-estradiol protects against oxidative stress-induced cell death through the glutathione/glutaredoxin-dependent redox regulation of Akt in myocardiac H9c2 cells. J Biol Chem (2006) 1.20
Survival versus apoptotic 17beta-estradiol effect: role of ER alpha and ER beta activated non-genomic signaling. J Cell Physiol (2005) 1.18
Estrogen receptors and their downstream targets in cancer. Arch Histol Cytol (2004) 1.18
The environmental obesogen tributyltin chloride acts via peroxisome proliferator activated receptor gamma to induce adipogenesis in murine 3T3-L1 preadipocytes. J Steroid Biochem Mol Biol (2011) 1.17
Estrogen receptor-associated expression of keratinocyte growth factor and its possible role in the inhibition of apoptosis in human breast cancer. Lab Invest (2004) 1.17
Gas6/Axl-PI3K/Akt pathway plays a central role in the effect of statins on inorganic phosphate-induced calcification of vascular smooth muscle cells. Eur J Pharmacol (2006) 1.16
Decreased expression of 14-3-3 sigma is associated with advanced disease in human epithelial ovarian cancer: its correlation with aberrant DNA methylation. Clin Cancer Res (2004) 1.16