PubRank

Changsheng Zhang

Author PubWeight™ 44.42‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Expanding the promiscuity of a natural-product glycosyltransferase by directed evolution. Nat Chem Biol 2007 2.31
2 Optimizing glycosyltransferase specificity via "hot spot" saturation mutagenesis presents a catalyst for novobiocin glycorandomization. Chem Biol 2008 1.84
3 Recombinant E. coli prototype strains for in vivo glycorandomization. ACS Chem Biol 2010 1.82
4 Antibiotic optimization via in vitro glycorandomization. Nat Biotechnol 2003 1.41
5 Substrate specificity of the macrolide-glycosylating enzyme pair DesVII/DesVIII: opportunities, limitations, and mechanistic hypotheses. Angew Chem Int Ed Engl 2006 1.27
6 Deciphering indolocarbazole and enediyne aminodideoxypentose biosynthesis through comparative genomics: insights from the AT2433 biosynthetic locus. Chem Biol 2006 1.15
7 Structure and mechanism of the rebeccamycin sugar 4'-O-methyltransferase RebM. J Biol Chem 2008 1.12
8 Spiroindimicins A-D: new bisindole alkaloids from a deep-sea-derived actinomycete. Org Lett 2012 1.00
9 Pseudonocardians A-C, new diazaanthraquinone derivatives from a deap-sea actinomycete Pseudonocardia sp. SCSIO 01299. Mar Drugs 2011 0.98
10 Mechanistic insights into polycycle formation by reductive cyclization in ikarugamycin biosynthesis. Angew Chem Int Ed Engl 2014 0.97
11 Structural insight into the self-sacrifice mechanism of enediyne resistance. ACS Chem Biol 2006 0.96
12 Characterization of the amicetin biosynthesis gene cluster from Streptomyces vinaceusdrappus NRRL 2363 implicates two alternative strategies for amide bond formation. Appl Environ Microbiol 2012 0.95
13 Diversifying vancomycin via chemoenzymatic strategies. Org Lett 2005 0.94
14 Characterization of tiacumicin B biosynthetic gene cluster affording diversified tiacumicin analogues and revealing a tailoring dihalogenase. J Am Chem Soc 2010 0.94
15 Antimalarial β-carboline and indolactam alkaloids from Marinactinospora thermotolerans, a deep sea isolate. J Nat Prod 2011 0.92
16 Cloning and characterization of the biosynthetic gene cluster of the bacterial RNA polymerase inhibitor tirandamycin from marine-derived Streptomyces sp. SCSIO1666. Biochem Biophys Res Commun 2011 0.92
17 Identification and characterization of xiamycin A and oxiamycin gene cluster reveals an oxidative cyclization strategy tailoring indolosesquiterpene biosynthesis. J Am Chem Soc 2012 0.91
18 Lobophorins E and F, new spirotetronate antibiotics from a South China Sea-derived Streptomyces sp. SCSIO 01127. J Antibiot (Tokyo) 2011 0.91
19 Biosynthesis of himastatin: assembly line and characterization of three cytochrome P450 enzymes involved in the post-tailoring oxidative steps. Angew Chem Int Ed Engl 2011 0.90
20 Cytotoxic angucycline class glycosides from the deep sea actinomycete Streptomyces lusitanus SCSIO LR32. J Nat Prod 2012 0.89
21 Predicting kinetic constants of protein-protein interactions based on structural properties. Proteins 2010 0.89
22 New diketopiperazine derivatives from a deep-sea-derived Nocardiopsis alba SCSIO 03039. J Antibiot (Tokyo) 2012 0.88
23 Δ(11,12) double bond formation in tirandamycin biosynthesis is atypically catalyzed by TrdE, a glycoside hydrolase family enzyme. J Am Chem Soc 2012 0.87
24 Characterization of TrdL as a 10-hydroxy dehydrogenase and generation of new analogues from a tirandamycin biosynthetic pathway. Org Lett 2011 0.87
25 Dissecting glycosylation steps in lobophorin biosynthesis implies an iterative glycosyltransferase. Org Lett 2013 0.87
26 Antibacterial and cytotoxic new napyradiomycins from the marine-derived Streptomyces sp. SCSIO 10428. Mar Drugs 2013 0.84
27 Characterizing amosamine biosynthesis in amicetin reveals AmiG as a reversible retaining glycosyltransferase. J Am Chem Soc 2013 0.84
28 Characterization of a single gene cluster responsible for methylpendolmycin and pendolmycin biosynthesis in the deep sea bacterium Marinactinospora thermotolerans. Chembiochem 2012 0.84
29 Engineering a zinc binding site into the de novo designed protein DS119 with a βαβ structure. Protein Cell 2012 0.83
30 Carboxyl formation from methyl via triple hydroxylations by XiaM in xiamycin A biosynthesis. Org Lett 2012 0.83
31 Maturation mechanism of severe acute respiratory syndrome (SARS) coronavirus 3C-like proteinase. J Biol Chem 2010 0.82
32 Discovery and engineered overproduction of antimicrobial nucleoside antibiotic A201A from the deep-sea marine actinomycete Marinactinospora thermotolerans SCSIO 00652. Antimicrob Agents Chemother 2011 0.81
33 Fluostatins I-K from the South China Sea-derived micromonospora rosaria SCSIO N160. J Nat Prod 2012 0.81
34 Nocardiamides A and B, two cyclohexapeptides from the marine-derived actinomycete Nocardiopsis sp. CNX037. J Nat Prod 2013 0.81
35 Characterization of the sugar-O-methyltransferase LobS1 in lobophorin biosynthesis. Appl Microbiol Biotechnol 2013 0.80
36 Spine Bull's-Eye Robot guidewire placement with pedicle standard axis view for thoracic and lumbar pedicle screw fixation. J Spinal Disord Tech 2012 0.80
37 Hyperbaric oxygen preconditioning attenuates postoperative cognitive impairment in aged rats. Neuroreport 2014 0.78
38 [Genetic manipulation system for tiacumicin producer Dactylosporangium aurantiacum NRRL 18085]. Wei Sheng Wu Xue Bao 2010 0.78
39 [Isolation and structural elucidation of secondary metabolites from marine Streptomyces sp. SCSIO 1934]. Zhongguo Zhong Yao Za Zhi 2011 0.78
40 Elucidating the cyclization cascades in xiamycin biosynthesis by substrate synthesis and enzyme characterizations. Org Lett 2014 0.78
41 Characterization of a sugar-O-methyltransferase TiaS5 affords new Tiacumicin analogues with improved antibacterial properties and reveals substrate promiscuity. Chembiochem 2011 0.77
42 Elucidating hydroxylation and methylation steps tailoring piericidin A1 biosynthesis. Org Lett 2014 0.77
43 Insights into caerulomycin A biosynthesis: a two-component monooxygenase CrmH-catalyzed oxime formation. J Am Chem Soc 2013 0.76
44 Identification of caerulomycin A gene cluster implicates a tailoring amidohydrolase. Org Lett 2012 0.76
45 Preliminary X-ray crystallographic analysis of the glycosyltransferase from a marine Streptomyces species. Acta Crystallogr Sect F Struct Biol Cryst Commun 2010 0.75
46 Correction: measurement and analysis of the tracheobronchial tree in chinese population using computed tomography. PLoS One 2015 0.75
47 Heronamides D-F, polyketide macrolactams from the deep-sea-derived Streptomyces sp. SCSIO 03032. J Nat Prod 2014 0.75
48 Penicacids A-C, three new mycophenolic acid derivatives and immunosuppressive activities from the marine-derived fungus Penicillium sp. SOF07. Bioorg Med Chem Lett 2012 0.75
49 [Development of a genetic modification system for caerulomycin producer Actinoalloteichus sp. WH1-2216-6]. Wei Sheng Wu Xue Bao 2011 0.75
50 Applying Distributed Constraint Optimization Approach to the User Association Problem in Heterogeneous Networks. IEEE Trans Cybern 2017 0.75
51 Transpulmonary Pressure Describes Lung Morphology During Decremental Positive End-Expiratory Pressure Trials in Obesity. Crit Care Med 2017 0.75
52 The minimal α-crystallin domain of Mj Hsp16.5 is functional at non-heat-shock conditions. Proteins 2013 0.75
53 Acyclic congeners from Actinoalloteichus cyanogriseus provide insights into cyclic bipyridine glycoside formation. Org Lett 2014 0.75
54 [Cloning, expression and characterization of the nucleotidylyltransferase gene-amiE in amicetin biosynthesis]. Wei Sheng Wu Xue Bao 2012 0.75