Published in Org Lett on June 13, 2012
Isolation, characterization, and bioactivity evaluation of 3-((6-methylpyrazin-2-yl)methyl)-1H-indole, a new alkaloid from a deep-sea-derived actinomycete Serinicoccus profundi sp. nov. Mar Drugs (2012) 0.84
Antibacterial and cytotoxic new napyradiomycins from the marine-derived Streptomyces sp. SCSIO 10428. Mar Drugs (2013) 0.84
Biological Activity of Recently Discovered Halogenated Marine Natural Products. Mar Drugs (2015) 0.84
Marine Indole Alkaloids. Mar Drugs (2015) 0.82
New spirotetronate antibiotics, lobophorins H and I, from a South China Sea-derived Streptomyces sp. 12A35. Mar Drugs (2013) 0.79
New natural products identified by combined genomics-metabolomics profiling of marine Streptomyces sp. MP131-18. Sci Rep (2017) 0.75
Crystal structure of rac-(3a'R,9a'R)-3a'-(indol-3-yl)-1',2',3',3a',4',9a'-hexa-hydro-spiro-[cyclo-pentane-1,9'-penta-leno[1,2-b]indole] p-xylene hemisolvate. Acta Crystallogr E Crystallogr Commun (2015) 0.75
Brevianamides and Mycophenolic Acid Derivatives from the Deep-Sea-Derived Fungus Penicillium brevicompactum DFFSCS025. Mar Drugs (2017) 0.75
Expansion of bisindole biosynthetic pathways by combinatorial construction. ACS Synth Biol (2015) 0.75
Deep Sea Actinomycetes and Their Secondary Metabolites. Front Microbiol (2017) 0.75
A large-scale analysis of mRNA polyadenylation of human and mouse genes. Nucleic Acids Res (2005) 7.24
High-throughput mapping of a dynamic signaling network in mammalian cells. Science (2005) 5.21
Inhibition of eukaryotic translation elongation by cycloheximide and lactimidomycin. Nat Chem Biol (2010) 3.44
Cytokines and their relationship to the symptoms and outcome of cancer. Nat Rev Cancer (2008) 2.89
A genome-wide association study identifies two new lung cancer susceptibility loci at 13q12.12 and 22q12.2 in Han Chinese. Nat Genet (2011) 2.85
CUL4A abrogation augments DNA damage response and protection against skin carcinogenesis. Mol Cell (2009) 2.79
Intravenous injection of methylprednisolone reduces the incidence of postextubation stridor in intensive care unit patients. Crit Care Med (2006) 2.75
Year in review in Intensive Care Medicine 2011: III. ARDS and ECMO, weaning, mechanical ventilation, noninvasive ventilation, pediatrics and miscellanea. Intensive Care Med (2012) 2.52
Outbreaks of Pneumocystis pneumonia in 2 renal transplant centers linked to a single strain of Pneumocystis: implications for transmission and virulence. Clin Infect Dis (2012) 2.51
Pulmonary coagulopathy as a new target in therapeutic studies of acute lung injury or pneumonia--a review. Crit Care Med (2006) 2.45
Expanding the promiscuity of a natural-product glycosyltransferase by directed evolution. Nat Chem Biol (2007) 2.31
Hepatic resection associated with good survival for selected patients with intermediate and advanced-stage hepatocellular carcinoma. Ann Surg (2014) 2.27
Antitumor antibiotics: bleomycin, enediynes, and mitomycin. Chem Rev (2005) 1.91
Sequence-based typing of Mycoplasma genitalium reveals sexual transmission. J Clin Microbiol (2006) 1.89
Optimizing glycosyltransferase specificity via "hot spot" saturation mutagenesis presents a catalyst for novobiocin glycorandomization. Chem Biol (2008) 1.84
Recombinant E. coli prototype strains for in vivo glycorandomization. ACS Chem Biol (2010) 1.82
Adiponectin deficiency promotes endothelial activation and profoundly exacerbates sepsis-related mortality. Am J Physiol Endocrinol Metab (2008) 1.79
Modulation of bacterial growth by tumor necrosis factor-alpha in vitro and in vivo. Am J Respir Crit Care Med (2003) 1.70
GABA exerts protective and regenerative effects on islet beta cells and reverses diabetes. Proc Natl Acad Sci U S A (2011) 1.69
Reconciling the "old" and "new" views of protein allostery: a molecular simulation study of chemotaxis Y protein (CheY). Proteins (2006) 1.67
The E3 ubiquitin ligase Cullin 4A regulates meiotic progression in mouse spermatogenesis. Dev Biol (2011) 1.67
Substrate elasticity provides mechanical signals for the expansion of hemopoietic stem and progenitor cells. Nat Biotechnol (2010) 1.66
Single-molecule fluorescence measurements of ribosomal translocation dynamics. Mol Cell (2011) 1.65
Differential gene profiling in acute lung injury identifies injury-specific gene expression. Crit Care Med (2008) 1.65
Effect of mechanical ventilation on cytokine response to intratracheal lipopolysaccharide. Anesthesiology (2004) 1.64
Mechanical stress induces lung fibrosis by epithelial-mesenchymal transition. Crit Care Med (2012) 1.63
Circadian rhythms: from basic mechanisms to the intensive care unit. Crit Care Med (2012) 1.63
Comparison of long-term survival of patients with BCLC stage B hepatocellular carcinoma after liver resection or transarterial chemoembolization. PLoS One (2013) 1.63
High-throughput synergy screening identifies microbial metabolites as combination agents for the treatment of fungal infections. Proc Natl Acad Sci U S A (2007) 1.62
Alternative polyadenylation of cyclooxygenase-2. Nucleic Acids Res (2005) 1.61
Clathrin and phosphatidylinositol-4,5-bisphosphate regulate autophagic lysosome reformation. Nat Cell Biol (2012) 1.60
Cytosporone B is an agonist for nuclear orphan receptor Nur77. Nat Chem Biol (2008) 1.58
XB130, a novel adaptor protein for signal transduction. J Biol Chem (2007) 1.56
Biosynthesis, purification, and substrate specificity of severe acute respiratory syndrome coronavirus 3C-like proteinase. J Biol Chem (2003) 1.54
Tolerance to acute isovolemic hemodilution. Effect of anesthetic depth. Anesthesiology (2003) 1.53
Coronary implantation using the autologous flap extension technique in complicated arterial switch operations. Pediatr Cardiol (2012) 1.52
Association analyses identify multiple new lung cancer susceptibility loci and their interactions with smoking in the Chinese population. Nat Genet (2012) 1.49
Induction of neuronal phenotypes from NG2+ glial progenitors by inhibiting epidermal growth factor receptor in mouse spinal cord injury. Glia (2012) 1.48
Exploring novel bioactive compounds from marine microbes. Curr Opin Microbiol (2005) 1.48
Biosynthesis of HSAF, a tetramic acid-containing macrolactam from Lysobacter enzymogenes. J Am Chem Soc (2010) 1.46
Comparative efficacy of postoperative transarterial chemoembolization with or without antiviral therapy for hepatitis B virus-related hepatocellular carcinoma. Tumour Biol (2015) 1.45
Hydrocarbon-degrading bacteria enriched by the Deepwater Horizon oil spill identified by cultivation and DNA-SIP. ISME J (2013) 1.44
Long non-coding RNA expression profile in human gastric cancer and its clinical significances. J Transl Med (2013) 1.43
Simultaneous quantification of metronidazole, tinidazole, ornidazole and morinidazole in human saliva. J Chromatogr B Analyt Technol Biomed Life Sci (2012) 1.43
Bioactive natural products from Lysobacter. Nat Prod Rep (2012) 1.42
Antibiotic optimization via in vitro glycorandomization. Nat Biotechnol (2003) 1.41
3D computerized segmentation of lung volume with computed tomography. Acad Radiol (2006) 1.41
Metabolic syndrome and all-cause mortality: a meta-analysis of prospective cohort studies. Eur J Epidemiol (2010) 1.40
Year in review in Intensive Care Medicine 2011. II. Cardiovascular, infections, pneumonia and sepsis, critical care organization and outcome, education, ultrasonography, metabolism and coagulation. Intensive Care Med (2012) 1.39
Inhibition of thrombin receptor signaling on α-smooth muscle actin(+) CD34(+) progenitors leads to repair after murine immune vascular injury. Arterioscler Thromb Vasc Biol (2011) 1.39
Mechanochemical coupling in the myosin motor domain. II. Analysis of critical residues. PLoS Comput Biol (2006) 1.39
The synthesis of SERS-active gold nanoflower tags for in vivo applications. ACS Nano (2008) 1.38
Designer enediynes generate DNA breaks, interstrand cross-links, or both, with concomitant changes in the regulation of DNA damage responses. Proc Natl Acad Sci U S A (2007) 1.38
Postsurgical comparison of pulsatile hemodynamics in five unique total cavopulmonary connections: identifying ideal connection strategies. Ann Thorac Surg (2013) 1.38
Pentacuspid aortic valve with severe aortic regurgitation. Ann Thorac Surg (2010) 1.38
A noncoding antisense RNA in tie-1 locus regulates tie-1 function in vivo. Blood (2009) 1.37
A phosphopantetheinylating polyketide synthase producing a linear polyene to initiate enediyne antitumor antibiotic biosynthesis. Proc Natl Acad Sci U S A (2008) 1.36
Temporal and spatial dissection of Shh signaling in genital tubercle development. Development (2009) 1.32
Systemic hypoxia and vasoconstrictor responsiveness in exercising human muscle. J Appl Physiol (1985) (2006) 1.31
Shape of tropoelastin, the highly extensible protein that controls human tissue elasticity. Proc Natl Acad Sci U S A (2011) 1.29
Acute phase response in zebrafish upon Aeromonas salmonicida and Staphylococcus aureus infection: striking similarities and obvious differences with mammals. Mol Immunol (2006) 1.29
Human neutrophil peptides induce interleukin-8 production through the P2Y6 signaling pathway. Blood (2005) 1.27
Neurally adjusted ventilatory assist decreases ventilator-induced lung injury and non-pulmonary organ dysfunction in rabbits with acute lung injury. Intensive Care Med (2009) 1.27
CUL-4A stimulates ubiquitylation and degradation of the HOXA9 homeodomain protein. EMBO J (2003) 1.27
Identification and characterization of the anti-methicillin-resistant Staphylococcus aureus WAP-8294A2 biosynthetic gene cluster from Lysobacter enzymogenes OH11. Antimicrob Agents Chemother (2011) 1.27
Substrate specificity of the macrolide-glycosylating enzyme pair DesVII/DesVIII: opportunities, limitations, and mechanistic hypotheses. Angew Chem Int Ed Engl (2006) 1.27
Impaired bone healing pattern in mice with ovariectomy-induced osteoporosis: A drill-hole defect model. Bone (2011) 1.26
The role of oxidative stress in adult critical care. Free Radic Biol Med (2005) 1.26
Identification of a subtelomeric gene family expressed during the asexual-sexual stage transition in Plasmodium falciparum. Mol Biochem Parasitol (2005) 1.24
An intronic polyadenylation site in human and mouse CstF-77 genes suggests an evolutionarily conserved regulatory mechanism. Gene (2005) 1.24
Production and assessment of decellularized pig and human lung scaffolds. Tissue Eng Part A (2013) 1.24
A Benchmark Study on Error Assessment and Quality Control of CCS Reads Derived from the PacBio RS. J Data Mining Genomics Proteomics (2013) 1.23
Tissue-specific requirements of beta-catenin in external genitalia development. Development (2008) 1.22
Mycoplasma genitalium-encoded MG309 activates NF-kappaB via Toll-like receptors 2 and 6 to elicit proinflammatory cytokine secretion from human genital epithelial cells. Infect Immun (2008) 1.22
Megastigmane and flavone glycosides from Acanthus ilicifolius. Pharmazie (2003) 1.21
Matrine induces apoptosis in human acute myeloid leukemia cells via the mitochondrial pathway and Akt inactivation. PLoS One (2012) 1.21
Xyloccensins O and P, unique 8,9,30-phragmalin ortho esters from Xylocarpus granatum. Org Lett (2004) 1.21
A distinct cellular profile is seen in the human endocervix during Chlamydia trachomatis infection. Am J Reprod Immunol (2008) 1.20
Gastric juice long noncoding RNA used as a tumor marker for screening gastric cancer. Cancer (2014) 1.20
Medicinal plants used by the Yi ethnic group: a case study in central Yunnan. J Ethnobiol Ethnomed (2009) 1.20
Acute respiratory distress syndrome: new definition, current and future therapeutic options. J Thorac Dis (2013) 1.19
Ultra-performance LC/TOF MS analysis of medicinal Panax herbs for metabolomic research. J Sep Sci (2008) 1.18
Metabolite profiling of Panax notoginseng using UPLC-ESI-MS. Phytochemistry (2008) 1.17
Investigation of volatile biomarkers in liver cancer blood using solid-phase microextraction and gas chromatography/mass spectrometry. Rapid Commun Mass Spectrom (2008) 1.16
The Wnt signaling pathway effector TCF7L2 controls gut and brain proglucagon gene expression and glucose homeostasis. Diabetes (2012) 1.16
Postoperative therapy options for hepatocellular carcinoma. Scand J Gastroenterol (2014) 1.15
Deciphering indolocarbazole and enediyne aminodideoxypentose biosynthesis through comparative genomics: insights from the AT2433 biosynthetic locus. Chem Biol (2006) 1.15
Workshop report on the extraction of foetal DNA from maternal plasma. Prenat Diagn (2007) 1.15
Biosynthesis of the beta-amino acid moiety of the enediyne antitumor antibiotic C-1027 featuring beta-amino acyl-S-carrier protein intermediates. J Am Chem Soc (2005) 1.14
Dynamics of translation by single ribosomes through mRNA secondary structures. Nat Struct Mol Biol (2013) 1.13
Retracted Secondary metabolites from endophytic Streptomyces aureofaciens CMUAc130 and their antifungal activity. Microbiology (2005) 1.13
Birth of parthenote mice directly from parthenogenetic embryonic stem cells. Stem Cells (2009) 1.13
T cell receptor-induced phosphoinositide-3-kinase p110delta activity is required for T cell localization to antigenic tissue in mice. J Clin Invest (2008) 1.13
Chlorogenic acid protects mice against lipopolysaccharide-induced acute lung injury. Injury (2010) 1.13
Genomic and secretomic analyses reveal unique features of the lignocellulolytic enzyme system of Penicillium decumbens. PLoS One (2013) 1.12
Essential role of the CUL4B ubiquitin ligase in extra-embryonic tissue development during mouse embryogenesis. Cell Res (2012) 1.12
Insulin-like growth factor 1 receptor enhances invasion and induces resistance to apoptosis of colon cancer cells through the Akt/Bcl-x(L) pathway. Cancer Res (2003) 1.12
Structure and mechanism of the rebeccamycin sugar 4'-O-methyltransferase RebM. J Biol Chem (2008) 1.12
Meta analysis of the association between MTHFR C677T polymorphism and the risk of congenital heart defects. Ann Hum Genet (2012) 1.12