Published in Adv Genet on January 01, 2010
The functional role of long non-coding RNA in human carcinomas. Mol Cancer (2011) 6.37
Cancer genetics and epigenetics: two sides of the same coin? Cancer Cell (2012) 3.65
Interplay between the cancer genome and epigenome. Cell (2013) 3.05
MicroRNAs in thyroid cancer. J Clin Endocrinol Metab (2011) 1.35
DNA methyltransferase controls stem cell aging by regulating BMI1 and EZH2 through microRNAs. PLoS One (2011) 1.27
A Novel YY1-miR-1 regulatory circuit in skeletal myogenesis revealed by genome-wide prediction of YY1-miRNA network. PLoS One (2012) 1.23
DNA methylation-regulated miR-193a-3p dictates resistance of hepatocellular carcinoma to 5-fluorouracil via repression of SRSF2 expression. J Biol Chem (2011) 1.19
miR-200c inhibits melanoma progression and drug resistance through down-regulation of BMI-1. Am J Pathol (2012) 1.13
Silencing of microRNA-122 enhances interferon-α signaling in the liver through regulating SOCS3 promoter methylation. Sci Rep (2012) 1.11
miR-29b induces SOCS-1 expression by promoter demethylation and negatively regulates migration of multiple myeloma and endothelial cells. Cell Cycle (2013) 1.06
MicroRNA-148b and microRNA-152 reactivate tumor suppressor genes through suppression of DNA methyltransferase-1 gene in pancreatic cancer cell lines. Cancer Biol Ther (2014) 1.04
MicroRNA expression and its implications for diagnosis and therapy of gallbladder cancer. Oncotarget (2015) 1.03
Interplay between Epigenetics and Genetics in Cancer. Genomics Inform (2013) 1.03
miR-200c inhibits invasion, migration and proliferation of bladder cancer cells through down-regulation of BMI-1 and E2F3. J Transl Med (2014) 1.01
Noncoding RNAs: new players in chronic pain. Anesthesiology (2014) 0.99
Microarray and deep sequencing cross-platform analysis of the mirRNome and isomiR variation in response to epidermal growth factor. BMC Genomics (2013) 0.97
miR-185 inhibits hepatocellular carcinoma growth by targeting the DNMT1/PTEN/Akt pathway. Am J Pathol (2014) 0.95
Modulation of miR-29 expression by α-fetoprotein is linked to the hepatocellular carcinoma epigenome. Hepatology (2014) 0.91
MiR-29a suppresses prostate cell proliferation and induces apoptosis via KDM5B protein regulation. Int J Clin Exp Med (2015) 0.87
Phospho-ΔNp63α/microRNA network modulates epigenetic regulatory enzymes in squamous cell carcinomas. Cell Cycle (2014) 0.87
Therapeutic Action of Fluoxetine is Associated with a Reduction in Prefrontal Cortical miR-1971 Expression Levels in a Mouse Model of Posttraumatic Stress Disorder. Front Psychiatry (2013) 0.87
The role of epigenetics in resistance to Cisplatin chemotherapy in lung cancer. Cancers (Basel) (2011) 0.86
Epigenetic regulation of miR-129-2 and its effects on the proliferation and invasion in lung cancer cells. J Cell Mol Med (2015) 0.86
Interpreting clinical assays for histone deacetylase inhibitors. Cancer Manag Res (2011) 0.85
Epigenetic therapy in lung cancer. Front Oncol (2013) 0.85
Alterations of DNA methylome in human bladder cancer. Epigenetics (2013) 0.85
MiR-21: an environmental driver of malignant melanoma? J Transl Med (2015) 0.82
Insights into the miRNA regulations in human disease genes. BMC Genomics (2014) 0.82
miRNAs and Other Epigenetic Changes as Biomarkers in Triple Negative Breast Cancer. Int J Mol Sci (2015) 0.80
Nanopharmacology in translational hematology and oncology. Int J Nanomedicine (2014) 0.80
Involvement of MicroRNA-210 Demethylation in Steroid-associated Osteonecrosis of the Femoral Head. Sci Rep (2016) 0.78
Reversal of microRNA-150 silencing disadvantages crizotinib-resistant NPM-ALK(+) cell growth. J Clin Invest (2015) 0.78
Epigenetic changes and nuclear factor-κB activation, but not microRNA-224, downregulate Raf-1 kinase inhibitor protein in triple-negative breast cancer SUM 159 cells. Oncol Lett (2015) 0.77
Mechanisms by Which Pleiotropic Amphiphilic n-3 PUFA Reduce Colon Cancer Risk. Curr Colorectal Cancer Rep (2014) 0.76
Epigenetics in Schistosomes: What We Know and What We Need Know. Front Cell Infect Microbiol (2016) 0.75
Comparison of blood RNA isolation methods from samples stabilized in Tempus tubes and stored at a large human biobank. BMC Res Notes (2016) 0.75
MiR-339 and especially miR-766 reactivate the expression of tumor suppressor genes in colorectal cancer cell lines through DNA methyltransferase 3B gene inhibition. Cancer Biol Ther (2016) 0.75
Down-regulated FSTL5 promotes cell proliferation and survival by affecting Wnt/β-catenin signaling in hepatocellular carcinoma. Int J Clin Exp Pathol (2015) 0.75
New Progress of Epigenetic Biomarkers in Urological Cancer. Dis Markers (2016) 0.75
Reciprocal regulation between microRNAs and epigenetic machinery in colorectal cancer. Oncol Lett (2017) 0.75
[Epigentics in rheumatic diseases]. Z Rheumatol (2011) 0.75
A microRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci U S A (2006) 40.09
MicroRNA gene expression deregulation in human breast cancer. Cancer Res (2005) 27.56
MicroRNA expression profiles associated with prognosis and therapeutic outcome in colon adenocarcinoma. JAMA (2008) 12.26
miRNAs, cancer, and stem cell division. Cell (2005) 12.15
MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B. Proc Natl Acad Sci U S A (2007) 9.82
MicroRNA signatures in human ovarian cancer. Cancer Res (2007) 9.45
MicroRNAs in Cancer. Annu Rev Med (2009) 9.37
The role of microRNA genes in papillary thyroid carcinoma. Proc Natl Acad Sci U S A (2005) 8.60
A microRNA signature of hypoxia. Mol Cell Biol (2006) 7.24
A microRNA DNA methylation signature for human cancer metastasis. Proc Natl Acad Sci U S A (2008) 7.14
MicroRNA expression and function in cancer. Trends Mol Med (2006) 7.02
Tcl1 expression in chronic lymphocytic leukemia is regulated by miR-29 and miR-181. Cancer Res (2006) 5.72
Relation between microRNA expression and progression and prognosis of gastric cancer: a microRNA expression analysis. Lancet Oncol (2009) 5.56
MicroRNAs--the micro steering wheel of tumour metastases. Nat Rev Cancer (2009) 5.47
MicroRNAs in body fluids--the mix of hormones and biomarkers. Nat Rev Clin Oncol (2011) 5.46
Cyclin G1 is a target of miR-122a, a microRNA frequently down-regulated in human hepatocellular carcinoma. Cancer Res (2007) 5.40
MicroRNA signatures associated with cytogenetics and prognosis in acute myeloid leukemia. Blood (2008) 5.23
Genomic profiling of microRNA and messenger RNA reveals deregulated microRNA expression in prostate cancer. Cancer Res (2008) 5.16
Human chronic lymphocytic leukemia modeled in mouse by targeted TCL1 expression. Proc Natl Acad Sci U S A (2002) 4.86
Micro-RNA profiling in kidney and bladder cancers. Urol Oncol (2007) 4.35
miR-328 functions as an RNA decoy to modulate hnRNP E2 regulation of mRNA translation in leukemic blasts. Cell (2010) 4.07
CD34+ hematopoietic stem-progenitor cell microRNA expression and function: a circuit diagram of differentiation control. Proc Natl Acad Sci U S A (2007) 4.06
Genetic and epigenetic silencing of microRNA-203 enhances ABL1 and BCR-ABL1 oncogene expression. Cancer Cell (2008) 4.01
Retracted A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function. Nat Genet (2009) 3.88
MicroRNA fingerprints during human megakaryocytopoiesis. Proc Natl Acad Sci U S A (2006) 3.80
RNA interference in the clinic: challenges and future directions. Nat Rev Cancer (2010) 3.43
MicroRNAs and other non-coding RNAs as targets for anticancer drug development. Nat Rev Drug Discov (2013) 3.33
MicroRNA 29b functions in acute myeloid leukemia. Blood (2009) 3.19
Association of a microRNA/TP53 feedback circuitry with pathogenesis and outcome of B-cell chronic lymphocytic leukemia. JAMA (2011) 3.16
Regulation of tumor angiogenesis by EZH2. Cancer Cell (2010) 3.10
Single-nucleotide polymorphisms inside microRNA target sites influence tumor susceptibility. Cancer Res (2010) 2.82
A genetic defect in exportin-5 traps precursor microRNAs in the nucleus of cancer cells. Cancer Cell (2010) 2.78
Reprogramming of miRNA networks in cancer and leukemia. Genome Res (2010) 2.65
Mammalian microRNAs: a small world for fine-tuning gene expression. Mamm Genome (2006) 2.64
Downregulation of microRNA expression in the lungs of rats exposed to cigarette smoke. FASEB J (2008) 2.58
CCAT2, a novel noncoding RNA mapping to 8q24, underlies metastatic progression and chromosomal instability in colon cancer. Genome Res (2013) 2.57
Concern Parkin, a gene implicated in autosomal recessive juvenile parkinsonism, is a candidate tumor suppressor gene on chromosome 6q25-q27. Proc Natl Acad Sci U S A (2003) 2.52
mRNA/microRNA gene expression profile in microsatellite unstable colorectal cancer. Mol Cancer (2007) 2.40
MicroRNAs. Cancer J (2008) 2.28
microRNA fingerprinting of CLL patients with chromosome 17p deletion identify a miR-21 score that stratifies early survival. Blood (2010) 2.25
Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing. Proc Natl Acad Sci U S A (2011) 2.21
Polymorphisms in microRNA targets: a gold mine for molecular epidemiology. Carcinogenesis (2008) 2.12
MicroRNAs and cancer: profile, profile, profile. Int J Cancer (2008) 2.10
SnapShot: MicroRNAs in Cancer. Cell (2009) 2.10
MicroRNA fingerprints identify miR-150 as a plasma prognostic marker in patients with sepsis. PLoS One (2009) 1.97
MicroRNAs and cancer--new paradigms in molecular oncology. Curr Opin Cell Biol (2009) 1.96
MicroRNA genes are frequently located near mouse cancer susceptibility loci. Proc Natl Acad Sci U S A (2007) 1.90
An integrated approach for experimental target identification of hypoxia-induced miR-210. J Biol Chem (2009) 1.90
Prognostic value of miR-155 in individuals with monoclonal B-cell lymphocytosis and patients with B chronic lymphocytic leukemia. Blood (2013) 1.87
Specific activation of microRNA106b enables the p73 apoptotic response in chronic lymphocytic leukemia by targeting the ubiquitin ligase Itch for degradation. Blood (2008) 1.87
Expression of microRNAs and protein-coding genes associated with perineural invasion in prostate cancer. Prostate (2008) 1.86
Alterations of the tumor suppressor gene ARLTS1 in ovarian cancer. Cancer Res (2006) 1.71
MicroRNA history: discovery, recent applications, and next frontiers. Mutat Res (2011) 1.66
MiR-15a and MiR-16 control Bmi-1 expression in ovarian cancer. Cancer Res (2009) 1.64
Regulatory mechanisms of microRNAs involvement in cancer. Expert Opin Biol Ther (2007) 1.57
Plasma microRNA 210 levels correlate with sensitivity to trastuzumab and tumor presence in breast cancer patients. Cancer (2011) 1.53
Regulation of microRNA expression: the hypoxic component. Cell Cycle (2007) 1.49
MicroRNA profiling in cancer. Clin Sci (Lond) (2011) 1.49
CCAT2, a novel long non-coding RNA in breast cancer: expression study and clinical correlations. Oncotarget (2013) 1.48
miR-124 inhibits STAT3 signaling to enhance T cell-mediated immune clearance of glioma. Cancer Res (2013) 1.46
MicroRNA involvement in brain tumors: from bench to bedside. Brain Pathol (2008) 1.40
MicroRNAome genome: a treasure for cancer diagnosis and therapy. CA Cancer J Clin (2014) 1.40
Strand-specific miR-28-5p and miR-28-3p have distinct effects in colorectal cancer cells. Gastroenterology (2012) 1.38
Identification of differentially expressed microRNAs by microarray: a possible role for microRNA genes in pituitary adenomas. J Cell Physiol (2007) 1.37
Retracted Unique microRNA profile in end-stage heart failure indicates alterations in specific cardiovascular signaling networks. J Biol Chem (2009) 1.33
Prooncogenic factors miR-23b and miR-27b are regulated by Her2/Neu, EGF, and TNF-α in breast cancer. Cancer Res (2013) 1.31
Relationships of microRNA expression in mouse lung with age and exposure to cigarette smoke and light. FASEB J (2009) 1.31
An miR-502-binding site single-nucleotide polymorphism in the 3'-untranslated region of the SET8 gene is associated with early age of breast cancer onset. Clin Cancer Res (2009) 1.30
Aberrant regulation of pVHL levels by microRNA promotes the HIF/VEGF axis in CLL B cells. Blood (2009) 1.29
Cell-to-cell miRNA transfer: from body homeostasis to therapy. Pharmacol Ther (2012) 1.27
Disrupted microRNA expression caused by Mecp2 loss in a mouse model of Rett syndrome. Epigenetics (2010) 1.26
Complex patterns of altered MicroRNA expression during the adenoma-adenocarcinoma sequence for microsatellite-stable colorectal cancer. Clin Cancer Res (2011) 1.25
Cancer-associated genomic regions (CAGRs) and noncoding RNAs: bioinformatics and therapeutic implications. Mamm Genome (2008) 1.23
Non-codingRNA sequence variations in human chronic lymphocytic leukemia and colorectal cancer. Carcinogenesis (2009) 1.23
MicroRNA down-regulated in human cholangiocarcinoma control cell cycle through multiple targets involved in the G1/S checkpoint. Hepatology (2011) 1.22
Frequent aberrant methylation of the CDH4 gene promoter in human colorectal and gastric cancer. Cancer Res (2004) 1.21
The Roles of MicroRNAs in the Cancer Invasion-Metastasis Cascade. Cancer Microenviron (2010) 1.21
UCbase & miRfunc: a database of ultraconserved sequences and microRNA function. Nucleic Acids Res (2008) 1.19
Adenoviral transduction of TESTIN gene into breast and uterine cancer cell lines promotes apoptosis and tumor reduction in vivo. Clin Cancer Res (2005) 1.18
MicroRNAs: fundamental facts and involvement in human diseases. Birth Defects Res C Embryo Today (2006) 1.17
Identification of a long non-coding RNA-associated RNP complex regulating metastasis at the translational step. EMBO J (2013) 1.14
Emerging roles of microRNAs in the molecular responses to hypoxia. Curr Pharm Des (2009) 1.14
Epigenetic silencing of microRNA-203 is required for EMT and cancer stem cell properties. Sci Rep (2013) 1.13
Chemoprevention of cigarette smoke-induced alterations of MicroRNA expression in rat lungs. Cancer Prev Res (Phila) (2010) 1.13
Expression, tissue distribution and function of miR-21 in esophageal squamous cell carcinoma. PLoS One (2013) 1.11
MicroRNAs in the ontogeny of leukemias and lymphomas. Leuk Lymphoma (2009) 1.11
Circulating microRNAs let-7a and miR-16 predict progression-free survival and overall survival in patients with myelodysplastic syndrome. Blood (2011) 1.09
Epigenetic regulation of miRNAs in cancer. Adv Exp Med Biol (2013) 1.09
Genetic polymorphisms in MicroRNA-related genes as predictors of clinical outcomes in colorectal adenocarcinoma patients. Clin Cancer Res (2012) 1.08
A novel non-coding RNA lncRNA-JADE connects DNA damage signalling to histone H4 acetylation. EMBO J (2013) 1.08
MicroRNA regulation of ionizing radiation-induced premature senescence. Int J Radiat Oncol Biol Phys (2010) 1.08
miRNAs and long noncoding RNAs as biomarkers in human diseases. Expert Rev Mol Diagn (2013) 1.08
Contact inhibition modulates intracellular levels of miR-223 in a p27kip1-dependent manner. Oncotarget (2014) 1.07
Cross talk between microRNA and coding cancer genes. Cancer J (2012) 1.06
MicroRNAs and ultraconserved genes as diagnostic markers and therapeutic targets in cancer and cardiovascular diseases. J Cardiovasc Transl Res (2010) 1.04
MicroRNAs miR-221 and miR-222: a new level of regulation in aggressive breast cancer. Genome Med (2011) 1.04
Signal transducer and activator of transcription (STAT)-3 regulates microRNA gene expression in chronic lymphocytic leukemia cells. Mol Cancer (2013) 1.04
Non-coding RNAs: identification of cancer-associated microRNAs by gene profiling. Technol Cancer Res Treat (2010) 1.03
MicroRNAs: a complex regulatory network drives the acquisition of malignant cell phenotype. Endocr Relat Cancer (2010) 1.03
Transcription signatures encoded by ultraconserved genomic regions in human prostate cancer. Mol Cancer (2013) 1.01