Published in Biol Psychiatry on December 01, 2010
Fear extinction as a model for translational neuroscience: ten years of progress. Annu Rev Psychol (2012) 4.04
Fear conditioning, synaptic plasticity and the amygdala: implications for posttraumatic stress disorder. Trends Neurosci (2011) 2.12
Neural and cellular mechanisms of fear and extinction memory formation. Neurosci Biobehav Rev (2012) 1.94
Seeking a spotless mind: extinction, deconsolidation, and erasure of fear memory. Neuron (2011) 1.80
Prefrontal dopamine and behavioral flexibility: shifting from an "inverted-U" toward a family of functions. Front Neurosci (2013) 1.18
The brain-specific microRNA miR-128b regulates the formation of fear-extinction memory. Nat Neurosci (2011) 1.13
Neural structures mediating expression and extinction of platform-mediated avoidance. J Neurosci (2014) 1.12
Single dose of L-dopa makes extinction memories context-independent and prevents the return of fear. Proc Natl Acad Sci U S A (2013) 1.05
Fear extinction induces mGluR5-mediated synaptic and intrinsic plasticity in infralimbic neurons. J Neurosci (2013) 1.01
Prefrontal cortical regulation of fear learning. Trends Neurosci (2014) 1.01
Failure of neural responses to safety cues in schizophrenia. Arch Gen Psychiatry (2012) 0.99
Human fear reconsolidation and allelic differences in serotonergic and dopaminergic genes. Transl Psychiatry (2012) 0.96
From the neurobiology of extinction to improved clinical treatments. Depress Anxiety (2013) 0.94
Bidirectional modulation of infralimbic dopamine D1 and D2 receptor activity regulates flexible reward seeking. Front Neurosci (2013) 0.93
Pharmacology of cognitive enhancers for exposure-based therapy of fear, anxiety and trauma-related disorders. Pharmacol Ther (2014) 0.92
Dopamine and extinction: a convergence of theory with fear and reward circuitry. Neurobiol Learn Mem (2013) 0.92
Going and stopping: dichotomies in behavioral control by the prefrontal cortex. Nat Neurosci (2016) 0.90
Empirical support for an involvement of the mesostriatal dopamine system in human fear extinction. Transl Psychiatry (2011) 0.87
Mechanisms to medicines: elucidating neural and molecular substrates of fear extinction to identify novel treatments for anxiety disorders. Br J Pharmacol (2014) 0.86
A unifying model of the role of the infralimbic cortex in extinction and habits. Learn Mem (2014) 0.83
Could dopamine agonists aid in drug development for anorexia nervosa? Front Nutr (2014) 0.82
Exercise Augmentation of Exposure Therapy for PTSD: Rationale and Pilot Efficacy Data. Cogn Behav Ther (2015) 0.82
Overexpression of Protein Kinase Mζ in the Prelimbic Cortex Enhances the Formation of Long-Term Fear Memory. Neuropsychopharmacology (2015) 0.81
Modulation of Fear Extinction by Stress, Stress Hormones and Estradiol: A Review. Front Behav Neurosci (2016) 0.79
Potent attenuation of context fear by extinction training contiguous with acquisition. Learn Mem (2014) 0.78
Highly differentiated cellular and circuit properties of infralimbic pyramidal neurons projecting to the periaqueductal gray and amygdala. Front Cell Neurosci (2015) 0.78
Escitalopram reversed the traumatic stress-induced depressed and anxiety-like symptoms but not the deficits of fear memory. Psychopharmacology (Berl) (2016) 0.77
Role of Dopamine 2 Receptor in Impaired Drug-Cue Extinction in Adolescent Rats. Cereb Cortex (2016) 0.76
Involvement of Dopamine D1/D5 and D2 Receptors in Context-Dependent Extinction Learning and Memory Reinstatement. Front Behav Neurosci (2016) 0.76
The DA antagonist tiapride impairs context-related extinction learning in a novel context without affecting renewal. Front Behav Neurosci (2015) 0.76
Enhancing dopaminergic signaling and histone acetylation promotes long-term rescue of deficient fear extinction. Transl Psychiatry (2016) 0.75
Control Over Stress Accelerates Extinction of Drug Seeking Via Prefrontal Cortical Activation. Neurobiol Stress (2015) 0.75
Adolescent social defeat alters N-methyl-d-aspartic acid receptor expression and impairs fear learning in adulthood. Behav Brain Res (2016) 0.75
Prefrontal Dopaminergic Mechanisms of Extinction in Adolescence Compared to Adulthood in Rats. Front Behav Neurosci (2017) 0.75
Regulation of Fear Extinction in the Basolateral Amygdala by Dopamine D2 Receptors Accompanied by Altered GluR1, GluR1-Ser845 and NR2B Levels. Front Behav Neurosci (2017) 0.75
Aripiprazole Facilitates Extinction of Conditioned Fear in Adolescent Rats. Front Behav Neurosci (2017) 0.75
Neurons in medial prefrontal cortex signal memory for fear extinction. Nature (2002) 8.43
An Akt/beta-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior. Cell (2005) 5.60
The projections of the ventral tegmental area and adjacent regions: a combined fluorescent retrograde tracer and immunofluorescence study in the rat. Brain Res Bull (1983) 5.23
Stimulation of medial prefrontal cortex decreases the responsiveness of central amygdala output neurons. J Neurosci (2003) 4.91
The role of ventromedial prefrontal cortex in the recovery of extinguished fear. J Neurosci (2000) 4.79
New vistas on amygdala networks in conditioned fear. J Neurophysiol (2004) 4.44
Dopamine receptor binding predicts clinical and pharmacological potencies of antischizophrenic drugs. Science (1976) 4.07
Dopamine receptor signaling. J Recept Signal Transduct Res (2004) 3.47
Consolidation of fear extinction requires NMDA receptor-dependent bursting in the ventromedial prefrontal cortex. Neuron (2007) 3.32
Consolidation of fear extinction requires protein synthesis in the medial prefrontal cortex. J Neurosci (2004) 2.88
Antipsychotic drug doses and neuroleptic/dopamine receptors. Nature (1976) 2.85
Distinct functions of the two isoforms of dopamine D2 receptors. Nature (2000) 2.83
Activation of orbital and medial prefrontal cortex by methylphenidate in cocaine-addicted subjects but not in controls: relevance to addiction. J Neurosci (2005) 2.41
Multiple dopamine receptor subtypes in the medial prefrontal cortex of the rat regulate set-shifting. Neuropsychopharmacology (2006) 2.19
Brain mechanisms of fear extinction: historical perspectives on the contribution of prefrontal cortex. Biol Psychiatry (2006) 2.11
Selective D2 receptor actions on the functional circuitry of working memory. Science (2004) 2.08
A role for the prefrontal cortex in stress- and cocaine-induced reinstatement of cocaine seeking in rats. Psychopharmacology (Berl) (2002) 2.08
Electrical stimulation of medial prefrontal cortex reduces conditioned fear in a temporally specific manner. Behav Neurosci (2004) 2.06
A subpopulation of neurons in the medial prefrontal cortex encodes emotional learning with burst and frequency codes through a dopamine D4 receptor-dependent basolateral amygdala input. J Neurosci (2005) 2.02
Noradrenergic signaling in infralimbic cortex increases cell excitability and strengthens memory for fear extinction. J Neurosci (2008) 1.84
Fast spiking and regular spiking neural correlates of fear conditioning in the medial prefrontal cortex of the rat. Cereb Cortex (2001) 1.71
Extinction memory is impaired in schizophrenia. Biol Psychiatry (2008) 1.50
Improved short-term spatial memory but impaired reversal learning following the dopamine D(2) agonist bromocriptine in human volunteers. Psychopharmacology (Berl) (2001) 1.44
Postextinction infusion of a mitogen-activated protein kinase inhibitor into the medial prefrontal cortex impairs memory of the extinction of conditioned fear. Learn Mem (2004) 1.42
Systemic blockade of D2-like dopamine receptors facilitates extinction of conditioned fear in mice. Learn Mem (2005) 1.30
Inhibition of amygdaloid dopamine D2 receptors impairs emotional learning measured with fear-potentiated startle. Brain Res (2001) 1.20
Haloperidol-induced catalepsy is mediated by postsynaptic dopamine receptors. Nature (1980) 1.19
Cellular distribution of dopamine D1 and D2 receptors in rat medial prefrontal cortex. J Neurosci (1993) 1.12
A role for dopamine D2 receptors in reversal learning. Neuroscience (2009) 1.07
Dopamine D2 receptor occupancy predicts catalepsy and the suppression of conditioned avoidance response behavior in rats. Psychopharmacology (Berl) (2000) 1.05
Layer V neurons bear the majority of mRNAs encoding the five distinct dopamine receptor subtypes in the primate prefrontal cortex. Synapse (1998) 1.01
Time course of extracellular catecholamine and glutamate levels in the rat medial prefrontal cortex during and after extinction of conditioned fear. Synapse (2007) 0.99
Prefrontocortical dopamine loss in rats delays long-term extinction of contextual conditioned fear, and reduces social interaction without affecting short-term social interaction memory. Neuropsychopharmacology (2002) 0.98
Predicting how equipotent doses of chlorpromazine, haloperidol, sulpiride, raclopride and clozapine reduce locomotor activity in mice. Eur Neuropsychopharmacol (2000) 0.98
Prefrontal dopamine D4 receptors are involved in encoding fear extinction. Neuroreport (2006) 0.98
Blockade of dopamine activity in the nucleus accumbens impairs learning extinction of conditioned fear. Learn Mem (2010) 0.94
D1- and D2-receptor antagonists induce catalepsy via different efferent striatal pathways [corrected]. Neurosci Lett (1988) 0.81
Acute systemic blockade of D2 receptors does not accelerate the extinction of cocaine-associated place preference. Brain Res (2009) 0.80
Atropine acts in the ventral striatum to reduce raclopride-induced catalepsy. Eur J Pharmacol (2001) 0.80
Effects of raclopride on exploratory locomotor activity, treadmill locomotion, conditioned avoidance behaviour and catalepsy in rats: behavioural profile comparisons between raclopride, haloperidol and preclamol. Pharmacol Toxicol (1987) 0.79
Extending fear extinction beyond anxiety disorders. Biol Psychiatry (2009) 0.78
3[H]-Sulpiride labels mesolimbic non-dopaminergic sites that bind antidepressant drugs. Experientia (1985) 0.77
Neurons in medial prefrontal cortex signal memory for fear extinction. Nature (2002) 8.43
Neuronal signalling of fear memory. Nat Rev Neurosci (2004) 7.03
Recall of fear extinction in humans activates the ventromedial prefrontal cortex and hippocampus in concert. Biol Psychiatry (2007) 5.56
New vistas on amygdala networks in conditioned fear. J Neurophysiol (2004) 4.44
Fear extinction as a model for translational neuroscience: ten years of progress. Annu Rev Psychol (2012) 4.04
Dissociable roles of prelimbic and infralimbic cortices, ventral hippocampus, and basolateral amygdala in the expression and extinction of conditioned fear. Neuropsychopharmacology (2010) 3.96
Sustained conditioned responses in prelimbic prefrontal neurons are correlated with fear expression and extinction failure. J Neurosci (2009) 3.76
Extinction circuits for fear and addiction overlap in prefrontal cortex. Learn Mem (2009) 3.62
Microstimulation reveals opposing influences of prelimbic and infralimbic cortex on the expression of conditioned fear. Learn Mem (2006) 3.52
Consolidation of fear extinction requires NMDA receptor-dependent bursting in the ventromedial prefrontal cortex. Neuron (2007) 3.32
Fear extinction in rats: implications for human brain imaging and anxiety disorders. Biol Psychol (2006) 3.32
Prefrontal control of fear: more than just extinction. Curr Opin Neurobiol (2010) 3.10
Consolidation of fear extinction requires protein synthesis in the medial prefrontal cortex. J Neurosci (2004) 2.88
Activity in prelimbic cortex is necessary for the expression of learned, but not innate, fears. J Neurosci (2007) 2.82
A role for the human dorsal anterior cingulate cortex in fear expression. Biol Psychiatry (2007) 2.78
Fear conditioning and extinction differentially modify the intrinsic excitability of infralimbic neurons. J Neurosci (2008) 2.77
Induction of fear extinction with hippocampal-infralimbic BDNF. Science (2010) 2.27
Delayed recall of fear extinction in rats with lesions of ventral medial prefrontal cortex. Learn Mem (2004) 2.09
Gating of fear in prelimbic cortex by hippocampal and amygdala inputs. Neuron (2012) 2.06
Lesions of the basal amygdala block expression of conditioned fear but not extinction. J Neurosci (2005) 1.87
Noradrenergic signaling in infralimbic cortex increases cell excitability and strengthens memory for fear extinction. J Neurosci (2008) 1.84
Inactivation of the ventromedial prefrontal cortex reduces expression of conditioned fear and impairs subsequent recall of extinction. Eur J Neurosci (2006) 1.82
The brain-derived neurotrophic factor Val66Met polymorphism predicts response to exposure therapy in posttraumatic stress disorder. Biol Psychiatry (2013) 1.54
Deep brain stimulation of the ventral striatum enhances extinction of conditioned fear. Proc Natl Acad Sci U S A (2012) 1.33
Recalling safety: cooperative functions of the ventromedial prefrontal cortex and the hippocampus in extinction. CNS Spectr (2007) 1.20
Systemic propranolol acts centrally to reduce conditioned fear in rats without impairing extinction. Biol Psychiatry (2009) 1.19
Memory for fear extinction requires mGluR5-mediated activation of infralimbic neurons. Cereb Cortex (2010) 1.18
Pharmacological facilitation of fear extinction and the search for adjunct treatments for anxiety disorders--the case of yohimbine. Trends Pharmacol Sci (2009) 1.17
Resting amygdala and medial prefrontal metabolism predicts functional activation of the fear extinction circuit. Am J Psychiatry (2012) 1.09
A biologically realistic network model of acquisition and extinction of conditioned fear associations in lateral amygdala neurons. J Neurophysiol (2008) 1.03
A time-dependent role of midline thalamic nuclei in the retrieval of fear memory. Neuropharmacology (2011) 1.00
Prelimbic and infralimbic neurons signal distinct aspects of appetitive instrumental behavior. PLoS One (2013) 0.98
Deep brain stimulation of the ventral striatum increases BDNF in the fear extinction circuit. Front Behav Neurosci (2013) 0.98
The effects of yohimbine and amphetamine on fear expression and extinction in rats. Psychopharmacology (Berl) (2009) 0.92
Neuroscience: Editing out fear. Nature (2010) 0.85
Fear signaling in the prelimbic-amygdala circuit: a computational modeling and recording study. J Neurophysiol (2013) 0.83
Extending fear extinction beyond anxiety disorders. Biol Psychiatry (2009) 0.78
The effect of repeated exposure to ethanol on pre-existing fear memories in rats. Psychopharmacology (Berl) (2015) 0.77
Keeping the memories flowing. Nat Neurosci (2006) 0.75