Published in Mol Oncol on September 26, 2010
Small changes huge impact: the role of protein posttranslational modifications in cellular homeostasis and disease. J Amino Acids (2011) 1.12
The human phosphotyrosine signaling network: evolution and hotspots of hijacking in cancer. Genome Res (2011) 1.07
Electron transfer dissociation mass spectrometry in proteomics. Proteomics (2012) 0.97
Alterations of histone H1 phosphorylation during bladder carcinogenesis. J Proteome Res (2013) 0.90
Deciphering Phosphotyrosine-Dependent Signaling Networks in Cancer by SH2 Profiling. Genes Cancer (2012) 0.88
-Omics and cancer biomarkers: link to the biological truth or bear the consequences. Cancer Epidemiol Biomarkers Prev (2012) 0.85
Over 2300 Phosphorylated Peptide Identifications with Single-Shot Capillary Zone Electrophoresis-Tandem Mass Spectrometry in a 100 min Separation. Anal Chem (2015) 0.85
Ovarian cancer: can proteomics give new insights for therapy and diagnosis? Int J Mol Sci (2013) 0.84
Proteomics of ovarian cancer: functional insights and clinical applications. Cancer Metastasis Rev (2015) 0.84
Quantitative proteomics and phosphoproteomics on serial tumor biopsies from a sorafenib-treated HCC patient. Proc Natl Acad Sci U S A (2016) 0.83
Kinotypes: stable species- and individual-specific profiles of cellular kinase activity. BMC Genomics (2013) 0.83
Advances in the proteomic discovery of novel therapeutic targets in cancer. Drug Des Devel Ther (2013) 0.82
Analytical challenges translating mass spectrometry-based phosphoproteomics from discovery to clinical applications. Electrophoresis (2014) 0.81
Phosphoproteomics and lung cancer research. Int J Mol Sci (2012) 0.79
Whole proteome analysis of mouse lymph nodes in cutaneous anthrax. PLoS One (2014) 0.79
An engineered lantipeptide synthetase serves as a general leader peptide-dependent kinase. Chem Commun (Camb) (2012) 0.79
Dysregulation of splicing proteins in head and neck squamous cell carcinoma. Cancer Biol Ther (2016) 0.77
Phosphotyrosine profiling identifies ephrin receptor A2 as a potential therapeutic target in esophageal squamous-cell carcinoma. Proteomics (2015) 0.77
Recent advances in mass spectrometry-based proteomics of gastric cancer. World J Gastroenterol (2016) 0.77
Recent advances in enrichment and separation strategies for mass spectrometry-based phosphoproteomics. Electrophoresis (2014) 0.76
Global phosphoproteomic profiling reveals distinct signatures in B-cell non-Hodgkin lymphomas. Am J Pathol (2014) 0.76
Temporal Phosphoproteome Dynamics Induced by an ATP Synthase Inhibitor Citreoviridin. Mol Cell Proteomics (2015) 0.75
Quantitative analysis of global phosphorylation changes with high-resolution tandem mass spectrometry and stable isotopic labeling. Methods (2013) 0.75
Early diagnosis of bladder cancer through the detection of urinary tyrosine-phosphorylated proteins. Br J Cancer (2015) 0.75
Phosphoproteomic analysis of gossypol-induced apoptosis in ovarian cancer cell line, HOC1a. Biomed Res Int (2014) 0.75
A dual specificity kinase, DYRK1A, as a potential therapeutic target for head and neck squamous cell carcinoma. Sci Rep (2016) 0.75
The G Protein-Coupled Estrogen Receptor Agonist G-1 Inhibits Nuclear Estrogen Receptor Activity and Stimulates Novel Phosphoproteomic Signatures. Toxicol Sci (2016) 0.75
Chemical Proteomic Approaches Targeting Cancer Stem Cells: A Review of Current Literature. Cancer Genomics Proteomics (2017) 0.75
The crucial role of protein phosphorylation in cell signaling and its use as targeted therapy (Review). Int J Mol Med (2017) 0.75
The hallmarks of cancer. Cell (2000) 113.05
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med (2004) 71.08
The protein kinase complement of the human genome. Science (2002) 35.36
Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia. N Engl J Med (2001) 24.51
Transforming gene product of Rous sarcoma virus phosphorylates tyrosine. Proc Natl Acad Sci U S A (1980) 22.30
Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem J (2000) 22.23
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. Cell (2006) 20.92
ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. Science (2007) 20.11
Multiplexed protein quantitation in Saccharomyces cerevisiae using amine-reactive isobaric tagging reagents. Mol Cell Proteomics (2004) 19.05
Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer. Cell (2007) 17.98
Identification of a transformation-specific antigen induced by an avian sarcoma virus. Nature (1977) 16.32
Oncogenic kinase signalling. Nature (2001) 16.30
Epidermal growth factor receptor mutations in lung cancer. Nat Rev Cancer (2007) 14.84
Protein-tyrosine kinases. Annu Rev Biochem (1985) 14.83
Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells. Nat Med (1996) 13.49
Evidence that the transforming gene of avian sarcoma virus encodes a protein kinase associated with a phosphoprotein. Cell (1978) 11.17
The specificities of protein kinase inhibitors: an update. Biochem J (2003) 7.76
Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. Nat Biotechnol (2004) 7.69
Global analysis of protein phosphorylation in yeast. Nature (2005) 7.46
Abelson murine leukaemia virus protein is phosphorylated in vitro to form phosphotyrosine. Nature (1980) 6.76
Evidence that the phosphorylation of tyrosine is essential for cellular transformation by Rous sarcoma virus. Cell (1980) 6.76
A screen of the complete protein kinase gene family identifies diverse patterns of somatic mutations in human breast cancer. Nat Genet (2005) 6.70
A systematic approach to the analysis of protein phosphorylation. Nat Biotechnol (2001) 6.66
Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors. Nat Biotechnol (2007) 6.56
Highly selective enrichment of phosphorylated peptides from peptide mixtures using titanium dioxide microcolumns. Mol Cell Proteomics (2005) 6.34
Biology of gastrointestinal stromal tumors. J Clin Oncol (2004) 5.89
Colorectal cancer: mutations in a signalling pathway. Nature (2005) 5.42
Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. Mol Cell (2008) 5.38
Signaling networks assembled by oncogenic EGFR and c-Met. Proc Natl Acad Sci U S A (2008) 5.08
Purification of DNA complementary to nucleotide sequences required for neoplastic transformation of fibroblasts by avian sarcoma viruses. J Mol Biol (1976) 5.07
Multiple reaction monitoring for robust quantitative proteomic analysis of cellular signaling networks. Proc Natl Acad Sci U S A (2007) 4.80
Nucleotide sequences related to the transforming gene of avian sarcoma virus are present in DNA of uninfected vertebrates. Proc Natl Acad Sci U S A (1978) 4.47
ErbB receptors and signaling pathways in cancer. Curr Opin Cell Biol (2009) 4.40
Reverse phase protein microarrays which capture disease progression show activation of pro-survival pathways at the cancer invasion front. Oncogene (2001) 4.40
Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules. Mol Cell Proteomics (2005) 4.33
Use of reverse phase protein microarrays and reference standard development for molecular network analysis of metastatic ovarian carcinoma. Mol Cell Proteomics (2005) 4.18
Selective isolation at the femtomole level of phosphopeptides from proteolytic digests using 2D-NanoLC-ESI-MS/MS and titanium oxide precolumns. Anal Chem (2004) 4.06
Global proteomic profiling of phosphopeptides using electron transfer dissociation tandem mass spectrometry. Proc Natl Acad Sci U S A (2007) 4.01
Anti-tumor activity of GW572016: a dual tyrosine kinase inhibitor blocks EGF activation of EGFR/erbB2 and downstream Erk1/2 and AKT pathways. Oncogene (2002) 3.87
Multiplexed protein measurement: technologies and applications of protein and antibody arrays. Nat Rev Drug Discov (2006) 3.83
Targeting the cancer kinome through polypharmacology. Nat Rev Cancer (2010) 3.74
Quantitative analysis of EGFRvIII cellular signaling networks reveals a combinatorial therapeutic strategy for glioblastoma. Proc Natl Acad Sci U S A (2007) 3.63
B-RAF is a therapeutic target in melanoma. Oncogene (2004) 3.61
Chemical proteomic profiles of the BCR-ABL inhibitors imatinib, nilotinib, and dasatinib reveal novel kinase and nonkinase targets. Blood (2007) 3.59
A method to identify serine kinase substrates. Akt phosphorylates a novel adipocyte protein with a Rab GTPase-activating protein (GAP) domain. J Biol Chem (2002) 3.33
Enrichment analysis of phosphorylated proteins as a tool for probing the phosphoproteome. Nat Biotechnol (2001) 3.14
Antitumor activity of HKI-272, an orally active, irreversible inhibitor of the HER-2 tyrosine kinase. Cancer Res (2004) 3.13
Profiling of UV-induced ATM/ATR signaling pathways. Proc Natl Acad Sci U S A (2007) 3.12
Peptide chips for the quantitative evaluation of protein kinase activity. Nat Biotechnol (2002) 3.05
Phosphorylation dynamics during early differentiation of human embryonic stem cells. Cell Stem Cell (2009) 3.03
An efficient proteomics method to identify the cellular targets of protein kinase inhibitors. Proc Natl Acad Sci U S A (2003) 2.75
Immobilized gallium(III) affinity chromatography of phosphopeptides. Anal Chem (1999) 2.70
Activating alleles of JAK3 in acute megakaryoblastic leukemia. Cancer Cell (2006) 2.69
Isolation of phosphoproteins by immobilized metal (Fe3+) affinity chromatography. Anal Biochem (1986) 2.55
Functional proteomics identifies targets of phosphorylation by B-Raf signaling in melanoma. Mol Cell (2009) 2.50
Large-scale proteomics analysis of the human kinome. Mol Cell Proteomics (2009) 2.49
Global target profile of the kinase inhibitor bosutinib in primary chronic myeloid leukemia cells. Leukemia (2008) 2.44
Mislocalized activation of oncogenic RTKs switches downstream signaling outcomes. Mol Cell (2009) 2.39
Proteomic and genetic approaches identify Syk as an AML target. Cancer Cell (2009) 2.39
Somatic mutations of EGFR in colorectal cancers and glioblastomas. N Engl J Med (2004) 2.33
Phosphoproteomic analysis of Her2/neu signaling and inhibition. Proc Natl Acad Sci U S A (2006) 2.30
Multiple reaction monitoring to identify sites of protein phosphorylation with high sensitivity. Mol Cell Proteomics (2005) 2.26
Identification of differentially expressed proteins in ovarian cancer using high-density protein microarrays. Proc Natl Acad Sci U S A (2007) 2.22
Phosphoproteomic analysis of human embryonic stem cells. Cell Stem Cell (2009) 2.19
Dissection of the insulin signaling pathway via quantitative phosphoproteomics. Proc Natl Acad Sci U S A (2008) 2.11
Quantitative proteomics using stable isotope labeling with amino acids in cell culture. Nat Protoc (2008) 2.07
Human embryonic stem cell phosphoproteome revealed by electron transfer dissociation tandem mass spectrometry. Proc Natl Acad Sci U S A (2009) 1.95
Global impact of oncogenic Src on a phosphotyrosine proteome. J Proteome Res (2008) 1.94
Evidence that the Abelson virus protein functions in vivo as a protein kinase that phosphorylates tyrosine. Proc Natl Acad Sci U S A (1981) 1.94
Cell-specific information processing in segregating populations of Eph receptor ephrin-expressing cells. Science (2009) 1.91
The selective tyrosine kinase inhibitor STI571 inhibits small cell lung cancer growth. Clin Cancer Res (2000) 1.88
Hydrophilic interaction chromatography reduces the complexity of the phosphoproteome and improves global phosphopeptide isolation and detection. Mol Cell Proteomics (2008) 1.88
Characterization of phosphoproteins from electrophoretic gels by nanoscale Fe(III) affinity chromatography with off-line mass spectrometry analysis. Proteomics (2001) 1.83
Selective detection and sequencing of phosphopeptides at the femtomole level by mass spectrometry. Anal Biochem (1996) 1.78
A mass spectrometry-based proteomic approach for identification of serine/threonine-phosphorylated proteins by enrichment with phospho-specific antibodies: identification of a novel protein, Frigg, as a protein kinase A substrate. Mol Cell Proteomics (2002) 1.78
Phosphoproteomic analysis of AML cell lines identifies leukemic oncogenes. Leuk Res (2006) 1.76
Global effects of kinase inhibitors on signaling networks revealed by quantitative phosphoproteomics. Mol Cell Proteomics (2009) 1.75
Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry. Anal Chem (2004) 1.72
Solid tumor proteome and phosphoproteome analysis by high resolution mass spectrometry. J Proteome Res (2008) 1.68
Profiling of tyrosine phosphorylation pathways in human cells using mass spectrometry. Proc Natl Acad Sci U S A (2003) 1.68
Stable isotope labeling with amino acids in cell culture (SILAC) for studying dynamics of protein abundance and posttranslational modifications. Sci STKE (2005) 1.67
Comparisons of tyrosine phosphorylated proteins in cells expressing lung cancer-specific alleles of EGFR and KRAS. Proc Natl Acad Sci U S A (2008) 1.51
Proteome, phosphoproteome, and N-glycoproteome are quantitatively preserved in formalin-fixed paraffin-embedded tissue and analyzable by high-resolution mass spectrometry. J Proteome Res (2010) 1.47
Signal pathway profiling of ovarian cancer from human tissue specimens using reverse-phase protein microarrays. Proteomics (2003) 1.40
An approach to locate phosphorylation sites in a phosphoprotein: mass mapping by combining specific enzymatic degradation with matrix-assisted laser desorption/ionization mass spectrometry. Anal Biochem (1994) 1.38
The glycolytic inhibitor 2-deoxyglucose activates multiple prosurvival pathways through IGF1R. J Biol Chem (2009) 1.30
Phosphoproteome analysis of HeLa cells using stable isotope labeling with amino acids in cell culture (SILAC). J Proteome Res (2005) 1.29
LKB1 is necessary for Akt-mediated phosphorylation of proapoptotic proteins. Cancer Res (2008) 1.28
A new approach for quantitative phosphoproteomic dissection of signaling pathways applied to T cell receptor activation. Mol Cell Proteomics (2009) 1.25
Targeting prostate cancer based on signal transduction and cell cycle pathways. Cell Cycle (2008) 1.25
Quantitative phosphoproteomics reveals a cluster of tyrosine kinases that mediates SRC invasive activity in advanced colon carcinoma cells. Cancer Res (2009) 1.25
Kinome profiling for studying lipopolysaccharide signal transduction in human peripheral blood mononuclear cells. J Biol Chem (2004) 1.22
Sensitive multiplexed analysis of kinase activities and activity-based kinase identification. Nat Biotechnol (2009) 1.21
The viral tyrosine protein kinases. Curr Top Microbiol Immunol (1986) 1.18
Quantitative phosphotyrosine proteomics of EphB2 signaling by stable isotope labeling with amino acids in cell culture (SILAC). J Proteome Res (2006) 1.13
Phosphoproteomic analysis of human brain by calcium phosphate precipitation and mass spectrometry. J Proteome Res (2008) 1.13
Identification of tyrosine-phosphorylated proteins associated with metastasis and functional analysis of FER in human hepatocellular carcinoma cells. BMC Cancer (2009) 1.11
The JAK-STAT pathway: a therapeutic target in hematological malignancies. Curr Cancer Drug Targets (2006) 1.09
Cancer proteomics by quantitative shotgun proteomics. Mol Oncol (2007) 1.08
Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics. Mol Cell Proteomics (2002) 30.58
Human Protein Reference Database--2009 update. Nucleic Acids Res (2008) 21.25
ONCOMINE: a cancer microarray database and integrated data-mining platform. Neoplasia (2004) 17.08
The HUPO PSI's molecular interaction format--a community standard for the representation of protein interaction data. Nat Biotechnol (2004) 16.08
Development of human protein reference database as an initial platform for approaching systems biology in humans. Genome Res (2003) 14.79
Human protein reference database--2006 update. Nucleic Acids Res (2006) 12.16
Human protein reference database as a discovery resource for proteomics. Nucleic Acids Res (2004) 9.99
Large-scale meta-analysis of cancer microarray data identifies common transcriptional profiles of neoplastic transformation and progression. Proc Natl Acad Sci U S A (2004) 9.42
The BioPAX community standard for pathway data sharing. Nat Biotechnol (2010) 9.19
Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1. Cell (2011) 7.33
Analysis of the human protein interactome and comparison with yeast, worm and fly interaction datasets. Nat Genet (2006) 6.74
GCN5 acetyltransferase complex controls glucose metabolism through transcriptional repression of PGC-1alpha. Cell Metab (2006) 4.50
Human Proteinpedia enables sharing of human protein data. Nat Biotechnol (2008) 4.21
Global proteomic profiling of phosphopeptides using electron transfer dissociation tandem mass spectrometry. Proc Natl Acad Sci U S A (2007) 4.01
Probabilistic model of the human protein-protein interaction network. Nat Biotechnol (2005) 3.99
Analysis of protein phosphorylation using mass spectrometry: deciphering the phosphoproteome. Trends Biotechnol (2002) 3.85
A curated compendium of phosphorylation motifs. Nat Biotechnol (2007) 3.79
An evaluation of human protein-protein interaction data in the public domain. BMC Bioinformatics (2006) 3.33
Vesiclepedia: a compendium for extracellular vesicles with continuous community annotation. PLoS Biol (2012) 3.18
A compendium of potential biomarkers of pancreatic cancer. PLoS Med (2009) 3.00
A role for thymic stromal lymphopoietin in CD4(+) T cell development. J Exp Med (2004) 2.81
Biomarker discovery from pancreatic cancer secretome using a differential proteomic approach. Mol Cell Proteomics (2005) 2.66
NetPath: a public resource of curated signal transduction pathways. Genome Biol (2010) 2.62
Sequential phosphorylation of CCAAT enhancer-binding protein beta by MAPK and glycogen synthase kinase 3beta is required for adipogenesis. Proc Natl Acad Sci U S A (2005) 2.51
Human Protein Reference Database and Human Proteinpedia as discovery tools for systems biology. Methods Mol Biol (2009) 2.47
Insights into the role of histone H3 and histone H4 core modifiable residues in Saccharomyces cerevisiae. Mol Cell Biol (2005) 2.33
Phosphoproteomic analysis of Her2/neu signaling and inhibition. Proc Natl Acad Sci U S A (2006) 2.30
Human Proteinpedia: a unified discovery resource for proteomics research. Nucleic Acids Res (2008) 2.30
From biological databases to platforms for biomedical discovery. Trends Biotechnol (2003) 2.27
K63-specific deubiquitination by two JAMM/MPN+ complexes: BRISC-associated Brcc36 and proteasomal Poh1. EMBO J (2009) 2.17
BioBuilder as a database development and functional annotation platform for proteins. BMC Bioinformatics (2004) 2.13
Quantitative proteomics using stable isotope labeling with amino acids in cell culture. Nat Protoc (2008) 2.07
Protein pyrophosphorylation by inositol pyrophosphates is a posttranslational event. Proc Natl Acad Sci U S A (2007) 2.03
Significant conservation of synthetic lethal genetic interaction networks between distantly related eukaryotes. Proc Natl Acad Sci U S A (2008) 2.01
Hsp70 and CHIP selectively mediate ubiquitination and degradation of hypoxia-inducible factor (HIF)-1alpha but Not HIF-2alpha. J Biol Chem (2009) 1.97
Chemical rescue of a mutant enzyme in living cells. Science (2006) 1.95
Global impact of oncogenic Src on a phosphotyrosine proteome. J Proteome Res (2008) 1.94
Comprehensive proteomic analysis of human pancreatic juice. J Proteome Res (2004) 1.93
Dynamic interplay between O-linked N-acetylglucosaminylation and glycogen synthase kinase-3-dependent phosphorylation. Mol Cell Proteomics (2007) 1.92
Disruption of Plasmodium falciparum development by antibodies against a conserved mosquito midgut antigen. Proc Natl Acad Sci U S A (2007) 1.81
A mass spectrometry-based proteomic approach for identification of serine/threonine-phosphorylated proteins by enrichment with phospho-specific antibodies: identification of a novel protein, Frigg, as a protein kinase A substrate. Mol Cell Proteomics (2002) 1.78
Plasma Proteome Database as a resource for proteomics research. Proteomics (2005) 1.76
Right pulmonary artery-to-left atrium communication: report of 5 cases. Ann Thorac Surg (2005) 1.75
Stable isotope labeling with amino acids in cell culture (SILAC) for studying dynamics of protein abundance and posttranslational modifications. Sci STKE (2005) 1.67
Human Protein Reference Database and Human Proteinpedia as resources for phosphoproteome analysis. Mol Biosyst (2011) 1.62
A proteomic approach for identification of secreted proteins during the differentiation of 3T3-L1 preadipocytes to adipocytes. Mol Cell Proteomics (2002) 1.61
A proteomic approach for quantitation of phosphorylation using stable isotope labeling in cell culture. Anal Chem (2003) 1.60
Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression. Proc Natl Acad Sci U S A (2012) 1.60
Construction of human activity-based phosphorylation networks. Mol Syst Biol (2013) 1.59
Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry. Mol Cell Proteomics (2011) 1.58
Comprehensive comparison of collision induced dissociation and electron transfer dissociation. Anal Chem (2008) 1.58
Context-specific effects of fibulin-5 (DANCE/EVEC) on cell proliferation, motility, and invasion. Fibulin-5 is induced by transforming growth factor-beta and affects protein kinase cascades. J Biol Chem (2002) 1.58
Mutant proteins as cancer-specific biomarkers. Proc Natl Acad Sci U S A (2011) 1.56
Comparisons of tyrosine phosphorylated proteins in cells expressing lung cancer-specific alleles of EGFR and KRAS. Proc Natl Acad Sci U S A (2008) 1.51
Genome annotation of Anopheles gambiae using mass spectrometry-derived data. BMC Genomics (2005) 1.51
Proteogenomics. Proteomics (2011) 1.48
Genomewide mRNA profiling of esophageal squamous cell carcinoma for identification of cancer biomarkers. Cancer Biol Ther (2009) 1.45
Malaria parasite invasion of the mosquito salivary gland requires interaction between the Plasmodium TRAP and the Anopheles saglin proteins. PLoS Pathog (2009) 1.44
Systematic interactome mapping and genetic perturbation analysis of a C. elegans TGF-beta signaling network. Mol Cell (2004) 1.40
New markers of pancreatic cancer identified through differential gene expression analyses: claudin 18 and annexin A8. Am J Surg Pathol (2008) 1.39
Evaluation of several MS/MS search algorithms for analysis of spectra derived from electron transfer dissociation experiments. Anal Chem (2009) 1.38
Utility of bile duct brushings for the early detection of cholangiocarcinoma in patients with primary sclerosing cholangitis. J Clin Gastroenterol (2006) 1.38
Tyrosine phosphorylation mapping of the epidermal growth factor receptor signaling pathway. J Biol Chem (2001) 1.37
A comprehensive map of the human urinary proteome. J Proteome Res (2011) 1.34
Plasma Proteome Database as a resource for proteomics research: 2014 update. Nucleic Acids Res (2013) 1.34
Human protein reference database and human proteinpedia as discovery resources for molecular biotechnology. Mol Biotechnol (2011) 1.31
Phosphoproteome analysis of HeLa cells using stable isotope labeling with amino acids in cell culture (SILAC). J Proteome Res (2005) 1.29
Identification of miR-21 targets in breast cancer cells using a quantitative proteomic approach. Proteomics (2009) 1.28
A quantitative proteomic approach for identification of potential biomarkers in hepatocellular carcinoma. J Proteome Res (2008) 1.27
A proteomic analysis of human bile. Mol Cell Proteomics (2004) 1.20
Antitumor activity and molecular effects of the novel heat shock protein 90 inhibitor, IPI-504, in pancreatic cancer. Mol Cancer Ther (2008) 1.18
Cloning of MASK, a novel member of the mammalian germinal center kinase III subfamily, with apoptosis-inducing properties. J Biol Chem (2001) 1.17
Transcriptomic and proteomic profiling of KEAP1 disrupted and sulforaphane-treated human breast epithelial cells reveals common expression profiles. Breast Cancer Res Treat (2011) 1.15
Role of p38 in replication of Trypanosoma brucei kinetoplast DNA. Mol Cell Biol (2006) 1.15
A functional annotation of subproteomes in human plasma. Proteomics (2005) 1.15
A proteogenomic analysis of Anopheles gambiae using high-resolution Fourier transform mass spectrometry. Genome Res (2011) 1.14
The Axl receptor tyrosine kinase is an adverse prognostic factor and a therapeutic target in esophageal adenocarcinoma. Cancer Biol Ther (2010) 1.12
Tackling the phosphoproteome: tools and strategies. Curr Opin Chem Biol (2003) 1.12
Identifying targets of miR-143 using a SILAC-based proteomic approach. Mol Biosyst (2010) 1.12
Casein kinase 2 binds to the C terminus of Na+/H+ exchanger 3 (NHE3) and stimulates NHE3 basal activity by phosphorylating a separate site in NHE3. Mol Biol Cell (2008) 1.10
Identification of novel highly expressed genes in pancreatic ductal adenocarcinomas through a bioinformatics analysis of expressed sequence tags. Cancer Biol Ther (2004) 1.10
NetSlim: high-confidence curated signaling maps. Database (Oxford) (2011) 1.09
Identification of secreted proteins that mediate cell-cell interactions in an in vitro model of the lung cancer microenvironment. Cancer Res (2008) 1.09
Inhibition of adipocyte differentiation by resistin-like molecule alpha. Biochemical characterization of its oligomeric nature. J Biol Chem (2002) 1.08
Temporal profiling of the secretome during adipogenesis in humans. J Proteome Res (2010) 1.07
PathBuilder--open source software for annotating and developing pathway resources. Bioinformatics (2009) 1.07
t4 workshop report: Pathways of Toxicity. ALTEX (2013) 1.06
Identification of c-Src tyrosine kinase substrates using mass spectrometry and peptide microarrays. J Proteome Res (2008) 1.06
A proteomic analysis of salivary glands of female Anopheles gambiae mosquito. Proteomics (2005) 1.05
Assessment of resolution parameters for CID-based shotgun proteomic experiments on the LTQ-Orbitrap mass spectrometer. J Am Soc Mass Spectrom (2010) 1.05
A novel proteomic approach for specific identification of tyrosine kinase substrates using [13C]tyrosine. J Biol Chem (2004) 1.05
Identification of c-Src tyrosine kinase substrates in platelet-derived growth factor receptor signaling. Mol Oncol (2009) 1.05
TSLP signaling network revealed by SILAC-based phosphoproteomics. Mol Cell Proteomics (2012) 1.04
Quantitative proteomics for identification of cancer biomarkers. Proteomics Clin Appl (2007) 1.04
O-linked N-acetylglucosamine modification on CCAAT enhancer-binding protein beta: role during adipocyte differentiation. J Biol Chem (2009) 1.04
Differentially expressed genes in pancreatic ductal adenocarcinomas identified through serial analysis of gene expression. Cancer Biol Ther (2004) 1.02
SILAC-based quantitative proteomic approach to identify potential biomarkers from the esophageal squamous cell carcinoma secretome. Cancer Biol Ther (2010) 1.00
LC-MS/MS analysis of differentially expressed glioblastoma membrane proteome reveals altered calcium signaling and other protein groups of regulatory functions. Mol Cell Proteomics (2012) 1.00
Copy-number variants in patients with a strong family history of pancreatic cancer. Cancer Biol Ther (2007) 0.99