| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: many differences, few similarities.
|
Diabetes
|
2005
|
5.54
|
|
2
|
T1DBase: integration and presentation of complex data for type 1 diabetes research.
|
Nucleic Acids Res
|
2006
|
3.25
|
|
3
|
Selective inhibition of eukaryotic translation initiation factor 2 alpha dephosphorylation potentiates fatty acid-induced endoplasmic reticulum stress and causes pancreatic beta-cell dysfunction and apoptosis.
|
J Biol Chem
|
2006
|
2.26
|
|
4
|
DNA methylation profiling identifies epigenetic dysregulation in pancreatic islets from type 2 diabetic patients.
|
EMBO J
|
2012
|
2.21
|
|
5
|
Non-invasive quantification of the beta cell mass by SPECT with ¹¹¹In-labelled exendin.
|
Diabetologia
|
2014
|
2.00
|
|
6
|
Detailed transcriptome atlas of the pancreatic beta cell.
|
BMC Med Genomics
|
2009
|
1.55
|
|
7
|
Restoration of the unfolded protein response in pancreatic β cells protects mice against type 1 diabetes.
|
Sci Transl Med
|
2013
|
1.55
|
|
8
|
Bcl-2 proteins in diabetes: mitochondrial pathways of β-cell death and dysfunction.
|
Trends Cell Biol
|
2011
|
1.54
|
|
9
|
Toll-like receptor 3 and STAT-1 contribute to double-stranded RNA+ interferon-gamma-induced apoptosis in primary pancreatic beta-cells.
|
J Biol Chem
|
2005
|
1.50
|
|
10
|
STAT1 is a master regulator of pancreatic {beta}-cell apoptosis and islet inflammation.
|
J Biol Chem
|
2010
|
1.49
|
|
11
|
Mild endoplasmic reticulum stress augments the proinflammatory effect of IL-1β in pancreatic rat β-cells via the IRE1α/XBP1s pathway.
|
Endocrinology
|
2012
|
1.49
|
|
12
|
T1DBase, a community web-based resource for type 1 diabetes research.
|
Nucleic Acids Res
|
2005
|
1.44
|
|
13
|
p53 up-regulated modulator of apoptosis (PUMA) activation contributes to pancreatic beta-cell apoptosis induced by proinflammatory cytokines and endoplasmic reticulum stress.
|
J Biol Chem
|
2010
|
1.39
|
|
14
|
Cytokines interleukin-1beta and tumor necrosis factor-alpha regulate different transcriptional and alternative splicing networks in primary beta-cells.
|
Diabetes
|
2009
|
1.39
|
|
15
|
Peripheral and islet interleukin-17 pathway activation characterizes human autoimmune diabetes and promotes cytokine-mediated β-cell death.
|
Diabetes
|
2011
|
1.33
|
|
16
|
PTPN2, a candidate gene for type 1 diabetes, modulates pancreatic β-cell apoptosis via regulation of the BH3-only protein Bim.
|
Diabetes
|
2011
|
1.26
|
|
17
|
MDA5 and PTPN2, two candidate genes for type 1 diabetes, modify pancreatic beta-cell responses to the viral by-product double-stranded RNA.
|
Hum Mol Genet
|
2010
|
1.25
|
|
18
|
Cytokines tumor necrosis factor-α and interferon-γ induce pancreatic β-cell apoptosis through STAT1-mediated Bim protein activation.
|
J Biol Chem
|
2011
|
1.20
|
|
19
|
GLIS3, a susceptibility gene for type 1 and type 2 diabetes, modulates pancreatic beta cell apoptosis via regulation of a splice variant of the BH3-only protein Bim.
|
PLoS Genet
|
2013
|
1.19
|
|
20
|
Double-stranded RNA induces pancreatic beta-cell apoptosis by activation of the toll-like receptor 3 and interferon regulatory factor 3 pathways.
|
Diabetes
|
2008
|
1.14
|
|
21
|
SUMO wrestling with type 1 diabetes.
|
J Mol Med (Berl)
|
2005
|
1.13
|
|
22
|
Loss of PPAR gamma in immune cells impairs the ability of abscisic acid to improve insulin sensitivity by suppressing monocyte chemoattractant protein-1 expression and macrophage infiltration into white adipose tissue.
|
J Nutr Biochem
|
2007
|
1.13
|
|
23
|
Proteomic analysis of SUMO4 substrates in HEK293 cells under serum starvation-induced stress.
|
Biochem Biophys Res Commun
|
2005
|
1.13
|
|
24
|
Type 2 diabetes mellitus--an autoimmune disease?
|
Nat Rev Endocrinol
|
2013
|
1.06
|
|
25
|
Transient oxidative stress damages mitochondrial machinery inducing persistent beta-cell dysfunction.
|
J Biol Chem
|
2009
|
1.04
|
|
26
|
The transcription factor C/EBP delta has anti-apoptotic and anti-inflammatory roles in pancreatic beta cells.
|
PLoS One
|
2012
|
1.03
|
|
27
|
Cell-permeable peptides induce dose- and length-dependent cytotoxic effects.
|
Biochim Biophys Acta
|
2007
|
1.00
|
|
28
|
Use of RNA interference to investigate cytokine signal transduction in pancreatic beta cells.
|
Methods Mol Biol
|
2012
|
0.98
|
|
29
|
1,25-Dihydroxyvitamin D3 curtails the inflammatory and T cell stimulatory capacity of macrophages through an IL-10-dependent mechanism.
|
Immunobiology
|
2012
|
0.98
|
|
30
|
Deletion of STAT-1 pancreatic islets protects against streptozotocin-induced diabetes and early graft failure but not against late rejection.
|
Diabetes
|
2007
|
0.96
|
|
31
|
The cytokine interleukin-1beta reduces the docking and fusion of insulin granules in pancreatic beta-cells, preferentially decreasing the first phase of exocytosis.
|
J Biol Chem
|
2004
|
0.96
|
|
32
|
JunB Inhibits ER Stress and Apoptosis in Pancreatic Beta Cells.
|
PLoS One
|
2008
|
0.96
|
|
33
|
Exposure to the viral by-product dsRNA or Coxsackievirus B5 triggers pancreatic beta cell apoptosis via a Bim / Mcl-1 imbalance.
|
PLoS Pathog
|
2011
|
0.96
|
|
34
|
Improvement of the mitochondrial antioxidant defense status prevents cytokine-induced nuclear factor-kappaB activation in insulin-producing cells.
|
Diabetes
|
2003
|
0.94
|
|
35
|
Gene microarray study corroborates proteomic findings in rodent islet cells.
|
J Proteome Res
|
2003
|
0.88
|
|
36
|
In silico identification of NF-kappaB-regulated genes in pancreatic beta-cells.
|
BMC Bioinformatics
|
2007
|
0.87
|
|
37
|
Construction and validation of the APOCHIP, a spotted oligo-microarray for the study of beta-cell apoptosis.
|
BMC Bioinformatics
|
2005
|
0.86
|
|
38
|
EuroDia: a beta-cell gene expression resource.
|
Database (Oxford)
|
2010
|
0.84
|
|
39
|
High-density oligonucleotide array analysis reveals extensive differences between freshly isolated blood and hepatic natural killer cells.
|
Eur J Immunol
|
2004
|
0.82
|
|
40
|
New approaches for in silico identification of cytokine-modified beta cell gene networks.
|
Ann N Y Acad Sci
|
2004
|
0.81
|
|
41
|
Macrophages enhance the radiosensitizing activity of lipid A: a novel role for immune cells in tumor cell radioresponse.
|
Int J Radiat Oncol Biol Phys
|
2004
|
0.79
|
|
42
|
Novel insights into the global proteome responses of insulin-producing INS-1E cells to different degrees of endoplasmic reticulum stress.
|
J Proteome Res
|
2010
|
0.79
|
|
43
|
Regulation and function of the cytosolic viral RNA sensor RIG-I in pancreatic beta cells.
|
Biochim Biophys Acta
|
2009
|
0.78
|
|
44
|
Identification of new pancreatic beta cell targets for in vivo imaging by a systems biology approach.
|
Curr Pharm Des
|
2010
|
0.77
|
|
45
|
Medical management of hyperglycemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy: a consensus statement of the American Diabetes Association and the European Association for the Study of Diabetes: response to Nathan et al.
|
Diabetes Care
|
2009
|
0.75
|
|
46
|
Erratum. Loss of Mbd2 Protects Mice Against High-Fat Diet-Induced Obesity and Insulin Resistance by Regulating the Homeostasis of Energy Storage and Expenditure Diabetes 2016;65:3384-3395.
|
Diabetes
|
2017
|
0.75
|