Published in Headache on October 14, 2010
Genes and primary headaches: discovering new potential therapeutic targets. J Headache Pain (2013) 0.80
A genome-wide analysis in cluster headache points to neprilysin and PACAP receptor gene variants. J Headache Pain (2016) 0.75
Dabigatran versus warfarin in patients with atrial fibrillation. N Engl J Med (2009) 39.97
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
Genome-wide association study identifies eight loci associated with blood pressure. Nat Genet (2009) 12.44
Risk factors for ischaemic and intracerebral haemorrhagic stroke in 22 countries (the INTERSTROKE study): a case-control study. Lancet (2010) 11.25
Apixaban in patients with atrial fibrillation. N Engl J Med (2011) 9.97
Stent-retriever thrombectomy after intravenous t-PA vs. t-PA alone in stroke. N Engl J Med (2015) 9.58
Meta-analysis and imputation refines the association of 15q25 with smoking quantity. Nat Genet (2010) 8.55
Vitamins E and C in the prevention of cardiovascular disease in men: the Physicians' Health Study II randomized controlled trial. JAMA (2008) 8.32
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet (2010) 7.94
Telmisartan to prevent recurrent stroke and cardiovascular events. N Engl J Med (2008) 7.25
Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer. Nat Genet (2008) 6.97
Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21. Nat Genet (2008) 6.75
Risk of bleeding with 2 doses of dabigatran compared with warfarin in older and younger patients with atrial fibrillation: an analysis of the randomized evaluation of long-term anticoagulant therapy (RE-LY) trial. Circulation (2011) 6.48
A mega-analysis of genome-wide association studies for major depressive disorder. Mol Psychiatry (2012) 6.34
A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium. Nat Genet (2009) 6.31
A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3. Nat Genet (2008) 6.26
Migraine and risk of cardiovascular disease in women. JAMA (2006) 6.16
Aspirin and extended-release dipyridamole versus clopidogrel for recurrent stroke. N Engl J Med (2008) 6.08
New loci associated with kidney function and chronic kidney disease. Nat Genet (2010) 5.58
Cryptogenic stroke and underlying atrial fibrillation. N Engl J Med (2014) 5.44
NXY-059 for acute ischemic stroke. N Engl J Med (2006) 5.32
Measures of obesity and cardiovascular risk among men and women. J Am Coll Cardiol (2008) 5.28
Vitamins E and C in the prevention of prostate and total cancer in men: the Physicians' Health Study II randomized controlled trial. JAMA (2008) 5.13
Migraine and cardiovascular disease: systematic review and meta-analysis. BMJ (2009) 4.98
Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations. PLoS Genet (2009) 4.97
GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Science (2013) 4.71
SLC2A9 influences uric acid concentrations with pronounced sex-specific effects. Nat Genet (2008) 4.67
Cost of disorders of the brain in Europe 2010. Eur Neuropsychopharmacol (2011) 4.63
Calcitonin gene-related peptide receptor antagonist BIBN 4096 BS for the acute treatment of migraine. N Engl J Med (2004) 4.39
Cohort profile: the study of health in Pomerania. Int J Epidemiol (2010) 4.38
OnabotulinumtoxinA for treatment of chronic migraine: pooled results from the double-blind, randomized, placebo-controlled phases of the PREEMPT clinical program. Headache (2010) 4.37
Benzodiazepine use and risk of dementia: prospective population based study. BMJ (2012) 4.32
Genome-wide association study identifies five loci associated with lung function. Nat Genet (2009) 4.10
Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways. Diabetes (2010) 4.07
Identification of common variants associated with human hippocampal and intracranial volumes. Nat Genet (2012) 3.73
Meta-analysis identifies six new susceptibility loci for atrial fibrillation. Nat Genet (2012) 3.71
NXY-059 for the treatment of acute ischemic stroke. N Engl J Med (2007) 3.70
Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels. Circulation (2011) 3.68
Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction. Nat Genet (2010) 3.55
Ximelagatran vs warfarin for stroke prevention in patients with nonvalvular atrial fibrillation: a randomized trial. JAMA (2005) 3.54
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet (2011) 3.40
Two new Loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and german study groups. PLoS Genet (2010) 3.21
Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. Nat Genet (2011) 3.18
Identification of genetic loci associated with Helicobacter pylori serologic status. JAMA (2013) 3.15
The predictive value of different measures of obesity for incident cardiovascular events and mortality. J Clin Endocrinol Metab (2010) 3.12
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. Nat Genet (2012) 3.04
Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. Nat Genet (2011) 3.03
Intracranial hemorrhage in atrial fibrillation patients during anticoagulation with warfarin or dabigatran: the RE-LY trial. Stroke (2012) 3.02
Gleason score and lethal prostate cancer: does 3 + 4 = 4 + 3? J Clin Oncol (2009) 2.94
Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. PLoS Genet (2013) 2.83
Rivaroxaban compared with warfarin in patients with atrial fibrillation and previous stroke or transient ischaemic attack: a subgroup analysis of ROCKET AF. Lancet Neurol (2012) 2.77
A prospective cohort study of cancer incidence following the diagnosis of Parkinson's disease. Cancer Epidemiol Biomarkers Prev (2007) 2.77
A genome-wide association scan identifies the hepatic cholesterol transporter ABCG8 as a susceptibility factor for human gallstone disease. Nat Genet (2007) 2.75
Frovatriptan for prophylactic treatment of cluster headache: lessons for future trial design. Headache (2010) 2.72
CUBN is a gene locus for albuminuria. J Am Soc Nephrol (2011) 2.70
2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS. Eur Heart J (2016) 2.70
Exceptional longevity in men: modifiable factors associated with survival and function to age 90 years. Arch Intern Med (2008) 2.67
Cardiovascular disease and subsequent kidney disease. Arch Intern Med (2007) 2.65
Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locus. Nature (2011) 2.59
Prospective study of Trichomonas vaginalis infection and prostate cancer incidence and mortality: Physicians' Health Study. J Natl Cancer Inst (2009) 2.50
Migraine and risk of cardiovascular disease in men. Arch Intern Med (2007) 2.49
Responsiveness of efficacy endpoints in clinical trials with over the counter analgesics for headache. Cephalalgia (2012) 2.46
Risks for stroke, bleeding, and death in patients with atrial fibrillation receiving dabigatran or warfarin in relation to the CHADS2 score: a subgroup analysis of the RE-LY trial. Ann Intern Med (2011) 2.45
Sex and the risk of restless legs syndrome in the general population. Arch Intern Med (2004) 2.43
Updated European Heart Rhythm Association Practical Guide on the use of non-vitamin K antagonist anticoagulants in patients with non-valvular atrial fibrillation. Europace (2015) 2.35
Inverse association between cancer and Alzheimer's disease: results from the Framingham Heart Study. BMJ (2012) 2.32
Association between body mass index and CKD in apparently healthy men. Am J Kidney Dis (2005) 2.30
Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension. PLoS Genet (2010) 2.24
Subclinical hyperthyroidism and the risk of coronary heart disease and mortality. Arch Intern Med (2012) 2.24
Migraine and mortality: a systematic review and meta-analysis. Cephalalgia (2011) 2.18
Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways. Nat Genet (2012) 2.12
Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data. JAMA (2009) 2.10
Migraine, migraine aura, and cervical artery dissection: a systematic review and meta-analysis. Cephalalgia (2011) 2.07
Migraine and obesity: epidemiology, mechanisms, and implications. Headache (2009) 2.05
Complications of endotracheal intubation in the critically ill. Intensive Care Med (2008) 2.04
Obesity and recurrent vascular risk after a recent ischemic stroke. Stroke (2011) 2.04
Glyburide and glimepiride pharmacokinetics in subjects with different CYP2C9 genotypes. Clin Pharmacol Ther (2002) 2.01
Incidence of cardiovascular disease and cancer in advanced age: prospective cohort study. BMJ (2008) 2.01
Apixaban compared with warfarin in patients with atrial fibrillation and previous stroke or transient ischaemic attack: a subgroup analysis of the ARISTOTLE trial. Lancet Neurol (2012) 1.99
CYP2D6 genotype and induction of intestinal drug transporters by rifampin predict presystemic clearance of carvedilol in healthy subjects. Clin Pharmacol Ther (2004) 1.99
Genome-wide association study reveals three susceptibility loci for common migraine in the general population. Nat Genet (2011) 1.98
Ultrasonographic hepatic steatosis increases prediction of mortality risk from elevated serum gamma-glutamyl transpeptidase levels. Hepatology (2009) 1.97
A prospective study of polyunsaturated fatty acid levels in blood and prostate cancer risk. Cancer Epidemiol Biomarkers Prev (2007) 1.94
Comment on "A common genetic variant is associated with adult and childhood obesity". Science (2007) 1.93