Cox Terhorst

Author PubWeight™ 121.70‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell 2005 24.00
2 Tight regulation of memory CD8(+) T cells limits their effectiveness during sustained high viral load. Immunity 2011 3.19
3 Homotypic interactions mediated by Slamf1 and Slamf6 receptors control NKT cell lineage development. Immunity 2007 3.02
4 Induction and role of regulatory CD4+CD25+ T cells in tolerance to the transgene product following hepatic in vivo gene transfer. Blood 2007 2.70
5 SAP couples Fyn to SLAM immune receptors. Nat Cell Biol 2003 2.27
6 The SAP and SLAM families in immune responses and X-linked lymphoproliferative disease. Nat Rev Immunol 2003 2.26
7 Inhibition of SHP2 ameliorates the pathogenesis of systemic lupus erythematosus. J Clin Invest 2016 2.06
8 Engineered AAV vector minimizes in vivo targeting of transduced hepatocytes by capsid-specific CD8+ T cells. Blood 2013 1.98
9 Signaling lymphocytic activation molecule-associated protein controls NKT cell functions. J Immunol 2005 1.98
10 Cutting edge: MyD88 controls phagocyte NADPH oxidase function and killing of gram-negative bacteria. J Immunol 2005 1.87
11 Cutting edge: the natural ligand for glucocorticoid-induced TNF receptor-related protein abrogates regulatory T cell suppression. J Immunol 2004 1.79
12 The SLAM and SAP gene families control innate and adaptive immune responses. Adv Immunol 2008 1.79
13 Colitis is associated with thymic destruction attenuating CD4+25+ regulatory T cells in the periphery. Gastroenterology 2004 1.78
14 The cell surface receptor SLAM controls T cell and macrophage functions. J Exp Med 2004 1.77
15 T cells as therapeutic targets in SLE. Nat Rev Rheumatol 2010 1.75
16 SLAM is a microbial sensor that regulates bacterial phagosome functions in macrophages. Nat Immunol 2010 1.68
17 The SLAM-associated protein signaling pathway is required for development of CD4+ T cells selected by homotypic thymocyte interaction. Immunity 2007 1.58
18 Role of tumor necrosis factor receptor 2 (TNFR2) in colonic epithelial hyperplasia and chronic intestinal inflammation in mice. Gastroenterology 2002 1.45
19 Improved induction of immune tolerance to factor IX by hepatic AAV-8 gene transfer. Hum Gene Ther 2009 1.36
20 Expansion of immunoglobulin-secreting cells and defects in B cell tolerance in Rag-dependent immunodeficiency. J Exp Med 2010 1.35
21 B cell-intrinsic deficiency of the Wiskott-Aldrich syndrome protein (WASp) causes severe abnormalities of the peripheral B-cell compartment in mice. Blood 2012 1.27
22 GITR engagement preferentially enhances proliferation of functionally competent CD4+CD25+FoxP3+ regulatory T cells. Int Immunol 2010 1.24
23 SLAM family receptors and the SLAM-associated protein (SAP) modulate T cell functions. Semin Immunopathol 2010 1.23
24 Induced reactivity of intestinal CD4(+) T cells with an epithelial cell lectin, galectin-4, contributes to exacerbation of intestinal inflammation. Immunity 2004 1.22
25 Molecular dissection of the signaling and costimulatory functions of CD150 (SLAM): CD150/SAP binding and CD150-mediated costimulation. Blood 2002 1.21
26 Cutting edge: the SLAM family receptor Ly108 controls T cell and neutrophil functions. J Immunol 2005 1.21
27 Defective B cell responses in the absence of SH2D1A. Proc Natl Acad Sci U S A 2005 1.21
28 Nonredundant roles of IL-10 and TGF-β in suppression of immune responses to hepatic AAV-factor IX gene transfer. Mol Ther 2011 1.18
29 Platelet aggregation induces platelet aggregate stability via SLAM family receptor signaling. Blood 2005 1.18
30 Tolerance induction to cytoplasmic beta-galactosidase by hepatic AAV gene transfer: implications for antigen presentation and immunotoxicity. PLoS One 2009 1.17
31 A "three-pronged" binding mechanism for the SAP/SH2D1A SH2 domain: structural basis and relevance to the XLP syndrome. EMBO J 2002 1.15
32 Circulatory antigen processing by mucosal dendritic cells controls CD8(+) T cell activation. Immunity 2012 1.15
33 Wiskott-Aldrich syndrome protein (WASP) and N-WASP are critical for peripheral B-cell development and function. Blood 2012 1.13
34 The role of SAP in murine CD150 (SLAM)-mediated T-cell proliferation and interferon gamma production. Blood 2002 1.10
35 Control freaks: immune regulatory cells. Nat Immunol 2004 1.08
36 A novel isoform of the Ly108 gene ameliorates murine lupus. J Exp Med 2011 1.07
37 Cutting edge: The adapters EAT-2A and -2B are positive regulators of CD244- and CD84-dependent NK cell functions in the C57BL/6 mouse. J Immunol 2010 1.07
38 Homozygous DNA ligase IV R278H mutation in mice leads to leaky SCID and represents a model for human LIG4 syndrome. Proc Natl Acad Sci U S A 2010 1.04
39 SAP increases FynT kinase activity and is required for phosphorylation of SLAM and Ly9. Int Immunol 2004 1.04
40 Increased expression of SLAM receptors SLAMF3 and SLAMF6 in systemic lupus erythematosus T lymphocytes promotes Th17 differentiation. J Immunol 2011 1.00
41 Increased proliferation of CD8+ T cells in SAP-deficient mice is associated with impaired activation-induced cell death. Eur J Immunol 2007 0.98
42 Dynamic redistribution of the activating 2B4/SAP complex at the cytotoxic NK cell immune synapse. J Immunol 2004 0.98
43 Mechanism of oral tolerance induction to therapeutic proteins. Adv Drug Deliv Rev 2012 0.96
44 Cutting edge: protein phosphatase 2A confers susceptibility to autoimmune disease through an IL-17-dependent mechanism. J Immunol 2012 0.95
45 Signaling lymphocyte activation molecule-associated protein is a negative regulator of the CD8 T cell response in mice. J Immunol 2005 0.95
46 SLAM/SLAM interactions inhibit CD40-induced production of inflammatory cytokines in monocyte-derived dendritic cells. Blood 2005 0.95
47 Role of the CD5 molecule on TCR gammadelta T cell-mediated immune functions: development of germinal centers and chronic intestinal inflammation. Int Immunol 2003 0.94
48 CD48 controls T-cell and antigen-presenting cell functions in experimental colitis. Gastroenterology 2006 0.93
49 Identification and characterization of SF2000 and SF2001, two new members of the immune receptor SLAM/CD2 family. Immunogenetics 2002 0.92
50 SAP expression in invariant NKT cells is required for cognate help to support B-cell responses. Blood 2012 0.92
51 Identification and characterization of two related murine genes, Eat2a and Eat2b, encoding single SH2-domain adapters. Immunogenetics 2006 0.92
52 Cutting edge: an NK cell-independent role for Slamf4 in controlling humoral autoimmunity. J Immunol 2011 0.91
53 Blocking CD27-CD70 costimulatory pathway suppresses experimental colitis. J Immunol 2009 0.91
54 The homolog of the five SH3-domain protein (HOFI/SH3PXD2B) regulates lamellipodia formation and cell spreading. PLoS One 2011 0.91
55 SLAMF6-driven co-stimulation of human peripheral T cells is defective in SLE T cells. Autoimmunity 2011 0.91
56 p40phox expression regulates neutrophil recruitment and function during the resolution phase of intestinal inflammation. J Immunol 2012 0.91
57 Rab5 activation by Toll-like receptor 2 is required for Trypanosoma cruzi internalization and replication in macrophages. Traffic 2008 0.90
58 Receptor signaling lymphocyte-activation molecule family 1 (Slamf1) regulates membrane fusion and NADPH oxidase 2 (NOX2) activity by recruiting a Beclin-1/Vps34/ultraviolet radiation resistance-associated gene (UVRAG) complex. J Biol Chem 2012 0.90
59 Cutting edge: Ly9 (CD229), a SLAM family receptor, negatively regulates the development of thymic innate memory-like CD8+ T and invariant NKT cells. J Immunol 2012 0.88
60 Cutting edge: Slamf8 is a negative regulator of Nox2 activity in macrophages. J Immunol 2012 0.88
61 Glucocorticoid-induced tumor necrosis factor receptor family-related protein regulates CD4(+)T cell-mediated colitis in mice. Gastroenterology 2011 0.88
62 I kappa B kinase 2 deficiency in T cells leads to defects in priming, B cell help, germinal center reactions, and homeostatic expansion. J Immunol 2004 0.88
63 T cell-specific expression of the murine CD3delta promoter. J Biol Chem 2002 0.88
64 Auto-antibody production and glomerulonephritis in congenic Slamf1-/- and Slamf2-/- [B6.129] but not in Slamf1-/- and Slamf2-/- [BALB/c.129] mice. Int Immunol 2011 0.87
65 Differential expression of CD150 (SLAM) family receptors by human hematopoietic stem and progenitor cells. Exp Hematol 2008 0.87
66 Blocking inducible co-stimulator in the absence of CD28 impairs Th1 and CD25+ regulatory T cells in murine colitis. Int Immunol 2004 0.86
67 Overlapping functions of human CD3delta and mouse CD3gamma in alphabeta T-cell development revealed in a humanized CD3gamma-mouse. Blood 2006 0.84
68 Signaling lymphocyte activation molecule regulates development of colitis in mice. Gastroenterology 2012 0.84
69 Mouse novel Ly9: a new member of the expanding CD150 (SLAM) family of leukocyte cell-surface receptors. Immunogenetics 2002 0.84
70 Expansion of an osteopontin-expressing T follicular helper cell subset correlates with autoimmunity in B6.Sle1b mice and is suppressed by the H1-isoform of the Slamf6 receptor. FASEB J 2013 0.84
71 Expression of the SH2D1A gene is regulated by a combination of transcriptional and post-transcriptional mechanisms. Eur J Immunol 2004 0.84
72 Glucocorticoid-induced TNF receptor family-related protein ligand regulates the migration of monocytes to the inflamed intestine. FASEB J 2013 0.84
73 Ly9 (CD229) Cell-Surface Receptor is Crucial for the Development of Spontaneous Autoantibody Production to Nuclear Antigens. Front Immunol 2013 0.84
74 The receptor Slamf1 on the surface of myeloid lineage cells controls susceptibility to infection by Trypanosoma cruzi. PLoS Pathog 2012 0.82
75 Mouse CD84 is a pan-leukocyte cell-surface molecule that modulates LPS-induced cytokine secretion by macrophages. J Leukoc Biol 2010 0.81
76 Mapping autoimmune disease genes in humans: lessons from IBD and SLE. Novartis Found Symp 2005 0.80
77 T cell CD3ζ deficiency enables multiorgan tissue inflammation. J Immunol 2013 0.80
78 CD3-T cell receptor co-stimulation through SLAMF3 and SLAMF6 receptors enhances RORγt recruitment to the IL17A promoter in human T lymphocytes. J Biol Chem 2012 0.80
79 A spectrum of mutations in SH2D1A that causes X-linked lymphoproliferative disease and other Epstein-Barr virus-associated illnesses. Leuk Lymphoma 2002 0.79
80 Phosphorylation of the N-terminal and C-terminal CD3-epsilon-ITAM tyrosines is differentially regulated in T cells. Biochem Biophys Res Commun 2002 0.77
81 SLAMF1 regulation of chemotaxis and autophagy determines CLL patient response. J Clin Invest 2015 0.77
82 Gene therapy research at the frontiers of viral immunology. Front Microbiol 2012 0.77
83 SAP modulates B cell functions in a genetic background-dependent manner. Immunol Lett 2013 0.77
84 The costimulatory molecule SLAM is critical for pulmonary allergic responses. Am J Respir Cell Mol Biol 2006 0.77
85 Recognition of Cluster of Differentiation 1 Antigens by Human CD4-CD8- CytolyticT Lymphocyte. Nature. 1989. 341: 447-450. 1989. J Immunol 2010 0.76
86 In vivo generation of oligoclonal colitic CD4+ T-cell lines expressing a distinct T-cell receptor Vbeta. Gastroenterology 2005 0.75
87 Editorial overview: Autoimmunity. Curr Opin Immunol 2014 0.75
88 Josiah F. Wedgwood (1950-2009). J Allergy Clin Immunol 2009 0.75