Microglia in close vicinity of glioma cells: correlation between phenotype and metabolic alterations.

PubWeight™: 0.86‹?›

🔗 View Article (PMC 2965014)

Published in Front Neuroenergetics on October 12, 2010

Authors

Pierre Voisin1, Véronique Bouchaud, Michel Merle, Philippe Diolez, Laura Duffy, Kristian Flint, Jean-Michel Franconi, Anne-Karine Bouzier-Sore

Author Affiliations

1: RMSB Center, Centre National de la Recherche Scientifique/Université Victor Segalen Bordeaux 2 Bordeaux, France.

Articles cited by this

Alternative activation of macrophages. Nat Rev Immunol (2003) 27.53

HIF-1alpha is essential for myeloid cell-mediated inflammation. Cell (2003) 9.12

Glutamate uptake into astrocytes stimulates aerobic glycolysis: a mechanism coupling neuronal activity to glucose utilization. Proc Natl Acad Sci U S A (1994) 6.96

Oxidative metabolism and PGC-1beta attenuate macrophage-mediated inflammation. Cell Metab (2006) 6.44

Uncoating ATPase is a member of the 70 kilodalton family of stress proteins. Cell (1986) 4.98

Immune function of microglia. Glia (2001) 4.59

Microglia as a source and target of cytokines. Glia (2002) 4.48

Mechanism of cellular 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction. J Neurochem (1997) 2.62

Rat macrophage lysosomal membrane antigen recognized by monoclonal antibody ED1. Immunology (1994) 2.32

Mitochondrial membrane potential and neuronal glutamate excitotoxicity: mortality and millivolts. Trends Neurosci (2000) 2.23

Microglia function in brain tumors. J Neurosci Res (2005) 2.18

A case for chaperones in antigen processing. Immunol Today (1992) 1.77

Control of apoptosis by the cellular ATP level. FEBS Lett (1996) 1.75

Human glioblastoma cells release interleukin 6 in vivo and in vitro. Cancer Res (1990) 1.70

Phagocytic activity of macrophages and microglial cells during the course of acute and chronic relapsing experimental autoimmune encephalomyelitis. J Neurosci Res (1994) 1.70

Not so Fas: Re-evaluating the mechanisms of immune privilege and tumor escape. Nat Med (2000) 1.67

Microglia in brain tumors. Glia (2002) 1.54

Microglia-derived TGF-beta as an important regulator of glioblastoma invasion--an inhibition of TGF-beta-dependent effects by shRNA against human TGF-beta type II receptor. Oncogene (2007) 1.40

Phospholipid metabolites as indicators of cancer cell function. NMR Biomed (1993) 1.36

Role of microglia in glioma biology. Microsc Res Tech (2001) 1.33

Characterization of microglia and macrophages in the central nervous system of rats: definition of the differential expression of molecules using standard and novel monoclonal antibodies in normal CNS and in four models of parenchymal reaction. Glia (1993) 1.32

Malignant glioma biology: role for TGF-beta in growth, motility, angiogenesis, and immune escape. Microsc Res Tech (2001) 1.30

Glucose and glutamine metabolism in C6 glioma cells studied by carbon 13 NMR. Biochimie (1996) 1.30

Macrophages in experimental and human brain tumors. Part 2: studies of the macrophage content of human brain tumors. J Neurosurg (1979) 1.27

Human microglial cells: characterization in cerebral tissue and in primary culture, and study of their susceptibility to HIV-1 infection. Ann Neurol (1991) 1.26

Quantitative assay by flow cytometry of the mitochondrial membrane potential in intact cells. Biochim Biophys Acta (1998) 1.19

Activation of murine microglial cell lines by lipopolysaccharide and interferon-gamma causes NO-mediated decreases in mitochondrial and cellular function. Eur J Neurosci (2001) 1.18

Phagocytosis of apoptotic inflammatory cells by microglia and modulation by different cytokines: mechanism for removal of apoptotic cells in the inflamed nervous system. Glia (2001) 1.17

10-N nonyl-acridine orange: a fluorescent probe which stains mitochondria independently of their energetic state. Biochem Biophys Res Commun (1989) 1.15

Early metabolic alterations in edematous perihematomal brain regions following experimental intracerebral hemorrhage. J Neurosurg (1998) 1.13

Cultured microglial cells have a distinct pattern of membrane channels different from peritoneal macrophages. J Neurosci Res (1990) 1.06

The impact of microglia-derived cytokines upon gliosis in the CNS. Dev Neurosci (1994) 1.05

Phosphorus-31 MR spectroscopy of normal adult human brain and brain tumours. NMR Biomed (2002) 1.04

Impaired capacity for upregulation of MHC class II in tumor-associated microglia. Glia (2005) 1.02

Proliferation-associated oxygen consumption and morphology of tumor cells in monolayer and spheroid culture. J Cell Physiol (1992) 1.00

Designer macrophages: oxidative metabolism fuels inflammation repair. Cell Metab (2006) 0.97

Class II transactivator and class II MHC gene expression in microglia: modulation by the cytokines TGF-beta, IL-4, IL-13 and IL-10. Eur J Immunol (1999) 0.96

Phagocytozing ameboid microglial cells studied in a mouse corpus callosum slice preparation. Glia (1996) 0.95

Dexamethasone-induced abolition of the inflammatory response in an experimental glioma model: a flow cytometry study. J Neurosurg (2000) 0.94

Continuous measurement of adenosine triphosphate with firefly luciferase luminescence. Methods Enzymol (1979) 0.93

31P nuclear magnetic resonance studies of phosphoglyceride metabolism in developing and degenerating brain: preliminary observations. J Neuropathol Exp Neurol (1987) 0.93

Immunotherapy for human glioma: innovative approaches and recent results. Expert Rev Anticancer Ther (2005) 0.91

The human astrocytoma cell line U373MG produces monocyte chemotactic protein (MCP)-1 upon stimulation with beta-amyloid protein. Neurosci Lett (2000) 0.88

Microglia only weakly present glioma antigen to cytotoxic T cells. Int J Dev Neurosci (1999) 0.88

Monokine modulation of human astroglial cell production of granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor. I. Effects of IL-1 alpha and IL-beta. J Immunol (1990) 0.88

Unique aspects of human newborn cerebral metabolism evaluated with phosphorus nuclear magnetic resonance spectroscopy. Ann Neurol (1984) 0.88

Glucose and lactate metabolism in C6 glioma cells: evidence for the preferential utilization of lactate for cell oxidative metabolism. Dev Neurosci (1998) 0.88

Monocyte chemoattractant protein-1 gene delivery enhances antitumor effects of herpes simplex virus thymidine kinase/ganciclovir system in a model of colon cancer. Cancer Gene Ther (2006) 0.87

Chromogranin A triggers a phenotypic transformation and the generation of nitric oxide in brain microglial cells. Neuroscience (1996) 0.87

Contribution of the phosphorylable complex I in the growth phase-dependent respiration of C6 glioma cells in vitro. J Bioenerg Biomembr (2003) 0.86

1H- and (31)P-MR spectroscopy of primary and recurrent human brain tumors in vitro: malignancy-characteristic profiles of water soluble and lipophilic spectral components. NMR Biomed (2001) 0.86

Phagocytosis of neuronal or glial debris by microglial cells: upregulation of MHC class II expression and multinuclear giant cell formation in vitro. Glia (2000) 0.86

Role of vasoactive intestinal peptide in inflammation and autoimmunity. Curr Opin Investig Drugs (2005) 0.85

HIV receptors within the brain: a study of CD4 and MHC-II on human neurons, astrocytes and microglial cells. Res Virol (1991) 0.85

Metabolic and cellular characterization of immortalized human microglial cells under heat stress. Neurochem Int (1998) 0.84

Energetic and morphological plasticity of C6 glioma cells grown on 3-D support; effect of transient glutamine deprivation. J Bioenerg Biomembr (1998) 0.84

Phosphorus-31 nuclear magnetic resonance of C6 glioma cells and rat astrocytes. Evidence for a modification of the longitudinal relaxation time of ATP and Pi during glucose starvation. Eur J Biochem (1991) 0.84

Response of glioma cells to interferon-gamma: increase in class II RNA, protein and mixed lymphocyte reaction-stimulating ability. Eur J Immunol (1985) 0.84

Characterization of lipids from human brain tissues by multinuclear magnetic resonance spectroscopy. Biopolymers (2001) 0.83

Compartmentation of lactate and glucose metabolism in C6 glioma cells. A 13c and 1H NMR study. J Biol Chem (1998) 0.83

Comparative 31P and 1H NMR studies on rat astrocytes and C6 glioma cells in culture. Biochimie (1993) 0.82

Mitochondrial impairment and recovery after heat shock treatment in a human microglial cell line. Neurochem Int (2000) 0.82

Increased neurons containing neuronal nitric oxide synthase in the brain of a hypoxic-ischemic neonatal rat model. Brain Dev (1997) 0.81

Fetal fuels II: contributions of selected carbon fuels to oxidative metabolism in rat conceptus. Am J Physiol (1977) 0.81

In situ flow cytometric analysis of nonyl acridine orange-stained mitochondria from splenocytes. Cytometry (1988) 0.81

Ki-M1P as a marker for microglia and brain macrophages in routinely processed human tissues. Acta Neuropathol (1992) 0.81

Phagocytic microglia release cytokines and cytotoxins that regulate the survival of astrocytes and neurons in culture. Neurochem Int (1994) 0.80

Induction of brain aquaporin 9 (AQP9) in catecholaminergic neurons in diabetic rats. Brain Res (2007) 0.80

Glioblastoma-associated circulating monocytes and the release of epidermal growth factor. J Neurosurg (1996) 0.80

Combined 1H-MR imaging and localized 31P-spectroscopy of intracranial tumors in 43 patients. J Comput Assist Tomogr (1988) 0.79

Depolymerization of macrophage microfilaments prevents induction and inhibits activity of nitric oxide synthase. Eur J Cell Biol (1996) 0.78

One-dimensional phosphorus-31 chemical shift imaging of human brain tumors. Invest Radiol (1995) 0.78

Macrophages and heat shock proteins. Res Immunol (1999) 0.78

Interrelationship among morphology, metabolism, and proliferation of tumor cells in monolayer and spheroid culture. Adv Exp Med Biol (1989) 0.77

Evaluation of mitochondrial content and activity with nonyl-acridine orange and rhodamine 123: flow cytometric analysis and comparison with quantitative morphometry. Comparative analysis by flow cytometry and quantitative morphometry of mitochondrial content and activity. Cytotechnology (1990) 0.77

31P and 13C nuclear magnetic resonance studies of macrophages. Immunomethods (1994) 0.76

Fluorescence automatic cell sorter and immunohistochemical investigation of CD68-positive cells in meningioma. Clin Neurol Neurosurg (1999) 0.76

Metabolic response of macrophages to injury promoted by the activated complement system. Cell Biochem Funct (1999) 0.76

Effects of phorbol myristate acetate (PMA) on functions of macrophages and microglia in vitro. Neurochem Res (1998) 0.76

Differential expression of heat shock 70 proteins in primary cultures from rat cerebellum. Brain Res (1996) 0.76

Articles by these authors

Activity-dependent regulation of energy metabolism by astrocytes: an update. Glia (2007) 3.35

S6 kinase deletion suppresses muscle growth adaptations to nutrient availability by activating AMP kinase. Cell Metab (2007) 1.92

Altered M1/M2 activation patterns of monocytes in severe relapsing experimental rat model of multiple sclerosis. Amelioration of clinical status by M2 activated monocyte administration. Mult Scler (2010) 1.84

Effects of exercise programs to prevent decline in health-related quality of life in highly deconditioned institutionalized elderly persons: a randomized controlled trial. Arch Intern Med (2010) 1.78

Glucose-induced remodeling of intermediary and energy metabolism in procyclic Trypanosoma brucei. J Biol Chem (2008) 1.26

Mitochondrial uncoupling protein 1 expressed in the heart of transgenic mice protects against ischemic-reperfusion damage. Circulation (2004) 1.21

Competition between glucose and lactate as oxidative energy substrates in both neurons and astrocytes: a comparative NMR study. Eur J Neurosci (2006) 1.17

ATP generation in the Trypanosoma brucei procyclic form: cytosolic substrate level is essential, but not oxidative phosphorylation. J Biol Chem (2003) 1.15

High harm avoidance and low self-directedness in euthymic young adults with recurrent, early-onset depression. J Affect Disord (2005) 1.13

Resistance to superinfection by a vigorously replicating, uncloned stock of simian immunodeficiency virus (SIVmac251) stimulates replication of a live attenuated virus vaccine (SIVmacC8). J Gen Virol (2008) 1.11

A mitochondrial NADH-dependent fumarate reductase involved in the production of succinate excreted by procyclic Trypanosoma brucei. J Biol Chem (2005) 1.09

Mitochondrial energetics is impaired in vivo in aged skeletal muscle. Aging Cell (2013) 1.06

Acetate produced in the mitochondrion is the essential precursor for lipid biosynthesis in procyclic trypanosomes. Proc Natl Acad Sci U S A (2009) 1.04

Close coupling between astrocytic and neuronal metabolisms to fulfill anaplerotic and energy needs in the rat brain. J Cereb Blood Flow Metab (2007) 1.03

Monitoring demyelination and remyelination by magnetization transfer imaging in the mouse brain at 9.4 T. MAGMA (2008) 1.02

Fumarate is an essential intermediary metabolite produced by the procyclic Trypanosoma brucei. J Biol Chem (2006) 0.99

High level of uncoupling protein 1 expression in muscle of transgenic mice selectively affects muscles at rest and decreases their IIb fiber content. J Biol Chem (2002) 0.97

Co-regulation of yeast purine and phosphate pathways in response to adenylic nucleotide variations. Mol Microbiol (2008) 0.96

Feeding active neurons: (re)emergence of a nursing role for astrocytes. J Physiol Paris (2002) 0.96

Use of lanthanide-grafted inorganic nanoparticles as effective contrast agents for cellular uptake imaging. Bioconjug Chem (2007) 0.95

Alteration of mitochondrial oxidative phosphorylation in aged skeletal muscle involves modification of adenine nucleotide translocator. Biochim Biophys Acta (2009) 0.94

Modular regulation analysis of heart contraction: application to in situ demonstration of a direct mitochondrial activation by calcium in beating heart. Am J Physiol Regul Integr Comp Physiol (2006) 0.94

3D TrueFISP imaging of mouse brain at 4.7T and 9.4T. J Magn Reson Imaging (2008) 0.93

Glucose and lactate metabolism in the awake and stimulated rat: a (13)C-NMR study. Front Neuroenergetics (2013) 0.92

Accurate determination of the oxidative phosphorylation affinity for ADP in isolated mitochondria. PLoS One (2011) 0.91

The threonine degradation pathway of the Trypanosoma brucei procyclic form: the main carbon source for lipid biosynthesis is under metabolic control. Mol Microbiol (2013) 0.90

Low affinity orthophosphate carriers regulate PHO gene expression independently of internal orthophosphate concentration in Saccharomyces cerevisiae. J Biol Chem (2004) 0.90

Fine tuning of the relaxometry of γ-Fe2O3@SiO2 nanoparticles by tweaking the silica coating thickness. ACS Nano (2010) 0.89

Ablation of succinate production from glucose metabolism in the procyclic trypanosomes induces metabolic switches to the glycerol 3-phosphate/dihydroxyacetone phosphate shuttle and to proline metabolism. J Biol Chem (2010) 0.88

Brain pyruvate recycling and peripheral metabolism: an NMR analysis ex vivo of acetate and glucose metabolism in the rat. J Neurochem (2007) 0.88

Identification of human scFvs targeting atherosclerotic lesions: selection by single round in vivo phage display. J Biol Chem (2006) 0.87

Ex vivo analysis of lactate and glucose metabolism in the rat brain under different states of depressed activity. J Biol Chem (2004) 0.87

ATP synthesis-coupled and -uncoupled acetate production from acetyl-CoA by mitochondrial acetate:succinate CoA-transferase and acetyl-CoA thioesterase in Trypanosoma. J Biol Chem (2012) 0.86

Absence of bone sialoprotein (BSP) impairs cortical defect repair in mouse long bone. Bone (2009) 0.86

Time-dependence of the contribution of pyruvate carboxylase versus pyruvate dehydrogenase to rat brain glutamine labelling from [1-(13) C]glucose metabolism. J Neurochem (2002) 0.86

Blood velocity assessment using 3D bright-blood time-resolved magnetic resonance angiography. Magn Reson Med (2006) 0.85

Improved energy supply regulation in chronic hypoxic mouse counteracts hypoxia-induced altered cardiac energetics. PLoS One (2010) 0.85

4D retrospective black blood trueFISP imaging of mouse heart. Magn Reson Med (2009) 0.85

Involvement of brain lactate in neuronal metabolism. NMR Biomed (2003) 0.84

The lateral supramalleolar flap: experience with 41 flaps. Ann Plast Surg (2005) 0.84

Parameter estimation in modeling phosphocreatine recovery in human skeletal muscle. Eur J Appl Physiol (2003) 0.83

In vivo modular control analysis of energy metabolism in contracting skeletal muscle. Biochem J (2008) 0.83

Surgical treatment of traumatic lesions of the axillary nerve. A retrospective study of 33 cases. Acta Orthop Belg (2004) 0.82

Intramuscular innervation of upper-limb skeletal muscles. Muscle Nerve (2004) 0.82

In vivo high-resolution 3D overhauser-enhanced MRI in mice at 0.2 T. Contrast Media Mol Imaging (2012) 0.82

In vivo phage display to identify new human antibody fragments homing to atherosclerotic endothelial and subendothelial tissues [corrected]. Am J Pathol (2012) 0.82

Ex vivo NMR study of lactate metabolism in rat brain under various depressed states. J Neurosci Res (2004) 0.82

MRI of inducible P-selectin expression in human activated platelets involved in the early stages of atherosclerosis. NMR Biomed (2010) 0.81

Short-term effect of erythropoietin on brain lesions and aquaporin-4 expression in a hypoxic-ischemic neonatal rat model assessed by magnetic resonance diffusion weighted imaging and immunohistochemistry. Pediatr Res (2010) 0.80

In vivo quantification of blood velocity in mouse carotid and pulmonary arteries by ECG-triggered 3D time-resolved magnetic resonance angiography. NMR Biomed (2009) 0.80

Cytosolic NADPH homeostasis in glucose-starved procyclic Trypanosoma brucei relies on malic enzyme and the pentose phosphate pathway fed by gluconeogenic flux. J Biol Chem (2013) 0.80

Fat grafting according to Coleman for the treatment of radial nerve neuromas. Plast Reconstr Surg (2010) 0.80

Inhibition of FGF receptor activity in glioma implanted into the mouse brain using the tetracyclin-regulated expression system. Angiogenesis (2004) 0.80

Heterologous protection elicited by candidate monomeric recombinant HIV-1 gp120 vaccine in the absence of cross neutralising antibodies in a macaque model. Retrovirology (2012) 0.79

In vivo MR tracking of therapeutic microglia to a human glioma model. NMR Biomed (2011) 0.79

In vivo MR angiography and velocity measurement in mice coronary arteries at 9.4 T: assessment of coronary flow velocity reserve. Radiology (2010) 0.79

Physiological heart activation by adrenaline involves parallel activation of ATP usage and supply. Biochem J (2008) 0.79

Xenografted human whole embryonic and fetal entoblastic organs develop and become functional adult-like micro-organs. J Surg Res (2002) 0.79

Inhibition of cardiac contractility by 5-hydroxydecanoate and tetraphenylphosphonium ion: a possible role of mitoKATP in response to inotropic stress. Am J Physiol Heart Circ Physiol (2006) 0.79

Long-term calorie restriction has minimal impact on brain metabolite and fatty acid profiles in aged rats on a Western-style diet. Neurochem Int (2013) 0.79

New concepts in molecular imaging: non-invasive MRI spotting of proteolysis using an Overhauser effect switch. PLoS One (2009) 0.78

Modular regulation analysis of integrative effects of hypoxia on the energetics of contracting skeletal muscle in vivo. Biochem J (2009) 0.78

Adjacent and spontaneous neurotization after distal digital replantation in children. Plast Reconstr Surg (2003) 0.78

Use of a free gracilis flap for coverage of medium size defects over the ankle and foot. Scand J Plast Reconstr Surg Hand Surg (2002) 0.78

Non-invasive integrative analysis of contraction energetics in intact beating heart. Int J Biochem Cell Biol (2012) 0.78

In vivo Overhauser-enhanced MRI of proteolytic activity. Contrast Media Mol Imaging (2014) 0.78

Production of magnetic multilamellar liposomes as highly T2-efficient MRI contrast agents. Nanomedicine (2010) 0.77

Modular control analysis of effects of chronic hypoxia on mouse heart. Am J Physiol Regul Integr Comp Physiol (2008) 0.77

Comprehensive phenotyping of salt-induced hypertensive heart disease in living mice using cardiac magnetic resonance. Eur Radiol (2012) 0.77

Adapted focal experimental autoimmune encephalomyelitis to allow MRI exploration of multiple sclerosis features. Exp Neurol (2011) 0.77

Application of MRI phase-difference mapping to assessment of vascular concentrations of BMS agent in mice. Contrast Media Mol Imaging (2008) 0.77

Alkoxyamines: a new family of pro-drugs against cancer. Concept for theranostics. Org Biomol Chem (2013) 0.77

Self-gated bSSFP sequences to detect iron-labeled cancer cells and/or metastases in vivo in mouse liver at 7 Tesla. J Magn Reson Imaging (2014) 0.77

Absence of mitochondrial activation during levosimendan inotropic action in perfused paced guinea pig hearts as demonstrated by modular control analysis. Am J Physiol Regul Integr Comp Physiol (2010) 0.76

Lymphedematous arm as donor site for radial forearm free flap in thoracic reconstruction. Plast Reconstr Surg (2010) 0.75