Reelin signals through apolipoprotein E receptor 2 and Cdc42 to increase growth cone motility and filopodia formation.

PubWeight™: 1.02‹?› | Rank: Top 15%

🔗 View Article (PMC 3523719)

Published in J Neurosci on November 03, 2010

Authors

Jost Leemhuis1, Elisabeth Bouché, Michael Frotscher, Frank Henle, Lutz Hein, Joachim Herz, Dieter K Meyer, Marina Pichler, Günter Roth, Carsten Schwan, Hans H Bock

Author Affiliations

1: Center for Neuroscience, Albert-Ludwigs-University, 79104 Freiburg, Germany.

Articles citing this

Nerve growth factor-induced formation of axonal filopodia and collateral branches involves the intra-axonal synthesis of regulators of the actin-nucleating Arp2/3 complex. J Neurosci (2012) 1.24

miR-124-regulated RhoG reduces neuronal process complexity via ELMO/Dock180/Rac1 and Cdc42 signalling. EMBO J (2012) 1.07

Reelin induces EphB activation. Cell Res (2013) 1.01

Mapping remodeling of thalamocortical projections in the living reeler mouse brain by diffusion tractography. Proc Natl Acad Sci U S A (2013) 0.89

Proteomic, genomic and translational approaches identify CRMP1 for a role in schizophrenia and its underlying traits. Hum Mol Genet (2012) 0.89

FE65 interacts with ADP-ribosylation factor 6 to promote neurite outgrowth. FASEB J (2013) 0.89

Lack of serotonin reuptake during brain development alters rostral raphe-prefrontal network formation. Front Cell Neurosci (2013) 0.88

Reelin-Disabled-1 signaling in neuronal migration: splicing takes the stage. Cell Mol Life Sci (2012) 0.83

Identification of CrkL-SH3 binding proteins from embryonic murine brain: implications for Reelin signaling during brain development. J Proteome Res (2011) 0.83

Reelin modulates cytoskeletal organization by regulating Rho GTPases. Commun Integr Biol (2011) 0.83

Role of the postnatal radial glial scaffold for the development of the dentate gyrus as revealed by Reelin signaling mutant mice. Glia (2013) 0.81

Characterization and distribution of Reelin-positive interneuron subtypes in the rat barrel cortex. Cereb Cortex (2013) 0.81

Contributions of VLDLR and LRP8 in the establishment of retinogeniculate projections. Neural Dev (2013) 0.79

miR-124-regulated RhoG: A conductor of neuronal process complexity. Small GTPases (2013) 0.79

Reelin immunoreactivity in neuritic varicosities in the human hippocampal formation of non-demented subjects and Alzheimer's disease patients. Acta Neuropathol Commun (2013) 0.79

Canonical and Non-canonical Reelin Signaling. Front Cell Neurosci (2016) 0.77

Reelin promotes microtubule dynamics in processes of developing neurons. Histochem Cell Biol (2012) 0.77

Neurotrophins regulate ApoER2 proteolysis through activation of the Trk signaling pathway. BMC Neurosci (2014) 0.76

Seizure-Induced Motility of Differentiated Dentate Granule Cells Is Prevented by the Central Reelin Fragment. Front Cell Neurosci (2016) 0.75

Functional Roles of the Interaction of APP and Lipoprotein Receptors. Front Mol Neurosci (2017) 0.75

Schizophrenia patient-derived olfactory neurosphere-derived cells do not respond to extracellular reelin. NPJ Schizophr (2016) 0.75

Optogenetic control of the Dab1 signaling pathway. Sci Rep (2017) 0.75

Correlates of Post-Stroke Brain Plasticity, Relationship to Pathophysiological Settings and Implications for Human Proof-of-Concept Studies. Front Cell Neurosci (2016) 0.75

Reelin: Neurodevelopmental Architect and Homeostatic Regulator of Excitatory Synapses. J Biol Chem (2016) 0.75

Articles cited by this

Rho GTPases: biochemistry and biology. Annu Rev Cell Dev Biol (2005) 16.77

Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation. J Biol Chem (1996) 10.08

Mammalian Rho GTPases: new insights into their functions from in vivo studies. Nat Rev Mol Cell Biol (2008) 8.99

Integrin-mediated activation of Cdc42 controls cell polarity in migrating astrocytes through PKCzeta. Cell (2001) 7.07

Rho GTPases and actin dynamics in membrane protrusions and vesicle trafficking. Trends Cell Biol (2006) 6.33

Reeler/Disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2. Cell (1999) 5.52

Rho GTPases and the control of cell behaviour. Biochem Soc Trans (2005) 5.38

Hippocampal neuronal polarity specified by spatially localized mPar3/mPar6 and PI 3-kinase activity. Cell (2003) 4.84

Activation of rac and cdc42 video imaged by fluorescent resonance energy transfer-based single-molecule probes in the membrane of living cells. Mol Cell Biol (2002) 4.50

The role of the Rho GTPases in neuronal development. Genes Dev (2005) 4.47

Schizophrenia as a disorder of neurodevelopment. Annu Rev Neurosci (2002) 4.36

Reelin and brain development. Nat Rev Neurosci (2003) 3.97

Trekking across the brain: the journey of neuronal migration. Cell (2007) 3.90

Direct binding of Reelin to VLDL receptor and ApoE receptor 2 induces tyrosine phosphorylation of disabled-1 and modulates tau phosphorylation. Neuron (1999) 3.70

Neuronal position in the developing brain is regulated by mouse disabled-1. Nature (1997) 3.60

Central nervous system neuronal migration. Annu Rev Neurosci (1999) 3.39

Signalling through Class I PI3Ks in mammalian cells. Biochem Soc Trans (2006) 3.37

Reelin is a ligand for lipoprotein receptors. Neuron (1999) 3.26

Phosphoinositide 3-kinase signalling pathways. J Cell Sci (2001) 3.24

Pituitary adenylate cyclase-activating polypeptide and its receptors: 20 years after the discovery. Pharmacol Rev (2009) 3.22

39-kDa protein modulates binding of ligands to low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor. J Biol Chem (1991) 3.17

Reelin, lipoprotein receptors and synaptic plasticity. Nat Rev Neurosci (2006) 2.95

The reeler gene-associated antigen on Cajal-Retzius neurons is a crucial molecule for laminar organization of cortical neurons. Neuron (1995) 2.82

Patterned delivery of immunoglobulins to surfaces using microfluidic networks. Science (1997) 2.79

Cytoskeletal coordination during neuronal migration. Proc Natl Acad Sci U S A (2005) 2.47

Reelin activates SRC family tyrosine kinases in neurons. Curr Biol (2003) 2.29

Fyn tyrosine kinase is a critical regulator of disabled-1 during brain development. Curr Biol (2003) 2.25

Essential roles for GSK-3s and GSK-3-primed substrates in neurotrophin-induced and hippocampal axon growth. Neuron (2006) 2.23

Defining mechanisms of actin polymerization and depolymerization during dendritic spine morphogenesis. J Cell Biol (2009) 2.21

Cullin 5 regulates Dab1 protein levels and neuron positioning during cortical development. Genes Dev (2007) 2.15

Polarized signaling endosomes coordinate BDNF-induced chemotaxis of cerebellar precursors. Neuron (2007) 2.13

Chemical inhibition of N-WASP by stabilization of a native autoinhibited conformation. Nat Struct Mol Biol (2004) 2.11

Neuronal polarity and trafficking. Neuron (2003) 2.10

Glycogen synthase kinase 3beta phosphorylation of microtubule-associated protein 1B regulates the stability of microtubules in growth cones. J Cell Sci (1999) 2.10

Mammalian Cdc42 is a brefeldin A-sensitive component of the Golgi apparatus. J Biol Chem (1996) 1.89

Reelin-mediated signaling locally regulates protein kinase B/Akt and glycogen synthase kinase 3beta. J Biol Chem (2002) 1.88

Secramine inhibits Cdc42-dependent functions in cells and Cdc42 activation in vitro. Nat Chem Biol (2005) 1.84

PAK promotes morphological changes by acting upstream of Rac. EMBO J (1998) 1.84

Phosphoinositide 3-kinase in disease: timing, location, and scaffolding. Curr Opin Cell Biol (2005) 1.83

The Reelin signaling pathway promotes dendritic spine development in hippocampal neurons. J Neurosci (2008) 1.75

Reelin glycoprotein: structure, biology and roles in health and disease. Mol Psychiatry (2005) 1.73

Actin dynamics at the Golgi complex in mammalian cells. Curr Opin Cell Biol (2006) 1.70

The cells of cajal-retzius: still a mystery one century after. Neuron (2005) 1.69

Activation of a Dab1/CrkL/C3G/Rap1 pathway in Reelin-stimulated neurons. Curr Biol (2004) 1.68

VPAC and PAC receptors: From ligands to function. Pharmacol Ther (2008) 1.65

Reelin modulates NMDA receptor activity in cortical neurons. J Neurosci (2005) 1.65

Neuronal polarity: vectorial cytoplasmic flow precedes axon formation. Neuron (1997) 1.62

Control of growth cone motility and morphology by LIM kinase and Slingshot via phosphorylation and dephosphorylation of cofilin. J Neurosci (2003) 1.58

A century of progress in corticoneurogenesis: from silver impregnation to genetic engineering. Cereb Cortex (2006) 1.58

Calcium signaling and the control of dendritic development. Neuron (2005) 1.58

Absence of Fyn and Src causes a reeler-like phenotype. J Neurosci (2005) 1.58

Massive loss of Cajal-Retzius cells does not disrupt neocortical layer order. Development (2006) 1.56

Interaction of reelin signaling and Lis1 in brain development. Nat Genet (2003) 1.56

Rho GTPases regulate axon growth through convergent and divergent signaling pathways. Neuron (2004) 1.55

A mechanism for inside-out lamination in the neocortex. Trends Neurosci (2008) 1.53

Reelin is a detachment signal in tangential chain-migration during postnatal neurogenesis. Nat Neurosci (2002) 1.52

Laminating the hippocampus. Nat Rev Neurosci (2006) 1.50

Regulation of protein tyrosine kinase signaling by substrate degradation during brain development. Mol Cell Biol (2003) 1.49

Divergent roles of ApoER2 and Vldlr in the migration of cortical neurons. Development (2007) 1.45

Reelin regulates postnatal neurogenesis and enhances spine hypertrophy and long-term potentiation. J Neurosci (2010) 1.45

Reelin stabilizes the actin cytoskeleton of neuronal processes by inducing n-cofilin phosphorylation at serine3. J Neurosci (2009) 1.44

Regulation of protein transport from the Golgi complex to the endoplasmic reticulum by CDC42 and N-WASP. Mol Biol Cell (2002) 1.42

Calcium-dependent interaction of Lis1 with IQGAP1 and Cdc42 promotes neuronal motility. Nat Neurosci (2005) 1.41

Reelin, Disabled 1, and beta 1 integrins are required for the formation of the radial glial scaffold in the hippocampus. Proc Natl Acad Sci U S A (2002) 1.41

Processing of Reelin by embryonic neurons is important for function in tissue but not in dissociated cultured neurons. J Neurosci (2007) 1.35

Molecular pathways regulating cytoskeletal organization and morphological changes in migrating neurons. Dev Neurosci (2008) 1.31

Apolipoprotein E receptors are required for reelin-induced proteasomal degradation of the neuronal adaptor protein Disabled-1. J Biol Chem (2004) 1.31

Modulation of lipoprotein receptor functions by intracellular adaptor proteins. Cell Signal (2006) 1.23

Signaling mechanisms that regulate actin-based motility processes in the nervous system. J Neurochem (2002) 1.22

Regulation of actin cytoskeleton by mDab1 through N-WASP and ubiquitination of mDab1. Biochem J (2004) 1.20

Analysis of the spatiotemporal activation of rho GTPases using Raichu probes. Methods Enzymol (2006) 1.18

Multiple actions of pituitary adenylyl cyclase activating peptide in nervous system development and regeneration. Dev Neurosci (2002) 1.12

Alzheimer's disease: neurodevelopment converges with neurodegeneration. Cell (2000) 1.05

Reelin regulates the development and synaptogenesis of the layer-specific entorhino-hippocampal connections. J Neurosci (1999) 1.04

An electron microscopic analysis of hippocampal neurons developing in culture: early stages in the emergence of polarity. J Neurosci (1993) 1.04

Involvement of the phosphatidylinositol 3-kinase/rac1 and cdc42 pathways in radial migration of cortical neurons. J Biol Chem (2004) 1.03

Reelin is a positional signal for the lamination of dentate granule cells. Development (2004) 1.01

Downregulation of functional Reelin receptors in projection neurons implies that primary Reelin action occurs at early/premigratory stages. J Neurosci (2009) 0.98

mPar6 alpha controls neuronal migration. J Neurosci (2006) 0.94

Mechanism of polarized protrusion formation on neuronal precursors migrating in the developing chicken cerebellum. J Cell Sci (2006) 0.93

Rho GTPases and phosphoinositide 3-kinase organize formation of branched dendrites. J Biol Chem (2003) 0.86

Vasoactive intestinal peptide and PACAP38 control N-methyl-D-aspartic acid-induced dendrite motility by modifying the activities of Rho GTPases and phosphatidylinositol 3-kinases. J Biol Chem (2006) 0.85

VIP induces the elongation of dendrites and axons in cultured hippocampal neurons: role of microtubules. Peptides (2007) 0.78

Pituitary adenylyl cyclase-activating polypeptide 38 reduces astroglial proliferation by inhibiting the GTPase RhoA. J Biol Chem (2005) 0.77

Articles by these authors

Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers. J Natl Cancer Inst (2005) 13.00

Suppression of aging in mice by the hormone Klotho. Science (2005) 8.11

Novel single chain cAMP sensors for receptor-induced signal propagation. J Biol Chem (2004) 5.00

Acquisition of the contractile phenotype by murine arterial smooth muscle cells depends on the Mir143/145 gene cluster. J Clin Invest (2009) 4.12

LRP: role in vascular wall integrity and protection from atherosclerosis. Science (2003) 3.89

Mutations and addiction to EGFR: the Achilles 'heal' of lung cancers? Trends Mol Med (2004) 3.44

Modulation of synaptic plasticity and memory by Reelin involves differential splicing of the lipoprotein receptor Apoer2. Neuron (2005) 3.25

Angiotensin-converting enzyme 2 protects from severe acute lung failure. Nature (2005) 3.09

Smooth muscle-selective deletion of guanylyl cyclase-A prevents the acute but not chronic effects of ANP on blood pressure. Proc Natl Acad Sci U S A (2002) 3.03

Fast synaptic inhibition promotes synchronized gamma oscillations in hippocampal interneuron networks. Proc Natl Acad Sci U S A (2002) 2.92

Microfluidic lab-on-a-chip platforms: requirements, characteristics and applications. Chem Soc Rev (2010) 2.79

Identification of neuronal RNA targets of TDP-43-containing ribonucleoprotein complexes. J Biol Chem (2010) 2.72

Reelin and ApoE receptors cooperate to enhance hippocampal synaptic plasticity and learning. J Biol Chem (2002) 2.67

Adult generation of glutamatergic olfactory bulb interneurons. Nat Neurosci (2009) 2.63

Lipoprotein receptors in the nervous system. Annu Rev Biochem (2001) 2.61

Amyloid precursor protein regulates brain apolipoprotein E and cholesterol metabolism through lipoprotein receptor LRP1. Neuron (2007) 2.55

Defining the actual sensitivity and specificity of the neurosphere assay in stem cell biology. Nat Methods (2006) 2.43

TDP-43 is a developmentally regulated protein essential for early embryonic development. J Biol Chem (2009) 2.40

Hippocampal plasticity requires postsynaptic ephrinBs. Nat Neurosci (2003) 2.37

Reelin activates SRC family tyrosine kinases in neurons. Curr Biol (2003) 2.29

Three-dimensional reconstruction of a calyx of Held and its postsynaptic principal neuron in the medial nucleus of the trapezoid body. J Neurosci (2002) 2.17

Feedback inhibition of catecholamine release by two different alpha2-adrenoceptor subtypes prevents progression of heart failure. Circulation (2002) 2.10

Apolipoprotein E and apolipoprotein E receptors: normal biology and roles in Alzheimer disease. Cold Spring Harb Perspect Med (2012) 2.01

Secretory COPII coat component Sec23a is essential for craniofacial chondrocyte maturation. Nat Genet (2006) 1.92

Suberoylanilide hydroxamic acid (vorinostat) up-regulates progranulin transcription: rational therapeutic approach to frontotemporal dementia. J Biol Chem (2011) 1.88

Reelin-mediated signaling locally regulates protein kinase B/Akt and glycogen synthase kinase 3beta. J Biol Chem (2002) 1.88

Nanodomain coupling between Ca2+ channels and Ca2+ sensors promotes fast and efficient transmitter release at a cortical GABAergic synapse. Neuron (2008) 1.86

Subcellular localization of metabotropic GABA(B) receptor subunits GABA(B1a/b) and GABA(B2) in the rat hippocampus. J Neurosci (2003) 1.85

Proteolytic processing of low density lipoprotein receptor-related protein mediates regulated release of its intracellular domain. J Biol Chem (2002) 1.83

Neuronal LRP1 functionally associates with postsynaptic proteins and is required for normal motor function in mice. Mol Cell Biol (2004) 1.81

Synaptopodin-deficient mice lack a spine apparatus and show deficits in synaptic plasticity. Proc Natl Acad Sci U S A (2003) 1.79

Inhibition of Na(+)-H(+) exchange prevents hypertrophy, fibrosis, and heart failure in beta(1)-adrenergic receptor transgenic mice. Circ Res (2002) 1.79

Direct evidence for a beta 1-adrenergic receptor-directed autoimmune attack as a cause of idiopathic dilated cardiomyopathy. J Clin Invest (2004) 1.77

Antiphospholipid antibodies promote leukocyte-endothelial cell adhesion and thrombosis in mice by antagonizing eNOS via β2GPI and apoER2. J Clin Invest (2010) 1.77

Platelet-derived growth factor mediates tyrosine phosphorylation of the cytoplasmic domain of the low Density lipoprotein receptor-related protein in caveolae. J Biol Chem (2002) 1.74

Impaired heart contractility in Apelin gene-deficient mice associated with aging and pressure overload. Circ Res (2007) 1.74

Adipocyte LDL receptor-related protein-1 expression modulates postprandial lipid transport and glucose homeostasis in mice. J Clin Invest (2007) 1.73

Lrp4, a novel receptor for Dickkopf 1 and sclerostin, is expressed by osteoblasts and regulates bone growth and turnover in vivo. PLoS One (2009) 1.67

Candidate pheromone receptors provide the basis for the response of distinct antennal neurons to pheromonal compounds. Eur J Neurosci (2007) 1.67

Receptor clustering is involved in Reelin signaling. Mol Cell Biol (2004) 1.66

Endocytic receptor LRP together with tPA and PAI-1 coordinates Mac-1-dependent macrophage migration. EMBO J (2006) 1.66

BDNF and its pro-peptide are stored in presynaptic dense core vesicles in brain neurons. J Cell Biol (2012) 1.65

Reelin modulates NMDA receptor activity in cortical neurons. J Neurosci (2005) 1.65

TDP-43 is directed to stress granules by sorbitol, a novel physiological osmotic and oxidative stressor. Mol Cell Biol (2010) 1.64

Neuronal migration in the murine rostral migratory stream requires serum response factor. Proc Natl Acad Sci U S A (2005) 1.64

Physiological significance of alpha(2)-adrenergic receptor subtype diversity: one receptor is not enough. Am J Physiol Regul Integr Comp Physiol (2002) 1.63

Phosphatidylinositol 3-kinase interacts with the adaptor protein Dab1 in response to Reelin signaling and is required for normal cortical lamination. J Biol Chem (2003) 1.63

Serum response factor controls neuronal circuit assembly in the hippocampus. Nat Neurosci (2006) 1.61

Lrp4 modulates extracellular integration of cell signaling pathways in development. PLoS One (2008) 1.60

Hippocampal synapses depend on hippocampal estrogen synthesis. J Neurosci (2004) 1.60

Ablation of mineralocorticoid receptors in myocytes but not in fibroblasts preserves cardiac function. Hypertension (2011) 1.59

Role of smooth muscle cGMP/cGKI signaling in murine vascular restenosis. Arterioscler Thromb Vasc Biol (2008) 1.58

ApoE4 reduces glutamate receptor function and synaptic plasticity by selectively impairing ApoE receptor recycling. Proc Natl Acad Sci U S A (2010) 1.57

Normal sorting but defective endocytosis of the low density lipoprotein receptor in mice with autosomal recessive hypercholesterolemia. J Biol Chem (2003) 1.56

Abnormal development of the apical ectodermal ridge and polysyndactyly in Megf7-deficient mice. Hum Mol Genet (2005) 1.56

Interaction of reelin signaling and Lis1 in brain development. Nat Genet (2003) 1.56

Heterozygous alpha 2C-adrenoceptor-deficient mice develop heart failure after transverse aortic constriction. Cardiovasc Res (2007) 1.55

A juvenile form of postsynaptic hippocampal long-term potentiation in mice deficient for the AMPA receptor subunit GluR-A. J Physiol (2003) 1.52

Essential roles for the FE65 amyloid precursor protein-interacting proteins in brain development. EMBO J (2006) 1.51

Laminating the hippocampus. Nat Rev Neurosci (2006) 1.50

Differential glycosylation regulates processing of lipoprotein receptors by gamma-secretase. J Biol Chem (2003) 1.48

Origins of peptide selectivity and phosphoinositide binding revealed by structures of disabled-1 PTB domain complexes. Structure (2003) 1.48

Upregulation of soluble vascular endothelial growth factor receptor 1 contributes to angiogenesis defects in the placenta of alpha 2B-adrenoceptor deficient mice. Circ Res (2007) 1.48

Human apolipoprotein E isoforms differentially affect bone mass and turnover in vivo. J Bone Miner Res (2013) 1.47

Apolipoprotein E induces antiinflammatory phenotype in macrophages. Arterioscler Thromb Vasc Biol (2011) 1.47

Conditional expression of mutant M-line titins results in cardiomyopathy with altered sarcomere structure. J Biol Chem (2002) 1.47

Mediator probe PCR: a novel approach for detection of real-time PCR based on label-free primary probes and standardized secondary universal fluorogenic reporters. Clin Chem (2012) 1.46

Compartment-dependent colocalization of Kir3.2-containing K+ channels and GABAB receptors in hippocampal pyramidal cells. J Neurosci (2006) 1.45

Divergent roles of ApoER2 and Vldlr in the migration of cortical neurons. Development (2007) 1.45

Reelin deficiency and displacement of mature neurons, but not neurogenesis, underlie the formation of granule cell dispersion in the epileptic hippocampus. J Neurosci (2006) 1.45

Cellular uptake of Clostridium difficile toxin B. Translocation of the N-terminal catalytic domain into the cytosol of eukaryotic cells. J Biol Chem (2003) 1.45

Proteomic analysis of GLUT4 storage vesicles reveals LRP1 to be an important vesicle component and target of insulin signaling. J Biol Chem (2009) 1.45

Reelin signaling directly affects radial glia morphology and biochemical maturation. Development (2003) 1.44

Reelin stabilizes the actin cytoskeleton of neuronal processes by inducing n-cofilin phosphorylation at serine3. J Neurosci (2009) 1.44

Role for Reelin-induced cofilin phosphorylation in the assembly of sympathetic preganglionic neurons in the murine intermediolateral column. Eur J Neurosci (2010) 1.44

LRP1 functions as an atheroprotective integrator of TGFbeta and PDFG signals in the vascular wall: implications for Marfan syndrome. PLoS One (2007) 1.44

Progranulin: a proteolytically processed protein at the crossroads of inflammation and neurodegeneration. J Biol Chem (2012) 1.43

The central fragment of Reelin, generated by proteolytic processing in vivo, is critical to its function during cortical plate development. J Neurosci (2004) 1.42

Reelin, Disabled 1, and beta 1 integrins are required for the formation of the radial glial scaffold in the hippocampus. Proc Natl Acad Sci U S A (2002) 1.41

Beta-catenin-mediated cell-adhesion is vital for embryonic forebrain development. Dev Dyn (2005) 1.40

The identification of phosducin as a novel candidate gene for hypertension and its role in sympathetic activation. Curr Opin Nephrol Hypertens (2011) 1.40

Alpha2-adrenergic receptor activation regulates cortical interneuron migration. Eur J Neurosci (2012) 1.38

Gamma-secretase limits the inflammatory response through the processing of LRP1. Sci Signal (2008) 1.38

Microfluidic lab-on-a-foil for nucleic acid analysis based on isothermal recombinase polymerase amplification (RPA). Lab Chip (2010) 1.37

LRP4 mutations alter Wnt/beta-catenin signaling and cause limb and kidney malformations in Cenani-Lenz syndrome. Am J Hum Genet (2010) 1.37

"Dormant basket cell" hypothesis revisited: relative vulnerabilities of dentate gyrus mossy cells and inhibitory interneurons after hippocampal status epilepticus in the rat. J Comp Neurol (2003) 1.36

LRP1 controls intracellular cholesterol storage and fatty acid synthesis through modulation of Wnt signaling. J Biol Chem (2008) 1.36