Joseph A Hill

Author PubWeight™ 260.36‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy 2007 20.92
2 Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy 2012 20.08
3 Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis. Proc Natl Acad Sci U S A 2008 9.86
4 Transient regenerative potential of the neonatal mouse heart. Science 2011 9.02
5 The endothelial-specific microRNA miR-126 governs vascular integrity and angiogenesis. Dev Cell 2008 7.26
6 FGF23 induces left ventricular hypertrophy. J Clin Invest 2011 7.22
7 Class II histone deacetylases act as signal-responsive repressors of cardiac hypertrophy. Cell 2002 7.10
8 Heart repair by reprogramming non-myocytes with cardiac transcription factors. Nature 2012 6.65
9 Cardiac autophagy is a maladaptive response to hemodynamic stress. J Clin Invest 2007 5.17
10 Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis. Nature 2012 4.84
11 Histone deacetylases 1 and 2 redundantly regulate cardiac morphogenesis, growth, and contractility. Genes Dev 2007 4.50
12 Hypertrophy of the heart: a new therapeutic target? Circulation 2004 4.45
13 Histone deacetylases 5 and 9 govern responsiveness of the heart to a subset of stress signals and play redundant roles in heart development. Mol Cell Biol 2004 4.24
14 Fibrosis--a common pathway to organ injury and failure. N Engl J Med 2015 3.94
15 Mitochondrial deficiency and cardiac sudden death in mice lacking the MEF2A transcription factor. Nat Med 2002 3.31
16 Activated glycogen synthase-3 beta suppresses cardiac hypertrophy in vivo. Proc Natl Acad Sci U S A 2002 3.27
17 Reprogramming of human fibroblasts toward a cardiac fate. Proc Natl Acad Sci U S A 2013 3.14
18 Stress-dependent cardiac remodeling occurs in the absence of microRNA-21 in mice. J Clin Invest 2010 3.04
19 Histone deacetylase (HDAC) inhibitors attenuate cardiac hypertrophy by suppressing autophagy. Proc Natl Acad Sci U S A 2011 2.80
20 TRPC6 fulfills a calcineurin signaling circuit during pathologic cardiac remodeling. J Clin Invest 2006 2.74
21 Suppression of class I and II histone deacetylases blunts pressure-overload cardiac hypertrophy. Circulation 2006 2.70
22 The delta isoform of CaM kinase II is required for pathological cardiac hypertrophy and remodeling after pressure overload. Proc Natl Acad Sci U S A 2009 2.66
23 Foxo transcription factors blunt cardiac hypertrophy by inhibiting calcineurin signaling. Circulation 2006 2.55
24 Pathogenesis of myocardial ischemia-reperfusion injury and rationale for therapy. Am J Cardiol 2010 2.52
25 The transcriptional coactivator CAMTA2 stimulates cardiac growth by opposing class II histone deacetylases. Cell 2006 2.26
26 The MEF2D transcription factor mediates stress-dependent cardiac remodeling in mice. J Clin Invest 2008 2.24
27 A dynamic notch injury response activates epicardium and contributes to fibrosis repair. Circ Res 2010 2.23
28 Requirement of protein kinase D1 for pathological cardiac remodeling. Proc Natl Acad Sci U S A 2008 2.12
29 Mice lacking calsarcin-1 are sensitized to calcineurin signaling and show accelerated cardiomyopathy in response to pathological biomechanical stress. Nat Med 2004 2.11
30 FoxO transcription factors activate Akt and attenuate insulin signaling in heart by inhibiting protein phosphatases. Proc Natl Acad Sci U S A 2007 2.08
31 Histone deacetylase inhibition blunts ischemia/reperfusion injury by inducing cardiomyocyte autophagy. Circulation 2014 2.07
32 Autophagy is an adaptive response in desmin-related cardiomyopathy. Proc Natl Acad Sci U S A 2008 2.07
33 Abnormal coronary function in mice deficient in alpha1H T-type Ca2+ channels. Science 2003 2.05
34 Intracellular protein aggregation is a proximal trigger of cardiomyocyte autophagy. Circulation 2008 1.95
35 Macrophages are required for neonatal heart regeneration. J Clin Invest 2014 1.93
36 Impaired autophagosome clearance contributes to cardiomyocyte death in ischemia/reperfusion injury. Circulation 2012 1.91
37 MicroRNA-214 protects the mouse heart from ischemic injury by controlling Ca²⁺ overload and cell death. J Clin Invest 2012 1.90
38 Autophagy in load-induced heart disease. Circ Res 2008 1.89
39 Increased ER-mitochondrial coupling promotes mitochondrial respiration and bioenergetics during early phases of ER stress. J Cell Sci 2011 1.65
40 Metabolic stress-induced activation of FoxO1 triggers diabetic cardiomyopathy in mice. J Clin Invest 2012 1.63
41 Modulation of adverse cardiac remodeling by STARS, a mediator of MEF2 signaling and SRF activity. J Clin Invest 2007 1.50
42 Does load-induced ventricular hypertrophy progress to systolic heart failure? Am J Physiol Heart Circ Physiol 2005 1.50
43 Autophagy as a therapeutic target in cardiovascular disease. J Mol Cell Cardiol 2011 1.48
44 Pathological ventricular remodeling: mechanisms: part 1 of 2. Circulation 2013 1.48
45 C/EBP transcription factors mediate epicardial activation during heart development and injury. Science 2012 1.48
46 Endometriosis and subfertility: is the relationship resolved? Semin Reprod Med 2003 1.48
47 Calcineurin is necessary for the maintenance but not embryonic development of slow muscle fibers. Mol Cell Biol 2005 1.47
48 Physical and functional interaction between calcineurin and the cardiac L-type Ca2+ channel. Circ Res 2009 1.42
49 Enhanced autophagy ameliorates cardiac proteinopathy. J Clin Invest 2013 1.41
50 Cardiovascular side effects of cancer therapies: a position statement from the Heart Failure Association of the European Society of Cardiology. Eur J Heart Fail 2011 1.40
51 Differential activation of stress-response signaling in load-induced cardiac hypertrophy and failure. Physiol Genomics 2005 1.39
52 Cardiac myosin light chain kinase is necessary for myosin regulatory light chain phosphorylation and cardiac performance in vivo. J Biol Chem 2010 1.37
53 Diabetic Cardiomyopathy: Mechanisms and Therapeutic Targets. Drug Discov Today Dis Mech 2010 1.28
54 The Xbp1s/GalE axis links ER stress to postprandial hepatic metabolism. J Clin Invest 2012 1.23
55 Endoplasmic reticulum and the unfolded protein response: dynamics and metabolic integration. Int Rev Cell Mol Biol 2013 1.23
56 STIM1-dependent store-operated Ca²⁺ entry is required for pathological cardiac hypertrophy. J Mol Cell Cardiol 2011 1.18
57 Ca2+/calmodulin-dependent protein kinase II-dependent remodeling of Ca2+ current in pressure overload heart failure. J Biol Chem 2008 1.16
58 Autophagy in hypertensive heart disease. J Biol Chem 2010 1.15
59 Autophagy in cardiovascular biology. J Clin Invest 2015 1.14
60 The histone trimethyllysine demethylase JMJD2A promotes cardiac hypertrophy in response to hypertrophic stimuli in mice. J Clin Invest 2011 1.13
61 FoxO, autophagy, and cardiac remodeling. J Cardiovasc Transl Res 2010 1.11
62 Myocyte autophagy in heart disease: friend or foe? Autophagy 2007 1.09
63 Adipose tissue biology and cardiomyopathy: translational implications. Circ Res 2012 1.05
64 Electrophysiological remodeling in heart failure. J Mol Cell Cardiol 2010 1.05
65 Tuning flux: autophagy as a target of heart disease therapy. Curr Opin Cardiol 2011 1.05
66 Histone deacetylase inhibition in the treatment of heart disease. Expert Opin Drug Saf 2008 1.04
67 Doxycycline attenuates isoproterenol- and transverse aortic banding-induced cardiac hypertrophy in mice. J Pharmacol Exp Ther 2007 1.04
68 Energy-preserving effects of IGF-1 antagonize starvation-induced cardiac autophagy. Cardiovasc Res 2011 1.03
69 Reversibility of adverse, calcineurin-dependent cardiac remodeling. Circ Res 2011 1.03
70 Insulin stimulates mitochondrial fusion and function in cardiomyocytes via the Akt-mTOR-NFκB-Opa-1 signaling pathway. Diabetes 2013 1.01
71 Cx30.2 enhancer analysis identifies Gata4 as a novel regulator of atrioventricular delay. Development 2009 1.01
72 Diabetic cardiomyopathy and metabolic remodeling of the heart. Life Sci 2012 1.00
73 HDAC-dependent ventricular remodeling. Trends Cardiovasc Med 2013 1.00
74 FHL2 binds calcineurin and represses pathological cardiac growth. Mol Cell Biol 2012 1.00
75 The CCAAT/enhancer binding protein beta (C/EBPbeta) cooperates with NFAT to control expression of the calcineurin regulatory protein RCAN1-4. J Biol Chem 2010 1.00
76 Remodeling of early-phase repolarization: a mechanism of abnormal impulse conduction in heart failure. Circulation 2006 0.99
77 Dual control of cardiac Na+ Ca2+ exchange by PIP(2): analysis of the surface membrane fraction by extracellular cysteine PEGylation. J Physiol 2007 0.97
78 COCATS 4 Task Force 15: Training in Cardiovascular Research and Scholarly Activity. J Am Coll Cardiol 2015 0.97
79 Transient-outward K+ channel inhibition facilitates L-type Ca2+ current in heart. J Cardiovasc Electrophysiol 2006 0.97
80 New autophagy reporter mice reveal dynamics of proximal tubular autophagy. J Am Soc Nephrol 2013 0.95
81 Guidelines for translational research in heart failure. J Cardiovasc Transl Res 2015 0.95
82 Cardiomyocyte autophagy: remodeling, repairing, and reconstructing the heart. Curr Hypertens Rep 2009 0.95
83 Remodeling of outward K+ currents in pressure-overload heart failure. J Cardiovasc Electrophysiol 2007 0.95
84 Mechanical unloading activates FoxO3 to trigger Bnip3-dependent cardiomyocyte atrophy. J Am Heart Assoc 2013 0.94
85 Targeting of protein phosphatases PP2A and PP2B to the C-terminus of the L-type calcium channel Ca v1.2. Biochemistry 2010 0.93
86 Diminished cardiac fibrosis in heart failure is associated with altered ventricular arrhythmia phenotype. J Cardiovasc Electrophysiol 2010 0.92
87 Detection of implantation-related cytokines in cervicovaginal secretions and peripheral blood of fertile women during ovulatory menstrual cycles. Fertil Steril 2004 0.92
88 Myocyte enhancer factor 2 and class II histone deacetylases control a gender-specific pathway of cardioprotection mediated by the estrogen receptor. Circ Res 2009 0.90
89 Fibrosis--A Common Pathway to Organ Injury and Failure. N Engl J Med 2015 0.90
90 Pathological ventricular remodeling: therapies: part 2 of 2. Circulation 2013 0.90
91 Sustained hemodynamic stress disrupts normal circadian rhythms in calcineurin-dependent signaling and protein phosphorylation in the heart. Circ Res 2011 0.89
92 The complex interplay between mitochondrial dynamics and cardiac metabolism. J Bioenerg Biomembr 2011 0.89
93 Hic-5 is required for fetal gene expression and cytoskeletal organization of neonatal cardiac myocytes. J Mol Cell Cardiol 2009 0.89
94 Reactive oxygen species suppress cardiac NaV1.5 expression through Foxo1. PLoS One 2012 0.89
95 Second statement of the working group on electrocardiographic diagnosis of left ventricular hypertrophy. J Electrocardiol 2011 0.88
96 Forkhead factor FoxO1 is essential for placental morphogenesis in the developing embryo. Proc Natl Acad Sci U S A 2011 0.88
97 Mitochondrial fission and autophagy in the normal and diseased heart. Curr Hypertens Rep 2010 0.88
98 The heart of autophagy: deconstructing cardiac proteotoxicity. Autophagy 2008 0.87
99 Oxidative stress and autophagy in cardiovascular homeostasis. Antioxid Redox Signal 2013 0.86
100 Regulation of atrial natriuretic peptide secretion by a novel Ras-like protein. J Cell Biol 2007 0.85
101 RalGDS-dependent cardiomyocyte autophagy is required for load-induced ventricular hypertrophy. J Mol Cell Cardiol 2013 0.84
102 Cardiomyocyte ryanodine receptor degradation by chaperone-mediated autophagy. Cardiovasc Res 2013 0.84
103 Effect of spironolactone on patients with atrial fibrillation and structural heart disease. Clin Cardiol 2011 0.83
104 Comparison of gene expression at the feto-maternal interface between normal and recurrent pregnancy loss patients. Reprod Fertil Dev 2002 0.83
105 The effects of neuregulin on cardiac Myosin light chain kinase gene-ablated hearts. PLoS One 2013 0.83
106 Cardiac autophagy: good with the bad. J Cardiovasc Pharmacol 2012 0.83
107 Autophagy in load-induced heart disease. Methods Enzymol 2009 0.82
108 MicroRNAs and heart failure diagnosis: MiR-acle or MiR-age? Circ Res 2010 0.81
109 Cardiomyocyte autophagy: metabolic profit and loss. Heart Fail Rev 2013 0.81
110 Role of Korean red ginseng total saponins in rat infertility induced by polycystic ovaries. Fertil Steril 2005 0.81
111 Spironolactone therapy is associated with reduced ventricular tachycardia rate in patients with cardiomyopathy. Pacing Clin Electrophysiol 2010 0.79
112 Heart failure and loss of metabolic control. J Cardiovasc Pharmacol 2014 0.79
113 Maternal CD46H*2 and IL1B-511*1 homozygosity in T helper 1-type immunity to trophoblast antigens in recurrent pregnancy loss. Hum Reprod 2005 0.78
114 HFSA and AAHFN joint position statement: advocating for a full scope of nursing practice and leadership in heart failure. J Card Fail 2012 0.78
115 Carbamazepine alone and in combination with doxycycline attenuates isoproterenol-induced cardiac hypertrophy. Heart Int 2010 0.78
116 Regulation of cardiac autophagy by insulin-like growth factor 1. IUBMB Life 2013 0.78
117 Future directions in endometriosis research. Obstet Gynecol Clin North Am 2003 0.78
118 Human atrial chloride channels: swelling with pride. J Cardiovasc Electrophysiol 2006 0.78
119 NEMO nuances NF-kappaB. Circ Res 2010 0.78
120 Trophoblast apoptosis is increased in women with evidence of TH1 immunity. Fertil Steril 2005 0.77
121 Braking bad hypertrophy. N Engl J Med 2015 0.77
122 Expression of membrane-bound HLA-G at the maternal-fetal interface is not associated with pregnancy maintenance among patients with idiopathic recurrent pregnancy loss. Mol Hum Reprod 2003 0.77
123 In-vitro adhesion of endometrium to autologous peritoneal membranes: effect of the cycle phase and the stage of endometriosis. Hum Reprod 2002 0.77
124 Tumour necrosis factor-alpha, interleukin-6 and interleukin-8 do not promote adhesion of human endometrial epithelial cells to mesothelial cells in a quantitative in vitro model. Hum Reprod 2005 0.77
125 President's page: an urgent call to action: graduate medical education funding and the future of health care. J Am Coll Cardiol 2013 0.76
126 Epigenetic regulation in heart failure. Curr Opin Cardiol 2016 0.76
127 Titrating autophagy in cardiac plasticity. Autophagy 2011 0.76
128 T-helper 2 and 3 type immunity to trophoblast in successful in vitro fertilization-embryo transfer. Fertil Steril 2005 0.76
129 Funny and late: targeting currents governing heart rate in atrial fibrillation. J Cardiovasc Electrophysiol 2015 0.75
130 Response to Crozatier and Ventura-Clapier. Circulation 2015 0.75
131 HDACs and hypertrophy, kinases and cancer. Circulation 2011 0.75
132 FoxO1 in embryonic development. Transcription 2012 0.75
133 PKG primes the proteasome. Circulation 2013 0.75
134 Adenosine A3 receptor and cardioprotection: enticing, enigmatic, elusive. Circulation 2008 0.75
135 President's page: The perfect storm part 2: a rally cry for medical research funding. J Am Coll Cardiol 2013 0.75
136 Guanosine triphosphatase activation occurs downstream of calcineurin in cardiac hypertrophy*. J Investig Med 2005 0.75
137 Fundamental Cardiovascular Research: Returns on Societal Investment: A Scientific Statement From the American Heart Association. Circ Res 2017 0.75
138 HFSA and AAHFN joint position statement: advocating for a full scope of nursing practice and leadership in heart failure. Heart Lung 2012 0.75
139 Changing role of ECG in the evaluation left ventricular hypertrophy. J Electrocardiol 2012 0.75
140 Atypical chest pain and atypical coronary artery disease. Am J Cardiol 2003 0.75