Published in J Immunol on November 05, 2010
mTOR, metabolism, and the regulation of T-cell differentiation and function. Immunol Rev (2012) 1.74
Metabolic control of the Treg/Th17 axis. Immunol Rev (2013) 1.26
Systems modeling of molecular mechanisms controlling cytokine-driven CD4+ T cell differentiation and phenotype plasticity. PLoS Comput Biol (2013) 1.01
Predictive computational modeling of the mucosal immune responses during Helicobacter pylori infection. PLoS One (2013) 0.94
Modulation of T Cell Metabolism and Function through Calcium Signaling. Front Immunol (2013) 0.93
Nutrient Sensing via mTOR in T Cells Maintains a Tolerogenic Microenvironment. Front Immunol (2014) 0.89
Retinoid and TGF-β families: crosstalk in development, neoplasia, immunity, and tissue repair. Semin Nephrol (2012) 0.85
Attenuation of islet-specific T cell responses is associated with C-peptide improvement in autoimmune type 2 diabetes patients. Clin Exp Immunol (2013) 0.84
The role of lipoxin A4 in endometrial biology and endometriosis. Mucosal Immunol (2013) 0.83
Peroxisome proliferator-activated receptor gamma is required for CD4+ T cell-mediated lymphopenia-associated autoimmunity. J Immunol (2011) 0.83
High beta-palmitate fat controls the intestinal inflammatory response and limits intestinal damage in mucin Muc2 deficient mice. PLoS One (2013) 0.82
The role of nuclear receptors in regulation of Th17/Treg biology and its implications for diseases. Cell Mol Immunol (2015) 0.82
FOXP3 Expression in GARP-Transduced Helper T Cells Is Not Associated with FOXP3 TSDR Demethylation. Transfus Med Hemother (2011) 0.77
Fenofibrate enhances the in vitro differentiation of foxp3(+) regulatory T cells in mice. PPAR Res (2012) 0.76
Role of Peroxisome Proliferator-Activated Receptor-γ in Vascular Inflammation. Int J Vasc Med (2012) 0.76
Time-Qualified Patterns of Variation of PPARγ, DNMT1, and DNMT3B Expression in Pancreatic Cancer Cell Lines. PPAR Res (2012) 0.76
Therapeutic Treatment of Arthritic Mice with 15-Deoxy Δ(12,14)-Prostaglandin J2 (15d-PGJ2) Ameliorates Disease through the Suppression of Th17 Cells and the Induction of CD4(+)CD25(-)FOXP3(+) Cells. Mediators Inflamm (2016) 0.75
Development of functional human blood and immune systems in NOD/SCID/IL2 receptor {gamma} chain(null) mice. Blood (2005) 6.16
The first identification and retrospective study of Severe Fever with Thrombocytopenia Syndrome in Japan. J Infect Dis (2013) 4.92
Engineering tumors with 3D scaffolds. Nat Methods (2007) 3.96
A human transporter protein that mediates the final excretion step for toxic organic cations. Proc Natl Acad Sci U S A (2005) 2.34
Malaria blood stage parasites activate human plasmacytoid dendritic cells and murine dendritic cells through a Toll-like receptor 9-dependent pathway. J Immunol (2004) 2.33
Generation of functional human T-cell subsets with HLA-restricted immune responses in HLA class I expressing NOD/SCID/IL2r gamma(null) humanized mice. Proc Natl Acad Sci U S A (2010) 2.24
Molecular signatures distinguish human central memory from effector memory CD8 T cell subsets. J Immunol (2005) 2.12
The MATE proteins as fundamental transporters of metabolic and xenobiotic organic cations. Trends Pharmacol Sci (2006) 2.03
Nationwide survey of hemophagocytic lymphohistiocytosis in Japan. Int J Hematol (2007) 1.90
Non-viral gene delivery regulated by stiffness of cell adhesion substrates. Nat Mater (2005) 1.83
Identification of N-arachidonylglycine as the endogenous ligand for orphan G-protein-coupled receptor GPR18. Biochem Biophys Res Commun (2006) 1.79
Antagonist of interferon-inducible protein 10/CXCL10 ameliorates the progression of autoimmune sialadenitis in MRL/lpr mice. Arthritis Rheum (2006) 1.56
Improved expression and reactivity of transduced tumor-specific TCRs in human lymphocytes by specific silencing of endogenous TCR. Cancer Res (2009) 1.55
Aurora kinase A-specific T-cell receptor gene transfer redirects T lymphocytes to display effective antileukemia reactivity. Blood (2011) 1.54
Prediction of strength and strain of the proximal femur by a CT-based finite element method. J Biomech (2006) 1.53
Regulatory/effector T-cell ratio is reduced in coronary artery disease. Circ J (2014) 1.44
Potentiation of the ligand-binding activity of integrin alpha3beta1 via association with tetraspanin CD151. Proc Natl Acad Sci U S A (2005) 1.44
Frequent expression of CCR4 in adult T-cell leukemia and human T-cell leukemia virus type 1-transformed T cells. Blood (2002) 1.42
Essential role of the N-terminus of murine Orai1 in store-operated Ca2+ entry. Biochem Biophys Res Commun (2007) 1.40
Genetic subtypes of familial hemophagocytic lymphohistiocytosis: correlations with clinical features and cytotoxic T lymphocyte/natural killer cell functions. Blood (2005) 1.37
HLA class I binding of HBZ determines outcome in HTLV-1 infection. PLoS Pathog (2010) 1.28
CD151 regulates epithelial cell-cell adhesion through PKC- and Cdc42-dependent actin cytoskeletal reorganization. J Cell Biol (2003) 1.26
CD151 enhances cell motility and metastasis of cancer cells in the presence of focal adhesion kinase. Int J Cancer (2002) 1.26
Perforin gene mutations in adult-onset hemophagocytic lymphohistiocytosis. Haematologica (2007) 1.21
Autocrine and paracrine chemokine receptor 7 activation in head and neck cancer: implications for therapy. J Natl Cancer Inst (2008) 1.19
Wilms tumor gene peptide-based immunotherapy for patients with overt leukemia from myelodysplastic syndrome (MDS) or MDS with myelofibrosis. Int J Hematol (2003) 1.18
Cross-coupling reactions through the intramolecular activation of alkyl(triorgano)silanes. Angew Chem Int Ed Engl (2010) 1.16
A mitotic kinase TOPK enhances Cdk1/cyclin B1-dependent phosphorylation of PRC1 and promotes cytokinesis. J Mol Biol (2007) 1.14
Generation of tumor-specific, HLA class I-restricted human Th1 and Tc1 cells by cell engineering with tumor peptide-specific T-cell receptor genes. Blood (2005) 1.10
Novel adoptive T-cell immunotherapy using a WT1-specific TCR vector encoding silencers for endogenous TCRs shows marked antileukemia reactivity and safety. Blood (2011) 1.10
Review of hemophagocytic lymphohistiocytosis (HLH) in children with focus on Japanese experiences. Crit Rev Oncol Hematol (2005) 1.09
Aurora-A kinase: a novel target of cellular immunotherapy for leukemia. Blood (2008) 1.09
Antagonist of fractalkine (CX3CL1) delays the initiation and ameliorates the progression of lupus nephritis in MRL/lpr mice. Arthritis Rheum (2005) 1.09
Enhanced induction of human WT1-specific cytotoxic T lymphocytes with a 9-mer WT1 peptide modified at HLA-A*2402-binding residues. Cancer Immunol Immunother (2002) 1.08
Chondroitin sulfate B exerts its inhibitory effect on secondary lymphoid tissue chemokine (SLC) by binding to the C-terminus of SLC. Biochim Biophys Acta (2002) 1.08
Identification of cutaneous lymphocyte-associated antigen as sialyl 6-sulfo Lewis X, a selectin ligand expressed on a subset of skin-homing helper memory T cells. Blood (2005) 1.07
Resistin SNP-420 determines its monocyte mRNA and serum levels inducing type 2 diabetes. Biochem Biophys Res Commun (2005) 1.07
A Cenozoic record of the equatorial Pacific carbonate compensation depth. Nature (2012) 1.04
Cranial nerve palsy following transvenous embolization for a cavernous sinus dural arteriovenous fistula: association with the volume and location of detachable coils. J Neurosurg (2008) 1.03
HBZ is an immunogenic protein, but not a target antigen for human T-cell leukemia virus type 1-specific cytotoxic T lymphocytes. J Gen Virol (2009) 1.00
An analysis of the persistent presence of opportunistic pathogens on patient-derived dental impressions and gypsum casts. Int J Prosthodont (2008) 1.00
Pitavastatin inhibits upregulation of intermediate conductance calcium-activated potassium channels and coronary arteriolar remodeling induced by long-term blockade of nitric oxide synthesis. Pharmacology (2003) 0.99
Gingival fibroblasts as a promising source of induced pluripotent stem cells. PLoS One (2010) 0.98
Wide variety of locations for rodent MATE1, a transporter protein that mediates the final excretion step for toxic organic cations. Am J Physiol Cell Physiol (2006) 0.96
Gemcitabine enhances Wilms' tumor gene WT1 expression and sensitizes human pancreatic cancer cells with WT1-specific T-cell-mediated antitumor immune response. Cancer Immunol Immunother (2011) 0.96
CD151 forms a functional complex with c-Met in human salivary gland cancer cells. Biochem Biophys Res Commun (2005) 0.96
The expression of the aurora-A gene and its significance with tumorgenesis in non-Hodgkin's lymphoma. Leuk Lymphoma (2004) 0.96
Aurora2/BTAK/STK15 is involved in cell cycle checkpoint and cell survival of aggressive non-Hodgkin's lymphoma. Br J Haematol (2003) 0.95
Endothelial adhesion molecules in glomerular lesions: association with their severity and diversity in lupus models. Kidney Int (2004) 0.95
Novel RUNX1-PRDM16 fusion transcripts in a patient with acute myeloid leukemia showing t(1;21)(p36;q22). Genes Chromosomes Cancer (2005) 0.95
The role of zinc finger protein 521/early hematopoietic zinc finger protein in erythroid cell differentiation. J Biol Chem (2008) 0.95
Clinical evaluation of the efficacy of removing microorganisms to disinfect patient-derived dental impressions. Int J Prosthodont (2009) 0.95
Phenotypic and functional alterations of dendritic cells induced by human herpesvirus 6 infection. J Virol (2002) 0.95
[Toxicity and toxin profile of tetrodotoxin detected in the scavenging gastropod Nassarius (Alectrion) glans "Kinshibai"]. Shokuhin Eiseigaku Zasshi (2009) 0.95
Relationship between 18F-fluorodeoxyglucose accumulation and KRAS/BRAF mutations in colorectal cancer. Clin Cancer Res (2012) 0.93
Development of a novel redirected T-cell-based adoptive immunotherapy targeting human telomerase reverse transcriptase for adult T-cell leukemia. Blood (2013) 0.93
Characterization of the human MATE2 proton-coupled polyspecific organic cation exporter. Int J Biochem Cell Biol (2011) 0.93
Hydrogel-based biomimetic environment for in vitro modulation of branching morphogenesis. Biomaterials (2011) 0.92
Effect of calcium ion concentrations on osteogenic differentiation and hematopoietic stem cell niche-related protein expression in osteoblasts. Tissue Eng Part A (2010) 0.92
DVC1-0101 to treat peripheral arterial disease: a Phase I/IIa open-label dose-escalation clinical trial. Mol Ther (2013) 0.91
Fractalkine expression and CD16+ monocyte accumulation in glomerular lesions: association with their severity and diversity in lupus models. Am J Physiol Renal Physiol (2010) 0.91
The sleep-enhancing effect of valerian inhalation and sleep-shortening effect of lemon inhalation. Chem Senses (2006) 0.91
CD151 regulates HGF-stimulated morphogenesis of human breast cancer cells. Biochem Biophys Res Commun (2009) 0.90
Human cord blood- and bone marrow-derived CD34+ cells regenerate gastrointestinal epithelial cells. FASEB J (2004) 0.90
Therapy for pneumonitis and sialadenitis by accumulation of CCR2-expressing CD4+CD25+ regulatory T cells in MRL/lpr mice. Arthritis Res Ther (2007) 0.90
WT1 peptide-based immunotherapy for patients with lung cancer: report of two cases. Microbiol Immunol (2004) 0.90
A novel fusion variant of the MORF and CBP genes detected in therapy-related myelodysplastic syndrome with t(10;16)(q22;p13). Br J Haematol (2003) 0.89
Loss of SMAD4 from colorectal cancer cells promotes CCL15 expression to recruit CCR1+ myeloid cells and facilitate liver metastasis. Gastroenterology (2013) 0.89
Co-introduced functional CCR2 potentiates in vivo anti-lung cancer functionality mediated by T cells double gene-modified to express WT1-specific T-cell receptor. PLoS One (2013) 0.89
A directly fused tetrameric porphyrin sheet and its anomalous electronic properties that arise from the planar cyclooctatetraene core. J Am Chem Soc (2006) 0.89
Maximum standard uptake value of 18F-fluorodeoxyglucose positron emission tomography is a prognostic factor for progression-free survival of newly diagnosed patients with diffuse large B cell lymphoma. Ann Hematol (2012) 0.89
Wilms tumor gene WT1 peptide-based immunotherapy induced a minimal response in a patient with advanced therapy-resistant multiple myeloma. Int J Hematol (2007) 0.89
Cooperative role of the membrane-proximal and -distal residues of the integrin beta3 cytoplasmic domain in regulation of talin-mediated alpha IIb beta3 activation. J Biol Chem (2008) 0.89
Enhanced bone regeneration via multimodal actions of synthetic peptide SVVYGLR on osteoprogenitors and osteoclasts. Biomaterials (2009) 0.88
A new four-way variant t(5;17;15;20)(q33;q12;q22;q11.2) in acute promyelocytic leukemia. Int J Hematol (2011) 0.88
Differential regulation of perforin expression in human CD4+ and CD8+ cytotoxic T lymphocytes. Exp Hematol (2005) 0.88
Remitting seronegative symmetric synovitis with pitting edema: scintigraphic and magnetic resonance imaging findings. Clin Nucl Med (2003) 0.87
Automated measurement of mandibular cortical width on dental panoramic radiographs. Int J Comput Assist Radiol Surg (2012) 0.87
Direct recognition and lysis of leukemia cells by WT1-specific CD4+ T lymphocytes in an HLA class II-restricted manner. Blood (2005) 0.87
Myeloma cells are highly sensitive to the granule exocytosis pathway mediated by WT1-specific cytotoxic T lymphocytes. Clin Cancer Res (2004) 0.87
[A Fatal Case of Severe Fever with Thrombocytopenia Syndrome Complicated by Hemophagocytic Lymphohistiocytosis]. Kansenshogaku Zasshi (2015) 0.87
In vitro reproduction of endochondral ossification using a 3D mesenchymal stem cell construct. Integr Biol (Camb) (2012) 0.87
Role of augmented expression of intermediate-conductance Ca2+-activated K+ channels in postischaemic heart. Clin Exp Pharmacol Physiol (2002) 0.87
Human cord blood--derived cells generate insulin-producing cells in vivo. Stem Cells (2005) 0.86
Origins of plastids and glyceraldehyde-3-phosphate dehydrogenase genes in the green-colored dinoflagellate Lepidodinium chlorophorum. Gene (2007) 0.86
Expression of SOCS3 mRNA in bone marrow cells from CML patients associated with cytogenetic response to IFN-alpha. Leuk Res (2005) 0.86
Effects of single and repeated prolonged stress on mu-opioid receptor mRNA expression in rat gross hypothalamic and midbrain homogenates. Brain Res (2003) 0.86
Effects of quetiapine on monoamine, GABA, and glutamate release in rat prefrontal cortex. Psychopharmacology (Berl) (2009) 0.86
Measurement of mechanical properties on gap healing in a rabbit osteotomy model until the remodeling stage. Clin Biomech (Bristol, Avon) (2011) 0.86
Double transgenic mice crossed GFP-LC3 transgenic mice with alphaMyHC-mCherry-LC3 transgenic mice are a new and useful tool to examine the role of autophagy in the heart. Circ J (2009) 0.86
Osteopontin-derived peptide SVVYGLR induces angiogenesis in vivo. Dent Mater J (2004) 0.86
Physician's Perceptions of Interprofessional Collaboration in Clinical Training Hospitals in Northeastern Japan. J Clin Med Res (2013) 0.85
Subtypes of familial hemophagocytic lymphohistiocytosis in Japan based on genetic and functional analyses of cytotoxic T lymphocytes. PLoS One (2010) 0.85
Skin irritants and contact sensitizers induce Langerhans cell migration and maturation at irritant concentration. Exp Dermatol (2006) 0.85