Published in J Immunol on November 08, 2010
Peptides released by physiological cleavage of semen coagulum proteins form amyloids that enhance HIV infection. Cell Host Microbe (2011) 1.72
Naturally occurring fragments from two distinct regions of the prostatic acid phosphatase form amyloidogenic enhancers of HIV infection. J Virol (2011) 1.42
CCR5 expression is elevated on endocervical CD4+ T cells in healthy postmenopausal women. J Acquir Immune Defic Syndr (2012) 1.01
Seminal plasma accelerates semen-derived enhancer of viral infection (SEVI) fibril formation by the prostatic acid phosphatase (PAP248-286) peptide. J Biol Chem (2012) 0.98
The Surprising Role of Amyloid Fibrils in HIV Infection. Biology (Basel) (2012) 0.91
Development of HIV-1 rectal-specific microbicides and colonic tissue evaluation. PLoS One (2014) 0.86
Characterization of the Influence of Semen-Derived Enhancer of Virus Infection on the Interaction of HIV-1 with Female Reproductive Tract Tissues. J Virol (2015) 0.82
X4 tropic multi-drug resistant quasi-species detected at the time of primary HIV-1 infection remain exclusive or at least dominant far from PHI. PLoS One (2011) 0.77
Human seminal plasma fosters CD4(+) regulatory T-cell phenotype and transforming growth factor-β1 expression. Am J Reprod Immunol (2012) 0.77
Comparison of the effect of semen from HIV-infected and uninfected men on CD4+ T-cell infection. AIDS (2016) 0.75
The regulation of inflammatory pathways and infectious disease of the cervix by seminal fluid. Patholog Res Int (2014) 0.75
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods (2001) 414.27
Universal voluntary HIV testing with immediate antiretroviral therapy as a strategy for elimination of HIV transmission: a mathematical model. Lancet (2008) 36.01
The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus. Nature (1985) 30.47
T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV. Nature (1985) 21.57
Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection. Proc Natl Acad Sci U S A (2008) 16.54
Genotypic and phenotypic characterization of HIV-1 patients with primary infection. Science (1993) 13.87
HIV preferentially infects HIV-specific CD4+ T cells. Nature (2002) 9.28
Selective transmission of human immunodeficiency virus type-1 variants from mothers to infants. Science (1992) 7.44
The role of sexually transmitted diseases in HIV transmission. Nat Rev Microbiol (2004) 7.04
Initial events in establishing vaginal entry and infection by human immunodeficiency virus type-1. Immunity (2007) 6.36
Semen-derived amyloid fibrils drastically enhance HIV infection. Cell (2007) 5.23
Targeting early infection to prevent HIV-1 mucosal transmission. Nature (2010) 5.05
Regulatory pathways governing HIV-1 replication. Cell (1989) 4.97
Macrophage-tropic variants initiate human immunodeficiency virus type 1 infection after sexual, parenteral, and vertical transmission. J Clin Invest (1994) 4.63
Persistence of HIV-1 receptor-positive cells after HSV-2 reactivation is a potential mechanism for increased HIV-1 acquisition. Nat Med (2009) 4.03
Avoiding the void: cell-to-cell spread of human viruses. Nat Rev Microbiol (2008) 3.79
Amplified transmission of HIV-1: comparison of HIV-1 concentrations in semen and blood during acute and chronic infection. AIDS (2007) 3.72
Transmission, acute HIV-1 infection and the quest for strategies to prevent infection. Nat Med (2003) 3.48
Inefficient human immunodeficiency virus replication in mobile lymphocytes. J Virol (2006) 3.26
Setting the stage: host invasion by HIV. Nat Rev Immunol (2008) 3.25
Selective transmission of CCR5-utilizing HIV-1: the 'gatekeeper' problem resolved? Nat Rev Microbiol (2006) 3.13
Measuring HIV neutralization in a luciferase reporter gene assay. Methods Mol Biol (2009) 2.95
Persistent HIV RNA shedding in semen despite effective antiretroviral therapy. AIDS (2009) 2.77
Cell-to-cell spread of HIV-1 occurs within minutes and may not involve the participation of virus particles. Virology (1992) 2.71
Roles of substrate availability and infection of resting and activated CD4+ T cells in transmission and acute simian immunodeficiency virus infection. Proc Natl Acad Sci U S A (2004) 2.57
Micro- and macrorheology of mucus. Adv Drug Deliv Rev (2009) 2.54
Human immunodeficiency virus type 1 is trapped by acidic but not by neutralized human cervicovaginal mucus. J Virol (2009) 2.49
A new strategy to understand how HIV infects women: identification of a window of vulnerability during the menstrual cycle. AIDS (2008) 2.43
Detection of HIV-1 RNA in seminal plasma samples from treated patients with undetectable HIV-1 RNA in blood plasma. AIDS (2008) 2.27
CD4 downregulation by memory CD4+ T cells in vivo renders African green monkeys resistant to progressive SIVagm infection. Nat Med (2009) 1.81
Seminal plasma and male factor signalling in the female reproductive tract. Cell Tissue Res (2005) 1.77
The origins of sexually transmitted HIV among men who have sex with men. Sci Transl Med (2010) 1.76
Semen-mediated enhancement of HIV infection is donor-dependent and correlates with the levels of SEVI. Retrovirology (2010) 1.70
Increased levels of immune activation in the genital tract of healthy young women from sub-Saharan Africa. AIDS (2010) 1.47
Trappin-2/Elafin: a novel innate anti-human immunodeficiency virus-1 molecule of the human female reproductive tract. Immunology (2009) 1.37
Investigation of microtrauma after sexual intercourse. J Reprod Med (1984) 1.36
Seminal fluid drives expansion of the CD4+CD25+ T regulatory cell pool and induces tolerance to paternal alloantigens in mice. Biol Reprod (2009) 1.36
HIV-1 persists in breast milk cells despite antiretroviral treatment to prevent mother-to-child transmission. AIDS (2008) 1.36
Cationic polypeptides contribute to the anti-HIV-1 activity of human seminal plasma. FASEB J (2009) 1.33
Spermatozoa capture HIV-1 through heparan sulfate and efficiently transmit the virus to dendritic cells. J Exp Med (2009) 1.24
Infection of macaques after vaginal exposure to cell-associated simian immunodeficiency virus. J Infect Dis (2010) 1.23
Human seminal plasma abrogates the capture and transmission of human immunodeficiency virus type 1 to CD4+ T cells mediated by DC-SIGN. J Virol (2007) 1.23
Partial inhibition of human immunodeficiency virus replication by type I interferons: impact of cell-to-cell viral transfer. J Virol (2009) 1.21
VARIANCE ESTIMATION IN THE REED-MUENCH FIFTY PER CENT END-POINT DETERMINATION. Am J Hyg (1964) 1.19
Selective transmission of R5 HIV-1 over X4 HIV-1 at the dendritic cell-T cell infectious synapse is determined by the T cell activation state. PLoS Pathog (2009) 1.11
Viruses within the Flaviviridae decrease CD4 expression and inhibit HIV replication in human CD4+ cells. J Immunol (2009) 1.10
Vaginal pH neutralization by semen as a cofactor of HIV transmission. Clin Microbiol Infect (1997) 1.07
High GUD incidence in the early 20 century created a particularly permissive time window for the origin and initial spread of epidemic HIV strains. PLoS One (2010) 1.03
Mucin 6 in seminal plasma binds DC-SIGN and potently blocks dendritic cell mediated transfer of HIV-1 to CD4(+) T-lymphocytes. Virology (2009) 1.01
Human uterine natural killer cells but not blood natural killer cells inhibit human immunodeficiency virus type 1 infection by secretion of CXCL12. J Virol (2009) 0.99
Seminal plasma induces programmed cell death in cultured peripheral blood mononuclear cells. AIDS Res Hum Retroviruses (2002) 0.97
The role of semen in induction of maternal immune tolerance to pregnancy. Semin Immunol (2001) 0.96
Low-level CD4+ T cell activation in HIV-exposed seronegative subjects: influence of gender and condom use. J Infect Dis (2010) 0.94
Quantitation of HIV-1-specific IgG, IgA, and IgM antibodies in human genital tract secretions. J Acquir Immune Defic Syndr Hum Retrovirol (1997) 0.93
HIV-1 in semen: determination of proviral and viral titres compared to blood, and quantification of semen leukocyte populations. J Med Virol (1999) 0.92
Six-day randomized safety trial of intravaginal lime juice. J Acquir Immune Defic Syndr (2008) 0.91
Mucosal immunity to HIV: a review of recent literature. Curr Opin HIV AIDS (2008) 0.89
CD4-anchoring HIV-1 fusion inhibitor with enhanced potency and in vivo stability. J Biol Chem (2008) 0.86
Spermatozoa--their persistence after sexual intercourse. Forensic Sci Int (1982) 0.86
Methods for the detection of male genital tract inflammation. Andrologia (1998) 0.78
Prevalence and diversity of microbes in the amniotic fluid, the fetal inflammatory response, and pregnancy outcome in women with preterm pre-labor rupture of membranes. Am J Reprod Immunol (2010) 1.74
Anti-HIV activity in cervical-vaginal secretions from HIV-positive and -negative women correlate with innate antimicrobial levels and IgG antibodies. PLoS One (2010) 1.73
Prevalence of toxic shock syndrome toxin 1-producing Staphylococcus aureus and the presence of antibodies to this superantigen in menstruating women. J Clin Microbiol (2005) 1.52
Test characteristics of urinary lipoarabinomannan and predictors of mortality among hospitalized HIV-infected tuberculosis suspects in Tanzania. PLoS One (2012) 1.26
Sputum microscopy for the diagnosis of HIV-associated pulmonary tuberculosis in Tanzania. BMC Public Health (2008) 1.14
Expansion and contraction of HIV-specific CD4 T cells with short bursts of viremia, but physical loss of the majority of these cells with sustained viral replication. J Immunol (2005) 1.08
Interferon γ responses to mycobacterial antigens protect against subsequent HIV-associated tuberculosis. J Infect Dis (2010) 1.00
Invasive Mycobacterium marinum infections. Emerg Infect Dis (2003) 0.99
Influenza, Winter Olympiad, 2002. Emerg Infect Dis (2006) 0.95
Patient attitudes to donation of embryos for research in Western Australia. Med J Aust (2004) 0.93
Death rounds: end-of-life discussions among medical residents in the intensive care unit. J Crit Care (2005) 0.91
Potential sperm donors', recipients' and their partners' opinions towards the release of identifying information in Western Australia. Hum Reprod (2006) 0.90
Intestinal immunity is a determinant of clearance of poliovirus after oral vaccination. J Infect Dis (2014) 0.90
Molecular epidemiology of HIV-associated tuberculosis in Dar es Salaam, Tanzania: strain predominance, clustering, and polyclonal disease. J Clin Microbiol (2012) 0.88
Questionable superiority of linezolid for methicillin-resistant Staphylococcus aureus nosocomial pneumonia: watch where you step. Clin Infect Dis (2012) 0.87
Specificity of the tuberculin skin test and the T-SPOT.TB assay among students in a low-tuberculosis incidence setting. J Am Coll Health (2012) 0.86
Polyantigenic interferon-γ responses are associated with protection from TB among HIV-infected adults with childhood BCG immunization. PLoS One (2011) 0.86
Baseline mycobacterial immune responses in HIV-infected adults primed with bacille Calmette-Guérin during childhood and entering a tuberculosis booster vaccine trial. J Infect Dis (2006) 0.81
Children's medicines in Tanzania: a national survey of administration practices and preferences. PLoS One (2013) 0.81
Living in rural New England amplifies the risk of depression in patients with HIV. BMC Infect Dis (2009) 0.79
Fatal hemoptysis from invasive Aspergillus niger in a patient with cavitary lung disease and Mycobacterium avium complex infection. Med Mycol (2006) 0.78
Glucocorticoid-induced tumor necrosis factor receptor family-related protein triggering enhances HIV-specific CD4+ T cell cytokine secretion and protects HIV-specific CD4+ T cells from apoptosis. J Infect Dis (2007) 0.78
Human seminal plasma fosters CD4(+) regulatory T-cell phenotype and transforming growth factor-β1 expression. Am J Reprod Immunol (2012) 0.77
Male age negatively influences clinical pregnancy rate in women younger than 40 years undergoing donor insemination cycles. Reprod Biomed Online (2013) 0.77
The design of a medical school social justice curriculum. Acad Med (2013) 0.77
Skin nodules and back pain. West J Med (2002) 0.75
Residents' work hours. Ann Intern Med (2004) 0.75
Post tenectplase angioplasty vs PAMI in ST elevation MI. (Pathak trial). Indian Heart J (2012) 0.75
Question: Can you identify this condition? Acute retinal necrosis. Can Fam Physician (2013) 0.75
Current administration practices and preferred formulations of children's medicines in Tanzania: summary of survey findings. Int J Pharm (2012) 0.75