Published in Cell Host Microbe on December 15, 2011
Repurposing Hsp104 to Antagonize Seminal Amyloid and Counter HIV Infection. Chem Biol (2015) 1.44
Naturally occurring fragments from two distinct regions of the prostatic acid phosphatase form amyloidogenic enhancers of HIV infection. J Virol (2011) 1.42
A Peptide Derived from the HIV-1 gp120 Coreceptor-Binding Region Promotes Formation of PAP248-286 Amyloid Fibrils to Enhance HIV-1 Infection. PLoS One (2015) 1.41
Peptide nanofibrils boost retroviral gene transfer and provide a rapid means for concentrating viruses. Nat Nanotechnol (2013) 1.12
Direct visualization of HIV-enhancing endogenous amyloid fibrils in human semen. Nat Commun (2014) 1.08
Bottlenecks in HIV-1 transmission: insights from the study of founder viruses. Nat Rev Microbiol (2015) 1.08
Interleukin-7 facilitates HIV-1 transmission to cervico-vaginal tissue ex vivo. PLoS Pathog (2013) 1.05
Identification and function of proteolysis regulators in seminal fluid. Mol Reprod Dev (2012) 1.02
Seminal plasma accelerates semen-derived enhancer of viral infection (SEVI) fibril formation by the prostatic acid phosphatase (PAP248-286) peptide. J Biol Chem (2012) 0.98
Effect of semen and seminal amyloid on vaginal transmission of simian immunodeficiency virus. Retrovirology (2013) 0.97
Seminal plasma induces global transcriptomic changes associated with cell migration, proliferation and viability in endometrial epithelial cells and stromal fibroblasts. Hum Reprod (2014) 0.97
Semen enhances HIV infectivity and impairs the antiviral efficacy of microbicides. Sci Transl Med (2014) 0.97
Nucleic acid-containing amyloid fibrils potently induce type I interferon and stimulate systemic autoimmunity. Proc Natl Acad Sci U S A (2012) 0.97
A novel role for APOBEC3: susceptibility to sexual transmission of murine acquired immunodeficiency virus (mAIDS) is aggravated in APOBEC3 deficient mice. Retrovirology (2012) 0.96
Bacterial curli protein promotes the conversion of PAP248-286 into the amyloid SEVI: cross-seeding of dissimilar amyloid sequences. PeerJ (2013) 0.93
Core sequence of PAPf39 amyloid fibrils and mechanism of pH-dependent fibril formation: the role of monomer conformation. Biochemistry (2012) 0.92
The Surprising Role of Amyloid Fibrils in HIV Infection. Biology (Basel) (2012) 0.91
Liquefaction of semen generates and later degrades a conserved semenogelin peptide that enhances HIV infection. J Virol (2014) 0.89
Innate and adaptive immune responses in male and female reproductive tracts in homeostasis and following HIV infection. Cell Mol Immunol (2014) 0.88
Polyanionic candidate microbicides accelerate the formation of semen-derived amyloid fibrils to enhance HIV-1 infection. PLoS One (2013) 0.86
Seminal plasma and semen amyloids enhance cytomegalovirus infection in cell culture. J Virol (2013) 0.86
A molecular tweezer antagonizes seminal amyloids and HIV infection. Elife (2015) 0.83
Fluorescence detection of cationic amyloid fibrils in human semen. Bioorg Med Chem Lett (2013) 0.82
Interaction of fibronectin with semen amyloids synergistically enhances HIV infection. J Infect Dis (2014) 0.82
HIV-1 vaginal transmission: cell-free or cell-associated virus? Am J Reprod Immunol (2014) 0.81
Semen-derived enhancer of viral infection (SEVI) binds bacteria, enhances bacterial phagocytosis by macrophages, and can protect against vaginal infection by a sexually transmitted bacterial pathogen. Antimicrob Agents Chemother (2013) 0.80
Sexual violence and HIV transmission: summary proceedings of a scientific research planning meeting. Am J Reprod Immunol (2012) 0.80
Structural characterization of semen coagulum-derived SEM1(86-107) amyloid fibrils that enhance HIV-1 infection. Biochemistry (2014) 0.79
Amyloid formation: functional friend or fearful foe? J Intern Med (2016) 0.78
Improving preclinical models of HIV microbicide efficacy. Trends Microbiol (2015) 0.78
Epigallocatechin-3-gallate rapidly remodels PAP85-120, SEM1(45-107), and SEM2(49-107) seminal amyloid fibrils. Biol Open (2015) 0.78
Blocking HIV-1 transmission in the female reproductive tract: from microbicide development to exploring local antiviral responses. Clin Transl Immunology (2015) 0.77
Zika virus preferentially replicates in the female reproductive tract after vaginal inoculation of rhesus macaques. PLoS Pathog (2017) 0.77
Semen amyloids participate in spermatozoa selection and clearance. Elife (2017) 0.76
No SEVI-mediated enhancement of rectal HIV-1 transmission of HIV-1 in two humanized mouse cohorts. Virology (2015) 0.76
Fertility defects in mice expressing the L68Q variant of human cystatin C: a role for amyloid in male infertility. J Biol Chem (2014) 0.76
Enhancement of herpes simplex virus (HSV) infection by seminal plasma and semen amyloids implicates a new target for the prevention of HSV infection. Viruses (2015) 0.76
Predominant Role of Plasmacytoid Dendritic Cells in Stimulating Systemic Autoimmunity. Front Immunol (2015) 0.76
Comparison of the effect of semen from HIV-infected and uninfected men on CD4+ T-cell infection. AIDS (2016) 0.75
Abolishing HIV-1 infectivity using a polypurine tract-specific G-quadruplex-forming oligonucleotide. BMC Infect Dis (2016) 0.75
Gallic Acid Is an Antagonist of Semen Amyloid Fibrils That Enhance HIV-1 Infection. J Biol Chem (2016) 0.75
HIV, sexual violence and special populations: adolescence and pregnancy. Am J Reprod Immunol (2012) 0.75
Mucosal stromal fibroblasts markedly enhance HIV infection of CD4+ T cells. PLoS Pathog (2017) 0.75
Epigallocatechin gallate inhibits macaque SEVI-mediated enhancement of SIV or SHIV infection. J Acquir Immune Defic Syndr (2017) 0.75
K114 (trans, trans)-bromo-2,5-bis(4-hydroxystyryl)benzene is an efficient detector of cationic amyloid fibrils. Protein Sci (2015) 0.75
Efficacy of HIV antiviral polyanionic carbosilane dendrimer G2-S16 in the presence of semen. Int J Nanomedicine (2016) 0.75
The KT Jeang Retrovirology prize 2016: Frank Kirchhoff. Retrovirology (2016) 0.75
Friend or Foe: Innate Sensing of HIV in the Female Reproductive Tract. Curr HIV/AIDS Rep (2016) 0.75
ADS-J1 inhibits semen-derived amyloid fibril formation and blocks fibril-mediated enhancement of HIV-1 infection. Antimicrob Agents Chemother (2015) 0.75
Inhibition of the enhancement of infection of human immunodeficiency virus by semen-derived enhancer of virus infection using amyloid-targeting polymeric nanoparticles. ACS Nano (2015) 0.75
Functional Amyloids in Reproduction. Biomolecules (2017) 0.75
A Degraded Fragment of HIV-1 Gp120 in Rat Hepatocytes Forms Fibrils and Enhances HIV-1 Infection. Biophys J (2017) 0.75
In Situ Investigation of Peptide-Lipid Interaction Between PAP248-286 and Model Cell Membranes. J Membr Biol (2016) 0.75
Lack of effectiveness of cellulose sulfate gel for the prevention of vaginal HIV transmission. N Engl J Med (2008) 6.00
A sensitive and specific enzyme-based assay detecting HIV-1 virion fusion in primary T lymphocytes. Nat Biotechnol (2002) 5.49
Semen-derived amyloid fibrils drastically enhance HIV infection. Cell (2007) 5.23
Fibril specific, conformation dependent antibodies recognize a generic epitope common to amyloid fibrils and fibrillar oligomers that is absent in prefibrillar oligomers. Mol Neurodegener (2007) 4.15
Intravaginal inoculation of rhesus macaques with cell-free simian immunodeficiency virus results in persistent or transient viremia. J Virol (1994) 3.05
Conformational Abs recognizing a generic amyloid fibril epitope. Proc Natl Acad Sci U S A (2002) 2.62
The cationic properties of SEVI underlie its ability to enhance human immunodeficiency virus infection. J Virol (2008) 2.38
Apoptotic neutrophils and T cells sequester chemokines during immune response resolution through modulation of CCR5 expression. Nat Immunol (2006) 2.37
The main green tea polyphenol epigallocatechin-3-gallate counteracts semen-mediated enhancement of HIV infection. Proc Natl Acad Sci U S A (2009) 1.77
Semen-mediated enhancement of HIV infection is donor-dependent and correlates with the levels of SEVI. Retrovirology (2010) 1.70
Amyloid structure: conformational diversity and consequences. Annu Rev Biochem (2011) 1.57
Nef enhances human immunodeficiency virus type 1 infectivity and replication independently of viral coreceptor tropism. J Virol (2002) 1.53
Aminoquinoline surfen inhibits the action of SEVI (semen-derived enhancer of viral infection). J Biol Chem (2009) 1.39
Cationic polypeptides contribute to the anti-HIV-1 activity of human seminal plasma. FASEB J (2009) 1.33
Amyloid-binding small molecules efficiently block SEVI (semen-derived enhancer of virus infection)- and semen-mediated enhancement of HIV-1 infection. J Biol Chem (2010) 1.26
Spermatozoa capture HIV-1 through heparan sulfate and efficiently transmit the virus to dendritic cells. J Exp Med (2009) 1.24
Human seminal plasma abrogates the capture and transmission of human immunodeficiency virus type 1 to CD4+ T cells mediated by DC-SIGN. J Virol (2007) 1.23
Semenogelin, the main protein of semen coagulum, inhibits human sperm capacitation by interfering with the superoxide anion generated during this process. J Androl (2001) 1.23
Ejaculatory duct obstruction in subfertile males: analysis of 87 patients. Fertil Steril (1991) 1.22
Semenogelin I: a coagulum forming, multifunctional seminal vesicle protein. Cell Mol Life Sci (1999) 1.22
Clomiphene citrate administration to normogonadotropic subfertile men: blood hormone changes and activation of acid phosphatase in seminal fluid. Int J Androl (1981) 1.20
Characterization of prostate-specific antigen proteolytic activity on its major physiological substrate, the sperm motility inhibitor precursor/semenogelin I. Biochemistry (1997) 1.19
Exploiting common targets in human fertilization and HIV infection: development of novel contraceptive microbicides. Hum Reprod Update (2005) 1.07
Opsonization of HIV-1 by semen complement enhances infection of human epithelial cells. J Immunol (2002) 1.06
The major bactericidal activity of human seminal plasma is zinc-dependent and derived from fragmentation of the semenogelins. J Immunol (2008) 1.05
Variation in virological parameters and antibody responses in macaques after atraumatic vaginal exposure to a pathogenic primary isolate of SIVmac251. Res Virol (1998) 1.02
Quantification of seminal plasma motility inhibitor/semenogelin in human seminal plasma. J Androl (2003) 0.98
Semen protects CD4+ target cells from HIV infection but promotes the preferential transmission of R5 tropic HIV. J Immunol (2010) 0.97
Semenogelin, the main protein of the human semen coagulum, regulates sperm function. Semin Thromb Hemost (2007) 0.97
Amyloid of the seminal vesicles. A distinctive and common localized form of senile amyloidosis. Am J Pathol (1983) 0.96
Sperm motility inhibitor from human seminal plasma: association with semen coagulum. Hum Reprod (1995) 0.93
Distribution and tissue expression of semenogelin I and II in man as demonstrated by in situ hybridization and immunocytochemistry. J Androl (1997) 0.90
Monoclonal antibodies, immunofluorometric assay, and detection of human semenogelin in male reproductive tract: no association with in vitro fertilizing capacity of sperm. Biol Reprod (2002) 0.88
Senile seminal vesicle amyloid is derived from semenogelin I. J Lab Clin Med (2005) 0.87
Characterization of a monoclonal antibody to a conserved epitope on human seminal vesicle-specific peptides: a novel probe/marker system for semen identification. Biol Reprod (1986) 0.85
The abundant 19-kilodalton protein associated with human sperm nuclei that is related to seminal plasma alpha-inhibins. Mol Reprod Dev (1993) 0.81
Bull sperm motility and membrane integrity in media varying in osmolality. J Dairy Sci (1998) 0.79
Sperm hyaluronidase activation by purified predominant and major basic human seminal coagulum proteins. Hum Reprod (1995) 0.78
Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo. Science (2005) 14.43
The challenge of finding a cure for HIV infection. Science (2009) 8.41
HIV-1 Vif blocks the antiviral activity of APOBEC3G by impairing both its translation and intracellular stability. Mol Cell (2003) 7.42
Shaping the nuclear action of NF-kappaB. Nat Rev Mol Cell Biol (2004) 6.88
Sulforhodamine 101 as a specific marker of astroglia in the neocortex in vivo. Nat Methods (2004) 6.59
Nanotubular highways for intercellular organelle transport. Science (2004) 6.04
A sensitive and specific enzyme-based assay detecting HIV-1 virion fusion in primary T lymphocytes. Nat Biotechnol (2002) 5.49
Retracted Cellular APOBEC3G restricts HIV-1 infection in resting CD4+ T cells. Nature (2005) 5.28
Semen-derived amyloid fibrils drastically enhance HIV infection. Cell (2007) 5.23
Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF-kappaB. EMBO J (2002) 4.91
Composition and three-dimensional architecture of the dengue virus replication and assembly sites. Cell Host Microbe (2009) 4.54
NF-kappaB p50 promotes HIV latency through HDAC recruitment and repression of transcriptional initiation. EMBO J (2005) 4.35
The APOBEC3 cytidine deaminases: an innate defensive network opposing exogenous retroviruses and endogenous retroelements. Annu Rev Immunol (2008) 4.27
Nef-mediated suppression of T cell activation was lost in a lentiviral lineage that gave rise to HIV-1. Cell (2006) 4.13
Nef proteins from simian immunodeficiency viruses are tetherin antagonists. Cell Host Microbe (2009) 4.11
HIV vaccine research: the way forward. Science (2008) 3.86
Neuronal or glial progeny: regional differences in radial glia fate. Neuron (2003) 3.68
Tetherin-driven adaptation of Vpu and Nef function and the evolution of pandemic and nonpandemic HIV-1 strains. Cell Host Microbe (2009) 3.58
NF-kappaB RelA phosphorylation regulates RelA acetylation. Mol Cell Biol (2005) 3.50
Abortive HIV infection mediates CD4 T cell depletion and inflammation in human lymphoid tissue. Cell (2010) 3.42
A role for glia in the progression of Rett's syndrome. Nature (2011) 3.18
HIV latency. Cold Spring Harb Perspect Med (2011) 2.90
IFI16 DNA sensor is required for death of lymphoid CD4 T cells abortively infected with HIV. Science (2013) 2.68
Evolutionary and functional analyses of the interaction between the myeloid restriction factor SAMHD1 and the lentiviral Vpx protein. Cell Host Microbe (2012) 2.66
Three-dimensional imaging of the unsectioned adult spinal cord to assess axon regeneration and glial responses after injury. Nat Med (2011) 2.65
Viscoelastic properties of individual glial cells and neurons in the CNS. Proc Natl Acad Sci U S A (2006) 2.64
Neurotransmitter-triggered transfer of exosomes mediates oligodendrocyte-neuron communication. PLoS Biol (2013) 2.61
High-molecular-mass APOBEC3G complexes restrict Alu retrotransposition. Proc Natl Acad Sci U S A (2006) 2.54
The proteomes of human parotid and submandibular/sublingual gland salivas collected as the ductal secretions. J Proteome Res (2008) 2.53
Progeny of Olig2-expressing progenitors in the gray and white matter of the adult mouse cerebral cortex. J Neurosci (2008) 2.49
Prostratin antagonizes HIV latency by activating NF-kappaB. J Biol Chem (2004) 2.47
Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation. Nature (2011) 2.46
Microglia: new roles for the synaptic stripper. Neuron (2013) 2.44
The CD16+ monocyte subset is more permissive to infection and preferentially harbors HIV-1 in vivo. J Immunol (2007) 2.41
Toward an AIDS vaccine: lessons from natural simian immunodeficiency virus infections of African nonhuman primate hosts. Nat Med (2009) 2.41
The cationic properties of SEVI underlie its ability to enhance human immunodeficiency virus infection. J Virol (2008) 2.38
Germination of dimorphic seeds of the desert annual halophyte Suaeda aralocaspica (Chenopodiaceae), a C4 plant without Kranz anatomy. Ann Bot (2008) 2.36
Quantification of the impact of land-use changes on ecosystem services: a case study in Pingbian County, China. Environ Monit Assess (2007) 2.34
Segregated expression of AMPA-type glutamate receptors and glutamate transporters defines distinct astrocyte populations in the mouse hippocampus. J Neurosci (2003) 2.29
United we stand, divided we fall: a meta-analysis of experiments on clonal integration and its relationship to invasiveness. Oecologia (2012) 2.27
Discovery and optimization of a natural HIV-1 entry inhibitor targeting the gp41 fusion peptide. Cell (2007) 2.22
Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine. Proc Natl Acad Sci U S A (2010) 2.15
Low levels of SIV infection in sooty mangabey central memory CD⁴⁺ T cells are associated with limited CCR5 expression. Nat Med (2011) 2.08
Physiological integration in an introduced, invasive plant increases its spread into experimental communities and modifies their structure. Am J Bot (2009) 2.07
Compensatory link between fusion and endocytosis of human immunodeficiency virus type 1 in human CD4 T lymphocytes. J Virol (2004) 2.06
Three-dimensional architecture and biogenesis of membrane structures associated with hepatitis C virus replication. PLoS Pathog (2012) 2.04
p53 induces NF-kappaB activation by an IkappaB kinase-independent mechanism involving phosphorylation of p65 by ribosomal S6 kinase 1. J Biol Chem (2004) 2.01
Fibrils of prostatic acid phosphatase fragments boost infections with XMRV (xenotropic murine leukemia virus-related virus), a human retrovirus associated with prostate cancer. J Virol (2009) 2.00
Apobec3 encodes Rfv3, a gene influencing neutralizing antibody control of retrovirus infection. Science (2008) 1.97
Kinetics of neutralizing antibodies in patients naturally infected by H5N1 virus. PLoS One (2010) 1.96
In vivo fate mapping and expression analysis reveals molecular hallmarks of prospectively isolated adult neural stem cells. Cell Stem Cell (2010) 1.95
Seroprevalence of anti-H5 antibody in rural Cambodia, 2007. J Clin Virol (2010) 1.94
Adaptation of rhizome connections in drylands: increasing tolerance of clones to wind erosion. Ann Bot (2008) 1.93
Guidelines for naming nonprimate APOBEC3 genes and proteins. J Virol (2008) 1.86
Clinicopathological significance of abnormalities in Gadd45 expression and its relationship to p53 in human pancreatic cancer. Clin Cancer Res (2002) 1.85
Sphingosylphosphorylcholine regulates keratin network architecture and visco-elastic properties of human cancer cells. Nat Cell Biol (2003) 1.84
Regulation of distinct biological activities of the NF-kappaB transcription factor complex by acetylation. J Mol Med (Berl) (2003) 1.79
Chronically CNS-injured adult sensory neurons gain regenerative competence upon a lesion of their peripheral axon. Curr Biol (2009) 1.79
Endogenous factors enhance HIV infection of tissue naive CD4 T cells by stimulating high molecular mass APOBEC3G complex formation. J Exp Med (2006) 1.77
Contribution of Vpu, Env, and Nef to CD4 down-modulation and resistance of human immunodeficiency virus type 1-infected T cells to superinfection. J Virol (2006) 1.77
Sustained induction of NF-kappa B is required for efficient expression of latent human immunodeficiency virus type 1. J Virol (2007) 1.74
In vivo imaging of intersynaptic vesicle exchange using VGLUT1 Venus knock-in mice. J Neurosci (2011) 1.73
Semen-mediated enhancement of HIV infection is donor-dependent and correlates with the levels of SEVI. Retrovirology (2010) 1.70
Newly synthesized APOBEC3G is incorporated into HIV virions, inhibited by HIV RNA, and subsequently activated by RNase H. PLoS Pathog (2007) 1.70
In vitro derived dendritic cells trans-infect CD4 T cells primarily with surface-bound HIV-1 virions. PLoS Pathog (2007) 1.70
NMDA receptors mediate neuron-to-glia signaling in mouse cortical astrocytes. J Neurosci (2006) 1.69
Distinct patterns of cytokine regulation of APOBEC3G expression and activity in primary lymphocytes, macrophages, and dendritic cells. J Biol Chem (2006) 1.68
An integrated overview of HIV-1 latency. Cell (2013) 1.68
Characterization of embryonic globin genes of the zebrafish. Dev Biol (2003) 1.65
Role of retroviral restriction factors in the interferon-α-mediated suppression of HIV-1 in vivo. Proc Natl Acad Sci U S A (2012) 1.65
Nef-mediated enhancement of virion infectivity and stimulation of viral replication are fundamental properties of primate lentiviruses. J Virol (2007) 1.58
Head-to-head coiled arrangement of the subunits of the animal fatty acid synthase. Chem Biol (2004) 1.57
Lack of the Kir4.1 channel subunit abolishes K+ buffering properties of astrocytes in the ventral respiratory group: impact on extracellular K+ regulation. J Neurophysiol (2005) 1.57
Metabolic coupling of dehydration and decarboxylation in the curacin A pathway: functional identification of a mechanistically diverse enzyme pair. J Am Chem Soc (2006) 1.55
A flow cytometry-based FRET assay to identify and analyse protein-protein interactions in living cells. PLoS One (2010) 1.54
Ancient origin of a deletion in human BST2/Tetherin that confers protection against viral zoonoses. Hum Mutat (2011) 1.54
The Association of Biomolecular Resource Facilities Proteomics Research Group 2006 study: relative protein quantitation. Mol Cell Proteomics (2007) 1.53
Nef enhances human immunodeficiency virus type 1 infectivity and replication independently of viral coreceptor tropism. J Virol (2002) 1.53
A trade-off between guerrilla and phalanx growth forms in Leymus secalinus under different nutrient supplies. Ann Bot (2006) 1.51
Extensively cross-reactive anti-HIV-1 neutralizing antibodies induced by gp140 immunization. Proc Natl Acad Sci U S A (2007) 1.50
Astroglial processes show spontaneous motility at active synaptic terminals in situ. Eur J Neurosci (2004) 1.49
Regulation of HIV-1 latency by T-cell activation. Cytokine (2007) 1.48
Human immunodeficiency virus type 1 Vpr induces DNA replication stress in vitro and in vivo. J Virol (2006) 1.47
Biomaterials: silk-like secretion from tarantula feet. Nature (2006) 1.47
Uptake mechanism of oppositely charged fluorescent nanoparticles in HeLa cells. Macromol Biosci (2008) 1.44
Coordinated variation in leaf and root traits across multiple spatial scales in Chinese semi-arid and arid ecosystems. New Phytol (2010) 1.43