Published in Emerg Med J on November 10, 2010
Acute abdominal pain and radiological pneumoperitoneum - always an indication for laparotomy? J Clin Med Res (2013) 0.78
Biological, clinical and population relevance of 95 loci for blood lipids. Nature (2010) 28.21
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet (2010) 17.89
Meta-analysis and imputation refines the association of 15q25 with smoking quantity. Nat Genet (2010) 8.55
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. Nat Genet (2010) 6.66
LDL-cholesterol concentrations: a genome-wide association study. Lancet (2008) 6.44
The CoLaus study: a population-based study to investigate the epidemiology and genetic determinants of cardiovascular risk factors and metabolic syndrome. BMC Cardiovasc Disord (2008) 5.33
Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations. PLoS Genet (2009) 4.97
The Population Reference Sample, POPRES: a resource for population, disease, and pharmacological genetics research. Am J Hum Genet (2008) 4.79
GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Science (2013) 4.71
Genetic variants influencing circulating lipid levels and risk of coronary artery disease. Arterioscler Thromb Vasc Biol (2010) 4.08
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet (2011) 3.40
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet (2013) 3.25
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet (2012) 3.21
Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. Nat Genet (2011) 3.18
Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile. Nat Genet (2011) 2.73
Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locus. Nature (2011) 2.59
Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways. Nat Genet (2012) 2.12
Genome-wide linkage and association analyses to identify genes influencing adiponectin levels: the GEMS Study. Obesity (Silver Spring) (2009) 2.07
Scores to predict major bleeding risk during oral anticoagulation therapy: a prospective validation study. Am J Med (2012) 1.81
Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. Nat Genet (2013) 1.72
A genome-wide association search for type 2 diabetes genes in African Americans. PLoS One (2012) 1.72
A genome-wide association study of early menopause and the combined impact of identified variants. Hum Mol Genet (2013) 1.50
Eligibility to treatment and economic effect of the implementation of the new U.S. or European Society of Hypertension/European Society of Cardiology hypertension guidelines. J Hypertens (2015) 1.40
Genetic and phenotypic architecture of metabolic syndrome-associated components in dyslipidemic and normolipidemic subjects: the GEMS Study. Atherosclerosis (2007) 1.36
Relation between atherogenic dyslipidemia and the Adult Treatment Program-III definition of metabolic syndrome (Genetic Epidemiology of Metabolic Syndrome Project). Am J Cardiol (2005) 1.32
Dose-dependent positive association between cigarette smoking, abdominal obesity and body fat: cross-sectional data from a population-based survey. BMC Public Health (2011) 1.32
The PsyCoLaus study: methodology and characteristics of the sample of a population-based survey on psychiatric disorders and their association with genetic and cardiovascular risk factors. BMC Psychiatry (2009) 1.29
Exendin-4 protects beta-cells from interleukin-1 beta-induced apoptosis by interfering with the c-Jun NH2-terminal kinase pathway. Diabetes (2008) 1.27
Up-regulation of macrophage migration inhibitory factor gene and protein expression in glial tumor cells during hypoxic and hypoglycemic stress indicates a critical role for angiogenesis in glioblastoma multiforme. Am J Pathol (2003) 1.27
Genome-wide meta-analysis for serum calcium identifies significantly associated SNPs near the calcium-sensing receptor (CASR) gene. PLoS Genet (2010) 1.25
Prevalence, awareness, treatment and control of high blood pressure in a Swiss city general population: the CoLaus study. Eur J Cardiovasc Prev Rehabil (2009) 1.22
Geriatric depression and vascular diseases: what are the links? J Affect Disord (2004) 1.20
ICER induced by hyperglycemia represses the expression of genes essential for insulin exocytosis. EMBO J (2006) 1.16
Lipoprotein distribution and biological variation of 24S- and 27-hydroxycholesterol in healthy volunteers. Atherosclerosis (2006) 1.12
Alcohol drinking and cardiovascular risk in a population with high mean alcohol consumption. Am J Cardiol (2008) 1.12
Elevated serum uric acid is associated with high circulating inflammatory cytokines in the population-based Colaus study. PLoS One (2011) 1.11
Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease. Am J Clin Nutr (2013) 1.08
[Towards a single society for specialists in family medicine and specialists in general internal medicine in Switzerland?]. Rev Med Suisse (2008) 1.08
Insulin-secreting beta-cell dysfunction induced by human lipoproteins. J Biol Chem (2003) 1.08
["The union has the power"!]. Rev Med Suisse (2008) 1.07
An angiotensin II- and NF-kappaB-dependent mechanism increases connexin 43 in murine arteries targeted by renin-dependent hypertension. Cardiovasc Res (2010) 1.05
Prevalence of obesity and abdominal obesity in the Lausanne population. BMC Public Health (2008) 1.05
Association between circulating cytokine levels, diabetes and insulin resistance in a population-based sample (CoLaus study). Clin Endocrinol (Oxf) (2013) 1.03
Glucose represses connexin36 in insulin-secreting cells. J Cell Sci (2005) 1.03
Methods for testing association between uncertain genotypes and quantitative traits. Biostatistics (2010) 1.02
The repressor element silencing transcription factor (REST)-mediated transcriptional repression requires the inhibition of Sp1. J Biol Chem (2004) 1.00
Multiple QTLs influencing triglyceride and HDL and total cholesterol levels identified in families with atherogenic dyslipidemia. J Lipid Res (2005) 1.00
The Lausanne cohort Lc65+: a population-based prospective study of the manifestations, determinants and outcomes of frailty. BMC Geriatr (2008) 0.99
Prevalence and factors associated with difficulty and intention to quit smoking in Switzerland. BMC Public Health (2011) 0.99
Critical role of the transcriptional repressor neuron-restrictive silencer factor in the specific control of connexin36 in insulin-producing cell lines. J Biol Chem (2003) 0.98
Interleukin-8 secretion by fibroblasts induced by low density lipoproteins is p38 MAPK-dependent and leads to cell spreading and wound closure. J Biol Chem (2005) 0.98
Assessment of the capacity to consent to treatment in patients admitted to acute medical wards. BMC Med Ethics (2009) 0.96
Serum uric acid and adiposity: deciphering causality using a bidirectional Mendelian randomization approach. PLoS One (2012) 0.94
HDLs protect pancreatic β-cells against ER stress by restoring protein folding and trafficking. Diabetes (2012) 0.93
Association between variants of the leptin receptor gene (LEPR) and overweight: a systematic review and an analysis of the CoLaus study. PLoS One (2011) 0.92
ICER-1gamma overexpression drives palmitate-mediated connexin36 down-regulation in insulin-secreting cells. J Biol Chem (2007) 0.92
Complexin I regulates glucose-induced secretion in pancreatic beta-cells. J Cell Sci (2004) 0.92
Sex difference and the role of leptin in the association between high-sensitivity C-reactive protein and adiposity in two different populations. Eur J Epidemiol (2012) 0.92
Risk of falls and major bleeds in patients on oral anticoagulation therapy. Am J Med (2012) 0.92
The scaffold protein IB1/JIP-1 is a critical mediator of cytokine-induced apoptosis in pancreatic beta cells. J Cell Sci (2003) 0.92
Distribution of plasma levels of adiponectin and leptin in an adult Caucasian population. Clin Endocrinol (Oxf) (2009) 0.91
Predictive accuracy and usefulness of calibration of the ESC SCORE in Switzerland. Eur J Cardiovasc Prev Rehabil (2008) 0.91
Not all inflammatory markers are linked to kidney function: results from a population-based study. Am J Nephrol (2012) 0.91
The inter-rater reliability of the Pulmonary Embolism Severity Index. Thromb Haemost (2010) 0.90
Hyperhomocysteinemia is independently associated with albuminuria in the population-based CoLaus study. BMC Public Health (2011) 0.90
Low compliance with dietary recommendations for food intake among adults. Clin Nutr (2012) 0.89
Opinions on tobacco control policies in Lausanne, Switzerland, 2003-2006. Prev Med (2010) 0.89
Impaired expression of the inducible cAMP early repressor accounts for sustained adipose CREB activity in obesity. Diabetes (2011) 0.89
Population and economic impact of the 2013 ACC/AHA guidelines compared with European guidelines to prevent cardiovascular disease. Eur Heart J (2014) 0.88
Prevalence, treatment and control of dyslipidaemia in Switzerland: still a long way to go. Eur J Cardiovasc Prev Rehabil (2010) 0.88
Association between inflammatory and obesity markers in a Swiss population-based sample (CoLaus Study). Obes Facts (2012) 0.88
Increased connexin43 expression in human saphenous veins in culture is associated with intimal hyperplasia. J Vasc Surg (2005) 0.88
Predictive accuracy of original and recalibrated Framingham risk score in the Swiss population. Int J Cardiol (2008) 0.88
Ambulatory blood pressure monitoring: a mean to stratify cardiovascular risk. Blood Press Monit (2007) 0.88
Adipocytokines, hepatic and inflammatory biomarkers and incidence of type 2 diabetes. the CoLaus study. PLoS One (2012) 0.88
IB1/JIP-1 controls JNK activation and increased during prostatic LNCaP cells neuroendocrine differentiation. Cell Signal (2005) 0.87
Levels and determinants of inflammatory biomarkers in a Swiss population-based sample (CoLaus study). PLoS One (2011) 0.87
Genome-wide association study identifies two loci strongly affecting transferrin glycosylation. Hum Mol Genet (2011) 0.87
No interaction between alcohol consumption and HDL-related genes on HDL cholesterol levels. Atherosclerosis (2010) 0.87
Insulin modulation of luteinizing hormone secretion in normal female volunteers and lean polycystic ovary syndrome patients. Neuroendocrinology (2008) 0.86
Identification and validation of copy number variants using SNP genotyping arrays from a large clinical cohort. BMC Genomics (2012) 0.86
Prevalence of overweight and obesity among migrants in Switzerland: association with country of origin. Public Health Nutr (2011) 0.86
Association of statins with inflammatory cytokines: a population-based Colaus study. Atherosclerosis (2011) 0.86
Antihypertensive drug treatment changes in the general population: the CoLaus study. BMC Pharmacol Toxicol (2014) 0.86
No interactions between previously associated 2-hour glucose gene variants and physical activity or BMI on 2-hour glucose levels. Diabetes (2012) 0.86
The scaffold protein IB1/JIP-1 controls the activation of JNK in rat stressed urothelium. J Cell Sci (2002) 0.85
Cholesterol is the major component of native lipoproteins activating the p38 mitogen-activated protein kinases. Biol Chem (2005) 0.85
Connexin-36 contributes to control function of insulin-producing cells. J Biol Chem (2003) 0.85
Neuronal traits are required for glucose-induced insulin secretion. FEBS Lett (2004) 0.85
Prevalence of normal weight obesity in Switzerland: effect of various definitions. Eur J Nutr (2008) 0.85
Determinants and burden of chronic kidney disease in the population-based CoLaus study: a cross-sectional analysis. Nephrol Dial Transplant (2013) 0.84
Estimating the risk of developing type 2 diabetes: a comparison of several risk scores: the Cohorte Lausannoise study. Diabetes Care (2011) 0.84
Neurotensin is a regulator of insulin secretion in pancreatic beta-cells. Int J Biochem Cell Biol (2010) 0.83
Serum insulin and inflammatory markers in overweight individuals with and without dyslipidemia. J Clin Endocrinol Metab (2007) 0.83
Role of the JNK-interacting protein 1/islet brain 1 in cell degeneration in Alzheimer disease and diabetes. Brain Res Bull (2009) 0.83
[Statin prescription in primary prevention: which cardiovascular risk score should be used in Switzerland?]. Rev Med Suisse (2010) 0.83
Surrogate markers for atherosclerosis in overweight subjects with atherogenic dyslipidemia: the GEMS project. Angiology (2008) 0.82
Serum calcium levels are associated with novel cardiometabolic risk factors in the population-based CoLaus study. PLoS One (2011) 0.82
Expression of an uncleavable N-terminal RasGAP fragment in insulin-secreting cells increases their resistance toward apoptotic stimuli without affecting their glucose-induced insulin secretion. J Biol Chem (2005) 0.82