Published in J Biol Chem on November 04, 2004
Alterations in microRNA expression contribute to fatty acid-induced pancreatic beta-cell dysfunction. Diabetes (2008) 1.85
Involvement of microRNAs in the cytotoxic effects exerted by proinflammatory cytokines on pancreatic beta-cells. Diabetes (2010) 1.80
Retracted Modulation of CD59 expression by restrictive silencer factor-derived peptides in cancer immunotherapy for neuroblastoma. Cancer Res (2008) 1.49
ICER induced by hyperglycemia represses the expression of genes essential for insulin exocytosis. EMBO J (2006) 1.16
Transcriptional control of KCNQ channel genes and the regulation of neuronal excitability. J Neurosci (2010) 1.07
Evidence of the neuron-restrictive silencer factor (NRSF) interaction with Sp3 and its synergic repression to the mu opioid receptor (MOR) gene. Nucleic Acids Res (2006) 1.04
Interaction among variant vascular endothelial growth factor (VEGF) and its receptor in relation to prostate cancer risk. Prostate (2010) 1.02
Specificity protein 1 (Sp1)-dependent activation of the synapsin I gene (SYN1) is modulated by RE1-silencing transcription factor (REST) and 5'-cytosine-phosphoguanine (CpG) methylation. J Biol Chem (2012) 0.86
The GTPase Rab37 Participates in the Control of Insulin Exocytosis. PLoS One (2013) 0.85
The GTPase RalA regulates different steps of the secretory process in pancreatic beta-cells. PLoS One (2009) 0.81
Comparative genomics of neuroglobin reveals its early origins. PLoS One (2012) 0.79
Regulation of mGluR1 expression in human melanocytes and melanoma cells. Biochim Biophys Acta (2012) 0.76
Discovery and validation of information theory-based transcription factor and cofactor binding site motifs. Nucleic Acids Res (2016) 0.75
Regulation of GTP-binding protein (Gαs) expression in human myometrial cells: a role for tumor necrosis factor in modulating Gαs promoter acetylation by transcriptional complexes. J Biol Chem (2013) 0.75
Biological, clinical and population relevance of 95 loci for blood lipids. Nature (2010) 28.21
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet (2010) 17.89
Meta-analysis and imputation refines the association of 15q25 with smoking quantity. Nat Genet (2010) 8.55
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. Nat Genet (2010) 6.66
LDL-cholesterol concentrations: a genome-wide association study. Lancet (2008) 6.44
The CoLaus study: a population-based study to investigate the epidemiology and genetic determinants of cardiovascular risk factors and metabolic syndrome. BMC Cardiovasc Disord (2008) 5.33
Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations. PLoS Genet (2009) 4.97
The Population Reference Sample, POPRES: a resource for population, disease, and pharmacological genetics research. Am J Hum Genet (2008) 4.79
GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Science (2013) 4.71
Genetic variants influencing circulating lipid levels and risk of coronary artery disease. Arterioscler Thromb Vasc Biol (2010) 4.08
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet (2011) 3.40
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet (2013) 3.25
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet (2012) 3.21
Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. Nat Genet (2011) 3.18
Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile. Nat Genet (2011) 2.73
Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locus. Nature (2011) 2.59
MicroRNA-9 controls the expression of Granuphilin/Slp4 and the secretory response of insulin-producing cells. J Biol Chem (2006) 2.29
Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways. Nat Genet (2012) 2.12
Genome-wide linkage and association analyses to identify genes influencing adiponectin levels: the GEMS Study. Obesity (Silver Spring) (2009) 2.07
Alterations in microRNA expression contribute to fatty acid-induced pancreatic beta-cell dysfunction. Diabetes (2008) 1.85
Fibrinogen and fibronectin binding cooperate for valve infection and invasion in Staphylococcus aureus experimental endocarditis. J Exp Med (2005) 1.85
Scores to predict major bleeding risk during oral anticoagulation therapy: a prospective validation study. Am J Med (2012) 1.81
Involvement of microRNAs in the cytotoxic effects exerted by proinflammatory cytokines on pancreatic beta-cells. Diabetes (2010) 1.80
Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. Nat Genet (2013) 1.72
A genome-wide association search for type 2 diabetes genes in African Americans. PLoS One (2012) 1.72
High risk for hyperlipidemia and the metabolic syndrome after an episode of hypertriglyceridemia during 13-cis retinoic acid therapy for acne: a pharmacogenetic study. Ann Intern Med (2002) 1.58
A genome-wide association study of early menopause and the combined impact of identified variants. Hum Mol Genet (2013) 1.50
Release of macrophage migration inhibitory factor by neuroendocrine-differentiated LNCaP cells sustains the proliferation and survival of prostate cancer cells. Endocr Relat Cancer (2013) 1.49
Restoration of connexin 40 (Cx40) in Renin-producing cells reduces the hypertension of Cx40 null mice. Hypertension (2014) 1.44
Eligibility to treatment and economic effect of the implementation of the new U.S. or European Society of Hypertension/European Society of Cardiology hypertension guidelines. J Hypertens (2015) 1.40
Sepsis up-regulates the expression of connexin 40 in rat aortic endothelium. Crit Care Med (2005) 1.40
Role of Connexins and Pannexins in the Pancreas. Pancreas (2015) 1.39
Genetic and phenotypic architecture of metabolic syndrome-associated components in dyslipidemic and normolipidemic subjects: the GEMS Study. Atherosclerosis (2007) 1.36
Relation between atherogenic dyslipidemia and the Adult Treatment Program-III definition of metabolic syndrome (Genetic Epidemiology of Metabolic Syndrome Project). Am J Cardiol (2005) 1.32
Dose-dependent positive association between cigarette smoking, abdominal obesity and body fat: cross-sectional data from a population-based survey. BMC Public Health (2011) 1.32
The PsyCoLaus study: methodology and characteristics of the sample of a population-based survey on psychiatric disorders and their association with genetic and cardiovascular risk factors. BMC Psychiatry (2009) 1.29
Exendin-4 protects beta-cells from interleukin-1 beta-induced apoptosis by interfering with the c-Jun NH2-terminal kinase pathway. Diabetes (2008) 1.27
Up-regulation of macrophage migration inhibitory factor gene and protein expression in glial tumor cells during hypoxic and hypoglycemic stress indicates a critical role for angiogenesis in glioblastoma multiforme. Am J Pathol (2003) 1.27
Genome-wide meta-analysis for serum calcium identifies significantly associated SNPs near the calcium-sensing receptor (CASR) gene. PLoS Genet (2010) 1.25
Prevalence, awareness, treatment and control of high blood pressure in a Swiss city general population: the CoLaus study. Eur J Cardiovasc Prev Rehabil (2009) 1.22
Geriatric depression and vascular diseases: what are the links? J Affect Disord (2004) 1.20
MicroRNAs contribute to compensatory β cell expansion during pregnancy and obesity. J Clin Invest (2012) 1.17
ICER induced by hyperglycemia represses the expression of genes essential for insulin exocytosis. EMBO J (2006) 1.16
Connexins: key mediators of endocrine function. Physiol Rev (2011) 1.16
Alcohol drinking and cardiovascular risk in a population with high mean alcohol consumption. Am J Cardiol (2008) 1.12
Lipoprotein distribution and biological variation of 24S- and 27-hydroxycholesterol in healthy volunteers. Atherosclerosis (2006) 1.12
Elevated serum uric acid is associated with high circulating inflammatory cytokines in the population-based Colaus study. PLoS One (2011) 1.11
Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease. Am J Clin Nutr (2013) 1.08
Connexins protect mouse pancreatic β cells against apoptosis. J Clin Invest (2011) 1.08
[Towards a single society for specialists in family medicine and specialists in general internal medicine in Switzerland?]. Rev Med Suisse (2008) 1.08
Insulin-secreting beta-cell dysfunction induced by human lipoproteins. J Biol Chem (2003) 1.08
["The union has the power"!]. Rev Med Suisse (2008) 1.07
An angiotensin II- and NF-kappaB-dependent mechanism increases connexin 43 in murine arteries targeted by renin-dependent hypertension. Cardiovasc Res (2010) 1.05
Prevalence of obesity and abdominal obesity in the Lausanne population. BMC Public Health (2008) 1.05
Loss of connexin40 is associated with decreased endothelium-dependent relaxations and eNOS levels in the mouse aorta. Am J Physiol Heart Circ Physiol (2010) 1.04
Glucose represses connexin36 in insulin-secreting cells. J Cell Sci (2005) 1.03
Association between circulating cytokine levels, diabetes and insulin resistance in a population-based sample (CoLaus study). Clin Endocrinol (Oxf) (2013) 1.03
Methods for testing association between uncertain genotypes and quantitative traits. Biostatistics (2010) 1.02
GLUT8 is dispensable for embryonic development but influences hippocampal neurogenesis and heart function. Mol Cell Biol (2006) 1.02
Multiple QTLs influencing triglyceride and HDL and total cholesterol levels identified in families with atherogenic dyslipidemia. J Lipid Res (2005) 1.00
The Lausanne cohort Lc65+: a population-based prospective study of the manifestations, determinants and outcomes of frailty. BMC Geriatr (2008) 0.99
Prevalence and factors associated with difficulty and intention to quit smoking in Switzerland. BMC Public Health (2011) 0.99
Critical role of the transcriptional repressor neuron-restrictive silencer factor in the specific control of connexin36 in insulin-producing cell lines. J Biol Chem (2003) 0.98
Interleukin-8 secretion by fibroblasts induced by low density lipoproteins is p38 MAPK-dependent and leads to cell spreading and wound closure. J Biol Chem (2005) 0.98
Assessment of the capacity to consent to treatment in patients admitted to acute medical wards. BMC Med Ethics (2009) 0.96
A unique set of SH3-SH3 interactions controls IB1 homodimerization. EMBO J (2006) 0.95
Serum uric acid and adiposity: deciphering causality using a bidirectional Mendelian randomization approach. PLoS One (2012) 0.94
Acute inflammation decreases the expression of connexin 40 in mouse lung. Shock (2007) 0.94
Role of hemodynamic forces in the ex vivo arterialization of human saphenous veins. J Vasc Surg (2013) 0.93
HDLs protect pancreatic β-cells against ER stress by restoring protein folding and trafficking. Diabetes (2012) 0.93
Association between variants of the leptin receptor gene (LEPR) and overweight: a systematic review and an analysis of the CoLaus study. PLoS One (2011) 0.92
ICER-1gamma overexpression drives palmitate-mediated connexin36 down-regulation in insulin-secreting cells. J Biol Chem (2007) 0.92
Complexin I regulates glucose-induced secretion in pancreatic beta-cells. J Cell Sci (2004) 0.92
Risk of falls and major bleeds in patients on oral anticoagulation therapy. Am J Med (2012) 0.92
Sex difference and the role of leptin in the association between high-sensitivity C-reactive protein and adiposity in two different populations. Eur J Epidemiol (2012) 0.92
The scaffold protein IB1/JIP-1 is a critical mediator of cytokine-induced apoptosis in pancreatic beta cells. J Cell Sci (2003) 0.92
Predictive accuracy and usefulness of calibration of the ESC SCORE in Switzerland. Eur J Cardiovasc Prev Rehabil (2008) 0.91
Distribution of plasma levels of adiponectin and leptin in an adult Caucasian population. Clin Endocrinol (Oxf) (2009) 0.91
Not all inflammatory markers are linked to kidney function: results from a population-based study. Am J Nephrol (2012) 0.91
The inter-rater reliability of the Pulmonary Embolism Severity Index. Thromb Haemost (2010) 0.90
Hyperhomocysteinemia is independently associated with albuminuria in the population-based CoLaus study. BMC Public Health (2011) 0.90
Low compliance with dietary recommendations for food intake among adults. Clin Nutr (2012) 0.89
Impaired expression of the inducible cAMP early repressor accounts for sustained adipose CREB activity in obesity. Diabetes (2011) 0.89
Non-surgical pneumoperitoneum. Emerg Med J (2010) 0.89
Opinions on tobacco control policies in Lausanne, Switzerland, 2003-2006. Prev Med (2010) 0.89
Connexins, diabetes and the metabolic syndrome. Curr Protein Pept Sci (2009) 0.89