Published in PLoS Genet on November 11, 2010
Whole-genome sequencing of multiple Arabidopsis thaliana populations. Nat Genet (2011) 6.59
An efficient multi-locus mixed-model approach for genome-wide association studies in structured populations. Nat Genet (2012) 3.03
Genome-wide patterns of genetic variation in worldwide Arabidopsis thaliana accessions from the RegMap panel. Nat Genet (2012) 2.78
Association mapping of local climate-sensitive quantitative trait loci in Arabidopsis thaliana. Proc Natl Acad Sci U S A (2010) 2.51
Ecological genomics of local adaptation. Nat Rev Genet (2013) 2.20
The advantages and limitations of trait analysis with GWAS: a review. Plant Methods (2013) 2.08
Natural variation in Arabidopsis: from molecular genetics to ecological genomics. Plant Physiol (2011) 2.06
Towards identifying genes underlying ecologically relevant traits in Arabidopsis thaliana. Nat Rev Genet (2010) 1.91
Plant salt-tolerance mechanisms. Trends Plant Sci (2014) 1.76
Genome-wide association mapping identifies a new arsenate reductase enzyme critical for limiting arsenic accumulation in plants. PLoS Biol (2014) 1.74
Genetic architecture of regulatory variation in Arabidopsis thaliana. Genome Res (2011) 1.32
ROS-mediated vascular homeostatic control of root-to-shoot soil Na delivery in Arabidopsis. EMBO J (2012) 1.29
Carotenoid cleavage dioxygenase4 is a negative regulator of β-carotene content in Arabidopsis seeds. Plant Cell (2013) 1.27
Polyploids exhibit higher potassium uptake and salinity tolerance in Arabidopsis. Science (2013) 1.27
A genome-wide association study identifies variants underlying the Arabidopsis thaliana shade avoidance response. PLoS Genet (2012) 1.18
GWAPP: a web application for genome-wide association mapping in Arabidopsis. Plant Cell (2012) 1.17
Genome-wide association studies identify heavy metal ATPase3 as the primary determinant of natural variation in leaf cadmium in Arabidopsis thaliana. PLoS Genet (2012) 1.16
Life at the extreme: lessons from the genome. Genome Biol (2012) 1.14
Genome-Wide Association Mapping of Fertility Reduction upon Heat Stress Reveals Developmental Stage-Specific QTLs in Arabidopsis thaliana. Plant Cell (2015) 1.13
Genomic diversity in switchgrass (Panicum virgatum): from the continental scale to a dune landscape. Mol Ecol (2011) 1.11
Mapping salinity tolerance during Arabidopsis thaliana germination and seedling growth. PLoS One (2011) 1.10
Biodiversity of mineral nutrient and trace element accumulation in Arabidopsis thaliana. PLoS One (2012) 1.09
A Scalable Open-Source Pipeline for Large-Scale Root Phenotyping of Arabidopsis. Plant Cell (2014) 1.08
Lagging adaptation to warming climate in Arabidopsis thaliana. Proc Natl Acad Sci U S A (2014) 1.07
Chromatin changes in response to drought, salinity, heat, and cold stresses in plants. Front Plant Sci (2015) 1.02
Natural CMT2 variation is associated with genome-wide methylation changes and temperature seasonality. PLoS Genet (2014) 1.00
Natural genetic variation of root system architecture from Arabidopsis to Brachypodium: towards adaptive value. Philos Trans R Soc Lond B Biol Sci (2012) 1.00
Combining genome-wide methods to investigate the genetic complexity of courtship song variation in Drosophila melanogaster. Mol Biol Evol (2013) 0.99
Longitudinal trends in climate drive flowering time clines in North American Arabidopsis thaliana. Ecol Evol (2012) 0.96
Environmentally responsive genome-wide accumulation of de novo Arabidopsis thaliana mutations and epimutations. Genome Res (2014) 0.95
Plant High-Affinity Potassium (HKT) Transporters involved in salinity tolerance: structural insights to probe differences in ion selectivity. Int J Mol Sci (2013) 0.94
Molecular mechanisms of regulation of sulfate assimilation: first steps on a long road. Front Plant Sci (2014) 0.89
Variation in sulfur and selenium accumulation is controlled by naturally occurring isoforms of the key sulfur assimilation enzyme ADENOSINE 5'-PHOSPHOSULFATE REDUCTASE2 across the Arabidopsis species range. Plant Physiol (2014) 0.89
Integration of Experiments across Diverse Environments Identifies the Genetic Determinants of Variation in Sorghum bicolor Seed Element Composition. Plant Physiol (2016) 0.88
Extensive cis-regulatory variation robust to environmental perturbation in Arabidopsis. Plant Cell (2014) 0.88
Biomass for thermochemical conversion: targets and challenges. Front Plant Sci (2013) 0.88
AtHKT1;1 mediates nernstian sodium channel transport properties in Arabidopsis root stelar cells. PLoS One (2011) 0.87
Elemental concentrations in the seed of mutants and natural variants of Arabidopsis thaliana grown under varying soil conditions. PLoS One (2013) 0.87
Genome-wide association mapping of growth dynamics detects time-specific and general quantitative trait loci. J Exp Bot (2015) 0.86
Natural variation of root traits: from development to nutrient uptake. Plant Physiol (2014) 0.86
Towards the identification of the loci of adaptive evolution. Methods Ecol Evol (2015) 0.85
Allelic heterogeneity and trade-off shape natural variation for response to soil micronutrient. PLoS Genet (2012) 0.85
RNA-seq analysis of the response of the halophyte, Mesembryanthemum crystallinum (ice plant) to high salinity. PLoS One (2015) 0.84
The ecological genomic basis of salinity adaptation in Tunisian Medicago truncatula. BMC Genomics (2014) 0.83
Genetic architecture of plant stress resistance: multi-trait genome-wide association mapping. New Phytol (2016) 0.83
Constitutive Expression of Rice MicroRNA528 Alters Plant Development and Enhances Tolerance to Salinity Stress and Nitrogen Starvation in Creeping Bentgrass. Plant Physiol (2015) 0.83
Grand challenges in plant nutrition. Front Plant Sci (2011) 0.81
The Multi-allelic Genetic Architecture of a Variance-Heterogeneity Locus for Molybdenum Concentration in Leaves Acts as a Source of Unexplained Additive Genetic Variance. PLoS Genet (2015) 0.80
Genetic Regulation of Transcriptional Variation in Natural Arabidopsis thaliana Accessions. G3 (Bethesda) (2016) 0.79
Effect of salt stress on growth, Na+ accumulation and proline metabolism in potato (Solanum tuberosum) cultivars. PLoS One (2013) 0.79
Increasing cyclic electron flow is related to Na+ sequestration into vacuoles for salt tolerance in soybean. J Exp Bot (2015) 0.78
Salt tolerance during germination and seedling growth of wild wheat Aegilops tauschii and its impact on the species range expansion. Sci Rep (2016) 0.78
Mapping of ionomic traits in Mimulus guttatus reveals Mo and Cd QTLs that colocalize with MOT1 homologues. PLoS One (2012) 0.78
Modulation of R-gene expression across environments. J Exp Bot (2016) 0.78
Salinity Is an Agent of Divergent Selection Driving Local Adaptation of Arabidopsis to Coastal Habitats. Plant Physiol (2015) 0.78
Effect of salt stress on ion concentration, proline content, antioxidant enzyme activities and gene expression in tomato cultivars. AoB Plants (2016) 0.78
Genome Wide Association Mapping for the Tolerance to the Polyamine Oxidase Inhibitor Guazatine in Arabidopsis thaliana. Front Plant Sci (2016) 0.77
Novel Genes Affecting the Interaction between the Cabbage Whitefly and Arabidopsis Uncovered by Genome-Wide Association Mapping. PLoS One (2015) 0.77
The role of organelle genomes in plant adaptation: time to get to work! Plant Signal Behav (2011) 0.77
Beyond QTL cloning. PLoS Genet (2010) 0.77
Natural variation in non-coding regions underlying phenotypic diversity in budding yeast. Sci Rep (2016) 0.77
Natural genetic variation in Arabidopsis for responsiveness to plant growth-promoting rhizobacteria. Plant Mol Biol (2016) 0.76
Assessment of natural variation in the first pore domain of the tomato HKT1;2 transporter and characterization of mutated versions of SlHKT1;2 expressed in Xenopus laevis oocytes and via complementation of the salt sensitive athkt1;1 mutant. Front Plant Sci (2014) 0.76
ZEAXANTHIN EPOXIDASE Activity Potentiates Carotenoid Degradation in Maturing Seed. Plant Physiol (2016) 0.76
Natural variation in rosette size under salt stress conditions corresponds to developmental differences between Arabidopsis accessions and allelic variation in the LRR-KISS gene. J Exp Bot (2016) 0.76
Arabidopsis sos1 mutant in a salt-tolerant accession revealed an importance of salt acclimation ability in plant salt tolerance. Plant Signal Behav (2013) 0.76
Automated video tracking of thrips behavior to assess host-plant resistance in multiple parallel two-choice setups. Plant Methods (2016) 0.76
Potassium Retention under Salt Stress Is Associated with Natural Variation in Salinity Tolerance among Arabidopsis Accessions. PLoS One (2015) 0.76
AtWRKY22 promotes susceptibility to aphids and modulates salicylic acid and jasmonic acid signalling. J Exp Bot (2016) 0.76
Salt intolerance in Arabidopsis: shoot and root sodium toxicity, and inhibition by sodium-plus-potassium overaccumulation. Planta (2015) 0.76
Natural Genetic Variation of Seed Micronutrients of Arabidopsis thaliana Grown in Zinc-Deficient and Zinc-Amended Soil. Front Plant Sci (2016) 0.75
Demographic History, Population Structure, and Local Adaptation in Alpine Populations of Cardamine impatiens and Cardamine resedifolia. PLoS One (2015) 0.75
GWA Mapping of Anthocyanin Accumulation Reveals Balancing Selection of MYB90 in Arabidopsis thaliana. PLoS One (2015) 0.75
Bayesian model comparison in genetic association analysis: linear mixed modeling and SNP set testing. Biostatistics (2015) 0.75
Grand challenge: viewing transporter function in a pointillist landscape. Front Plant Sci (2011) 0.75
Re-Evaluation of Reportedly Metal Tolerant Arabidopsis thaliana Accessions. PLoS One (2016) 0.75
Genome-wide association analysis reveals distinct genetic architectures for single and combined stress responses in Arabidopsis thaliana. New Phytol (2016) 0.75
Genome-Wide Association Analysis of Adaptation Using Environmentally Predicted Traits. PLoS Genet (2015) 0.75
Cryptic Genetic Variation for Arabidopsis thaliana Seed Germination Speed in a Novel Salt Stress Environment. G3 (Bethesda) (2016) 0.75
Bioinformatics Approach in Plant Genomic Research. Curr Genomics (2016) 0.75
Multilevel Regulation of Abiotic Stress Responses in Plants. Front Plant Sci (2017) 0.75
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods (2001) 414.27
The detection of disease clustering and a generalized regression approach. Cancer Res (1967) 39.90
A unified mixed-model method for association mapping that accounts for multiple levels of relatedness. Nat Genet (2005) 20.97
Mechanisms of salinity tolerance. Annu Rev Plant Biol (2008) 14.34
Genome-wide association study of 107 phenotypes in Arabidopsis thaliana inbred lines. Nature (2010) 10.66
Genomic scale profiling of nutrient and trace elements in Arabidopsis thaliana. Nat Biotechnol (2003) 4.20
The scale of population structure in Arabidopsis thaliana. PLoS Genet (2010) 3.12
Genetic mechanisms and evolutionary significance of natural variation in Arabidopsis. Nature (2006) 3.00
What has natural variation taught us about plant development, physiology, and adaptation? Plant Cell (2009) 2.94
Natural variants of AtHKT1 enhance Na+ accumulation in two wild populations of Arabidopsis. PLoS Genet (2006) 2.91
Effects of genetic perturbation on seasonal life history plasticity. Science (2009) 2.61
Functional analysis of AtHKT1 in Arabidopsis shows that Na(+) recirculation by the phloem is crucial for salt tolerance. EMBO J (2003) 2.42
Shoot Na+ exclusion and increased salinity tolerance engineered by cell type-specific alteration of Na+ transport in Arabidopsis. Plant Cell (2009) 2.37
Evolutionary and functional insights into the mechanism underlying high-altitude adaptation of deer mouse hemoglobin. Proc Natl Acad Sci U S A (2009) 2.32
Altered shoot/root Na+ distribution and bifurcating salt sensitivity in Arabidopsis by genetic disruption of the Na+ transporter AtHKT1. FEBS Lett (2002) 1.99
Natural selection for salt tolerance quantitative trait loci (QTLs) in wild sunflower hybrids: implications for the origin of Helianthus paradoxus, a diploid hybrid species. Mol Ecol (2003) 1.93
The origin of ecological divergence in Helianthus paradoxus (Asteraceae): selection on transgressive characters in a novel hybrid habitat. Evolution (2003) 1.90
Purdue ionomics information management system. An integrated functional genomics platform. Plant Physiol (2006) 1.77
Identification of a candidate adaptive polymorphism for Drosophila life history by parallel independent clines on two continents. Mol Ecol (2010) 1.66
A clinally varying promoter polymorphism associated with adaptive variation in wing size in Drosophila. Mol Ecol (2010) 1.55
HKT transporter-mediated salinity resistance mechanisms in Arabidopsis and monocot crop plants. Trends Plant Sci (2009) 1.52
Ecological reproductive isolation of coast and inland races of Mimulus guttatus. Evolution (2008) 1.48
Genetic and physiological basis of adaptive salt tolerance divergence between coastal and inland Mimulus guttatus. New Phytol (2009) 1.32
Habitat divergence between a homoploid hybrid sunflower species, Helianthus paradoxus (Asteraceae), and its progenitors. Am J Bot (2002) 1.22
Candidate gene polymorphisms associated with salt tolerance in wild sunflower hybrids: implications for the origin of Helianthus paradoxus, a diploid hybrid species. New Phytol (2004) 1.07
Microsatellite signature of ecological selection for salt tolerance in a wild sunflower hybrid species, Helianthus paradoxus. Mol Ecol (2006) 0.95
Response to salinity in the homoploid hybrid species Helianthus paradoxus and its progenitors H. annuus and H. petiolaris. New Phytol (2006) 0.92
Topological domains in mammalian genomes identified by analysis of chromatin interactions. Nature (2012) 18.23
The Genome sequence of the SARS-associated coronavirus. Science (2003) 16.68
Scope and impact of financial conflicts of interest in biomedical research: a systematic review. JAMA (2003) 16.08
Genome-wide association study of 107 phenotypes in Arabidopsis thaliana inbred lines. Nature (2010) 10.66
Aberrant innate immune response in lethal infection of macaques with the 1918 influenza virus. Nature (2007) 10.40
The pattern of polymorphism in Arabidopsis thaliana. PLoS Biol (2005) 10.13
Common sequence polymorphisms shaping genetic diversity in Arabidopsis thaliana. Science (2007) 9.85
Modelling schizophrenia using human induced pluripotent stem cells. Nature (2011) 7.41
An Arabidopsis example of association mapping in structured samples. PLoS Genet (2006) 7.03
A distinct lineage of influenza A virus from bats. Proc Natl Acad Sci U S A (2012) 6.27
Recombination and linkage disequilibrium in Arabidopsis thaliana. Nat Genet (2007) 5.69
Trends in survival after in-hospital cardiac arrest. N Engl J Med (2012) 5.67
Characterization of human metapneumoviruses isolated from patients in North America. J Infect Dis (2002) 5.64
Predicting hepatitis B virus-positive metastatic hepatocellular carcinomas using gene expression profiling and supervised machine learning. Nat Med (2003) 5.45
Prognostic accuracy of day versus night ambulatory blood pressure: a cohort study. Lancet (2007) 5.21
A high-resolution map of the three-dimensional chromatin interactome in human cells. Nature (2013) 5.18
Analysis and validation of proteomic data generated by tandem mass spectrometry. Nat Methods (2007) 5.10
The extent of linkage disequilibrium in Arabidopsis thaliana. Nat Genet (2002) 4.96
Yersinia YopJ acetylates and inhibits kinase activation by blocking phosphorylation. Science (2006) 4.71
A single IGF1 allele is a major determinant of small size in dogs. Science (2007) 4.68
The Arabidopsis lyrata genome sequence and the basis of rapid genome size change. Nat Genet (2011) 4.65
Human illness from avian influenza H7N3, British Columbia. Emerg Infect Dis (2004) 4.29
Genome-wide association mapping in Arabidopsis identifies previously known flowering time and pathogen resistance genes. PLoS Genet (2005) 4.25
Genomic scale profiling of nutrient and trace elements in Arabidopsis thaliana. Nat Biotechnol (2003) 4.20
Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy improves survival of patients with peritoneal carcinomatosis from gastric cancer: final results of a phase III randomized clinical trial. Ann Surg Oncol (2011) 4.16
New world bats harbor diverse influenza A viruses. PLoS Pathog (2013) 4.10
Evaluation of ranolazine in patients with type 2 diabetes mellitus and chronic stable angina: results from the TERISA randomized clinical trial (Type 2 Diabetes Evaluation of Ranolazine in Subjects With Chronic Stable Angina). J Am Coll Cardiol (2013) 3.90
Erk associates with and primes GSK-3beta for its inactivation resulting in upregulation of beta-catenin. Mol Cell (2005) 3.89
Association between the 2008-09 seasonal influenza vaccine and pandemic H1N1 illness during Spring-Summer 2009: four observational studies from Canada. PLoS Med (2010) 3.85
Long-term outcomes in elderly survivors of in-hospital cardiac arrest. N Engl J Med (2013) 3.85
Epigenomic analysis of multilineage differentiation of human embryonic stem cells. Cell (2013) 3.81
Natural selection shapes genome-wide patterns of copy-number polymorphism in Drosophila melanogaster. Science (2008) 3.71
SuperHirn - a novel tool for high resolution LC-MS-based peptide/protein profiling. Proteomics (2007) 3.60
Live dynamic imaging of caveolae pumping targeted antibody rapidly and specifically across endothelium in the lung. Nat Biotechnol (2007) 3.54
Regulation of Notch1 and Dll4 by vascular endothelial growth factor in arterial endothelial cells: implications for modulating arteriogenesis and angiogenesis. Mol Cell Biol (2003) 3.51
Genetic variants and risk of lung cancer in never smokers: a genome-wide association study. Lancet Oncol (2010) 3.49
AMPylation of Rho GTPases by Vibrio VopS disrupts effector binding and downstream signaling. Science (2008) 3.44
Ambulatory arterial stiffness index as a predictor of cardiovascular mortality in the Dublin Outcome Study. Hypertension (2006) 3.42
Role of FRIGIDA and FLOWERING LOCUS C in determining variation in flowering time of Arabidopsis. Plant Physiol (2005) 3.31
Human Bocavirus infection, Canada. Emerg Infect Dis (2006) 3.30
Pre-existing AAV capsid-specific CD8+ T cells are unable to eliminate AAV-transduced hepatocytes. Mol Ther (2007) 3.26
Genealogical trees, coalescent theory and the analysis of genetic polymorphisms. Nat Rev Genet (2002) 3.24
Subtractive proteomic mapping of the endothelial surface in lung and solid tumours for tissue-specific therapy. Nature (2004) 3.24
A Pseudomonas syringae effector inactivates MAPKs to suppress PAMP-induced immunity in plants. Cell Host Microbe (2007) 3.15
Single-nucleotide mutation rate increases close to insertions/deletions in eukaryotes. Nature (2008) 3.13
The scale of population structure in Arabidopsis thaliana. PLoS Genet (2010) 3.12
PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity. J Cell Biol (2014) 3.12
Triple reassortant H3N2 influenza A viruses, Canada, 2005. Emerg Infect Dis (2006) 3.05
LUX ARRHYTHMO encodes a Myb domain protein essential for circadian rhythms. Proc Natl Acad Sci U S A (2005) 3.04
An efficient multi-locus mixed-model approach for genome-wide association studies in structured populations. Nat Genet (2012) 3.03
Label-free, normalized quantification of complex mass spectrometry data for proteomic analysis. Nat Biotechnol (2009) 3.01
Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26. Nature (2013) 3.00
A nonparametric test reveals selection for rapid flowering in the Arabidopsis genome. PLoS Biol (2006) 2.98
Identification of a novel astrovirus (astrovirus VA1) associated with an outbreak of acute gastroenteritis. J Virol (2009) 2.96
A systematic map of genetic variation in Plasmodium falciparum. PLoS Pathog (2006) 2.92
Prognostic value of a microRNA signature in nasopharyngeal carcinoma: a microRNA expression analysis. Lancet Oncol (2012) 2.91
Natural variants of AtHKT1 enhance Na+ accumulation in two wild populations of Arabidopsis. PLoS Genet (2006) 2.91
Novel avian influenza H7N3 strain outbreak, British Columbia. Emerg Infect Dis (2004) 2.90
Masked hypertension in diabetes mellitus: treatment implications for clinical practice. Hypertension (2013) 2.89
Adaptation to climate across the Arabidopsis thaliana genome. Science (2011) 2.89
Haplotype block structure and its applications to association studies: power and study designs. Am J Hum Genet (2002) 2.88
Pseudomonas syringae effector AvrPto blocks innate immunity by targeting receptor kinases. Curr Biol (2007) 2.84
Nf1-dependent tumors require a microenvironment containing Nf1+/-- and c-kit-dependent bone marrow. Cell (2008) 2.84
Genome-wide patterns of genetic variation in worldwide Arabidopsis thaliana accessions from the RegMap panel. Nat Genet (2012) 2.78
Anterior chamber width measurement by high-speed optical coherence tomography. Ophthalmology (2005) 2.77
Adjust quality scores from alignment and improve sequencing accuracy. Nucleic Acids Res (2004) 2.76
Linkage and association mapping of Arabidopsis thaliana flowering time in nature. PLoS Genet (2010) 2.76
A large number of novel coding small open reading frames in the intergenic regions of the Arabidopsis thaliana genome are transcribed and/or under purifying selection. Genome Res (2007) 2.72
Recoding RNA editing of AZIN1 predisposes to hepatocellular carcinoma. Nat Med (2013) 2.70
A mixed-model approach for genome-wide association studies of correlated traits in structured populations. Nat Genet (2012) 2.69
Susceptibility to neurodegeneration in a glaucoma is modified by Bax gene dosage. PLoS Genet (2005) 2.68
Progressive ganglion cell loss and optic nerve degeneration in DBA/2J mice is variable and asymmetric. BMC Neurosci (2006) 2.68
A genome-wide survey of R gene polymorphisms in Arabidopsis. Plant Cell (2006) 2.64
Prognostic value of reading-to-reading blood pressure variability over 24 hours in 8938 subjects from 11 populations. Hypertension (2010) 2.64
Amplification of LAPTM4B and YWHAZ contributes to chemotherapy resistance and recurrence of breast cancer. Nat Med (2010) 2.62
Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. Nat Biotechnol (2004) 2.60
Clinical and molecular characterisation of hereditary dopamine transporter deficiency syndrome: an observational cohort and experimental study. Lancet Neurol (2010) 2.60
Component-specific effectiveness of trivalent influenza vaccine as monitored through a sentinel surveillance network in Canada, 2006-2007. J Infect Dis (2009) 2.59
Signature of balancing selection in Arabidopsis. Proc Natl Acad Sci U S A (2002) 2.52
Association mapping of local climate-sensitive quantitative trait loci in Arabidopsis thaliana. Proc Natl Acad Sci U S A (2010) 2.51