Published in Mol Biol Evol on November 17, 2010
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Phylogenetic relationships within the Opisthokonta based on phylogenomic analyses of conserved single-copy protein domains. Mol Biol Evol (2011) 1.62
Hydrogen peroxide sensing, signaling and regulation of transcription factors. Redox Biol (2014) 1.54
The Capsaspora genome reveals a complex unicellular prehistory of animals. Nat Commun (2013) 1.39
Regulated aggregative multicellularity in a close unicellular relative of metazoa. Elife (2013) 1.18
Premetazoan origin of the hippo signaling pathway. Cell Rep (2011) 1.12
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NOL11, implicated in the pathogenesis of North American Indian childhood cirrhosis, is required for pre-rRNA transcription and processing. PLoS Genet (2012) 1.07
The evolution of the Wnt pathway. Cold Spring Harb Perspect Biol (2012) 1.06
Evolution and classification of myosins, a paneukaryotic whole-genome approach. Genome Biol Evol (2014) 1.02
Transcription factor evolution in eukaryotes and the assembly of the regulatory toolkit in multicellular lineages. Proc Natl Acad Sci U S A (2013) 1.01
Premetazoan ancestry of the Myc-Max network. Mol Biol Evol (2011) 0.98
A domain-centric solution to functional genomics via dcGO Predictor. BMC Bioinformatics (2013) 0.95
Gastric pouches and the mucociliary sole: setting the stage for nervous system evolution. Philos Trans R Soc Lond B Biol Sci (2015) 0.95
Genome-wide analysis of the sox family in the calcareous sponge Sycon ciliatum: multiple genes with unique expression patterns. Evodevo (2012) 0.90
Phylogenetic analysis of CDK and cyclin proteins in premetazoan lineages. BMC Evol Biol (2014) 0.90
Evolution of the animal apoptosis network. Cold Spring Harb Perspect Biol (2013) 0.89
Cellular and molecular processes leading to embryo formation in sponges: evidences for high conservation of processes throughout animal evolution. Dev Genes Evol (2012) 0.89
Early evolution of the T-box transcription factor family. Proc Natl Acad Sci U S A (2013) 0.87
Transcription factor networks directing the development, function, and evolution of innate lymphoid effectors. Annu Rev Immunol (2015) 0.87
Understanding the evolution and development of neurosensory transcription factors of the ear to enhance therapeutic translation. Cell Tissue Res (2012) 0.85
The Dynamic Regulatory Genome of Capsaspora and the Origin of Animal Multicellularity. Cell (2016) 0.85
The evolution and origin of animal Toll-like receptor signaling pathway revealed by network-level molecular evolutionary analyses. PLoS One (2012) 0.85
A broad genomic survey reveals multiple origins and frequent losses in the evolution of respiratory hemerythrins and hemocyanins. Genome Biol Evol (2013) 0.84
Early evolution of the eukaryotic Ca2+ signaling machinery: conservation of the CatSper channel complex. Mol Biol Evol (2014) 0.84
The mysterious evolutionary origin for the GNE gene and the root of bilateria. Mol Biol Evol (2011) 0.83
Two polymorphic residues account for the differences in DNA binding and transcriptional activation by NF-κB proteins encoded by naturally occurring alleles in Nematostella vectensis. J Mol Evol (2011) 0.83
The multicellularity genes of dictyostelid social amoebas. Nat Commun (2016) 0.82
Insights into the early evolution of animal calcium signaling machinery: a unicellular point of view. Cell Calcium (2014) 0.82
Expression of multiple Sox genes through embryonic development in the ctenophore Mnemiopsis leidyi is spatially restricted to zones of cell proliferation. Evodevo (2014) 0.82
Development of ichthyosporeans sheds light on the origin of metazoan multicellularity. Dev Biol (2013) 0.82
Evolutionarily ancient association of the FoxJ1 transcription factor with the motile ciliogenic program. PLoS Genet (2012) 0.82
Emergence and subsequent functional specialization of kindlins during evolution of cell adhesiveness. Mol Biol Cell (2014) 0.80
Evolution of lysine acetylation in the RNA polymerase II C-terminal domain. BMC Evol Biol (2015) 0.80
The functions of grainy head-like proteins in animals and fungi and the evolution of apical extracellular barriers. PLoS One (2012) 0.80
Metabolic and chaperone gene loss marks the origin of animals: evidence for Hsp104 and Hsp78 chaperones sharing mitochondrial enzymes as clients. PLoS One (2015) 0.80
Phylogenetic evidence for the modular evolution of metazoan signalling pathways. Philos Trans R Soc Lond B Biol Sci (2017) 0.79
Evolution of transcription factor function as a mechanism for changing metazoan developmental gene regulatory networks. Evodevo (2015) 0.79
Tracing the Evolutionary History of Inositol, 1, 4, 5-Trisphosphate Receptor: Insights from Analyses of Capsaspora owczarzaki Ca2+ Release Channel Orthologs. Mol Biol Evol (2015) 0.78
Conservation and divergence of bHLH genes in the calcisponge Sycon ciliatum. Evodevo (2016) 0.77
In vitro site selection of a consensus binding site for the Drosophila melanogaster Tbx20 homolog midline. PLoS One (2012) 0.77
Complex transcriptional regulation and independent evolution of fungal-like traits in a relative of animals. Elife (2015) 0.77
Understanding "green" multicellularity: do seaweeds hold the key? Front Plant Sci (2015) 0.77
Developmental control of transcriptional and proliferative potency during the evolutionary emergence of animals. Dev Dyn (2015) 0.76
Evolution of Prdm Genes in Animals: Insights from Comparative Genomics. Mol Biol Evol (2015) 0.76
Aryl hydrocarbon receptor (AHR) in the cnidarian Nematostella vectensis: comparative expression, protein interactions, and ligand binding. Dev Genes Evol (2013) 0.76
Regulation of Src and Csk nonreceptor tyrosine kinases in the filasterean Ministeria vibrans. Biochemistry (2014) 0.76
Diversity as Opportunity: Insights from 600 Million Years of AHR Evolution. Curr Opin Toxicol (2017) 0.76
The holozoan Capsaspora owczarzaki possesses a diverse complement of active transposable element families. Genome Biol Evol (2014) 0.75
In silico resurrection of the major vault protein suggests it is ancestral in modern eukaryotes. Genome Biol Evol (2013) 0.75
Evolutionary Changes on the Way to Clathrin-Mediated Endocytosis in Animals. Genome Biol Evol (2016) 0.75
The Unicellular Ancestry of Groucho-Mediated Repression and the Origins of Metazoan Transcription Factors. Genome Biol Evol (2016) 0.75
The diversification of the basic leucine zipper family in eukaryotes correlates with the evolution of multicellularity. BMC Evol Biol (2016) 0.75
The characterization of macroH2A beyond vertebrates supports an ancestral origin and conserved role for histone variants in chromatin. Epigenetics (2016) 0.75
Innovation and constraint leading to complex multicellularity in the Ascomycota. Nat Commun (2017) 0.75
Ecological and evolutionary significance of novel protist lineages. Eur J Protistol (2016) 0.75
The origin of Metazoa: a unicellular perspective. Nat Rev Genet (2017) 0.75
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MAFFT version 5: improvement in accuracy of multiple sequence alignment. Nucleic Acids Res (2005) 31.64
Signaling to NF-kappaB. Genes Dev (2004) 19.78
Stats: transcriptional control and biological impact. Nat Rev Mol Cell Biol (2002) 15.33
CONSEL: for assessing the confidence of phylogenetic tree selection. Bioinformatics (2001) 11.90
CBP/p300 in cell growth, transformation, and development. Genes Dev (2000) 10.76
Sea anemone genome reveals ancestral eumetazoan gene repertoire and genomic organization. Science (2007) 9.79
Phytophthora genome sequences uncover evolutionary origins and mechanisms of pathogenesis. Science (2006) 6.74
The genome of the choanoflagellate Monosiga brevicollis and the origin of metazoans. Nature (2008) 6.69
NFAT proteins: key regulators of T-cell development and function. Nat Rev Immunol (2005) 6.25
The Amphimedon queenslandica genome and the evolution of animal complexity. Nature (2010) 5.11
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MEF2: a central regulator of diverse developmental programs. Development (2007) 4.70
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An ancestral MADS-box gene duplication occurred before the divergence of plants and animals. Proc Natl Acad Sci U S A (2000) 2.49
A phylogenomic investigation into the origin of metazoa. Mol Biol Evol (2008) 2.32
Phylogenomics reveals a new 'megagroup' including most photosynthetic eukaryotes. Biol Lett (2008) 2.30
Convergent evolution of chromosomal sex-determining regions in the animal and fungal kingdoms. PLoS Biol (2004) 2.22
Crystallographic structure of the T domain-DNA complex of the Brachyury transcription factor. Nature (1997) 2.20
Churchill, a zinc finger transcriptional activator, regulates the transition between gastrulation and neurulation. Cell (2003) 2.10
Origin and diversification of basic-helix-loop-helix proteins in plants. Mol Biol Evol (2009) 2.03
Genesis and expansion of metazoan transcription factor gene classes. Mol Biol Evol (2008) 2.01
The protist, Monosiga brevicollis, has a tyrosine kinase signaling network more elaborate and diverse than found in any known metazoan. Proc Natl Acad Sci U S A (2008) 2.00
Origin and diversification of the basic helix-loop-helix gene family in metazoans: insights from comparative genomics. BMC Evol Biol (2007) 1.98
The origins of multicellularity: a multi-taxon genome initiative. Trends Genet (2007) 1.90
Multigene phylogeny of choanozoa and the origin of animals. PLoS One (2008) 1.90
The premetazoan ancestry of cadherins. Science (2008) 1.89
The Saccharomyces cerevisiae MADS-box transcription factor Rlm1 is a target for the Mpk1 mitogen-activated protein kinase pathway. Mol Cell Biol (1997) 1.89
The origins of multicellularity and the early history of the genetic toolkit for animal development. Annu Rev Genet (2008) 1.89
An overview of the basic helix-loop-helix proteins. Genome Biol (2004) 1.85
Transforming growth factor-beta stimulates p300-dependent RUNX3 acetylation, which inhibits ubiquitination-mediated degradation. J Biol Chem (2004) 1.84
Improvement in the accuracy of multiple sequence alignment program MAFFT. Genome Inform (2005) 1.83
Ancient origin of the integrin-mediated adhesion and signaling machinery. Proc Natl Acad Sci U S A (2010) 1.81
p300/CBP/p53 interaction and regulation of the p53 response. Eur J Biochem (2001) 1.77
A comprehensive classification and evolutionary analysis of plant homeobox genes. Mol Biol Evol (2009) 1.74
T-box genes: what they do and how they do it. Trends Genet (1999) 1.73
The dictyostelium kinome--analysis of the protein kinases from a simple model organism. PLoS Genet (2006) 1.69
Structural basis for the diversity of DNA recognition by bZIP transcription factors. Nat Struct Biol (2000) 1.63
Runx transcription factors and the developmental balance between cell proliferation and differentiation. Cell Biol Int (2003) 1.61
Mechanisms of regulatory diversity within the p53 transcriptional network. Oncogene (2008) 1.57
Evolution of homeobox genes: Q50 Paired-like genes founded the Paired class. Dev Genes Evol (1999) 1.55
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CBP and p300 are cytoplasmic E4 polyubiquitin ligases for p53. Proc Natl Acad Sci U S A (2009) 1.53
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Phylogeny of the "forgotten" cellular slime mold, Fonticula alba, reveals a key evolutionary branch within Opisthokonta. Mol Biol Evol (2009) 1.48
The HMG-box: a versatile protein domain occurring in a wide variety of DNA-binding proteins. Cell Mol Life Sci (2007) 1.46
Comprehensive analysis of animal TALE homeobox genes: new conserved motifs and cases of accelerated evolution. J Mol Evol (2007) 1.44
SH2 signaling in a lower eukaryote: a STAT protein that regulates stalk cell differentiation in dictyostelium. Cell (1997) 1.38
Cross-species annotation of basic leucine zipper factor interactions: Insight into the evolution of closed interaction networks. Mol Biol Evol (2006) 1.37
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Phylogenomic analyses predict sistergroup relationship of nucleariids and fungi and paraphyly of zygomycetes with significant support. BMC Evol Biol (2009) 1.31
Evolutionary position of breviate amoebae and the primary eukaryote divergence. Proc Biol Sci (2009) 1.31
Homeodomain proteins belong to the ancestral molecular toolkit of eukaryotes. Evol Dev (2007) 1.26
Mechanisms of transcriptional regulation by Runt domain proteins. Semin Cell Dev Biol (2000) 1.24
Structural basis for recruitment of CBP/p300 coactivators by STAT1 and STAT2 transactivation domains. EMBO J (2009) 1.23
The p53 response: emerging levels of co-factor complexity. Biochem Biophys Res Commun (2005) 1.22
Forkhead transcription factors II. Cell (2007) 1.21
Lineage-specific and ubiquitous biological roles of the mammalian transcription factor LSF. Gene (2004) 1.21
SnapShot: forkhead transcription factors I. Cell (2007) 1.20
The ancestral role of Brachyury: expression of NemBra1 in the basal cnidarian Nematostella vectensis (Anthozoa). Dev Genes Evol (2002) 1.17
Tissue-specific splicing and functions of the Drosophila transcription factor Grainyhead. Mol Cell Biol (1997) 1.15
Early diversification and complex evolutionary history of the p53 tumor suppressor gene family. Dev Genes Evol (2007) 1.13
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The evolution of Runx genes I. A comparative study of sequences from phylogenetically diverse model organisms. BMC Evol Biol (2003) 1.11
Redox regulation of the DNA binding activity in transcription factor PEBP2. The roles of two conserved cysteine residues. J Biol Chem (1997) 1.09
Evolution of the MAGUK protein gene family in premetazoan lineages. BMC Evol Biol (2010) 1.07
Capsaspora owczarzaki is an independent opisthokont lineage. Curr Biol (2004) 1.07
Fungal mating-type loci. Curr Biol (2003) 1.01
Isolation and characterization of two T-box genes from sponges, the phylogenetically oldest metazoan taxon. Dev Genes Evol (2003) 0.99
Evolutionary genomics of the Fox genes: origin of gene families and the ancestry of gene clusters. Genomics (2009) 0.98
A new family of transcription factors. Development (2008) 0.98
The evolutionary origin of the Runx/CBFbeta transcription factors--studies of the most basal metazoans. BMC Evol Biol (2008) 0.97
The transcription factor NF-kappaB in the demosponge Amphimedon queenslandica: insights on the evolutionary origin of the Rel homology domain. Dev Genes Evol (2008) 0.96
p53 recruitment of CREB binding protein mediated through phosphorylated CREB: a novel pathway of tumor suppressor regulation. Mol Cell Biol (2000) 0.95
Role of basic leucine zipper proteins in transcriptional regulation of the steroidogenic acute regulatory protein gene. Mol Cell Endocrinol (2008) 0.95
Ancient divergence of animal protein tyrosine kinase genes demonstrated by a gene family tree including choanoflagellate genes. FEBS Lett (2008) 0.95
Evolution of Brachyury proteins: identification of a novel regulatory domain conserved within Bilateria. Dev Biol (2003) 0.95
Two of four alternatively spliced isoforms of RUNX2 control osteocalcin gene expression in human osteoblast cells. Gene (2008) 0.94
The longevity assurance homologue of yeast lag1 (Lass) gene family (review). Int J Mol Med (2009) 0.92
Dual regulation of a Dictyostelium STAT by cGMP and Ca2+ signalling. J Cell Sci (2010) 0.90
Divergent functions of two ancient Hydra Brachyury paralogues suggest specific roles for their C-terminal domains in tissue fate induction. Development (2007) 0.90
The evolutionary diversification of LSF and Grainyhead transcription factors preceded the radiation of basal animal lineages. BMC Evol Biol (2010) 0.88
Clues to the evolution of complex signaling machinery. Proc Natl Acad Sci U S A (2008) 0.85
Churchill regulates cell movement and mesoderm specification by repressing Nodal signaling. BMC Dev Biol (2007) 0.84
Dictyostelium kinase DPYK3 negatively regulates STATc signaling in cell fate decision. Dev Growth Differ (2008) 0.82
The evolutionary history of lysine biosynthesis pathways within eukaryotes. J Mol Evol (2009) 0.82
Expression pattern of the Brachyury and Tbx2 homologues from the sponge Suberites domuncula. Biol Cell (2005) 0.81
The evolution of Runx genes II. The C-terminal Groucho recruitment motif is present in both eumetazoans and homoscleromorphs but absent in a haplosclerid demosponge. BMC Res Notes (2009) 0.78