Published in Science on February 15, 2008
The Amphimedon queenslandica genome and the evolution of animal complexity. Nature (2010) 5.11
Adherens junctions: from molecules to morphogenesis. Nat Rev Mol Cell Biol (2010) 3.97
Noncoding RNA in development. Mamm Genome (2008) 3.42
An epithelial tissue in Dictyostelium challenges the traditional origin of metazoan multicellularity. Bioessays (2012) 2.81
The protist, Monosiga brevicollis, has a tyrosine kinase signaling network more elaborate and diverse than found in any known metazoan. Proc Natl Acad Sci U S A (2008) 2.00
Intercellular junction assembly, dynamics, and homeostasis. Cold Spring Harb Perspect Biol (2010) 1.96
Ancient origin of the integrin-mediated adhesion and signaling machinery. Proc Natl Acad Sci U S A (2010) 1.81
Thinking outside the cell: how cadherins drive adhesion. Trends Cell Biol (2012) 1.72
The hypoxia-inducible transcription factor pathway regulates oxygen sensing in the simplest animal, Trichoplax adhaerens. EMBO Rep (2010) 1.62
Merlin and the ERM proteins--regulators of receptor distribution and signaling at the cell cortex. Trends Cell Biol (2009) 1.54
Cell differentiation and morphogenesis in the colony-forming choanoflagellate Salpingoeca rosetta. Dev Biol (2011) 1.53
Skin-derived cues control arborization of sensory dendrites in Caenorhabditis elegans. Cell (2013) 1.47
Unexpected repertoire of metazoan transcription factors in the unicellular holozoan Capsaspora owczarzaki. Mol Biol Evol (2010) 1.43
Premetazoan genome evolution and the regulation of cell differentiation in the choanoflagellate Salpingoeca rosetta. Genome Biol (2013) 1.41
A systems biology approach for the investigation of the heparin/heparan sulfate interactome. J Biol Chem (2011) 1.39
A polarized epithelium organized by beta- and alpha-catenin predates cadherin and metazoan origins. Science (2011) 1.32
Evolution: structural and functional diversity of cadherin at the adherens junction. J Cell Biol (2011) 1.22
Origin of metazoan cadherin diversity and the antiquity of the classical cadherin/β-catenin complex. Proc Natl Acad Sci U S A (2012) 1.22
Regulated aggregative multicellularity in a close unicellular relative of metazoa. Elife (2013) 1.18
Improved use of a public good selects for the evolution of undifferentiated multicellularity. Elife (2013) 1.16
Evolution of the metazoan-specific importin alpha gene family. J Mol Evol (2009) 1.16
Evolution of the MAGUK protein gene family in premetazoan lineages. BMC Evol Biol (2010) 1.07
The evolution of the Wnt pathway. Cold Spring Harb Perspect Biol (2012) 1.06
Diverse evolutionary paths to cell adhesion. Trends Cell Biol (2010) 1.05
Origins and evolution of the formin multigene family that is involved in the formation of actin filaments. Mol Biol Evol (2008) 1.03
WNT/beta-catenin signalling and epithelial patterning in the homoscleromorph sponge Oscarella. PLoS One (2009) 1.03
The Rosetteless gene controls development in the choanoflagellate S. rosetta. Elife (2014) 1.01
The molecular evolution of the p120-catenin subfamily and its functional associations. PLoS One (2010) 0.98
Crystal structures of Drosophila N-cadherin ectodomain regions reveal a widely used class of Ca²+-free interdomain linkers. Proc Natl Acad Sci U S A (2011) 0.96
Coiled-coil proteins facilitated the functional expansion of the centrosome. PLoS Comput Biol (2014) 0.95
Phylogenetic analysis of the teneurins: conserved features and premetazoan ancestry. Mol Biol Evol (2011) 0.95
The deuterostome context of chordate origins. Nature (2015) 0.93
Synapse adhesion: a dynamic equilibrium conferring stability and flexibility. Curr Opin Neurobiol (2011) 0.90
Convergent evolution of RFX transcription factors and ciliary genes predated the origin of metazoans. BMC Evol Biol (2010) 0.90
Phylogenetic analysis of CDK and cyclin proteins in premetazoan lineages. BMC Evol Biol (2014) 0.90
Prey capture and phagocytosis in the choanoflagellate Salpingoeca rosetta. PLoS One (2014) 0.89
Discovery and characterization of cadherin domains in Saccharophagus degradans 2-40. J Bacteriol (2009) 0.88
The evolution of the dystroglycan complex, a major mediator of muscle integrity. Biol Open (2015) 0.85
Dynamic self-guiding analysis of Alzheimer's disease. Oncotarget (2015) 0.84
The evolutionary origin of epithelial cell-cell adhesion mechanisms. Curr Top Membr (2013) 0.84
Integrin-mediated adhesion complex: Cooption of signaling systems at the dawn of Metazoa. Commun Integr Biol (2010) 0.82
Bacterial influences on animal origins. Cold Spring Harb Perspect Biol (2014) 0.81
Molecular evolution of the Yap/Yorkie proto-oncogene and elucidation of its core transcriptional program. Mol Biol Evol (2014) 0.80
Cadherin 23-like polypeptide in hair bundle mechanoreceptors of sea anemones. J Comp Physiol A Neuroethol Sens Neural Behav Physiol (2008) 0.79
Pre-metazoan origins and evolution of the cadherin adhesome. Biol Open (2014) 0.78
Stepwise Evolution of Coral Biomineralization Revealed with Genome-Wide Proteomics and Transcriptomics. PLoS One (2016) 0.77
Cadherin-based transsynaptic networks in establishing and modifying neural connectivity. Curr Top Dev Biol (2015) 0.77
Understanding "green" multicellularity: do seaweeds hold the key? Front Plant Sci (2015) 0.77
'Biogeneric' developmental processes: drivers of major transitions in animal evolution. Philos Trans R Soc Lond B Biol Sci (2016) 0.76
Development of cell differentiation in the transition to multicellularity: a dynamical modeling approach. Front Microbiol (2015) 0.76
Axial protocadherin (AXPC) regulates cell fate during notochordal morphogenesis. Dev Dyn (2011) 0.76
Notch-Mediated Cell Adhesion. Biology (Basel) (2016) 0.76
The Evolution of the Secreted Regulatory Protein Progranulin. PLoS One (2015) 0.76
Characterization of the Cadherin-Catenin Complex of the Sea Anemone Nematostella vectensis and Implications for the Evolution of Metazoan Cell-Cell Adhesion. Mol Biol Evol (2016) 0.75
E-cadherin roles in animal biology: A perspective on thyroid hormone-influence. Cell Commun Signal (2016) 0.75
Forward genetics for back-in-time questions. Elife (2014) 0.75
The origin of Metazoa: a unicellular perspective. Nat Rev Genet (2017) 0.75
Genome-scale approaches to resolving incongruence in molecular phylogenies. Nature (2003) 10.73
Early origins and evolution of microRNAs and Piwi-interacting RNAs in animals. Nature (2008) 6.81
Animals in a bacterial world, a new imperative for the life sciences. Proc Natl Acad Sci U S A (2013) 5.03
Early evolution of animal cell signaling and adhesion genes. Proc Natl Acad Sci U S A (2006) 2.20
The brain-derived neurotrophic factor gene confers susceptibility to bipolar disorder: evidence from a family-based association study. Am J Hum Genet (2002) 1.98
The origins of multicellularity: a multi-taxon genome initiative. Trends Genet (2007) 1.90
Ancient origin of the integrin-mediated adhesion and signaling machinery. Proc Natl Acad Sci U S A (2010) 1.81
A bacterial sulfonolipid triggers multicellular development in the closest living relatives of animals. Elife (2012) 1.72
Dopamine for "wanting" and opioids for "liking": a comparison of obese adults with and without binge eating. Obesity (Silver Spring) (2009) 1.65
Evidence for sex and recombination in the choanoflagellate Salpingoeca rosetta. Curr Biol (2013) 1.55
Cell differentiation and morphogenesis in the colony-forming choanoflagellate Salpingoeca rosetta. Dev Biol (2011) 1.53
Premetazoan genome evolution and the regulation of cell differentiation in the choanoflagellate Salpingoeca rosetta. Genome Biol (2013) 1.41
The genomic and cellular foundations of animal origins. Annu Rev Genet (2013) 1.33
Multicellular development in a choanoflagellate. Curr Biol (2010) 1.29
Conflicting phylogenetic signals at the base of the metazoan tree. Evol Dev (2003) 1.24
Origin of metazoan cadherin diversity and the antiquity of the classical cadherin/β-catenin complex. Proc Natl Acad Sci U S A (2012) 1.22
N-methyl-D-aspartate receptor NR2B subunit gene GRIN2B in schizophrenia and bipolar disorder: Polymorphisms and mRNA levels. Schizophr Res (2006) 1.18
Sterols in a unicellular relative of the metazoans. Proc Natl Acad Sci U S A (2008) 1.18
Signaling properties of a non-metazoan Src kinase and the evolutionary history of Src negative regulation. J Biol Chem (2008) 1.12
Serotonin transporter polymorphisms and persistent, pervasive childhood aggression. Am J Psychiatry (2006) 1.08
Complete genome sequence of Algoriphagus sp. PR1, bacterial prey of a colony-forming choanoflagellate. J Bacteriol (2010) 1.06
Diverse evolutionary paths to cell adhesion. Trends Cell Biol (2010) 1.05
Association of the Val158Met catechol O-methyltransferase genetic polymorphism with panic disorder. Neuropsychopharmacology (2006) 1.01
Algoriphagus machipongonensis sp. nov., co-isolated with a colonial choanoflagellate. Int J Syst Evol Microbiol (2012) 1.00
Premetazoan ancestry of the Myc-Max network. Mol Biol Evol (2011) 0.98
Brain-derived neurotrophic factor (BDNF) gene and rapid-cycling bipolar disorder: family-based association study. Br J Psychiatry (2006) 0.96
Synthesis of the rosette-inducing factor RIF-1 and analogs. J Am Chem Soc (2014) 0.93
Genetic dissection of the sporulation protein SpoIIE and its role in asymmetric division in Bacillus subtilis. J Bacteriol (2005) 0.93
Possible association between the gamma-aminobutyric acid type B receptor 1 (GABBR1) gene and schizophrenia. Eur Neuropsychopharmacol (2005) 0.91
Association of the neurotrophic tyrosine kinase receptor 3 (NTRK3) gene and childhood-onset mood disorders. Am J Psychiatry (2008) 0.89
Association study of tardive dyskinesia and twelve DRD2 polymorphisms in schizophrenia patients. Int J Neuropsychopharmacol (2006) 0.88
No association between the Pro197Leu polymorphism in the glutathione peroxidase (GPX1) gene and schizophrenia. Psychiatr Genet (2004) 0.87
Suggestive association between the C825T polymorphism of the G-protein beta3 subunit gene (GNB3) and clinical improvement with antipsychotics in schizophrenia. Eur Neuropsychopharmacol (2005) 0.86
Insights into the origin of metazoan filopodia and microvilli. Mol Biol Evol (2013) 0.84
Association analyses of the DAOA/G30 and D-amino-acid oxidase genes in schizophrenia: further evidence for a role in schizophrenia. Neuromolecular Med (2007) 0.84
The Bipolar Association Case-Control Study (BACCS) and meta-analysis: No association with the 5,10-Methylenetetrahydrofolate reductase gene and bipolar disorder. Am J Med Genet B Neuropsychiatr Genet (2010) 0.84
Genetic association analysis of the glutathione peroxidase (GPX1) gene polymorphism (Pro197Leu) with tardive dyskinesia. Psychiatry Res (2006) 0.83
Dopaminergic system genes in childhood aggression: possible role for DRD2. World J Biol Psychiatry (2011) 0.82
Association study of neurotrophic tyrosine kinase receptor type 2 (NTRK2) and childhood-onset mood disorders. Am J Med Genet B Neuropsychiatr Genet (2005) 0.81
Association study of a novel functional polymorphism of the serotonin transporter gene in bipolar disorder and suicidal behaviour. Psychopharmacology (Berl) (2005) 0.80
Tagging SNP association study of the IL-1beta gene (IL1B) and childhood-onset mood disorders. Am J Med Genet B Neuropsychiatr Genet (2009) 0.79
Lack of association between the corticotrophin-releasing hormone receptor 2 gene and panic disorder. Psychiatr Genet (2006) 0.79
Genome scan in sibling pairs with juvenile-onset mood disorders: Evidence for linkage to 13q and Xq. Am J Med Genet B Neuropsychiatr Genet (2009) 0.79
G72/G30 (DAOA) and juvenile-onset mood disorders. Am J Med Genet B Neuropsychiatr Genet (2009) 0.79
Genetic study of BDNF, DRD3, and their interaction in tardive dyskinesia. Eur Neuropsychopharmacol (2009) 0.78
Genetic study of eight AKT1 gene polymorphisms and their interaction with DRD2 gene polymorphisms in tardive dyskinesia. Schizophr Res (2008) 0.78
Further evidence of MAO-A gene variants associated with bipolar disorder. Am J Med Genet B Neuropsychiatr Genet (2007) 0.78
Association analysis of DAOA and DAO in bipolar disorder: results from two independent case-control studies. Bipolar Disord (2010) 0.78
Association study of N-methyl-D-aspartate glutamate receptor subunit genes and childhood-onset mood disorders. Psychiatr Genet (2009) 0.78
Association study of the gamma-aminobutyric acid type a receptor gamma2 subunit gene with schizophrenia. Schizophr Res (2009) 0.77
Association study of serotonin system genes in childhood-onset mood disorder. Psychiatr Genet (2008) 0.76
GPR50 is not associated with childhood-onset mood disorders in a large sample of Hungarian families. Psychiatr Genet (2007) 0.76
Investigation of the genetic interaction between BDNF and DRD3 genes in suicidical behaviour in psychiatric disorders. World J Biol Psychiatry (2014) 0.75
Weak association of the platelet-derived growth factor beta (PDGFB) and PDGF receptor beta (PDGFRB) genes with schizophrenia and schizoaffective disorder. World J Biol Psychiatry (2010) 0.75
A linkage study between the GABAA beta2 and GABAA gamma2 subunit genes and major psychoses. CNS Spectr (2005) 0.75
No association between brain-derived neurotrophic factor gene and obsessive-compulsive disorder. Psychiatr Genet (2005) 0.75
Modern disposable hydrogel contact lens removal has a minimal effect on intraocular pressure. Ophthalmic Physiol Opt (2015) 0.75
Correction: Evolution of an ancient protein function involved in organized multicellularity in animals. Elife (2016) 0.75